clonazepam has been researched along with Anankastic Personality in 30 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to examine the effects of memantine as an adjuvant treatment for obsessive compulsive (OC) symptoms in patients with bipolar disorder (BD) type I, manic phase." | 9.24 | Memantine as an Adjuvant Treatment for Obsessive Compulsive Symptoms in Manic Phase of Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Ghanizadeh, A; Jahromi, LR; Mowla, A; Sahraian, A, 2017) |
| "The combination of lithium+olanzapine+clonazepam decreased the symptoms of obsessive compulsive disorder in the patients with bipolar disorder type I." | 9.19 | Topiramate as an adjuvant treatment for obsessive compulsive symptoms in patients with bipolar disorder: a randomized double blind placebo controlled clinical trial. ( Akhondzadeh, S; Bigdeli, M; Ghanizadeh, A; Sahraian, A, 2014) |
| "Clonazepam has demonstrated effectiveness in several preliminary reports in treating OCD." | 6.71 | A double-blind, placebo-controlled trial of clonazepam in obsessive-compulsive disorder. ( Hollander, E; Kaplan, A; Stahl, SM, 2003) |
| "Clonazepam improvement was unrelated to changes in anxiety and occurred early in treatment." | 6.67 | Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder. ( Agras, WS; Hewlett, WA; Vinogradov, S, 1992) |
| "Clonazepam was effective not only in reducing anxiety symptoms, but also in lowering compulsions and obsessions frequency within 6 weeks with a drop in the Children's Yale-Brown Obsessive Compulsive Scale of 16 points." | 5.42 | [The Usefulness of Clonazepam as an Augmentative Treatment in a Case of Severe Childhood Onset Obsessive-Compulsive Disorder]. ( Belhaj, A; Ben Youssef, H; Bouasker, A; Bouden, A; Ghachem, R; Halayem, S; Othman, S; Tabbane, K, 2015) |
| "The aim of this study is to examine the effects of memantine as an adjuvant treatment for obsessive compulsive (OC) symptoms in patients with bipolar disorder (BD) type I, manic phase." | 5.24 | Memantine as an Adjuvant Treatment for Obsessive Compulsive Symptoms in Manic Phase of Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Ghanizadeh, A; Jahromi, LR; Mowla, A; Sahraian, A, 2017) |
| "The combination of lithium+olanzapine+clonazepam decreased the symptoms of obsessive compulsive disorder in the patients with bipolar disorder type I." | 5.19 | Topiramate as an adjuvant treatment for obsessive compulsive symptoms in patients with bipolar disorder: a randomized double blind placebo controlled clinical trial. ( Akhondzadeh, S; Bigdeli, M; Ghanizadeh, A; Sahraian, A, 2014) |
| " In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder." | 4.31 | Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales. ( Arikan, Z; Ertek, İE; Tamdemir, SE; Ünler, M, 2023) |
| "Clonazepam has demonstrated effectiveness in several preliminary reports in treating OCD." | 2.71 | A double-blind, placebo-controlled trial of clonazepam in obsessive-compulsive disorder. ( Hollander, E; Kaplan, A; Stahl, SM, 2003) |
| "Clonazepam improvement was unrelated to changes in anxiety and occurred early in treatment." | 2.67 | Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder. ( Agras, WS; Hewlett, WA; Vinogradov, S, 1992) |
| "Clonazepam was effective not only in reducing anxiety symptoms, but also in lowering compulsions and obsessions frequency within 6 weeks with a drop in the Children's Yale-Brown Obsessive Compulsive Scale of 16 points." | 1.42 | [The Usefulness of Clonazepam as an Augmentative Treatment in a Case of Severe Childhood Onset Obsessive-Compulsive Disorder]. ( Belhaj, A; Ben Youssef, H; Bouasker, A; Bouden, A; Ghachem, R; Halayem, S; Othman, S; Tabbane, K, 2015) |
| "Folie a deux (shared psychotic disorder) is often described in the context of schizophrenia." | 1.36 | Shared obsessive-compulsive disorder: broadening the concept of shared psychotic disorder. ( Greenberg, D; Jaworowski, S; Lerner, V; Mergui, J, 2010) |
