clomipramine has been researched along with Psychoses in 11 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report an improvement in delusions and hallucinations after antidepressant treatment (Clomipramine) in a parkinsonian patient with psychosis and comorbid depression." | 3.74 | Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease. ( Bernardi, S; Meco, G, 2007) |
| "Clomipramine treatment was subsequently discontinued in two patients (off-on-off design), whereas it was discontinued and then reinstituted in three patients (off-on-off-on design)." | 1.29 | Clomipramine treatment of obsessive compulsive symptomatology in schizophrenic patients. ( Benjamin, J; Kaplan, Z; Zohar, J, 1993) |
| "When treated with clomipramine 100 mg daily (plasma level 85 ng/mL), obsessive-compulsive symptoms but not the hallucinations improved significantly, and racing thoughts and grandiosity developed later." | 1.29 | Differential response of psychotic and obsessive symptoms to risperidone in an adolescent. ( Dryden-Edwards, RC; Reiss, AL, 1996) |
| "Two cases of agranulocytosis occurring after addition of a butyrophenone to a course of phenothiazine treatment are reported and possible mechanisms for this interaction are discussed." | 1.28 | Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment. ( Kehoe, R; Young, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meco, G | 1 |
| Bernardi, S | 1 |
| Langer, G | 1 |
| Resch, F | 1 |
| Aschauer, H | 1 |
| Keshavan, MS | 1 |
| Koinig, G | 1 |
| Schönbeck, G | 1 |
| Dittrich, R | 1 |
| Wilens, TE | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wozniak, J | 1 |
| Connor, D | 1 |
| Zohar, J | 1 |
| Kaplan, Z | 1 |
| Benjamin, J | 1 |
| Sichel, DA | 1 |
| Cohen, LS | 1 |
| Dimmock, JA | 1 |
| Rosenbaum, JF | 1 |
| Dryden-Edwards, RC | 1 |
| Reiss, AL | 1 |
| Galinowski, A | 1 |
| Castelnau, C | 1 |
| Spreux-Varoquaux, O | 1 |
| Bourdel, MC | 1 |
| Olie, JP | 1 |
| Loo, H | 1 |
| Poirier, MF | 1 |
| Tissot, R | 1 |
| Chiu, S | 1 |
| McFarlane, AH | 1 |
| Dobson, N | 1 |
| Young, A | 1 |
| Kehoe, R | 1 |
| Ostergaard, PK | 1 |
1 review available for clomipramine and Psychoses
| Article | Year |
|---|---|
The common pathophysiology of monaminergic psychoses: a new hypothesis.
Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrie | 1975 |
1 trial available for clomipramine and Psychoses
| Article | Year |
|---|---|
Evolution of plasma homovanillic acid (HVA) levels during treatment in schizo-affective disorder.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Agents; Chlorpr | 2000 |
9 other studies available for clomipramine and Psychoses
| Article | Year |
|---|---|
Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease.
Topics: Affect; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Antipsychotic | 2007 |
TSH-response patterns to TRH stimulation may indicate therapeutic mechanisms of antidepressant and neuroleptic drugs.
Topics: Adult; Clomipramine; Depressive Disorder; Female; Haloperidol; Humans; Prognosis; Psychiatric Status | 1984 |
Combined pharmacotherapy: an emerging trend in pediatric psychopharmacology.
Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Child Psychiatry; | 1995 |
Clomipramine treatment of obsessive compulsive symptomatology in schizophrenic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Clomipramine; Drug Therapy, Combination; Female; Humans; Ma | 1993 |
Postpartum obsessive compulsive disorder: a case series.
Topics: Adult; Clomipramine; Desipramine; Diagnosis, Differential; Female; Fluoxetine; Follow-Up Studies; Hu | 1993 |
Differential response of psychotic and obsessive symptoms to risperidone in an adolescent.
Topics: 1-Naphthylamine; Adolescent; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Hallucinatio | 1996 |
The treatment of monodelusional psychosis associated with depression.
Topics: Clomipramine; Delusions; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combin | 1990 |
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Respo | 1989 |
Capgras syndrome in senile dementia of the Alzheimer type.
Topics: Aged; Alzheimer Disease; Capgras Syndrome; Clomipramine; Female; Haloperidol; Humans; Psychotic Diso | 1985 |