Page last updated: 2024-10-25

clomipramine and Esophageal Spasm

clomipramine has been researched along with Esophageal Spasm in 1 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Research Excerpts

ExcerptRelevanceReference
"The cause of diffuse esophageal spasm (DES) has not been clearly established, and effective treatment is lacking."1.30Antidepressant treatment of patients with diffuse esophageal spasm: a psychosomatic approach. ( Handa, M; Hayashi, H; Kanazawa, F; Kubo, C; Mine, K; Tsuchida, O; Yamamoto, H, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handa, M1
Mine, K1
Yamamoto, H1
Hayashi, H1
Tsuchida, O1
Kanazawa, F1
Kubo, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial[NCT01269788]Phase 2/Phase 3144 participants (Actual)Interventional2010-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for clomipramine and Esophageal Spasm

ArticleYear
Antidepressant treatment of patients with diffuse esophageal spasm: a psychosomatic approach.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri

1999