clonazepam has been researched along with Cancer of Ovary in 2 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In prospective alternative crossover test, we confirmed significant superiority of a three-drug combination of clonazepam (C) lorazepam (L) and dexamethasone (D) to (L) and (D) to control vomiting induced by 50 mg/m CDDP containing chemotherapy for gynecological malignancies (p less than 0." | 7.68 | [Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting]. ( Asano, H; Hatae, M; Hokanishi, H; Mitsuo, M; Nakamura, Y; Onishi, Y; Sakurai, K, 1990) |
| "In prospective alternative crossover test, we confirmed significant superiority of a three-drug combination of clonazepam (C) lorazepam (L) and dexamethasone (D) to (L) and (D) to control vomiting induced by 50 mg/m CDDP containing chemotherapy for gynecological malignancies (p less than 0." | 3.68 | [Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting]. ( Asano, H; Hatae, M; Hokanishi, H; Mitsuo, M; Nakamura, Y; Onishi, Y; Sakurai, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eguchi, F | 1 |
| Shindo, M | 1 |
| Emoto, M | 1 |
| Mohtai, H | 1 |
| Hachisuga, T | 1 |
| Kawarabayashi, T | 1 |
| Shirakawa, K | 1 |
| Hatae, M | 1 |
| Nakamura, Y | 1 |
| Mitsuo, M | 1 |
| Sakurai, K | 1 |
| Asano, H | 1 |
| Onishi, Y | 1 |
| Hokanishi, H | 1 |
1 trial available for clonazepam and Cancer of Ovary
| Article | Year |
|---|---|
[The prevention of cancer chemotherapy-induced emesis with granisetron and clonazepam].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clonazepam; Drug Ad | 1995 |
1 other study available for clonazepam and Cancer of Ovary
| Article | Year |
|---|---|
[Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting].
Topics: Adult; Antiemetics; Cisplatin; Clonazepam; Dexamethasone; Diphenhydramine; Female; Humans; Metoclopr | 1990 |