clonazepam has been researched along with Atrial Fibrillation in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study direction and intensity of autonomic changes in patients with paroxysmal atrial fibrillation (PAF) treated with clonazepam and their dynamics during antiarrhythmic therapy." | 7.73 | [Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation]. ( Khaspekova, NB; Nedostup, AV; San'kova, TA; Solov'ëva, AD, 2005) |
| "To study the efficacy of clonazepam in patients with paroxysmal atrial fibrillation (PAF) with reference to their psychovegetative status." | 7.72 | [Use of clonazepam for treatment of patients with paroxysmal atrial fibrillation with regard to their psychoautonomic status]. ( Nedostup, AV; San'kova, TA; Solov'eva, AD, 2003) |
| "Determination of neurophysiological features of the disease course in patients with paroxysmal atrial fibrillation (AF); pathogenetic validation of use and assessment of therapeutic efficacy of clonazepam (an atypical agonist of benzodiazepine receptors) in combined antiarrhythmic therapy." | 5.12 | [New facts about pathogenesis of atrial fibrillation: correlation between changes in bioelectric brain activity and recurrence of atrial fibrillation paroxysms]. ( Fedorova, VI; Gordeev, SA; Nedostup, AV; Vasiukov, SS, 2007) |
| "To study direction and intensity of autonomic changes in patients with paroxysmal atrial fibrillation (PAF) treated with clonazepam and their dynamics during antiarrhythmic therapy." | 3.73 | [Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation]. ( Khaspekova, NB; Nedostup, AV; San'kova, TA; Solov'ëva, AD, 2005) |
| "To study the efficacy of clonazepam in patients with paroxysmal atrial fibrillation (PAF) with reference to their psychovegetative status." | 3.72 | [Use of clonazepam for treatment of patients with paroxysmal atrial fibrillation with regard to their psychoautonomic status]. ( Nedostup, AV; San'kova, TA; Solov'eva, AD, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nedostup, AV | 3 |
| Solov'eva, AD | 2 |
| San'kova, TA | 2 |
| Khaspekova, NB | 1 |
| Vasiukov, SS | 1 |
| Fedorova, VI | 1 |
| Gordeev, SA | 1 |
1 trial available for clonazepam and Atrial Fibrillation
| Article | Year |
|---|---|
[New facts about pathogenesis of atrial fibrillation: correlation between changes in bioelectric brain activity and recurrence of atrial fibrillation paroxysms].
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Atrial Fibrillation; Beta Rhythm; Brain; Clonaz | 2007 |
2 other studies available for clonazepam and Atrial Fibrillation
| Article | Year |
|---|---|
[Use of clonazepam for treatment of patients with paroxysmal atrial fibrillation with regard to their psychoautonomic status].
Topics: Adult; Aged; Anticonvulsants; Atrial Fibrillation; Autonomic Nervous System Diseases; Behavioral Sym | 2003 |
[Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Anticonvulsants; Atrial Fibrillation; Autonomic Nervous System; | 2005 |