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clomipramine and Syndrome

clomipramine has been researched along with Syndrome in 32 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"The reduction of pain by two antidepressants, clomipramine and mianserin, was, in this study on 253 patients with chronic idiopathic pain syndrome, found to be not better than a placebo when all patients were compared independently of the classification of pain."9.06Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study. ( Bech, P; Hansen, HJ; Langemark, M; Loldrup, D; Olesen, J, 1989)
"In October of 1989, a clustering of cases with eosinophilia lead to the identification of a new syndrome: The eosinophilia myalgia syndrome associated with the use of an L-tryptophan product."7.68Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan. ( Goronzy, JJ; Weyand, CM, 1990)
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."6.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
"The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ."5.30Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997)
"The reduction of pain by two antidepressants, clomipramine and mianserin, was, in this study on 253 patients with chronic idiopathic pain syndrome, found to be not better than a placebo when all patients were compared independently of the classification of pain."5.06Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study. ( Bech, P; Hansen, HJ; Langemark, M; Loldrup, D; Olesen, J, 1989)
"In October of 1989, a clustering of cases with eosinophilia lead to the identification of a new syndrome: The eosinophilia myalgia syndrome associated with the use of an L-tryptophan product."3.68Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan. ( Goronzy, JJ; Weyand, CM, 1990)
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."2.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
"Clomipramine and mianserin were significantly superior to placebo in the topographical pain subgroup with headache using area under the improvement curves as criteria (p less than 0."2.66Discomfort or disability in patients with chronic pain syndrome. ( Bech, P; Hansen, HJ; Langemark, M; Olesen, J; Poulsen, DL, 1987)
"Treatment with clomipramine has been suggested, although most sufferers require only reassurance that the spells are benign in nature."2.41The exploding head syndrome. ( Green, MW, 2001)
"Clomipramine treatment was beneficial."1.34Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome. ( De Bleecker, JL; Hemelsoet, DM, 2007)
"The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ."1.30Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997)
"Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system."1.30Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's22 (68.75)18.2507
2000's3 (9.38)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gama-Marques, J1
Jesus, G1
Brissos, S1
Gallego, J1
Hauss, PA1
Salaün, M1
Picard, D1
Bota, S1
Lachkar, S1
Dominique, S1
Thiberville, L1
Pruidze, MV1
Maloletnev, VI1
Hemelsoet, DM1
De Bleecker, JL1
Meinck, HM1
Ricker, K1
Conrad, B1
Verhoeven, WM1
Noten, JB1
Tuinier, S1
van Schendel, FM1
Power, BM1
Pinder, M1
Hackett, LP1
Ilett, KF1
Serfaty, MA1
McCluskey, S1
Eccleston, D1
Hernandez, AF1
Montero, MN1
Pla, A1
Villanueva, E1
Cano-Muñoz, JL1
Montejo-Iglesias, ML1
Yañez-Saez, RM1
Gálvez-Borrero, IM1
Joseph, MG1
Jouanny, AC1
Chomienne, F1
Champion, G1
Giniès, JL1
Limal, JM1
Nierenberg, DW1
Semprebon, M1
Lejoyeux, M2
Rouillon, F1
Adès, J2
Spigset, O1
Mjörndal, T1
Lövheim, O1
Nijhawan, PK1
Katz, G1
Winter, S1
Gillman, PK2
François, B1
Marquet, P1
Desachy, A1
Roustan, J1
Lachatre, G1
Gastinne, H1
Amsterdam, JD1
García-España, F1
Rosenzweig, M1
Molaie, M1
Ferrer-Dufol, A1
Perez-Aradros, C1
Murillo, EC1
Marques-Alamo, JM1
Finge, T1
Malavialle, C1
Lambert, J1
Dardennes, RM1
Even, C1
Ballon, N1
Bange, F1
Ter Braak, GI1
Green, MW1
Schwartz, BA1
Fineyre, F1
Nisijima, K1
Hirayama, M1
Goronzy, JJ1
Weyand, CM1
Loldrup, D1
Langemark, M2
Hansen, HJ2
Olesen, J2
Bech, P2
Wurthmann, C1
Hartung, HP1
Dengler, W1
Gerhardt, P1
Poulsen, DL1

