clomipramine has been researched along with Metastase in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "20 patients with neuropathic pain syndromes due to tumor-infiltration, who had not responded to conventional analgesics including strong opioids, received additional combination anti-convulsant and anti-depressant treatment." | 1.28 | Anti-depressants and anti-convulsants for the treatment of neuropathic pain syndromes in cancer patients. ( Höffken, K; Kloke, M; Olbrich, H; Schmidt, CG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kloke, M | 1 |
| Höffken, K | 1 |
| Olbrich, H | 1 |
| Schmidt, CG | 1 |
1 other study available for clomipramine and Metastase
| Article | Year |
|---|---|
Anti-depressants and anti-convulsants for the treatment of neuropathic pain syndromes in cancer patients.
Topics: Analgesics; Anticonvulsants; Antidepressive Agents; Clomipramine; Drug Therapy, Combination; Haloper | 1991 |