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clomipramine and Obesity

clomipramine has been researched along with Obesity in 5 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" We studied the effect of acute stimulation of the corticotropic axis on plasma leptin, the ob gene product, in 7 women of normal weight and 12 women with obesity."5.08Plasma leptin and acute serotoninergic stimulation of the corticotropic axis in women who are normal weight or obese. ( Basdevant, A; Guy-Grand, B; Laferrère, B; Lahlou, N; Oppert, JM; Roger, M, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maina, G1
Albert, U1
Salvi, V1
Bogetto, F1
Laferrère, B2
Lahlou, N2
Saltiel, H1
Roger, M2
Basdevant, A2
Oppert, JM2
Guy-Grand, B2
Joseph, MG1
Jouanny, AC1
Chomienne, F1
Champion, G1
Giniès, JL1
Limal, JM1
Gurewitz, R1
Blum, I1
Lavie, P1
Pertzelan, A1
Stivel, M1
Weinstein, R1
Galatzer, A1
Laron, Z1

Reviews

1 review available for clomipramine and Obesity

ArticleYear
[Hypothalamic syndromes. Review of clinical and endocrinal semiology].
    Annales de pediatrie, 1993, Volume: 40, Issue:7

    Topics: Child, Preschool; Clomipramine; Disorders of Excessive Somnolence; Female; Follow-Up Studies; Gonado

1993

Trials

3 trials available for clomipramine and Obesity

ArticleYear
Weight gain during long-term treatment of obsessive-compulsive disorder: a prospective comparison between serotonin reuptake inhibitors.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:10

    Topics: Adult; Ambulatory Care; Citalopram; Clomipramine; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies

2004
Hypersensitivity of the corticotropic axis to the serotoninergic agent clomipramine in obese women.
    Obesity research, 1994, Volume: 2, Issue:4

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Area Under Curve; Clomipramine; Diet, Reducing; Doub

1994
Plasma leptin and acute serotoninergic stimulation of the corticotropic axis in women who are normal weight or obese.
    Obesity research, 1997, Volume: 5, Issue:5

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Body Mass Index; Clomipramine; Double-Blind Method;

1997

Other Studies

1 other study available for clomipramine and Obesity

ArticleYear
Recurrent hypothermia, hypersomnolence, central sleep apnea, hypodipsia, hypernatremia, hypothyroidism, hyperprolactinemia and growth hormone deficiency in a boy--treatment with clomipramine.
    Acta endocrinologica. Supplementum, 1986, Volume: 279

    Topics: Child, Preschool; Clomipramine; Disorders of Excessive Somnolence; Drinking; Growth Hormone; Humans;

1986