clonazepam has been researched along with Acute Disease in 32 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Haloperidol was stopped and intravenous clonazepam 5mg/kg was begun." | 5.36 | [Catatonia in a 14 year-old girl: treatment with clorazepam and carbamazepine, a 10-year follow-up]. ( Askenazy, F; Benoit, M; Dor, E; Dupuis, G; Myquel, M; Seddiki, Y; Serret, S, 2010) |
| "Topiramate is a novel anticonvulsant agent with a broad spectrum mechanism of action, and recent clinical reports indicate that it may have mood stabilizing properties in bipolar disorder." | 3.71 | Topiramate as a mood stabilizer. ( Kasper, S; Letmaier, M; Schreinzer, D; Wolf, R, 2001) |
| " She was given 25 mg of intramuscular diphenhydramine and 1 mg of intramuscular benztropine mesylate, which resulted in little relief; however, 1 mg clonazepam caused both the myoclonic jerks and dystonias to resolve completely." | 3.67 | Acute generalized myoclonus following buspirone administration. ( Bridenbaugh, RH; Jabbari, B; Ritchie, EC, 1988) |
| "Chlorpromazine was found to be significantly better than remoxipride on the dropout rate due to inefficacy, Clinical Global Impression (CGI) of severity of illness and Brief Psychiatric Rating Scale (BPRS)." | 2.67 | A placebo-controlled clinical trial of remoxipride and chlorpromazine in newly admitted schizophrenic patients with acute exacerbation. ( Chouinard, G, 1990) |
| "Treatment with lorazepam produced marked improvement in symptomatology, while treatment with clonazepam failed to demonstrate a significant therapeutic effect." | 2.67 | Double-blind comparison of the effects of clonazepam and lorazepam in acute mania. ( Bradwejn, J; Koszycki, D; Meterissian, G; Shriqui, C, 1990) |
| "Clonazepam was found to be significantly more efficacious than lithium in reducing manic symptoms despite the fact that during clonazepam treatment less patients required PRNs of haloperidol." | 2.65 | Antimanic effect of clonazepam. ( Annable, L; Chouinard, G; Young, SN, 1983) |
| " Eighty-two percent (39) of the patients rated clonazepam as being "better" than alprazolam due to decreased dosing frequency and lack of interdose anxiety." | 2.37 | Rebound anxiety in panic disorder patients treated with shorter-acting benzodiazepines. ( Brotman, AW; Herman, JB; Rosenbaum, JF, 1987) |
| "Haloperidol was stopped and intravenous clonazepam 5mg/kg was begun." | 1.36 | [Catatonia in a 14 year-old girl: treatment with clorazepam and carbamazepine, a 10-year follow-up]. ( Askenazy, F; Benoit, M; Dor, E; Dupuis, G; Myquel, M; Seddiki, Y; Serret, S, 2010) |
| "Clonazepam wafers are an effective acute therapy for prolonged seizures." | 1.36 | Dissolving oral clonazepam wafers in the acute treatment of prolonged seizures. ( Hastriter, EV; Ng, YT; Troester, MM, 2010) |
| "A link between cancer and limbic encephalitis (LE) has been proposed." | 1.35 | Acute limbic encephalitis: diagnostic and management implications. ( Baxi, S; Lucas-Ramadan, T; Velamoor, R, 2008) |
| "One patient died of pulmonary edema and subsequent heart failure, but the rest of the patients recovered without any sequelae." | 1.34 | Hemoperfusion in the treatment of acute clozapine intoxication in China. ( Cai, ZJ; He, JL; Li, WB; Ungvari, GS; Xiang, YT, 2007) |
| "Clonazepam was administered orally to 11 newly admitted inpatients." | 1.29 | Clonazepam in acute mania: time-blind evaluation of clinical response and concentrations in plasma. ( Alric, R; Barbe, A; Bottaï, T; Hillaire-Buys, D; Hüe, B; Petit, P; Pouget, R, 1995) |
| "Clonazepam is a potent, long-acting benzodiazepine approved for use in myoclonic and petit mal seizures." | 1.28 | Mania associated with clonazepam. ( Dorevitch, A, 1991) |
