clonazepam has been researched along with Anoxemia in 16 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-hypoxic myoclonus (PHM) is a rare neurological complication having two different variants depending on acute or chronic onset after cardiopulmonary resuscitation following cardiac arrest: myoclonic status epilepticus (MSE) and Lance-Adams syndrome (LAS) respectively." | 3.01 | Post-hypoxic myoclonus; what we know and gaps in knowledge. ( Ahmed, HS, 2023) |
| "Postanoxic myoclonus is a rare manifestation after an anoxic event, with fewer than 150 cases reported in the literature." | 1.40 | Postanoxic myoclonus: two case presentations and review of medical management. ( Budhram, A; Harvey, D; Lipson, D; Nesathurai, S; Rathbone, MP, 2014) |
| "A patient with posthypoxic cortical action myoclonus was studied using polygraphic EEG-EMG recording techniques and transcranial magnetic stimulation." | 1.33 | Rhythmic EMG and EEG activity during voluntary movement in posthypoxic cortical action myoclonus. ( Hashimoto, T; Tamagawa, A; Tsuji, S; Uozumi, T, 2005) |
| "Posthypoxic myoclonus is a rare complication of successful cardiopulmonary resusitation." | 1.28 | Posthypoxic myoclonus (the Lance-Adams syndrome) in the intensive care unit. ( Harper, SJ; Wilkes, RG, 1991) |
| "Chronic hypoxemia, hypercarbia, bronchospasm, and inadequate nutrition were present in all." | 1.28 | Movement disorder of premature infants with severe bronchopulmonary dysplasia: a new syndrome. ( Perlman, JM; Volpe, JJ, 1989) |
| "A patient with post-hypoxic myoclonus, sensitive to therapy with 5-hydroxytryptophan and clonazepam, was subjected to detailed electrophysiological investigation." | 1.26 | Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus. ( Adam, J; Chadwick, D; Hallett, M; Marsden, CD, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kane, JM | 1 |
| Baron, BM | 1 |
| Dudley, MW | 1 |
| Sorensen, SM | 1 |
| Staeger, MA | 1 |
| Miller, FP | 1 |
| Ahmed, HS | 1 |
| Budhram, A | 1 |
| Lipson, D | 1 |
| Nesathurai, S | 1 |
| Harvey, D | 1 |
| Rathbone, MP | 1 |
| Sharikabad, MN | 1 |
| Østbye, KM | 1 |
| Brørs, O | 1 |
| Martínez-Sánchez, M | 1 |
| Striggow, F | 1 |
| Schröder, UH | 1 |
| Kahlert, S | 1 |
| Reymann, KG | 1 |
| Reiser, G | 1 |
| Uozumi, T | 1 |
| Tamagawa, A | 1 |
| Hashimoto, T | 1 |
| Tsuji, S | 1 |
| Larner, AJ | 1 |
| Heafield, MT | 1 |
| Griffiths, EJ | 1 |
| Ocampo, CJ | 1 |
| Savage, JS | 1 |
| Rutter, GA | 1 |
| Hansford, RG | 1 |
| Stern, MD | 1 |
| Silverman, HS | 1 |
| Frucht, SJ | 1 |
| Hallett, M | 2 |
| Chadwick, D | 2 |
| Adam, J | 1 |
| Marsden, CD | 2 |
| Harper, SJ | 1 |
| Wilkes, RG | 1 |
| Sher, PK | 1 |
| Jenner, P | 1 |
| Fahn, S | 2 |
| Perlman, JM | 1 |
| Volpe, JJ | 1 |
2 reviews available for clonazepam and Anoxemia
| Article | Year |
|---|---|
Post-hypoxic myoclonus; what we know and gaps in knowledge.
Topics: Cardiopulmonary Resuscitation; Clonazepam; Humans; Hypoxia; Myoclonus; Syndrome; Valproic Acid | 2023 |
Posthypoxic action myoclonus: literature review update.
Topics: Adult; Clonazepam; Coma; Electroencephalography; Female; Functional Laterality; Heart Arrest; Humans | 1986 |
14 other studies available for clonazepam and Anoxemia
| Article | Year |
|---|---|
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia | 1990 |
Postanoxic myoclonus: two case presentations and review of medical management.
Topics: Aged; Anticonvulsants; Clonazepam; Drug Therapy, Combination; Humans; Hypoxia; Levetiracetam; Male; | 2014 |
Effect of hydrogen peroxide on reoxygenation-induced Ca2+ accumulation in rat cardiomyocytes.
Topics: Adenosine Triphosphate; Animals; Buffers; Calcium; Clonazepam; Dose-Response Relationship, Drug; Flo | 2004 |
Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blocker | 2004 |
Rhythmic EMG and EEG activity during voluntary movement in posthypoxic cortical action myoclonus.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Electromyography; Humans; Hypoxi | 2005 |
Post anoxic action myoclonus.
Topics: Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Hypoxia; Male; Middle Aged; Pi | 1993 |
Mitochondrial calcium transporting pathways during hypoxia and reoxygenation in single rat cardiomyocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Size; Cells, Cultured; Clonazepam; Cytosol; Fluores | 1998 |
The clinical challenge of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Anticonvulsants; Clonazepam; Humans; Hypoxia; Levetiracetam; Myoclonus; Neuropr | 2002 |
Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Clonazepam; Electroencephalography; Evoked Potentials; Humans; Hypoxia; Male; M | 1977 |
Posthypoxic myoclonus (the Lance-Adams syndrome) in the intensive care unit.
Topics: Clonazepam; Critical Care; Diagnosis, Differential; Humans; Hypoxia; Male; Middle Aged; Myoclonus; R | 1991 |
The effects of acidosis on chronically hypoxic neurons in culture.
Topics: Acidosis; Animals; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Chroni | 1990 |
Treatment of posthypoxic action myoclonus: implications for the pathophysiology of the disorder.
Topics: 5-Hydroxytryptophan; Benzodiazepines; Clonazepam; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac | 1986 |
Newer drugs for posthypoxic action myoclonus: observations from a well-studied case.
Topics: Clonazepam; Drug Therapy, Combination; Estrogens, Conjugated (USP); Fasting; Female; Humans; Hydroxy | 1986 |
Movement disorder of premature infants with severe bronchopulmonary dysplasia: a new syndrome.
Topics: Bronchopulmonary Dysplasia; Clonazepam; Follow-Up Studies; Humans; Hypoxia; Infant, Newborn; Movemen | 1989 |