clomipramine has been researched along with Premenstrual Syndrome in 6 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a previous controlled trial we have shown that premenstrual irritability and depressed mood (premenstrual syndrome) can be effectively reduced by low doses of the potent (but nonselective) serotonin reuptake inhibitor clomipramine taken each day of the menstrual cycle." | 9.07 | Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial. ( Eriksson, E; Hedberg, MA; Sundblad, C, 1993) |
| "Clomipramine (25-50 mg) was administered daily for 5 consecutive menstrual cycles to 5 nondepressed women with severe premenstrual irritability and sadness." | 5.28 | Effect of clomipramine on premenstrual syndrome. ( Andersch, B; Andersson, K; Eriksson, E; Lisjö, P; Modigh, K; Sundblad, C, 1990) |
| "In a previous controlled trial we have shown that premenstrual irritability and depressed mood (premenstrual syndrome) can be effectively reduced by low doses of the potent (but nonselective) serotonin reuptake inhibitor clomipramine taken each day of the menstrual cycle." | 5.07 | Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial. ( Eriksson, E; Hedberg, MA; Sundblad, C, 1993) |
| "Clomipramine (25-50 mg) was administered daily for 5 consecutive menstrual cycles to 5 nondepressed women with severe premenstrual irritability and sadness." | 1.28 | Effect of clomipramine on premenstrual syndrome. ( Andersch, B; Andersson, K; Eriksson, E; Lisjö, P; Modigh, K; Sundblad, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vulink, NC | 1 |
| Denys, D | 1 |
| Bus, L | 1 |
| Westenberg, HG | 1 |
| Labad, J | 1 |
| Menchón, JM | 1 |
| Alonso, P | 1 |
| Segalàs, C | 1 |
| Jiménez, S | 1 |
| Vallejo, J | 1 |
| Sundblad, C | 3 |
| Hedberg, MA | 1 |
| Eriksson, E | 3 |
| Yonkers, KA | 1 |
| Modigh, K | 2 |
| Andersch, B | 2 |
| Lisjö, P | 1 |
| Andersson, K | 1 |
1 review available for clomipramine and Premenstrual Syndrome
| Article | Year |
|---|---|
Antidepressants in the treatment of premenstrual dysphoric disorder.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclohexanols; Depressive Diso | 1997 |
2 trials available for clomipramine and Premenstrual Syndrome
| Article | Year |
|---|---|
Clomipramine administered during the luteal phase reduces the symptoms of premenstrual syndrome: a placebo-controlled trial.
Topics: Adult; Affect; Appetite; Clomipramine; Dietary Carbohydrates; Edema; Female; Humans; Luteal Phase; N | 1993 |
Clomipramine effectively reduces premenstrual irritability and dysphoria: a placebo-controlled trial.
Topics: Adult; Brain; Clomipramine; Depression; Double-Blind Method; Female; Humans; Irritable Mood; Persona | 1992 |
3 other studies available for clomipramine and Premenstrual Syndrome
| Article | Year |
|---|---|
Female hormones affect symptom severity in obsessive-compulsive disorder.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Contraceptives, Oral, Hormonal; De | 2006 |
Oral contraceptive pill use and changes in obsessive-compulsive symptoms.
Topics: Adult; Clomipramine; Contraceptives, Oral, Hormonal; Drug Therapy, Combination; Female; Fluoxetine; | 2006 |
Effect of clomipramine on premenstrual syndrome.
Topics: Adult; Clomipramine; Female; Humans; Premenstrual Syndrome | 1990 |