clonazepam has been researched along with Adverse Drug Event in 4 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we report on a case of a 70-year-old Caucasian female with insomnia and difficulty weaning off long-term use of clonazepam suggesting that a slow acetylator phenotype contributing to patient's presentation." | 1.51 | Prolonged clonazepam-induced withdrawal symptoms in an NAT2 ultraslow acetylator. ( Gupta, SV; Ho, TT; Sanchez-Valle, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Setlakwe, EL | 1 |
| Johnson, AL | 1 |
| Andrade, PHS | 1 |
| Lobo, IMF | 1 |
| da Silva, WB | 1 |
| Ho, TT | 1 |
| Gupta, SV | 1 |
| Sanchez-Valle, A | 1 |
4 other studies available for clonazepam and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Acute encephalopathy in a 2-year-old pot-bellied pig following accidental intoxication with clonazepam.
Topics: Acute Febrile Encephalopathy; Animals; Antidotes; Clonazepam; Diagnosis, Differential; Drug-Related | 2017 |
Risk factors for adverse drug reactions in pediatric inpatients: A cohort study.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Anesthesia, General; Anti-Bacterial Agents; Ant | 2017 |
Prolonged clonazepam-induced withdrawal symptoms in an NAT2 ultraslow acetylator.
Topics: Acetylation; Aged; Arylamine N-Acetyltransferase; Clonazepam; Cytochrome P-450 CYP3A; Drug-Related S | 2019 |