clomipramine has been researched along with Neuralgia in 13 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tramadol is a synthetic, centrally acting analgesic with both opioid and nonopioid analgesic activity." | 6.68 | [Treatment of post-herpes zoster pain with tramadol. Results of an open pilot study versus clomipramine with or without levomepromazine]. ( Göbel, H; Stadler, T, 1997) |
| "Tramadol is a synthetic, centrally acting analgesic with both opioid and nonopioid analgesic activity." | 2.68 | [Treatment of post-herpes zoster pain with tramadol. Results of an open pilot study versus clomipramine with or without levomepromazine]. ( Göbel, H; Stadler, T, 1997) |
| "Clomipramine was better tolerated." | 2.65 | Clomipramine and amitriptyline in the treatment of severe pain. ( Carasso, RL; Streifler, M; Yehuda, S, 1979) |
| "Abolition of mechanical hyperalgesia was observed in mononeuropathic rats after five injections of clomipramine (5 mg·kg(-1) , s." | 1.37 | Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain? ( Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS, 2011) |
| "The basis of the treatment of painful diabetic neuropathy is the use of drugs that block the transmission of pain (antineuritics) and a good metabolic control of underlying disease." | 1.33 | [Intensified insulin therapy plus antineuritic medication is more effective than antineuritics alone in painful diabetic neuropathy]. ( Bastías A, MJ; Olmos C, P; Toro C, L, 2006) |
| "20 patients with neuropathic pain syndromes due to tumor-infiltration, who had not responded to conventional analgesics including strong opioids, received additional combination anti-convulsant and anti-depressant treatment." | 1.28 | Anti-depressants and anti-convulsants for the treatment of neuropathic pain syndromes in cancer patients. ( Höffken, K; Kloke, M; Olbrich, H; Schmidt, CG, 1991) |
| " A dosing strategy for the combbination of clomipramine and haloperidol is described." | 1.26 | [The treatment of chronic pain symptoms with psychotropic drugs (author's transl)]. ( Kocher, R, 1976) |
| "Clomipramine used alone is an affective analgesic against organic pain due to a lesion of the peripheral nervous system, in particular post-herpetic pain." | 1.26 | [The treatment of organic pain of the peripheral nervous system using clomipramine. 30 cases (author's transl)]. ( Castaigne, P; Laplane, D; Morales, R, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Derry, S | 1 |
| Wiffen, PJ | 1 |
| Aldington, D | 1 |
| Moore, RA | 1 |
| Wattiez, AS | 1 |
| Libert, F | 1 |
| Privat, AM | 1 |
| Loiodice, S | 1 |
| Fialip, J | 1 |
| Eschalier, A | 1 |
| Courteix, C | 1 |
| Farghaly, HS | 1 |
| Abdel-Zaher, AO | 1 |
| Mostafa, MG | 1 |
| Kotb, HI | 1 |
| Bastías A, MJ | 1 |
| Toro C, L | 1 |
| Olmos C, P | 1 |
| von Albert, HH | 1 |
| Langohr, HD | 1 |
| Stöhr, M | 1 |
| Petruch, F | 1 |
| Haberfellner, EM | 1 |
| Göbel, H | 1 |
| Stadler, T | 1 |
| Kocher, R | 1 |
| Castaigne, P | 1 |
| Laplane, D | 1 |
| Morales, R | 1 |
| Gerson, GR | 1 |
| Jones, RB | 1 |
| Luscombe, DK | 1 |
| Carasso, RL | 1 |
| Yehuda, S | 1 |
| Streifler, M | 1 |
| Kloke, M | 1 |
| Höffken, K | 1 |
| Olbrich, H | 1 |
| Schmidt, CG | 1 |
1 review available for clomipramine and Neuralgia
| Article | Year |
|---|---|
Nortriptyline for neuropathic pain in adults.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanecarbox | 2015 |
4 trials available for clomipramine and Neuralgia
| Article | Year |
|---|---|
An open and double-blind cross-over study on the efficacy of clomipramine (Anafranil) in patients with painful mono- and polyneuropathies.
Topics: Antipsychotic Agents; Aspirin; Causalgia; Clinical Trials as Topic; Clomipramine; Double-Blind Metho | 1982 |
[Treatment of post-herpes zoster pain with tramadol. Results of an open pilot study versus clomipramine with or without levomepromazine].
Topics: Aged; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Drug | 1997 |
Studies on the concomitant use of carbamazepine and clomipramine for the relief of post-herpetic neuralgia.
Topics: Age Factors; Aged; Carbamazepine; Clomipramine; Dibenzazepines; Drug Combinations; Electric Stimulat | 1977 |
Clomipramine and amitriptyline in the treatment of severe pain.
Topics: Adult; Aged; Amitriptyline; Clomipramine; Female; Headache; Humans; Male; Middle Aged; Neuralgia; Pa | 1979 |
8 other studies available for clomipramine and Neuralgia
| Article | Year |
|---|---|
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experime | 2011 |
Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model.
Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior | 2012 |
[Intensified insulin therapy plus antineuritic medication is more effective than antineuritics alone in painful diabetic neuropathy].
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Analgesics; Clomipramine; Cyclohexanecarboxylic A | 2006 |
[Therapy in neurology. Part 9: Therapy of causally untreatable pain conditions].
Topics: Antipsychotic Agents; Clomipramine; Dose-Response Relationship, Drug; Electric Stimulation; Humans; | 1981 |
[Sexual side-effects of clomipramine--a psychopharmacologic personal experience].
Topics: Clomipramine; Ejaculation; Herpes Zoster; Humans; Male; Neuralgia; Selective Serotonin Reuptake Inhi | 1996 |
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, C | 1976 |
[The treatment of organic pain of the peripheral nervous system using clomipramine. 30 cases (author's transl)].
Topics: Adult; Aged; Clomipramine; Diazepam; Dibenzazepines; Drug Evaluation; Female; Fludrocortisone; Herpe | 1979 |
Anti-depressants and anti-convulsants for the treatment of neuropathic pain syndromes in cancer patients.
Topics: Analgesics; Anticonvulsants; Antidepressive Agents; Clomipramine; Drug Therapy, Combination; Haloper | 1991 |