clonazepam has been researched along with B16 Melanoma in 1 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we evaluated the effect of several ligands active at the central-type and peripheral-type benzodiazepine receptor (BzR) (clonazepam, diazepam, PK11195 and Ro5-4864) on the growth and differentiation of B16 melanoma cells." | 3.70 | Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells. ( Beery, E; Brenner, S; Gavish, M; Landau, M; Landau, O; Nordenberg, J; Wasseman, L; Weizman, A; Zoref-Shani, E, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Landau, M | 1 |
| Weizman, A | 1 |
| Zoref-Shani, E | 1 |
| Beery, E | 1 |
| Wasseman, L | 1 |
| Landau, O | 1 |
| Gavish, M | 1 |
| Brenner, S | 1 |
| Nordenberg, J | 1 |
1 other study available for clonazepam and B16 Melanoma
| Article | Year |
|---|---|
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells.
Topics: Animals; Antineoplastic Agents; Benzodiazepinones; Cell Cycle; Cell Differentiation; Cell Division; | 1998 |