Reviews

2 reviews available for clomipramine and Syndrome

ArticleYear
[Hypothalamic syndromes. Review of clinical and endocrinal semiology].
    Annales de pediatrie, 1993, Volume: 40, Issue:7

    Topics: Child, Preschool; Clomipramine; Disorders of Excessive Somnolence; Female; Follow-Up Studies; Gonado

1993
The exploding head syndrome.
    Current pain and headache reports, 2001, Volume: 5, Issue:3

    Topics: Clomipramine; Headache; Humans; Perception; Selective Serotonin Reuptake Inhibitors; Syndrome

2001

Trials

4 trials available for clomipramine and Syndrome

ArticleYear
Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arousal; Brain; Clomipramine; Depressive Disorder; Female; Humans; M

1993
Clomipramine augmentation in treatment-resistant depression.
    Depression and anxiety, 1997, Volume: 5, Issue:2

    Topics: Adult; Aged; Akathisia, Drug-Induced; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Sq

1997
Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Clomipramine; Female; Humans; Ma

1989
Discomfort or disability in patients with chronic pain syndrome.
    Psychotherapy and psychosomatics, 1987, Volume: 48, Issue:1-4

    Topics: Clinical Trials as Topic; Clomipramine; Disability Evaluation; Double-Blind Method; Humans; Mianseri

1987

Other Studies

26 other studies available for clomipramine and Syndrome

ArticleYear
[Olfactory reference syndrome and hyperhidrosis: comorbidity in one patient].
    Revista de neurologia, 2014, Dec-16, Volume: 59, Issue:12

    Topics: Adult; Body Dysmorphic Disorders; Clomipramine; Cognitive Behavioral Therapy; Combined Modality Ther

2014
[Clomipramine hypersensitivity with predominantly pulmonary involvement].
    Revue des maladies respiratoires, 2012, Volume: 29, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Drug Eruptions; Drug Hypersensitivity; Female; Human

2012
[Peculiarities of tactics in the treatment of chronic pain syndrome in women].
    Voenno-meditsinskii zhurnal, 2006, Volume: 327, Issue:7

    Topics: Adult; Chronic Disease; Clomipramine; Female; Humans; Menstruation; Middle Aged; Pain; Selective Ser

2006
Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome.
    European journal of neurology, 2007, Volume: 14, Issue:2

    Topics: Body Temperature; Brain Injuries; Clomipramine; Corpus Callosum; Humans; Hypothermia; Magnetic Reson

2007
The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:3

    Topics: Adult; Brain Stem; Clomipramine; Clonidine; Diazepam; Electromyography; Female; Humans; Muscle Rigid

1984
[The serotonin syndrome; a misdiagnosed complication of antidepressive agents].
    Nederlands tijdschrift voor geneeskunde, 1995, Oct-14, Volume: 139, Issue:41

    Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents; Clomipramine; Delirium; Diagnosis, Differenti

1995
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:4

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy

1995
Extreme suicidality following serotonin syndrome.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 167, Issue:3

    Topics: Adolescent; Antidepressive Agents; Clomipramine; Depressive Disorder; Dothiepin; Drug Administration

1995
Fatal moclobemide overdose or death caused by serotonin syndrome?
    Journal of forensic sciences, 1995, Volume: 40, Issue:1

    Topics: Adult; Antidepressive Agents; Benzamides; Cause of Death; Clomipramine; Drug Interactions; Drug Over

1995
Possible serotonin syndrome following the combined administration of clomipramine and alprazolam.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:3

    Topics: Aged; Alprazolam; Clomipramine; Depressive Disorder; Female; Humans; Serotonin; Syndrome