| "Clonazepam treatment led to a decrease in agitation and logorrhea, without the side effects associated with neuroleptics." | 1.27 | Use of clonazepam in mania and schizoaffective disorders. ( Bell, IR; Binder, RL; Link, NA; Victor, BS, 1984) |
| "Action myoclonus secondary to posthypoxic encephalopathy is being seen increasingly with improved resuscitation techniques." | 1.26 | Action myoclonus following acute cerebral anoxia. ( DeLisa, JA; Stolov, WC; Troupin, AS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (31.25) | 18.7374 |
| 1990's | 8 (25.00) | 18.2507 |
| 2000's | 9 (28.13) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, RA | 1 |
| Hallahan, B | 1 |
| Tojima, M | 1 |
| Hitomi, T | 1 |
| Jingami, N | 1 |
| Tanioka, K | 1 |
| Yamakado, H | 1 |
| Matsumoto, R | 1 |
| Takahashi, Y | 1 |
| Ikeda, A | 1 |
| Takahashi, R | 1 |
| Sharawat, IK | 1 |
| Dawman, L | 1 |
| Sakata, O | 1 |
| Onishi, H | 1 |
| Machida, Y | 1 |
| Askenazy, F | 1 |
| Dor, E | 1 |
| Benoit, M | 1 |
| Dupuis, G | 1 |
| Serret, S | 1 |
| Myquel, M | 1 |
| Seddiki, Y | 1 |
| Troester, MM | 1 |
| Hastriter, EV | 1 |
| Ng, YT | 1 |
| Wheless, JW | 1 |
| Kleopa, KA | 1 |
| Kyriakides, T | 1 |
| von Wrede, R | 1 |
| He, JL | 1 |
| Xiang, YT | 1 |
| Li, WB | 1 |
| Cai, ZJ | 1 |
| Ungvari, GS | 1 |
| Lucas-Ramadan, T | 1 |
| Baxi, S | 1 |
| Velamoor, R | 1 |
| Chouinard, G | 4 |
| Young, SN | 1 |
| Annable, L | 1 |
| Victor, BS | 1 |
| Link, NA | 1 |
| Binder, RL | 1 |
| Bell, IR | 1 |
| Avanzini, G | 1 |
| Franceschetti, S | 1 |
| Lombardi, B | 1 |
| Passerini, A | 1 |
| Erer, B | 1 |
| Polchi, P | 1 |
| Lucarelli, G | 1 |
| Angelucci, E | 1 |
| Baronciani, D | 1 |
| Galimberti, M | 1 |
| Giardini, C | 1 |
| Gaziev, D | 1 |
| Maiello, A | 1 |
| Bottaï, T | 1 |
| Hüe, B | 1 |
| Hillaire-Buys, D | 1 |
| Barbe, A | 1 |
| Alric, R | 1 |
| Pouget, R | 1 |
| Petit, P | 1 |
| Gomez, R | 1 |
| Huber, J | 1 |
| Tombini, G | 1 |
| Barros, HM | 1 |
| Kumar, R | 1 |
| Letmaier, M | 1 |
| Schreinzer, D | 1 |
| Wolf, R | 1 |
| Kasper, S | 1 |
| Larson, AW | 1 |
| Wasserstrom, WR | 1 |
| Felsher, BF | 1 |
| Chih, JC | 1 |
| DeLisa, JA | 1 |
| Stolov, WC | 1 |
| Troupin, AS | 1 |
| Meloni, G | 1 |
| Raucci, U | 1 |
| Pinto, RM | 1 |
| Spalice, A | 1 |
| Vignetti, M | 1 |
| Iannetti, P | 1 |
| Dorevitch, A | 1 |
| Sachs, GS | 1 |
| Bradwejn, J | 1 |
| Shriqui, C | 1 |
| Koszycki, D | 1 |
| Meterissian, G | 1 |
| Budman, CL | 1 |
| Vandersall, TA | 1 |
| Herman, JB | 1 |
| Brotman, AW | 1 |
| Rosenbaum, JF | 1 |
| Dubin, WR | 1 |
| Ritchie, EC | 1 |
| Bridenbaugh, RH | 1 |
| Jabbari, B | 1 |
4 reviews available for clonazepam and Acute Disease
| Article | Year |
|---|---|
Acute management of seizures in the syndromes of idiopathic generalized epilepsies.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Clonazepam; Comorbidity; Drug Administration Sche | 2003 |
Rebound anxiety in panic disorder patients treated with shorter-acting benzodiazepines.
Topics: Acute Disease; Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Clonazepam; Fear; Female; | 1987 |
Rapid tranquilization: antipsychotics or benzodiazepines?
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Clonazepam; Drug Therapy, Combination; Humans; | 1988 |
Clonazepam in acute and maintenance treatment of bipolar affective disorder.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Double-Blind Method; D | 1987 |
5 trials available for clonazepam and Acute Disease
| Article | Year |
|---|---|
Antimanic effect of clonazepam.
Topics: Acute Disease; Adult; Affective Disorders, Psychotic; Benzodiazepinones; Bipolar Disorder; Clonazepa | 1983 |
A placebo-controlled clinical trial of remoxipride and chlorpromazine in newly admitted schizophrenic patients with acute exacerbation.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Chlorpromazine; Clonazepam; Dose | 1990 |
Double-blind comparison of the effects of clonazepam and lorazepam in acute mania.
