clonazepam has been researched along with Agranulocytosis in 1 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case suggests that rufinamide may induce the potentially serious adverse effect of agranulocytosis." | 3.81 | A granulocytosis associated with rufinamide: A case report. ( Awaya, T; Heike, T; Ide, M; Kato, T; Nakata, M; Saito, K; Yoshida, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ide, M | 1 |
| Kato, T | 1 |
| Nakata, M | 1 |
| Saito, K | 1 |
| Yoshida, T | 1 |
| Awaya, T | 1 |
| Heike, T | 1 |
1 other study available for clonazepam and Agranulocytosis
| Article | Year |
|---|---|
A granulocytosis associated with rufinamide: A case report.
Topics: Agranulocytosis; Anticonvulsants; Child; Clonazepam; Epilepsy; Humans; Male; Triazoles; Valproic Aci | 2015 |