clonazepam has been researched along with Basal Ganglia Diseases in 6 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Though both blepharospasm and OMD are thought to represent focal dystonia at different body sites, the extent of improvement achieved with these drugs at the dosage employed differed markedly." | 1.27 | Meige's syndrome: acute and chronic responses to clonazepan and anticholinergics. ( Giménez-Roldán, S; Hípola, D; Mateo, D, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Virmani, T | 1 |
| Greene, PE | 1 |
| Pearson, TS | 1 |
| Grosse, P | 1 |
| Edwards, M | 1 |
| Tijssen, MAJ | 1 |
| Schrag, A | 1 |
| Lees, AJ | 1 |
| Bhatia, KP | 1 |
| Brown, P | 1 |
| Hípola, D | 2 |
| Mateo, D | 2 |
| Giménez-Roldán, S | 2 |
| Chouinard, G | 1 |
| Ransmayr, G | 1 |
| Kleedorfer, B | 1 |
| Dierckx, RA | 1 |
| Poewe, W | 1 |
| Kemmler, GW | 1 |
| Gerstenbrand, F | 1 |
| Orbe, M | 1 |
| Muñoz-Blanco, JL | 1 |
2 trials available for clonazepam and Basal Ganglia Diseases
| Article | Year |
|---|---|
The use of benzodiazepines in the treatment of manic-depressive illness.
Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Basal Ga | 1988 |
Pharmacological study in Meige's syndrome with predominant blepharospasm.
Topics: Aged; Basal Ganglia Diseases; Blepharospasm; Clinical Trials as Topic; Clonazepam; Double-Blind Meth | 1988 |
4 other studies available for clonazepam and Basal Ganglia Diseases
| Article | Year |
|---|---|
Delayed onset of progressive chorea after acute basal ganglia injury.
Topics: Adult; Baclofen; Basal Ganglia Diseases; Chorea; Clonazepam; GABA Modulators; Humans; Male; Muscle R | 2013 |
Patterns of EMG-EMG coherence in limb dystonia.
Topics: Adult; Anterior Compartment Syndrome; Anti-Dyskinesia Agents; Anticonvulsants; Antiparkinson Agents; | 2004 |
Meige's syndrome: acute and chronic responses to clonazepan and anticholinergics.
Topics: Aged; Basal Ganglia Diseases; Benzodiazepinones; Clonazepam; Dystonia; Female; Follow-Up Studies; Hu | 1984 |
Acute pharmacologic tests in cranial dystonia.
Topics: Adult; Aged; Basal Ganglia Diseases; Clonazepam; Diagnosis, Differential; Double-Blind Method; Femal | 1988 |