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clomipramine and Myoclonic Jerk

clomipramine has been researched along with Myoclonic Jerk in 16 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Research Excerpts

ExcerptRelevanceReference
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."6.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."2.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
"This treatment produced also myoclonus and increased the time spent resting during trials."1.27Effects of the chronic ingestion of therapeutic doses of chlorimipramine on the behavioral action of agonists and antagonists of serotonin in male rats. ( Broitman, ST; Fóscolo, MR; Rodríguez Echandía, EL, 1983)
"PGE2 reduced DDT-induced myoclonus; this effect was blocked by PPP."1.26Role of prostaglandins in the antimyoclonic action of clonazepam. ( Hwang, EC; Van Woert, MH, 1981)
"p,p'-DDT-treated rats had increased concentrations of 5-hydroxyindoleacetic acid (5-HIAA) in seven regional areas, but serotonin was increased only in the midbrain and cerebellum."1.26p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. ( Hwang, EC; Van Woert, MH, 1978)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's4 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horga, G1
Horga, A1
Baeza, I1
Castro-Fornieles, J1
Lázaro, L1
Pons, A1
Rodríguez Echandía, EL1
Broitman, ST1
Fóscolo, MR1
Insel, TR1
Roy, BF1
Cohen, RM1
Murphy, DL1
Hwang, EC2
Van Woert, MH3
Lejoyeux, M2
Rouillon, F1
Adès, J2
Nijhawan, PK1
Katz, G1
Winter, S1
Bloem, BR1
Lammers, GJ1
Roofthooft, DW1
De Beaufort, AJ1
Brouwer, OF1
Rosenbaum, D1
Tseng, LF1
Harris, RA1
Loh, NH1
Fineyre, F1
Fukuzako, H1
Hokazono, Y1
Tominaga, H1
Hirakawa, K1
Matsumoto, K1
Lieberman, JA1
Kane, JM1
Reife, R1
Casas, M1
Garcia-Ribera, C1
Alvarez, E1
Udina, C1
Queralto, JM1
Grau, JM1
Myers, BA1
Klerman, GL1
Hartmann, E1
Marley, E1
Wozniak, KM1

Reviews

1 review available for clomipramine and Myoclonic Jerk

ArticleYear
Neuromuscular effects of monoamine oxidase inhibitors.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adult; Animals; Clomipramine; Clorgyline; Depressive Disorder; Female; Humans;

1986

Trials

1 trial available for clomipramine and Myoclonic Jerk

ArticleYear
Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arousal; Brain; Clomipramine; Depressive Disorder; Female; Humans; M

1993

Other Studies

14 other studies available for clomipramine and Myoclonic Jerk

ArticleYear
Drug-induced speech dysfluency and myoclonus preceding generalized tonic-clonic seizures in an adolescent male with schizophrenia.
    Journal of child and adolescent psychopharmacology, 2010, Volume: 20, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Clomipramine; Clozapine; Epilepsy, Tonic-Clonic; Humans; Male; Myo

2010
Effects of the chronic ingestion of therapeutic doses of chlorimipramine on the behavioral action of agonists and antagonists of serotonin in male rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Clomipramine; Exploratory Behavior; Fluoxetine; Male; Methysergide; Mo

1983
Possible development of the serotonin syndrome in man.
    The American journal of psychiatry, 1982, Volume: 139, Issue:7

    Topics: Adult; Clomipramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; My

1982
Role of prostaglandins in the antimyoclonic action of clonazepam.
    European journal of pharmacology, 1981, Apr-24, Volume: 71, Issue:1

    Topics: Animals; Benzodiazepinones; Clomipramine; Clonazepam; Indomethacin; Male; Mice; Myoclonus; Polyphlor

1981
Psychiatric illness and the serotonin syndrome: an emerging adverse drug effect leading to intensive care unit admission.
    Critical care medicine, 1996, Volume: 24, Issue:6

    Topics: Alcohol Withdrawal Delirium; Buspirone; Clomipramine; Diagnosis, Differential; Drug Therapy, Combina

1996
Clomipramine withdrawal in newborns.
    Archives of disease in childhood. Fetal and neonatal edition, 1999, Volume: 81, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Female; Humans; Infant, Newborn; Myoclonus; P

1999
p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus.
    Neurology, 1978, Volume: 28, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Clomipramine; DDT; Hydroxyindoleacetic Acid; Isomeris

1978
L-5-hydroxytryptophan therapy in myoclonus.
    Advances in neurology, 1979, Volume: 26

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clomipramine; Double-Blind Method; Drug Eva

1979
Blockade of para-methoxyamphetamine- induced serotonergic effects by chlorimipramine.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:1

    Topics: Amphetamines; Animals; Cerebral Cortex; Chromatography, Thin Layer; Clomipramine; Conditioning, Oper

1978
The serotonin syndrome.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Adult; Clomipramine; Depressive Disorder; Humans; Male; Myoclonus; Serotonin; Syndrome

1992
Jerk-locked averaging and somatosensory evoked potential in tricyclic-induced myoclonus: a case report.
    The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:4

    Topics: Adult; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalography;

1989
Myoclonic movements as a side-effect of treatment with therapeutic doses of clomipramine.
    International clinical psychopharmacology, 1987, Volume: 2, Issue:4

    Topics: Adult; Aged; Clomipramine; Depression; Female; Humans; Male; Middle Aged; Myoclonus

1987
Nocturnal cataclysms with myoclonus: a new side effect of clomipramine.
    The American journal of psychiatry, 1986, Volume: 143, Issue:11

    Topics: Clomipramine; Depressive Disorder; Female; Humans; Middle Aged; Myoclonus; Sleep Wake Disorders

1986
Interactions between relatively selective monoamine oxidase inhibitors and an inhibitor of 5-hydroxytryptamine re-uptake, clomipramine.
    Journal of psychiatric research, 1985, Volume: 19, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Body Temperature; Cerebral Cortex; Clomipramine; Clorgyline; Drug Int

1985