clonazepam has been researched along with Bilateral Headache in 10 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At the therapeutic endpoint, clonazepam (N = 222) proved clinically and statistically superior to placebo (N = 216) in change in the number of panic attacks and in Clinical Global Impressions-Severity of Illness (CGI-S) and CGI-Change scores, Patient's Global Impression of Change scores, amount of fear and avoidance associated with phobic symptoms, and duration of anticipatory anxiety." | 9.09 | Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages. ( Moroz, G; Rosenbaum, JF, 1999) |
| "Clonazepam seems to be an effective drug in idiopathic trigeminal neuralgia." | 9.04 | Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study. ( Caccia, MR, 1975) |
| "At the therapeutic endpoint, clonazepam (N = 222) proved clinically and statistically superior to placebo (N = 216) in change in the number of panic attacks and in Clinical Global Impressions-Severity of Illness (CGI-S) and CGI-Change scores, Patient's Global Impression of Change scores, amount of fear and avoidance associated with phobic symptoms, and duration of anticipatory anxiety." | 5.09 | Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages. ( Moroz, G; Rosenbaum, JF, 1999) |
| "Clonazepam seems to be an effective drug in idiopathic trigeminal neuralgia." | 5.04 | Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study. ( Caccia, MR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sangalli, L | 1 |
| Miller, CS | 1 |
| Mawhinney, JA | 1 |
| Wilcock, C | 1 |
| Haboubi, H | 1 |
| Roshanzamir, S | 1 |
| Raudino, F | 1 |
| Ruaño, G | 1 |
| Blair, CL | 1 |
| Bower, B | 1 |
| Windemuth, A | 1 |
| Kocherla, M | 1 |
| Aleman, Y | 1 |
| Pearlson, G | 1 |
| Goethe, JW | 1 |
| Schwartz, HI | 1 |
| Moroz, G | 1 |
| Rosenbaum, JF | 1 |
| Caccia, MR | 1 |
| Klein, DS | 1 |
| Schmidt, RE | 1 |
| Eppel, AB | 1 |
| Diamond, S | 1 |
| Voto Bernales, J | 1 |
| Cruz, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| DNA Diagnostics for Minimizing Metabolic Side-Effects of Antipsychotics[NCT00752960] | 1,000 participants (Anticipated) | Observational | 2007-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for clonazepam and Bilateral Headache
| Article | Year |
|---|---|
Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages.
Topics: Adolescent; Adult; Aged; Agoraphobia; Ambulatory Care; Clonazepam; Comorbidity; Double-Blind Method; | 1999 |
Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study.
Topics: Adult; Aged; Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Female; Headache; Humans; Male | 1975 |
8 other studies available for clonazepam and Bilateral Headache
| Article | Year |
|---|---|
Low-dose naltrexone for treatment of burning mouth syndrome.
Topics: Burning Mouth Syndrome; Clonazepam; Female; Fibromyalgia; Headache; Humans; Middle Aged; Naltrexone; | 2023 |
Neurotropism of SARS-CoV-2: COVID-19 presenting with an acute manic episode.
Topics: Adult; Affective Symptoms; Betacoronavirus; Cerebrospinal Fluid; Clonazepam; Coronavirus Infections; | 2020 |
SUNCT: a new case with some unusual features.
Topics: Adult; Clonazepam; Conjunctival Diseases; GABA Modulators; Headache; Humans; Magnetic Resonance Imag | 2005 |
Somatic complications of psychotropic medications in a patient with multiple CYP2 drug metabolism deficiencies.
Topics: Clonazepam; Cytochrome P-450 Enzyme System; Female; GABA Modulators; Headache; Humans; Middle Aged; | 2007 |
Chronic headache resulting from postoperative supraorbital neuralgia.
Topics: Bupivacaine; Chronic Disease; Clonazepam; Female; Headache; Humans; Middle Aged; Nerve Block; Neural | 1991 |
Interaction between clonazepam and phenelzine.
Topics: Adult; Anxiety Disorders; Clonazepam; Drug Interactions; Female; Headache; Humans; Panic; Phenelzine | 1990 |
Headache due to altered sensory threshold. Drug therapy for often intractable deafferentation neuralgia.
Topics: Clonazepam; Headache; Humans | 1987 |
[Treatment of dysrhythmic migraines and other headaches with RO- 5-4023].
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Drug Evaluation; Electroencephalography; Female; Headach | 1974 |