clomipramine has been researched along with Pyrexia in 6 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In spite of intensive therapy, an otherwise fit 34-year-old man died following the hyperpyrexial reaction to an interaction between tranylcypromine and clomipramine." | 3.67 | Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction. ( Tackley, RM; Tregaskis, B, 1987) |
| " fluoxetine and chlorimipramine) or the serotonin precursor 5-hydroxytryptophan in combination with the peripheral decarboxylase inhibitor benserazide, greatly reduced the fever induced by intraventricular prostaglandin E1." | 3.66 | Effects of increasing serotonergic receptor activity in brain on prostagladin E1-induced fever in rabbits. ( Chern, SI; Chern, YF; Lin, MT; Pang, IH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lader, M | 1 |
| Sgaragli, G | 1 |
| Carlà, V | 1 |
| Magnani, M | 1 |
| Galli, A | 1 |
| Power, BM | 1 |
| Pinder, M | 1 |
| Hackett, LP | 1 |
| Ilett, KF | 1 |
| Stevens, E | 1 |
| Roman, A | 1 |
| Houa, M | 1 |
| Razavi, D | 1 |
| Jaspar, N | 1 |
| Lin, MT | 1 |
| Pang, IH | 1 |
| Chern, SI | 1 |
| Chern, YF | 1 |
| Tackley, RM | 1 |
| Tregaskis, B | 1 |
1 review available for clomipramine and Pyrexia
| Article | Year |
|---|---|
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder | 1983 |
1 trial available for clomipramine and Pyrexia
| Article | Year |
|---|---|
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder | 1983 |
5 other studies available for clomipramine and Pyrexia
| Article | Year |
|---|---|
Hypothermia induced in rabbits by intracerebroventricular taurine: specificity and relationships with central serotonin (5-HT) systems.
Topics: Animals; Body Temperature Regulation; Brain Chemistry; Clomipramine; Fenclonine; Fever; Fluoxetine; | 1981 |
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
Severe hyperthermia during tetrabenazine therapy for tardive dyskinesia.
Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Antidepressive Agents, Second-Generation; Antidepressiv | 1998 |
Effects of increasing serotonergic receptor activity in brain on prostagladin E1-induced fever in rabbits.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Clomipramine; Fever; Fluoxetine; Injections, Intra | 1979 |
Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction.
Topics: Adult; Clomipramine; Disseminated Intravascular Coagulation; Drug Interactions; Fever; Humans; Male; | 1987 |