clomipramine has been researched along with Serotonin Syndrome in 8 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a patient with a history of clomipramine-induced serotonin syndrome 5 yr prior who developed serotonin syndrome after a single dose of meperidine." | 7.75 | Meperidine-induced serotonin syndrome in a susceptible patient. ( Chien, CC; Guo, SL; Liu, CC; Ng, CC; Sun, HL; Wu, TJ, 2009) |
| "To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen." | 7.71 | Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine. ( Dewan, V; Zerjav-Lacombe, S, 2001) |
| "We present a patient with a history of clomipramine-induced serotonin syndrome 5 yr prior who developed serotonin syndrome after a single dose of meperidine." | 3.75 | Meperidine-induced serotonin syndrome in a susceptible patient. ( Chien, CC; Guo, SL; Liu, CC; Ng, CC; Sun, HL; Wu, TJ, 2009) |
| "To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen." | 3.71 | Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine. ( Dewan, V; Zerjav-Lacombe, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinel-Ríos, FJ | 1 |
| Peñuelas-Calvo, I | 1 |
| Cerezo-Ramírez, N | 1 |
| Hamad-Cueto, O | 1 |
| García-Casares, N | 1 |
| Guo, SL | 1 |
| Wu, TJ | 1 |
| Liu, CC | 1 |
| Ng, CC | 1 |
| Chien, CC | 1 |
| Sun, HL | 1 |
| Héritier Barras, AC | 1 |
| Walder, B | 1 |
| Seeck, M | 1 |
| Brooks, SA | 1 |
| Rosebush, PI | 1 |
| Margetts, P | 1 |
| Mazurek, MF | 1 |
| Nisijima, K | 1 |
| Zerjav-Lacombe, S | 1 |
| Dewan, V | 1 |
| Isbister, GK | 1 |
| Dawson, A | 1 |
| Whyte, IM | 1 |
| Whtye, IM | 1 |
8 other studies available for clomipramine and Serotonin Syndrome
| Article | Year |
|---|---|
Serotonin syndrome induced by a combination of venlafaxine and clomipramine. A case report.
Topics: Antidepressive Agents, Second-Generation; Clomipramine; Drug Therapy, Combination; Humans; Male; Mid | 2016 |
Meperidine-induced serotonin syndrome in a susceptible patient.
Topics: Adult; Analgesics, Opioid; Clomipramine; Humans; Male; Meperidine; Pain, Postoperative; Selective Se | 2009 |
Serotonin syndrome following Methylene Blue infusion: a rare complication of antidepressant therapy.
Topics: Adenoma; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Critical Care; Dantrolene; Drug Inter | 2010 |
The serotonin syndrome as a learning opportunity.
Topics: Adult; Clomipramine; Diagnosis, Differential; Disease Progression; Drug Therapy, Combination; Female | 1998 |
Serotonin syndrome as a result of clomipramine monotherapy.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Female; Humans; Middle Aged; Selective S | 1999 |
Abnormal monoamine metabolism in cerebrospinal fluid in a case of serotonin syndrome.
Topics: Adult; Amoxapine; Biogenic Monoamines; Clomipramine; Depression; Humans; Male; Selective Serotonin R | 2000 |
Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Humans; Male | 2001 |
Comment: serotonin syndrome and 5-HT2A antagonism.
Topics: Animals; Clomipramine; Clozapine; Humans; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selecti | 2001 |