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clonazepam and Acathisia, Drug-Induced

clonazepam has been researched along with Acathisia, Drug-Induced in 15 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Research Excerpts

ExcerptRelevanceReference
"This randomized, parallel-group, open study investigated the efficacy and safety of risperidone oral solution (RIS-OS) in combination with clonazepam and intramuscular haloperidol for the treatment of acute agitation in patients with schizophrenia, and the study explored the possibility of decreasing the efficacy of an acute 6-week treatment by switching intramuscular haloperidol injection to RIS-OS."9.16Comparison of risperidone oral solution and intramuscular haloperidol with the latter shifting to oral therapy for the treatment of acute agitation in patients with schizophrenia. ( Chen, H; Fang, M; Huang, J; Li, LH; Li, Y; Liu, L; Wang, B; Wang, G; Wu, R; Ye, M; Zhang, L; Zhang, Q; Zhao, JP; Zheng, H; Zhou, J; Zhu, S, 2012)
"This randomized, parallel-group, open study investigated the efficacy and safety of risperidone oral solution (RIS-OS) in combination with clonazepam and intramuscular haloperidol for the treatment of acute agitation in patients with schizophrenia, and the study explored the possibility of decreasing the efficacy of an acute 6-week treatment by switching intramuscular haloperidol injection to RIS-OS."5.16Comparison of risperidone oral solution and intramuscular haloperidol with the latter shifting to oral therapy for the treatment of acute agitation in patients with schizophrenia. ( Chen, H; Fang, M; Huang, J; Li, LH; Li, Y; Liu, L; Wang, B; Wang, G; Wu, R; Ye, M; Zhang, L; Zhang, Q; Zhao, JP; Zheng, H; Zhou, J; Zhu, S, 2012)
"Olanzapine is a safely and comprehensively applicable atypical antipsychotic drug, for the treatment of schizophrenia, and of the mild to sever maniac episode."3.73[Akathisia in the course of olanzapine treatment]. ( Csonka, A; Makkos, Z, 2006)
"Eighteen patients with restless legs syndrome (RLS) and 4 patients with neuroleptic-induced akathisia (NIA) underwent all-night polysomnographic recordings before and during clonazepam treatment."3.69A polysomnographic study on periodic limb movements in patients with restless legs syndrome and neuroleptic-induced akathisia. ( Horiguchi, J; Inami, Y; Katagiri, H; Nishimatsu, O; Sasaki, A; Sukegawa, T; Yamawaki, S, 1997)
" She was given 25 mg of intramuscular diphenhydramine and 1 mg of intramuscular benztropine mesylate, which resulted in little relief; however, 1 mg clonazepam caused both the myoclonic jerks and dystonias to resolve completely."3.67Acute generalized myoclonus following buspirone administration. ( Bridenbaugh, RH; Jabbari, B; Ritchie, EC, 1988)
"Clonazepam, which is a benzodiazepine structurally related to chlordiazepoxide hydrochloride, diazepam and nitrazepam, has been available for the treatment of seizure disorders in the USA since 1976 and in Japan since 1981."1.30Clonazepam as a therapeutic adjunct to improve the management of psychiatric disorders. ( Aoki, S; Morishita, S; Watanabe, S, 1998)
"A patient with neuroleptic-induced akathisia was successfully treated with a combination of baclofen (a GABA agonist) and clonazepam (a serotonergic agent)."1.27Successful treatment of neuroleptic-induced akathisia with baclofen and clonazepam. A case report. ( Sandyk, R, 1985)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's7 (46.67)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fang, M1
Chen, H1
Li, LH1
Wu, R1
Li, Y1
Liu, L1
Ye, M1
Huang, J1
Zhu, S1
Wang, G1
Zhang, Q1
Zheng, H1
Zhang, L1
Wang, B1
Zhou, J1
Zhao, JP1
Makkos, Z1
Csonka, A1
Adler, LA2
Angrist, BM1
Eberstein, S1
Angrist, B1
Pujalte, D1
Bottaï, T1
Huë, B1
Alric, R1
Pouget, R1
Blayac, JP1
Petit, P1
Inami, Y3
Horiguchi, J4
Nishimatsu, O4
Sasaki, A2
Sukegawa, T2
Katagiri, H1
Yamawaki, S1
Morishita, S1
Aoki, S1
Watanabe, S1
Barfod, S1
Wendelboe, J1
Kutcher, S1
Williamson, P1
MacKenzie, S2
Marton, P1
Ehrlich, M1
Kutcher, SP1
Galarraga, W1
Szalai, J1
Ritchie, EC1
Bridenbaugh, RH1
Jabbari, B1
Sandyk, R1

