clomipramine has been researched along with Hypothermia, Accidental in 10 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Depressing functional serotonin or depleting serotonin levels in rat brains with either p-chlorophenylalanine, 5,6-dihydroxytryptamine or raphe lesions greatly enhanced hypothermia induced by chloropromazine (CPZ)." | 7.66 | Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats. ( Chern, YF; Chow, CF; Li, YP; Lin, MT, 1979) |
| " Desmethylclomipramine was shown to be present in plasma in higher concentrations than the parent compound, to be strongly active in reversing or suppressing reserpine-induced hypothermia, to possess anticholinergic activity on gastrointestinal smooth muscle, inhibiting motility and antagonizing muscarinic receptors, though to a lesser extent than clomipramine." | 3.66 | Some pharmacological aspects of desmethylclomipramine. ( Benfield, DP; Harries, CM; Luscombe, DK, 1980) |
| "Depressing functional serotonin or depleting serotonin levels in rat brains with either p-chlorophenylalanine, 5,6-dihydroxytryptamine or raphe lesions greatly enhanced hypothermia induced by chloropromazine (CPZ)." | 3.66 | Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats. ( Chern, YF; Chow, CF; Li, YP; Lin, MT, 1979) |
| "Clomipramine treatment was beneficial." | 1.34 | Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome. ( De Bleecker, JL; Hemelsoet, DM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, Q | 1 |
| Huang, Z | 1 |
| Ip, S | 1 |
| Che, C | 1 |
| Kudoh, A | 1 |
| Takase, H | 1 |
| Takazawa, T | 1 |
| Hemelsoet, DM | 1 |
| De Bleecker, JL | 1 |
| Benfield, DP | 1 |
| Harries, CM | 1 |
| Luscombe, DK | 1 |
| Soliman, KF | 1 |
| Gabriel, NN | 1 |
| Rubat, C | 1 |
| Coudert, P | 1 |
| Bastide, P | 1 |
| Tronche, P | 1 |
| Joseph, MG | 1 |
| Jouanny, AC | 1 |
| Chomienne, F | 1 |
| Champion, G | 1 |
| Giniès, JL | 1 |
| Limal, JM | 1 |
| Lin, MT | 1 |
| Chern, YF | 1 |
| Chow, CF | 1 |
| Li, YP | 1 |
| Musa, AB | 1 |
| Smith, CS | 1 |
| Gurewitz, R | 1 |
| Blum, I | 1 |
| Lavie, P | 1 |
| Pertzelan, A | 1 |
| Stivel, M | 1 |
| Weinstein, R | 1 |
| Galatzer, A | 1 |
| Laron, Z | 1 |
1 review available for clomipramine and Hypothermia, Accidental
| Article | Year |
|---|---|
[Hypothalamic syndromes. Review of clinical and endocrinal semiology].
Topics: Child, Preschool; Clomipramine; Disorders of Excessive Somnolence; Female; Follow-Up Studies; Gonado | 1993 |
1 trial available for clomipramine and Hypothermia, Accidental
| Article | Year |
|---|---|
Chronic treatment with antidepressants decreases intraoperative core hypothermia.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 2003 |
8 other studies available for clomipramine and Hypothermia, Accidental
| Article | Year |
|---|---|
Antidepressant-like effect of ethanol extract from Paeonia lactiflora in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Blepharoptosis; Clomipramine; Depression; Dise | 2008 |
Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome.
Topics: Body Temperature; Brain Injuries; Clomipramine; Corpus Callosum; Humans; Hypothermia; Magnetic Reson | 2007 |
Some pharmacological aspects of desmethylclomipramine.
Topics: Clomipramine; Depression, Chemical; Gastrointestinal Motility; Hypothermia; Ileum; Neurotransmitter | 1980 |
Effect of biogenic amines reuptake inhibition on ethanol induced hypothermia.
Topics: Animals; Biogenic Amines; Clomipramine; Desipramine; Ethanol; Hypothermia; Male; Mice; Mice, Inbred | 1983 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Bleph | 1995 |
Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats.
Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Body Temperature Regulation; Brain; Chlorprom | 1979 |
Neonatal effects of maternal clomipramine therapy.
Topics: Clomipramine; Dibenzazepines; Female; Humans; Hypothermia; Infant, Newborn; Infant, Newborn, Disease | 1979 |
Recurrent hypothermia, hypersomnolence, central sleep apnea, hypodipsia, hypernatremia, hypothyroidism, hyperprolactinemia and growth hormone deficiency in a boy--treatment with clomipramine.
Topics: Child, Preschool; Clomipramine; Disorders of Excessive Somnolence; Drinking; Growth Hormone; Humans; | 1986 |