Page last updated: 2024-10-25

clonazepam and Body Weight

clonazepam has been researched along with Body Weight in 6 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The aims of the present study were (1) to investigate and quantify the pharmacokinetics, including inter-occasion variability and covariate relationships, of busulphan in BMT patients and (2) to develop a user-friendly initial dosing and therapeutic drug monitoring (TDM) strategy for the treatment of those patients with busulphan."1.31Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients. ( Bekassy, A; Hassan, M; Hassan, Z; Jonsson, EN; Karlsson, MO; Ljungman, P; Nilsson, C; Oberg, G; Ringden, O; Sandström, M, 2001)
"When clonazepam was finally withdrawn, a self-limiting abstinence syndrome was observed in all dogs, consisting of behavioral alterations (listlessness, wet dog shakes, dorsal recumbency), tremor, a severe clonic-tonic seizure in 1 case, hyperthermia, and weight loss."1.27Physical dependence on clonazepam in dogs. ( Frey, HH; Scherkl, R, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schlapbach, LJ1
Sozzo, A1
Ramelli, G1
Bianchetti, MG1
Miller, ME1
Garland, WA1
Min, BH1
Ludwick, BT1
Ballard, RH1
Levy, RH1
Sandström, M1
Karlsson, MO1
Ljungman, P1
Hassan, Z1
Jonsson, EN1
Nilsson, C1
Ringden, O1
Oberg, G1
Bekassy, A1
Hassan, M1
Barnhill, JG1
Ciraulo, DA1
Greenblatt, DJ1
Faggart, MA1
Harmatz, JS1
Wang, L1
Huang, Z1
Scherkl, R1
Frey, HH1

Other Studies

6 other studies available for clonazepam and Body Weight

ArticleYear
Severe normotensive metabolic alkalosis in a 2-month-old boy with hyperekplexia.
    Journal of inherited metabolic disease, 2006, Volume: 29, Issue:1

    Topics: Alkalosis; Bicarbonates; Body Weight; Chlorides; Clonazepam; Family Health; Female; Hernia; Humans;

2006
Clonazepam acetylation in fast and slow acetylators.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:3

    Topics: Acetylation; Administration, Oral; Adult; Benzodiazepinones; Body Weight; Clonazepam; Dose-Response

1981
Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Area Un

2001
Benzodiazepine response and receptor binding after chronic ethanol ingestion in a mouse model.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: Alcoholism; Animals; Behavior, Animal; Benzodiazepines; Body Weight; Cerebral Cortex; Clonazepam; Di

1991
Effect of clonazepam on brain development of mice.
    Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:1

    Topics: Administration, Oral; Animals; Animals, Newborn; Body Weight; Brain; Clonazepam; Female; Learning; M

1990
Physical dependence on clonazepam in dogs.
    Pharmacology, 1986, Volume: 32, Issue:1

    Topics: Animals; Benzodiazepinones; Body Temperature; Body Weight; Clonazepam; Dogs; Female; Flumazenil; Mal

1986