clonazepam has been researched along with Autistic Disorder in 5 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "TRIM32-/- mouse is a novel autism model mouse." | 1.56 | Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling. ( Chen, H; Chen, JB; Chen, WJ; Fang, LP; Huang, W; Jia, WQ; Li, S; Li, YF; Liu, CF; Liu, JC; Ma, QH; Schachner, M; Schwamborn, JC; Wang, QQ; Wang, ZT; Xiao, ZC; Xu, GQ; Xu, RX; Zhang, Y; Zhen, XC; Zhu, JW; Zou, MM, 2020) |
| "One also had features of infantile autism." | 1.29 | Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs. ( Chesler, N; Christianson, AL; Kromberg, JG, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, JW | 1 |
| Zou, MM | 1 |
| Li, YF | 1 |
| Chen, WJ | 1 |
| Liu, JC | 1 |
| Chen, H | 1 |
| Fang, LP | 1 |
| Zhang, Y | 1 |
| Wang, ZT | 1 |
| Chen, JB | 1 |
| Huang, W | 1 |
| Li, S | 2 |
| Jia, WQ | 1 |
| Wang, QQ | 1 |
| Zhen, XC | 1 |
| Liu, CF | 1 |
| Xiao, ZC | 1 |
| Xu, GQ | 1 |
| Schwamborn, JC | 1 |
| Schachner, M | 1 |
| Ma, QH | 1 |
| Xu, RX | 1 |
| Han, S | 1 |
| Tai, C | 1 |
| Westenbroek, RE | 1 |
| Yu, FH | 1 |
| Cheah, CS | 1 |
| Potter, GB | 1 |
| Rubenstein, JL | 1 |
| Scheuer, T | 1 |
| de la Iglesia, HO | 1 |
| Catterall, WA | 1 |
| Christianson, AL | 1 |
| Chesler, N | 1 |
| Kromberg, JG | 1 |
| Thirumalai, SS | 1 |
| Shubin, RA | 1 |
| Robinson, R | 1 |
| Kehrer, HE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery In Indonesia Three Major Tertiary Hospitals: A Randomized Controlled Trial[NCT05795608] | 46 participants (Actual) | Interventional | 2015-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for clonazepam and Autistic Disorder
| Article | Year |
|---|---|
[Infantile autism and drug therapy].
Topics: Adolescent; Amitriptyline; Autistic Disorder; Child; Child, Preschool; Clinical Trials as Topic; Clo | 1978 |
4 other studies available for clonazepam and Autistic Disorder
| Article | Year |
|---|---|
Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling.
Topics: Animals; Autistic Disorder; Autophagy; Behavior, Animal; Cell Proliferation; Clonazepam; GABA-A Rece | 2020 |
Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.
Topics: Animals; Anxiety; Autistic Disorder; Clonazepam; Epilepsies, Myoclonic; GABA Modulators; GABAergic N | 2012 |
Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs.
Topics: Adult; Autistic Disorder; Child, Preschool; Clonazepam; Developmental Disabilities; Epilepsy; Family | 1994 |
Rapid eye movement sleep behavior disorder in children with autism.
Topics: Anticonvulsants; Autistic Disorder; Child; Child, Preschool; Clonazepam; Electroencephalography; Ele | 2002 |