Trials

6 trials available for clonazepam and Acathisia, Drug-Induced

ArticleYear
Comparison of risperidone oral solution and intramuscular haloperidol with the latter shifting to oral therapy for the treatment of acute agitation in patients with schizophrenia.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:2

    Topics: Administration, Oral; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; China; Clonazepam; Diagn

2012
A double-blind comparison of clonazepam and placebo in the treatment of neuroleptic-induced akathisia.
    Clinical neuropharmacology, 1994, Volume: 17, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Anticonvulsants; Antipsychotic Agents; Clonazepam; Dose-Response Rel

1994
Periodic limb movement disorder in neuroleptic-induced akathisia.
    The Kobe journal of medical sciences, 1997, Volume: 43, Issue:5

    Topics: Adult; Akathisia, Drug-Induced; Anticonvulsants; Antipsychotic Agents; Clonazepam; Electromyography;

1997
Usefulness of antiparkinsonian drugs during neuroleptic treatment and the effect of clonazepam on akathisia and parkinsonism occurred after antiparkinsonian drug withdrawal: a double-blind study.
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:3

    Topics: Akathisia, Drug-Induced; Antiparkinson Agents; Antipsychotic Agents; Chronic Disease; Clonazepam; Do

1992
Successful clonazepam treatment of neuroleptic-induced akathisia in older adolescents and young adults: a double-blind, placebo-controlled study.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Doub

1989
Clonazepam treatment of adolescents with neuroleptic-induced akathisia.
    The American journal of psychiatry, 1987, Volume: 144, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Tri

1987

Other Studies

9 other studies available for clonazepam and Acathisia, Drug-Induced

ArticleYear
[Akathisia in the course of olanzapine treatment].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2006, Volume: 8, Issue:4

    Topics: Aged; Akathisia, Drug-Induced; Anticonvulsants; Antipsychotic Agents; Azabicyclo Compounds; Benzodia

2006
Paroxetine and akathisia.
    Biological psychiatry, 1995, Mar-01, Volume: 37, Issue:5

    Topics: Akathisia, Drug-Induced; Clonazepam; Depressive Disorder; Dose-Response Relationship, Drug; Drug Adm

1995
Nefazodone and akathisia.
    Biological psychiatry, 1996, Oct-15, Volume: 40, Issue:8

    Topics: Akathisia, Drug-Induced; Antidepressive Agents, Second-Generation; Clonazepam; Depressive Disorder;

1996
A polysomnographic study on periodic limb movements in patients with restless legs syndrome and neuroleptic-induced akathisia.
    Hiroshima journal of medical sciences, 1997, Volume: 46, Issue:4

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Anticonvulsants; Antipsychotic Agents; Case-Contro

1997
Clonazepam as a therapeutic adjunct to improve the management of psychiatric disorders.
    Psychiatry and clinical neurosciences, 1998, Volume: 52, Issue:1

    Topics: Adult; Aged; Akathisia, Drug-Induced; Anticonvulsants; Bipolar Disorder; Clonazepam; Delusions; Depr

1998
[Severe psychiatric side effects of clonazepam treatment. 2 cases].
    Ugeskrift for laeger, 1977, Oct-10, Volume: 139, Issue:41

    Topics: Adolescent; Aggression; Akathisia, Drug-Induced; Benzodiazepinones; Child, Preschool; Clonazepam; Fe

1977
Successful treatment with clonazepam for neuroleptic-induced akathisia.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:1

    Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clonazepam; Female; Humans; Male;

1989
Acute generalized myoclonus following buspirone administration.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:6

    Topics: Acute Disease; Akathisia, Drug-Induced; Anxiety Disorders; Buspirone; Clonazepam; Depressive Disorde

1988
Successful treatment of neuroleptic-induced akathisia with baclofen and clonazepam. A case report.
    European neurology, 1985, Volume: 24, Issue:4

    Topics: Akathisia, Drug-Induced; Baclofen; Benzodiazepinones; Clonazepam; Haloperidol; Humans; Male; Middle

1985