clomipramine has been researched along with Weight Gain in 7 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term treatment with clomipramine (CMI), a tricyclic antidepressant, induces food craving and body weight gain in patients." | 7.74 | Effect of chronic treatment with clomipramine on food intake, macronutrient selection and body weight gain in rats. ( Calegari, L; Gentil, V; Gorenstein, C; Nunes-de-Souza, RL; Planeta, CS, 2007) |
| " The study evaluated the efficacy of amisulpride, fluoxetine and clomipramine at the beginning of the re-feeding phase of the treatment of restricting anorexia nervosa according to DSM-IV criteria." | 5.09 | A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics. ( Cavagnini, F; Clemente, A; Ferrari, VM; Laini, V; Lugo, F; Mantero, M; Mauri, MC; Redaelli, G; Ruggiero, GM; Zappulli, D, 2001) |
| " Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern." | 5.07 | Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993) |
| " Using cognitive-behavioural therapy, clomipramine and enteral nutrition, weight gain and disappearance of restrictive and obsessive-compulsive behaviours were obtained." | 3.75 | Obsessive compulsive disorder as a cause of atypical eating disorder: a case report. ( Dechelotte, P; Garcia, FD; Houy-Durand, E; Thibaut, F, 2009) |
| "Mirtazapine is a noradrenergic and specific serotonergic antidepressant, characterized by a unique pharmacologic profile, favorable pharmacokinetics, and proven efficacy and safety." | 2.40 | Mirtazapine: clinical advantages in the treatment of depression. ( Burrows, GD; Kremer, CM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garcia, FD | 1 |
| Houy-Durand, E | 1 |
| Thibaut, F | 1 |
| Dechelotte, P | 1 |
| de Souza, SL | 1 |
| Nogueira, MI | 1 |
| de Jesus Deiró, TC | 1 |
| de Castro, FM | 1 |
| da Silva, CM | 1 |
| da Silva, MC | 1 |
| de Lira, LO | 1 |
| Azmitia, EC | 1 |
| de Castro, RM | 1 |
| Maina, G | 1 |
| Albert, U | 1 |
| Salvi, V | 1 |
| Bogetto, F | 1 |
| Calegari, L | 1 |
| Gorenstein, C | 1 |
| Gentil, V | 1 |
| Planeta, CS | 1 |
| Nunes-de-Souza, RL | 1 |
| Shioiri, T | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Yamada, N | 1 |
| Takahashi, S | 1 |
| Burrows, GD | 1 |
| Kremer, CM | 1 |
| Ruggiero, GM | 1 |
| Laini, V | 1 |
| Mauri, MC | 1 |
| Ferrari, VM | 1 |
| Clemente, A | 1 |
| Lugo, F | 1 |
| Mantero, M | 1 |
| Redaelli, G | 1 |
| Zappulli, D | 1 |
| Cavagnini, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Analyses of Mirtazapine in the Treatment of Malignant Tumor Related Depression: A Phase II, Placebo-controlled, Randomized, Double-blinded Clinical Trial in Advanced Non-small Cell Lung Cancer Patients[NCT02650544] | Phase 2 | 236 participants (Anticipated) | Interventional | 2015-12-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clomipramine and Weight Gain
| Article | Year |
|---|---|
Mirtazapine: clinical advantages in the treatment of depression.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine | 1997 |
3 trials available for clomipramine and Weight Gain
| Article | Year |
|---|---|
Weight gain during long-term treatment of obsessive-compulsive disorder: a prospective comparison between serotonin reuptake inhibitors.
Topics: Adult; Ambulatory Care; Citalopram; Clomipramine; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies | 2004 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine | 1993 |
A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics.
Topics: Adult; Amenorrhea; Amisulpride; Anorexia Nervosa; Antidepressive Agents, Second-Generation; Antidepr | 2001 |
3 other studies available for clomipramine and Weight Gain
| Article | Year |
|---|---|
Obsessive compulsive disorder as a cause of atypical eating disorder: a case report.
Topics: Adult; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Clomipramine; Cognitive Behavioral Therap | 2009 |
Differential effects on somatic and reflex development by chronic clomipramine treatment.
Topics: Age Factors; Animals; Animals, Suckling; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipr | 2004 |
Effect of chronic treatment with clomipramine on food intake, macronutrient selection and body weight gain in rats.
Topics: Animals; Body Weight; Clomipramine; Diet; Dietary Carbohydrates; Eating; Food Preferences; Male; Pho | 2007 |