clonazepam has been researched along with Apnea, Sleep in 11 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used ramelteon to treat two patients with secondary REM sleep behavior disorder (RBD) complications along with neurodegenerative diseases including multiple system atrophy and Parkinson's disease." | 7.79 | Use of ramelteon for the treatment of secondary REM sleep behavior disorder. ( Kawase, S; Nakashima, K; Nomura, T; Watanabe, Y, 2013) |
| "We used ramelteon to treat two patients with secondary REM sleep behavior disorder (RBD) complications along with neurodegenerative diseases including multiple system atrophy and Parkinson's disease." | 3.79 | Use of ramelteon for the treatment of secondary REM sleep behavior disorder. ( Kawase, S; Nakashima, K; Nomura, T; Watanabe, Y, 2013) |
| " An association between weight gain, obstructive sleep apnea, and lithium treatment is also illustrated." | 3.68 | Four cases of obstructive sleep apnea associated with treatment-resistant mania. ( Alpert, JE; Frankenburg, FR; Hudson, JI; Keck, PE; Strakowski, SM; Teschke, GC; Tohen, M; Wilson, DR, 1991) |
| " The present study aimed to compare nCPAP alone (n), nCPAP combined with clonazepam (n+c) and clonazepam alone (c) in patients with mild to moderate SAHS associated with high leg activity." | 2.70 | High leg motor activity in sleep apnea hypopnea patients: efficacy of clonazepam combined with nasal CPAP on polysomnographic variables. ( De Maertelaer, V; Kempenaers, Ch; Kerkhofs, M; Lanquart, JR; Linkowski, R; Noseda, A; Nouvelle, M, 2002) |
| "Clonazepam was stopped." | 1.36 | Late-onset nocturnal intractable seizure during sleep: what is the origin? ( Liesiene, V; Miliauskas, S; Sakalauskas, R; Zemaitis, M, 2010) |
| "Sleep-related eating disorders distinct from daytime eating disorders have recently been shown to be associated with sleepwalking (SW), periodic limb movement (PLM) disorder and triazolam abuse in a series of 19 adults." | 1.29 | Additional categories of sleep-related eating disorders and the current status of treatment. ( Hurwitz, TD; Mahowald, MW; O'Connor, KA; Schenck, CH, 1993) |
| "Treatment with clonazepam has abolished the nocturnal behavioural disturbance." | 1.29 | Conversion disorder revisited: severe parasomnia discovered. ( Bokey, K, 1993) |
| "In 100 consecutive adults who came to a sleep disorders center complaining of repeated nocturnal injury, polysomnographic study identified five disorders: night terrors/sleepwalking (N = 54), REM sleep behavior disorder (N = 36), dissociative disorders (N = 7), nocturnal seizures (N = 2), and sleep apnea (N = 1)." | 1.28 | A polysomnographic and clinical report on sleep-related injury in 100 adult patients. ( Bundlie, SR; Hurwitz, TD; Mahowald, MW; Milner, DM; Schenck, CH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nomura, T | 1 |
| Kawase, S | 1 |
| Watanabe, Y | 1 |
| Nakashima, K | 1 |
| Miliauskas, S | 1 |
| Liesiene, V | 1 |
| Zemaitis, M | 1 |
| Sakalauskas, R | 1 |
| Noseda, A | 1 |
| Nouvelle, M | 1 |
| Lanquart, JR | 1 |
| Kempenaers, Ch | 1 |
| De Maertelaer, V | 1 |
| Linkowski, R | 1 |
| Kerkhofs, M | 1 |
| Hochman, MS | 1 |
| Chediak, AD | 1 |
| Ziffer, JA | 1 |
| Schenck, CH | 2 |
| Hurwitz, TD | 2 |
| O'Connor, KA | 1 |
| Mahowald, MW | 2 |
| Bokey, K | 1 |
| Nofzinger, EA | 1 |
| Reynolds, CF | 1 |
| Morfis, L | 1 |
| Schwartz, RS | 1 |
| Cistulli, PA | 1 |
| Strakowski, SM | 1 |
| Hudson, JI | 1 |
| Keck, PE | 1 |
| Wilson, DR | 1 |
| Frankenburg, FR | 1 |
| Alpert, JE | 1 |
| Teschke, GC | 1 |
| Tohen, M | 1 |
| Milner, DM | 1 |
| Bundlie, SR | 1 |
| Guilleminault, C | 1 |
| Crowe, C | 1 |
| Quera-Salva, MA | 1 |
| Miles, L | 1 |
| Partinen, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Center, Open Label Prospective Observational Pilot Study to Evaluate the Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)[NCT05922995] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for clonazepam and Apnea, Sleep
| Article | Year |
|---|---|
High leg motor activity in sleep apnea hypopnea patients: efficacy of clonazepam combined with nasal CPAP on polysomnographic variables.
Topics: Analysis of Variance; Clonazepam; Combined Modality Therapy; Female; GABA Modulators; Humans; Male; | 2002 |
10 other studies available for clonazepam and Apnea, Sleep
| Article | Year |
|---|---|
Use of ramelteon for the treatment of secondary REM sleep behavior disorder.
Topics: Aged; Clonazepam; Female; Humans; Indenes; Male; Middle Aged; Multiple System Atrophy; Parkinson Dis | 2013 |
Late-onset nocturnal intractable seizure during sleep: what is the origin?
Topics: Anticonvulsants; Clonazepam; Epilepsy; Follow-Up Studies; Humans; Male; Middle Aged; Polysomnography | 2010 |
Hyperekplexia: report of a nonfamilial adult onset case associated with obstructive sleep apnea and abnormal brain nuclear tomography.
Topics: Brain; Carotid Artery, Internal; Clonazepam; Electroencephalography; Evoked Potentials, Somatosensor | 1994 |
Additional categories of sleep-related eating disorders and the current status of treatment.
Topics: Adult; Aged; Child, Preschool; Clinical Protocols; Clonazepam; Combined Modality Therapy; Dopamine A | 1993 |
Conversion disorder revisited: severe parasomnia discovered.
Topics: Arousal; Cerebral Cortex; Clonazepam; Combat Disorders; Conversion Disorder; Dreams; Evoked Potentia | 1993 |
Sleep impairment and daytime sleepiness in later life.
Topics: Aged; Clonazepam; Diagnosis, Differential; Humans; Male; Polysomnography; Positive-Pressure Respirat | 1996 |
REM sleep behaviour disorder: a treatable cause of falls in elderly people.
Topics: Accidental Falls; Aged; Clonazepam; Diagnosis, Differential; Female; Geriatric Assessment; Humans; P | 1997 |
Four cases of obstructive sleep apnea associated with treatment-resistant mania.
Topics: Adult; Bipolar Disorder; Clonazepam; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Mi | 1991 |
A polysomnographic and clinical report on sleep-related injury in 100 adult patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clonazepam; Dissociative Disorders; Female; Humans | 1989 |
Periodic leg movement, sleep fragmentation and central sleep apnoea in two cases: reduction with Clonazepam.
Topics: Adult; Clonazepam; Female; Humans; Leg; Male; Middle Aged; Myoclonus; Sleep Apnea Syndromes; Sleep W | 1988 |