| "Pica is a common disorder in childhood, however, in adults it is associated with mental retardation, psychosis and pregnancy." | 1.35 | Pica responding to SSRI: an OCD spectrum disorder? ( Bhatia, MS; Gupta, R, 2009) |
| "Patients with Tourette's syndrome often develop multiple psychopathological symptoms beyond the basic symptoms (motor and vocal tics)." | 1.31 | [Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear]. ( Barnett, W; Bednarz, K; Haisch, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 11 (36.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ünler, M | 1 |
| Tamdemir, SE | 1 |
| Ertek, İE | 1 |
| Arikan, Z | 1 |
| Sahraian, A | 3 |
| Ghahremanpouri, B | 1 |
| Mowla, A | 2 |
| Dwivedi, S | 1 |
| Kar, SK | 1 |
| Faye, A | 1 |
| Kirpekar, V | 1 |
| Tadke, R | 1 |
| Gawande, S | 1 |
| Bhave, S | 1 |
| Jain, S | 1 |
| Gupta, T | 1 |
| Nebhinani, N | 1 |
| Singhai, K | 1 |
| Suthar, N | 1 |
| Bigdeli, M | 1 |
| Ghanizadeh, A | 2 |
| Akhondzadeh, S | 1 |
| Santos, V | 1 |
| Nardi, AE | 1 |
| King, AL | 1 |
| Halayem, S | 1 |
| Othman, S | 1 |
| Ben Youssef, H | 1 |
| Belhaj, A | 1 |
| Bouasker, A | 1 |
| Ghachem, R | 1 |
| Tabbane, K | 1 |
| Bouden, A | 1 |
| Arikawa, A | 1 |
| Mito, H | 1 |
| Motoyama, M | 1 |
| Yamanishi, K | 1 |
| Hayashida, K | 1 |
| Maebayashi, K | 1 |
| Matsunaga, H | 1 |
| Jahromi, LR | 1 |
| Fontenelle, LF | 1 |
| Leite, MA | 1 |
| Mergui, J | 1 |
| Jaworowski, S | 1 |
| Greenberg, D | 1 |
| Lerner, V | 1 |
| Mahgoub, N | 1 |
| Asemota, B | 1 |
| Alexopoulos, GS | 1 |
| Korkmaz, S | 1 |
| Işik, U | 1 |
| Korkmaz, H | 1 |
| Bednarz, K | 1 |
| Haisch, S | 1 |
| Barnett, W | 1 |
| Hollander, E | 1 |
| Kaplan, A | 1 |
| Stahl, SM | 1 |
| Jenike, MA | 2 |
| Bhatia, MS | 1 |
| Gupta, R | 1 |
| Wickham, R | 1 |
| Varma, A | 1 |
| Rauch, SL | 1 |
| Dominguez, RA | 1 |
| Mestre, SM | 1 |
| Goodman, WK | 1 |
| McDougle, CJ | 2 |
| Barr, LC | 1 |
| Aronson, SC | 1 |
| Price, LH | 2 |
| Ross, DC | 1 |
| Piggott, LR | 1 |
| Carpenter, LL | 1 |
| Epperson, CN | 1 |
| Leonard, HL | 1 |
| Benazzi, F | 1 |
| Hewlett, WA | 2 |
| Vinogradov, S | 2 |
| Agras, WS | 2 |
| Bacher, NM | 1 |
| Bodkin, JA | 1 |
| White, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Initial Evaluation of Efficacy and Adverse Events of Single Lesions in Bilateral Ventral-capsular and Ventral Capsulotomy-striatal by Linear Accelerator Radiosurgery in Severe and Refractory Obsessive-compulsive Disorder[NCT02500888] | 10 participants (Anticipated) | Interventional | 2015-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for clonazepam and Anankastic Personality
| Article | Year |
|---|---|
Clinical practice. Obsessive-compulsive disorder.
Topics: Adult; Child; Clonazepam; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; GABA Modu | 2004 |
Managing the patient with treatment-resistant obsessive compulsive disorder: current strategies.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior Therapy; Buspirone; Clonazepam; Com | 1994 |
Management of treatment-refractory obsessive compulsive disorder patients.
Topics: Antipsychotic Agents; Behavior Therapy; Clomipramine; Clonazepam; Combined Modality Therapy; Control | 1994 |
Biological approaches to treatment-resistant obsessive compulsive disorder.
Topics: Behavior Therapy; Buspirone; Clonazepam; Combined Modality Therapy; Decision Trees; Drug Therapy, Co | 1993 |
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Cos | 1996 |
New developments in the treatment of obsessive-compulsive disorder.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Age Factors; Age of Onset; Antidepressive Agents, Second- | 1997 |
6 trials available for clonazepam and Anankastic Personality
| Article | Year |
|---|---|
Is quetiapine effective for obsessive and compulsive symptoms in patients with bipolar disorder? A randomized, double-blind, placebo-controlled clinical trial.
Topics: Bipolar Disorder; Clonazepam; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Obses | 2022 |
Topiramate as an adjuvant treatment for obsessive compulsive symptoms in patients with bipolar disorder: a randomized double blind placebo controlled clinical trial.
