clonazepam has been researched along with Acute Liver Injury, Drug-Induced in 7 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 5.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| "Acetaminophen is a widely used analgesic that can cause acute liver failure when consumed above a maximum daily dose." | 1.35 | Acetaminophen toxicity with concomitant use of carbamazepine. ( Ahmed, SN; Heino, A; Jickling, G, 2009) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 1.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Jickling, G | 1 |
| Heino, A | 1 |
| Ahmed, SN | 1 |
| Keränen, T | 1 |
| Sivenius, J | 1 |
| Friedenberg, FK | 1 |
| Rothstein, KD | 1 |
| Serra-Mestres, J | 1 |
| Shapleske, J | 1 |
| Tym, E | 1 |
| Olsson, R | 1 |
| Zettergren, L | 1 |
1 review available for clonazepam and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
6 other studies available for clonazepam and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Acetaminophen toxicity with concomitant use of carbamazepine.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Back Pain; Carbamazepine; Chemical | 2009 |
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li | 1983 |
Hepatitis secondary to fluoxetine treatment.
Topics: Adult; Anxiety Disorders; Chemical and Drug Induced Liver Injury; Clonazepam; Drug Therapy, Combinat | 1996 |
Treatment of palilalia with trazodone.
Topics: Adult; Anxiety Disorders; Chemical and Drug Induced Liver Injury; Clonazepam; Drug Therapy, Combinat | 1996 |
Anticonvulsant-induced liver damage.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Clonazepam; Humans; L | 1988 |