clonazepam has been researched along with Abnormalities, Drug-Induced in 6 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 7.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| "Clonazepam (Klonopin) is a benzodiazepine that has been used widely to treat seizures and conditions such as panic attacks and anxiety disorder." | 5.32 | Clonazepam use in pregnancy and the risk of malformations. ( Franz, A; Holmes, LB; Houde, K; Lin, AE; Peller, AJ; Westgate, MN, 2004) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 5.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 3.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| "Clonazepam (Klonopin) is a benzodiazepine that has been used widely to treat seizures and conditions such as panic attacks and anxiety disorder." | 1.32 | Clonazepam use in pregnancy and the risk of malformations. ( Franz, A; Holmes, LB; Houde, K; Lin, AE; Peller, AJ; Westgate, MN, 2004) |
| "Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 1.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, AE | 1 |
| Peller, AJ | 1 |
| Westgate, MN | 1 |
| Houde, K | 1 |
| Franz, A | 1 |
| Holmes, LB | 1 |
| Saito, H | 1 |
| Kobayashi, H | 1 |
| Takeno, S | 1 |
| Sakai, T | 1 |
| Keränen, T | 1 |
| Sivenius, J | 1 |
| Eros, E | 1 |
| Czeizel, AE | 1 |
| Rockenbauer, M | 1 |
| Sorensen, HT | 1 |
| Olsen, J | 1 |
| Sullivan, FM | 1 |
| McElhatton, PR | 1 |
| Calabrese, JR | 1 |
| Gulledge, AD | 1 |
6 other studies available for clonazepam and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Clonazepam use in pregnancy and the risk of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Clonazepam; Congenital Abnormalities; Female; Humans; | 2004 |
Fetal toxicity of benzodiazepines in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; F | 1984 |
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li | 1983 |
A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Alprazolam; Anti-Anxiety Agents; Antico | 2002 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Fema | 1977 |
Carbamazepine, clonazepam use during pregnancy.
Topics: Abnormalities, Drug-Induced; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy; Female; Humans; | 1986 |