clomipramine has been researched along with Genetic Predisposition in 5 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Narcolepsy is an emblematic, unique disease within sleep disorders that is characterised by excessive daytime sleepiness, cataplexy and other abnormal manifestations of REM sleep." | 2.48 | [Diagnostic and therapeutic update in narcolepsy]. ( Santamaria-Cano, J, 2012) |
| "Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness and cataplexy." | 2.43 | Molecular genetics and treatment of narcolepsy. ( Dauvilliers, Y; Tafti, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cordes, J | 1 |
| Larisch, R | 1 |
| Henning, U | 1 |
| Thünker, J | 1 |
| Werner, C | 1 |
| Orozco, G | 1 |
| Mayoral, F | 1 |
| Rivas, F | 1 |
| Auburger, G | 1 |
| Tosch, M | 1 |
| Rietschel, M | 1 |
| Gaebel, W | 1 |
| Müller, HW | 1 |
| Klimke, A | 1 |
| Santamaria-Cano, J | 1 |
| Ventura, R | 1 |
| Cabib, S | 1 |
| Puglisi-Allegra, S | 1 |
| Dauvilliers, Y | 1 |
| Tafti, M | 1 |
| Marchesi, C | 1 |
| Tonna, M | 1 |
| Maggini, C | 1 |
2 reviews available for clomipramine and Genetic Predisposition
| Article | Year |
|---|---|
[Diagnostic and therapeutic update in narcolepsy].
Topics: Adolescent; Adult; Age of Onset; Animals; Autoimmune Diseases; Benzhydryl Compounds; Cataplexy; Chil | 2012 |
Molecular genetics and treatment of narcolepsy.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Catechol O-Methyltransferase; Centr | 2006 |
3 other studies available for clomipramine and Genetic Predisposition
| Article | Year |
|---|---|
Abnormal neuroendocrine response to clomipramine in hereditary affective psychosis.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipramine; Depressive Disorder, | 2009 |
Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral 'despair' in a mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Dise | 2002 |
Obsessive-compulsive disorder followed by psychotic episode in long-term ecstasy misuse.
Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Antipsychotic Agents; B | 2009 |