clomipramine has been researched along with Hypomania in 2 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High doses of antidepressants, particularly clomipramine and selective serotonin reuptake inhibitors (SSRIs), are the well-established treatment for obsessive-compulsive disorder (OCD), but manic/hypomanic episodes are potential adverse events associated with this treatment." | 5.12 | First manic/hypomanic episode in obsessive-compulsive disorder patients treated with antidepressants: A systematic review. ( Alemany-Navarro, M; Alonso, P; Bertolín, S; Crespo, JM; Jiménez-Murcia, S; Menchón, JM; Real, E; Segalàs, C; Soria, V, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joas, E | 1 |
| Jonsson, L | 1 |
| Viktorin, A | 1 |
| Smedler, E | 1 |
| Pålsson, E | 1 |
| Goodwin, GM | 1 |
| Landén, M | 1 |
| Bertolín, S | 1 |
| Alonso, P | 1 |
| Segalàs, C | 1 |
| Real, E | 1 |
| Alemany-Navarro, M | 1 |
| Soria, V | 1 |
| Jiménez-Murcia, S | 1 |
| Crespo, JM | 1 |
| Menchón, JM | 1 |
1 review available for clomipramine and Hypomania
| Article | Year |
|---|---|
First manic/hypomanic episode in obsessive-compulsive disorder patients treated with antidepressants: A systematic review.
Topics: Antidepressive Agents; Clomipramine; Humans; Mania; Obsessive-Compulsive Disorder; Selective Seroton | 2021 |
1 other study available for clomipramine and Hypomania
| Article | Year |
|---|---|
Effect of CYP2C19 polymorphisms on antidepressant prescription patterns and treatment emergent mania in bipolar disorder.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Cytochrome P-450 CYP2C19; Cyto | 2023 |