clonazepam has been researched along with Alzheimer Disease in 6 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Excerpt | Relevance | Reference |
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"We report the case of an 88-year-old man with Alzheimer's disease (AD) of 8 years duration (emerging shortly after the de novo onset of sleeptalking) who developed REM sleep behavior disorder (RBD) after increasing the nightly dose of rivastigmine, an acetylcholinesterase inhibitor, from 1." | 7.76 | Rivastigmine-induced REM sleep behavior disorder (RBD) in a 88-year-old man with Alzheimer's disease. ( Schenck, CH; Yeh, PY; Yeh, SB, 2010) |
"We report the case of an 88-year-old man with Alzheimer's disease (AD) of 8 years duration (emerging shortly after the de novo onset of sleeptalking) who developed REM sleep behavior disorder (RBD) after increasing the nightly dose of rivastigmine, an acetylcholinesterase inhibitor, from 1." | 3.76 | Rivastigmine-induced REM sleep behavior disorder (RBD) in a 88-year-old man with Alzheimer's disease. ( Schenck, CH; Yeh, PY; Yeh, SB, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (33.33) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors | Studies |
---|---|
Ferreira, TR | 1 |
Lopes, LC | 1 |
Motter, FR | 1 |
de Cássia Bergamaschi, C | 1 |
Lauterbach, EC | 1 |
Victoroff, J | 1 |
Coburn, KL | 1 |
Shillcutt, SD | 1 |
Doonan, SM | 1 |
Mendez, MF | 1 |
Yeh, SB | 1 |
Yeh, PY | 1 |
Schenck, CH | 1 |
Grad, R | 1 |
Segal, B | 1 |
Lloyd, GK | 1 |
Lowenthal, A | 1 |
Javoy-Agid, F | 1 |
Constantidinis, J | 1 |
Ginsburg, ML | 1 |
1 review available for clonazepam and Alzheimer Disease
Article | Year |
---|---|
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Benzodiazepines; Benzo | 2010 |
5 other studies available for clonazepam and Alzheimer Disease
Article | Year |
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Potentially inappropriate prescriptions to Brazilian older people with Alzheimer disease: A cross-sectional study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspirin; Brazil; Cardiovascular Agents; Central Nervous | 2021 |
Rivastigmine-induced REM sleep behavior disorder (RBD) in a 88-year-old man with Alzheimer's disease.
Topics: Aged, 80 and over; Alzheimer Disease; Anticonvulsants; Cholinesterase Inhibitors; Clonazepam; Dose-R | 2010 |
Case report: unexplained syncope explained.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anticonvulsants; Clonazepam; Female; Humans; Hypertensio | 2001 |
GABAA receptor complex function in frontal cortex membranes from control and neurological patients.
Topics: Adult; Aged; Alzheimer Disease; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; | 1991 |
Clonazepam for agitated patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1991 |