1995
The central nervous system serotonin syndrome.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:1

    Topics: Adult; Central Nervous System; Clomipramine; Depressive Disorder; Dextromethorphan; Drug Interaction

1993
Serotonin syndrome caused by a moclobemide-clomipramine interaction.
    BMJ (Clinical research ed.), 1993, Jan-23, Volume: 306, Issue:6872

    Topics: Aged; Benzamides; Clomipramine; Drug Interactions; Female; Humans; Moclobemide; Monoamine Oxidase In

1993
Psychiatric illness and the serotonin syndrome: an emerging adverse drug effect leading to intensive care unit admission.
    Critical care medicine, 1996, Volume: 24, Issue:6

    Topics: Alcohol Withdrawal Delirium; Buspirone; Clomipramine; Diagnosis, Differential; Drug Therapy, Combina

1996
Successful treatment of serotonin syndrome with chlorpromazine.
    The Medical journal of Australia, 1996, Sep-16, Volume: 165, Issue:6

    Topics: Central Nervous System Diseases; Chlorpromazine; Clomipramine; Depression; Drug Interactions; Humans

1996
Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association.
    Intensive care medicine, 1997, Volume: 23, Issue:1

    Topics: Antidepressive Agents; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female; Humans; M

1997
Serotonin syndrome presenting with migrainelike stroke.
    Headache, 1997, Volume: 37, Issue:8

    Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi

1997
Fatal serotonin syndrome caused by moclobemide-clomipramine overdose.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:1-2

    Topics: Adult; Benzamides; Clomipramine; Clorazepate Dipotassium; Drug Interactions; Drug Overdose; Fatal Ou

1998
Serotonin syndrome--clomipramine too soon after moclobemide?
    International clinical psychopharmacology, 1997, Volume: 12, Issue:6

    Topics: Adult; Benzamides; Central Nervous System Diseases; Clomipramine; Depressive Disorder; Drug Interact

1997
[Fatal form of serotonin syndrome].
    Annales francaises d'anesthesie et de reanimation, 1997, Volume: 16, Issue:1

    Topics: Adult; Benzamides; Clomipramine; Fatal Outcome; Female; Humans; Moclobemide; Monoamine Oxidase Inhib

1997
Serotonin syndrome caused by a clomipramine-moclobemide interaction.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:7

    Topics: Adult; Benzamides; Central Nervous System Diseases; Clomipramine; Confusion; Drug Interactions; Fema

1998
[The hyperglycemic dehydration syndrome].
    Nederlands tijdschrift voor geneeskunde, 1998, Oct-10, Volume: 142, Issue:41

    Topics: Adult; Antidepressive Agents; Benzodiazepines; Clomipramine; Dehydration; Depressive Disorder; Diabe

1998
Letter: Ondine's curse.
    Lancet (London, England), 1976, Sep-25, Volume: 2, Issue:7987

    Topics: Child; Clomipramine; Dibenzazepines; Dyspnea; Humans; Hypoventilation; Syndrome; Tracheotomy

1976
The serotonin syndrome.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Adult; Clomipramine; Depressive Disorder; Humans; Male; Myoclonus; Serotonin; Syndrome

1992
[ICU syndrome].
    Kokyu to junkan. Respiration & circulation, 1991, Volume: 39, Issue:12

    Topics: Aged; Anxiety; Benzodiazepines; Clomipramine; Critical Care; Delirium; Depressive Disorder; Female;

1991
Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan.
    Klinische Wochenschrift, 1990, Jul-17, Volume: 68, Issue:14

    Topics: Adult; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Eosinophilia; Female; Humans; L

1990
[Kleine-Levin syndrome. The provocation of manic symptoms by an antidepressant and a therapeutic trial of carbamazepine].
    Deutsche medizinische Wochenschrift (1946), 1989, Oct-06, Volume: 114, Issue:40

    Topics: Adolescent; Bipolar Disorder; Carbamazepine; Clomipramine; Disorders of Excessive Somnolence; Drug E

1989