clomipramine has been researched along with MS (Multiple Sclerosis) in 2 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In mice with experimental autoimmune encephalomyelitis, a model of MS, clomipramine ameliorates clinical signs of acute and chronic phases." | 5.46 | Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic. ( Faissner, S; Fan, Y; Kaushik, DK; Koch, M; Metz, L; Mishra, M; Rauw, G; Silva, C; Wang, J; Yong, VW, 2017) |
| "A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a." | 5.31 | Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. ( Dubisar, BM; Farrar, CD; Khan, R; Stoner, SC, 2002) |
| "In mice with experimental autoimmune encephalomyelitis, a model of MS, clomipramine ameliorates clinical signs of acute and chronic phases." | 1.46 | Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic. ( Faissner, S; Fan, Y; Kaushik, DK; Koch, M; Metz, L; Mishra, M; Rauw, G; Silva, C; Wang, J; Yong, VW, 2017) |
| "A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a." | 1.31 | Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. ( Dubisar, BM; Farrar, CD; Khan, R; Stoner, SC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faissner, S | 1 |
| Mishra, M | 1 |
| Kaushik, DK | 1 |
| Wang, J | 1 |
| Fan, Y | 1 |
| Silva, C | 1 |
| Rauw, G | 1 |
| Metz, L | 1 |
| Koch, M | 1 |
| Yong, VW | 1 |
| Dubisar, BM | 1 |
| Stoner, SC | 1 |
| Khan, R | 1 |
| Farrar, CD | 1 |
2 other studies available for clomipramine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic.
Topics: Animals; Axons; B-Lymphocytes; Blood-Brain Barrier; Cell Proliferation; Cells, Cultured; Clomipramin | 2017 |
Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.
Topics: Adult; Asperger Syndrome; Basal Ganglia Diseases; Clomipramine; Humans; Interferon beta-1a; Interfer | 2002 |