clomipramine has been researched along with Sleep Initiation and Maintenance Disorders in 5 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-eight patients with DSM-III-R panic disorder with or without agoraphobia underwent 13 weeks of clomipramine treatment." | 9.08 | Clomipramine treatment of panic disorder: pros and cons. ( Campeas, R; Coplan, JD; Fallon, BA; Fyer, AJ; Gorman, JM; Klein, DF; Leibowitz, MR; Papp, LA; Schneier, FR, 1997) |
| "Differences between the side effect profiles of clomipramine (CMI) and the selective serotonin reuptake inhibitors may be important factors in both treatment outcome and patient selection in obsessive-compulsive disorder (OCD)." | 5.09 | Side effects as predictors of drug response in obsessive-compulsive disorder. ( Ackerman, DL; Bystritsky, A; Greenland, S, 1999) |
| "Fifty-eight patients with DSM-III-R panic disorder with or without agoraphobia underwent 13 weeks of clomipramine treatment." | 5.08 | Clomipramine treatment of panic disorder: pros and cons. ( Campeas, R; Coplan, JD; Fallon, BA; Fyer, AJ; Gorman, JM; Klein, DF; Leibowitz, MR; Papp, LA; Schneier, FR, 1997) |
| "2 patients with withdrawal symptoms following discontinuation of clomipramine are presented." | 1.28 | [Withdrawal reactions after clomipramine]. ( Aizenberg, D; Hermesh, H; Weizman, A; Zemishlany, Z, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeman, CP | 1 |
| Trimble, MR | 1 |
| Deakin, JF | 1 |
| Stokes, TM | 1 |
| Ashford, JJ | 1 |
| Papp, LA | 1 |
| Schneier, FR | 1 |
| Fyer, AJ | 1 |
| Leibowitz, MR | 1 |
| Gorman, JM | 1 |
| Coplan, JD | 1 |
| Campeas, R | 1 |
| Fallon, BA | 1 |
| Klein, DF | 1 |
| Ackerman, DL | 1 |
| Greenland, S | 1 |
| Bystritsky, A | 1 |
| Kielholz, P | 1 |
| Adams, C | 1 |
| Zemishlany, Z | 1 |
| Aizenberg, D | 1 |
| Hermesh, H | 1 |
| Weizman, A | 1 |
3 trials available for clomipramine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Fluvoxamine versus clomipramine in the treatment of obsessive compulsive disorder: a multicenter, randomized, double-blind, parallel group comparison.
Topics: Adult; Ambulatory Care; Clomipramine; Double-Blind Method; Female; Fluvoxamine; Headache; Humans; Ma | 1994 |
Clomipramine treatment of panic disorder: pros and cons.
Topics: Adult; Aged; Agoraphobia; Antidepressive Agents, Tricyclic; Clomipramine; Comorbidity; Drug Administ | 1997 |
Side effects as predictors of drug response in obsessive-compulsive disorder.
Topics: Adolescent; Adult; Anxiety; Clomipramine; Dose-Response Relationship, Drug; Ejaculation; Female; Flu | 1999 |
2 other studies available for clomipramine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
[Diagnosis and treatment of depressive states in everyday practice (author's transl)].
Topics: Adjustment Disorders; Antidepressive Agents; Bipolar Disorder; Clomipramine; Family Practice; Fatigu | 1978 |
[Withdrawal reactions after clomipramine].
Topics: Anxiety; Clomipramine; Fatigue; Female; Headache; Humans; Male; Middle Aged; Sleep Initiation and Ma | 1992 |