clomipramine has been researched along with Osteogenic Sarcoma in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A subline of the Ridgway osteogenic sarcoma (ROS)--a murine subcutaneously-growing solid tumour--with moderate resistance (1." | 1.28 | Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine. ( Flanigan, P; Freshney, RI; Hamilton, TG; Kaye, SB; Merry, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merry, S | 1 |
| Hamilton, TG | 1 |
| Flanigan, P | 1 |
| Freshney, RI | 1 |
| Kaye, SB | 1 |
1 other study available for clomipramine and Osteogenic Sarcoma
| Article | Year |
|---|---|
Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clomipramine; Dactinomycin; Doxorubicin; Dr | 1991 |