clonazepam has been researched along with Brain Damage, Chronic in 5 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we determined whether chronic administration of common AEDs during early life alters cell proliferation and neurogenesis in the hippocampus." | 1.35 | Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain. ( Cai, F; Cao, J; Chen, J; Li, S; Zhang, X, 2009) |
| "A patient with long-standing intention myoclonus was treated with oral clonazepam, which resulted in clinical and electrophysiologic improvement as manifested by dramatic reduction in intention myoclonus and diminished amplitude of somatosensory evoked potentials after treatment." | 1.27 | Posttraumatic intention myoclonus. ( Bjork, RJ; Snyder, BD; Starosta-Rubinstein, S; Tulloch, JW, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 1 |
| Cai, F | 1 |
| Cao, J | 1 |
| Zhang, X | 1 |
| Li, S | 1 |
| Starosta-Rubinstein, S | 1 |
| Bjork, RJ | 1 |
| Snyder, BD | 1 |
| Tulloch, JW | 1 |
| Baraczka, K | 1 |
| Molnár, G | 1 |
| Hilkens, PH | 1 |
| de Weerd, AW | 1 |
| McNamara, ME | 1 |
| Fogel, BS | 1 |
5 other studies available for clonazepam and Brain Damage, Chronic
| Article | Year |
|---|---|
Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain.
Topics: Age Factors; Animals; Animals, Suckling; Anticonvulsants; Apoptosis; Brain Damage, Chronic; Carbamaz | 2009 |
Posttraumatic intention myoclonus.
Topics: 5-Hydroxytryptophan; Benzodiazepinones; Brain Damage, Chronic; Clonazepam; Evoked Potentials, Somato | 1983 |
Possible drug interaction in chronic treatment of epileptic patients: serum level studies.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Chronic Disease; Clonazepam; Drug Interac | 1980 |
Non-convulsive status epilepticus as cause for focal neurological deficit.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Damage, Chronic; Clonazepam; Diagnosis, Diffe | 1995 |
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencepha | 1990 |