clomipramine has been researched along with Heart Diseases in 4 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clomipramine appeared much more effective and better tolerated than fluoxetine in this very old patient despite its potential anticholinergic effect and the coexistence of Alzheimer disease." | 7.70 | Treatment of obsessive-compulsive disorder using clomipramine in a very old patient. ( Trappler, B, 1999) |
| " In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis." | 3.80 | Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014) |
| "Clomipramine appeared much more effective and better tolerated than fluoxetine in this very old patient despite its potential anticholinergic effect and the coexistence of Alzheimer disease." | 3.70 | Treatment of obsessive-compulsive disorder using clomipramine in a very old patient. ( Trappler, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, JJ | 1 |
| Xu, YQ | 1 |
| He, JH | 1 |
| Yu, HP | 1 |
| Huang, CJ | 1 |
| Gao, JM | 1 |
| Dong, QX | 1 |
| Xuan, YX | 1 |
| Li, CQ | 1 |
| Agnoli, A | 1 |
| Martucci, N | 1 |
| Ciabatti, P | 1 |
| Caratozzolo, P | 1 |
| Rulli, V | 1 |
| Sollecito, A | 1 |
| Trappler, B | 1 |
| Kielholz, VP | 1 |
4 other studies available for clomipramine and Heart Diseases
| Article | Year |
|---|---|
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease | 2014 |
[The problem of side-effects: cardiotoxicity (author's transl)].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dibenzocyclohept | 1981 |
Treatment of obsessive-compulsive disorder using clomipramine in a very old patient.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; B | 1999 |
[The pharmacotherapy of masked depression].
Topics: Adrenergic beta-Agonists; Anthracenes; Clomipramine; Depression; Dibenzazepines; Drug Therapy, Combi | 1975 |