clomipramine has been researched along with Weight Loss in 5 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Weight Loss: Decrease in existing BODY WEIGHT.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the effect of acute stimulation of the corticotropic axis on plasma leptin, the ob gene product, in 7 women of normal weight and 12 women with obesity." | 5.08 | Plasma leptin and acute serotoninergic stimulation of the corticotropic axis in women who are normal weight or obese. ( Basdevant, A; Guy-Grand, B; Laferrère, B; Lahlou, N; Oppert, JM; Roger, M, 1997) |
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| " Using cognitive-behavioural therapy, clomipramine and enteral nutrition, weight gain and disappearance of restrictive and obsessive-compulsive behaviours were obtained." | 3.75 | Obsessive compulsive disorder as a cause of atypical eating disorder: a case report. ( Dechelotte, P; Garcia, FD; Houy-Durand, E; Thibaut, F, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garcia, FD | 1 |
| Houy-Durand, E | 1 |
| Thibaut, F | 1 |
| Dechelotte, P | 1 |
| Laferrère, B | 2 |
| Lahlou, N | 2 |
| Saltiel, H | 1 |
| Roger, M | 2 |
| Basdevant, A | 2 |
| Oppert, JM | 2 |
| Guy-Grand, B | 2 |
| Shioiri, T | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Yamada, N | 1 |
| Takahashi, S | 1 |
| Anderson, I | 1 |
| Cowen, P | 1 |
3 trials available for clomipramine and Weight Loss
| Article | Year |
|---|---|
Hypersensitivity of the corticotropic axis to the serotoninergic agent clomipramine in obese women.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Area Under Curve; Clomipramine; Diet, Reducing; Doub | 1994 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
Plasma leptin and acute serotoninergic stimulation of the corticotropic axis in women who are normal weight or obese.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Body Mass Index; Clomipramine; Double-Blind Method; | 1997 |
2 other studies available for clomipramine and Weight Loss
| Article | Year |
|---|---|
Obsessive compulsive disorder as a cause of atypical eating disorder: a case report.
Topics: Adult; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Clomipramine; Cognitive Behavioral Therap | 2009 |
Neuroendocrine responses to L-tryptophan as an index of brain serotonin function: effect of weight loss.
Topics: Adult; Biological Transport, Active; Brain Chemistry; Clomipramine; Depression; Diet, Reducing; Fema | 1991 |