Topics: Acute Disease; Adult; Bipolar Disorder; Clonazepam; Double-Blind Method; Drug Therapy, Combination; | 1990 |
The use of benzodiazepines in the treatment of manic-depressive illness.
Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Basal Ga | 1988 |
Clonazepam in acute and maintenance treatment of bipolar affective disorder.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Double-Blind Method; D | 1987 |
24 other studies available for clonazepam and Acute Disease
| Article | Year |
|---|---|
Psychosis improved dysphonia.
Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Clonazepam; Diagnosis, Differential | 2013 |
[Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody].
Topics: Acute Disease; Adult; Autoantibodies; Autoimmunity; Biomarkers; Clonazepam; Drug Therapy, Combinatio | 2014 |
Acute Focal Dystonia After a Single Dose of Oral Cetirizine in a 9-Year-Old Boy.
Topics: Acute Disease; Anti-Allergic Agents; Anticonvulsants; Cetirizine; Child; Clonazepam; Dystonic Disord | 2019 |
Clonazepam oral droplets for the treatment of acute epileptic seizures.
Topics: Acute Disease; Administration, Oral; Animals; Anticonvulsants; Clonazepam; Epilepsy; Intestinal Abso | 2008 |
[Catatonia in a 14 year-old girl: treatment with clorazepam and carbamazepine, a 10-year follow-up].
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Cataplexy; C | 2010 |
Dissolving oral clonazepam wafers in the acute treatment of prolonged seizures.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, | 2010 |
A novel movement disorder of the lower lip.
Topics: Acute Disease; Adult; Anticonvulsants; Botulinum Toxins, Type A; Clonazepam; Female; Humans; Lip; Ma | 2004 |
[Epilepsy: which therapy in acute care?].
Topics: Acute Disease; Anticonvulsants; Benzodiazepines; Clobazam; Clonazepam; Diazepam; Epilepsy; Humans; L | 2006 |
Hemoperfusion in the treatment of acute clozapine intoxication in China.
Topics: Acute Disease; Adult; Alprazolam; Antipsychotic Agents; China; Clonazepam; Clozapine; Depressive Dis | 2007 |
Acute limbic encephalitis: diagnostic and management implications.
Topics: Acute Disease; Antipsychotic Agents; Clonazepam; Confusion; Delirium; Electroencephalography; Humans | 2008 |
Use of clonazepam in mania and schizoaffective disorders.
Topics: Acute Disease; Adult; Benzodiazepinones; Bipolar Disorder; Clonazepam; Drug Administration Schedule; | 1984 |
Segmental action and stimuli-sensitive myoclonus with acute onset. A case report.
Topics: 5-Hydroxytryptophan; Acute Disease; Adult; Angiography; Carbidopa; Carotid Arteries; Cerebrovascular | 1980 |
CsA-associated neurotoxicity and ineffective prophylaxis with clonazepam in patients transplanted for thalassemia major: analysis of risk factors.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; beta-Thalassemia; Blood | 1996 |
Clonazepam in acute mania: time-blind evaluation of clinical response and concentrations in plasma.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Clonazepam; Dose-Respons | 1995 |
Acute effect of different antidepressants on glycemia in diabetic and non-diabetic rats.
Topics: Acute Disease; Analysis of Variance; Animals; Antidepressive Agents; Blood Glucose; Clonazepam; Diab | 2001 |
Acute severe catatonia in a young woman with chronic schizophrenia responding to parenteral clonazepam.
Topics: Acute Disease; Adult; Benzodiazepines; Clonazepam; Drug Therapy, Combination; Female; Humans; Inject | 2001 |
Topiramate as a mood stabilizer.
Topics: Acute Disease; Adaptation, Psychological; Adult; Antimanic Agents; Bipolar Disorder; Clonazepam; Dos | 2001 |
Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.
Topics: Acute Disease; Adult; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy, Post-Traumatic; Humans | 1978 |
Action myoclonus following acute cerebral anoxia.
Topics: Acute Disease; Clonazepam; Humans; Hypoxia, Brain; Male; Middle Aged; Myoclonus; Serotonin | 1979 |
Pretransplant conditioning with busulfan and cyclophosphamide in acute leukemia patients: neurological and electroencephalographic prospective study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Barbiturates; Bone | 1992 |
Mania associated with clonazepam.
Topics: Acute Disease; Adult; Bipolar Disorder; Chronic Disease; Clonazepam; Humans; Male; Schizophrenia | 1991 |
Use of clonazepam for bipolar affective disorder.
Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Drug Therapy, Combination; | 1990 |
Clonazepam treatment of acute mania in an AIDS patient.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Bipolar Disorder; Clonazepam; Female; Huma | 1990 |
Acute generalized myoclonus following buspirone administration.
Topics: Acute Disease; Akathisia, Drug-Induced; Anxiety Disorders; Buspirone; Clonazepam; Depressive Disorde | 1988 |