Topics: Adult; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clonazepam; Double-Blind Method; Drug Th | 2014 |
Memantine as an Adjuvant Treatment for Obsessive Compulsive Symptoms in Manic Phase of Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Topics: Adjuvants, Pharmaceutic; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Dis | 2017 |
A double-blind, placebo-controlled trial of clonazepam in obsessive-compulsive disorder.
Topics: Adult; Aged; Anticonvulsants; Clonazepam; Cognitive Behavioral Therapy; Double-Blind Method; Female; | 2003 |
Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Anxiety; Clomipramine; Clonazepam; Clonidine; Depression; Double-Blind | 1992 |
Clonazepam treatment of obsessions and compulsions.
Topics: Adult; Clinical Trials as Topic; Clonazepam; Female; Follow-Up Studies; Humans; Obsessive-Compulsive | 1990 |
18 other studies available for clonazepam and Anankastic Personality
| Article | Year |
|---|---|
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales.
Topics: Antipsychotic Agents; Benzodiazepines; Clonazepam; Clozapine; Humans; Obsessive-Compulsive Disorder | 2023 |
Alcohol binge drinking in OCD: A compulsive ritualistic behaviour to counter magical thinking.
Topics: Adult; Antipsychotic Agents; Binge Drinking; Ceremonial Behavior; Clonazepam; Cognitive Behavioral T | 2017 |
Obsession of pregnancy: Does it exist?
Topics: Attitude to Health; Citalopram; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Depressive D | 2017 |
Therapeutic challenges in comorbid obsessive compulsive disorder with substance use.
Topics: Adrenergic alpha-2 Receptor Agonists; Clonazepam; Clonidine; Combined Modality Therapy; Fluoxetine; | 2018 |
Treatment of internet addiction in patient with panic disorder and obsessive compulsive disorder: a case report.
Topics: Behavior, Addictive; Clonazepam; Cognitive Behavioral Therapy; Female; Humans; Internet; Obsessive-C | 2015 |
[The Usefulness of Clonazepam as an Augmentative Treatment in a Case of Severe Childhood Onset Obsessive-Compulsive Disorder].
Topics: Adolescent; Benzodiazepines; Clonazepam; Drug Therapy, Combination; Female; GABA Modulators; Humans; | 2015 |
[A Case with Multiple Comorbidities of Obsessive-Compulsive and Related Disorders].
Topics: Adult; Antipsychotic Agents; Aripiprazole; Body Dysmorphic Disorders; Clonazepam; Combined Modality | 2015 |
Treatment-resistant self-mutilation, tics, and obsessive-compulsive disorder in neuroacanthocytosis: a mouth guard as a therapeutic approach.
Topics: Adult; Antipsychotic Agents; Atrophy; Caudate Nucleus; Clonazepam; Clozapine; Dibenzothiazepines; El | 2008 |
Shared obsessive-compulsive disorder: broadening the concept of shared psychotic disorder.
Topics: Citalopram; Clonazepam; Female; GABA Modulators; Humans; Male; Obsessive-Compulsive Disorder; Select | 2010 |
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Topics: Adult; Clonazepam; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Fructose; GABA Modu | 2011 |
Raynaud’s phenomenon in a patient with schizophrenia and obsessive-compulsive disorder: a case report.
Topics: Amlodipine; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clonaze | 2011 |
[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear].
Topics: Adult; Anxiety Disorders; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Combined Modality | 2002 |
Pica responding to SSRI: an OCD spectrum disorder?
Topics: Adult; Anticonvulsants; Citalopram; Clonazepam; Drug Therapy, Combination; Female; Humans; Obsessive | 2009 |
Ziprasidone-associated mania in a case of obssessive-compulsive disorder.
Topics: Anticonvulsants; Bipolar Disorder; Citalopram; Clonazepam; Dose-Response Relationship, Drug; Drug In | 2007 |
Clonazepam for OCD.
Topics: Adolescent; Clonazepam; Humans; Male; Obsessive-Compulsive Disorder; Social Environment | 1993 |
Urinary retention with sertraline, haloperidol, and clonazepam combination.
Topics: Adult; Antipsychotic Agents; Clonazepam; Comorbidity; Constipation; Delusions; Drug Therapy, Combina | 1998 |
Clonazepam treatment of obsessive compulsive disorder.
Topics: Clonazepam; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder | 1990 |
Clonazepam in the treatment of obsessive compulsive disorder associated with panic disorder in one patient.
Topics: Adult; Anxiety Disorders; Clonazepam; Fear; Humans; Lorazepam; Male; Obsessive-Compulsive Disorder; | 1989 |