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clomipramine and Epileptiform Neuralgia

clomipramine has been researched along with Epileptiform Neuralgia in 5 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Research Excerpts

ExcerptRelevanceReference
"There is low-quality evidence that the effect of tizanidine is not significantly different than that of carbamazepine in treating trigeminal neuralgia."4.89Non-antiepileptic drugs for trigeminal neuralgia. ( Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M, 2013)
"To develop a behavioral model in mice that is capable of mimicking some distinctive symptoms of human posttraumatic trigeminal neuropathic pain such as spontaneous pain, cold allodynia, and chemical÷inflammatory hyperalgesia, and to use this model to investigate the antinociceptive effects of clomipramine and tramadol, two drugs used for the treatment of neuropathic pain."3.77Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice. ( Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T, 2011)
"Clomipramine was better tolerated."2.65Clomipramine and amitriptyline in the treatment of severe pain. ( Carasso, RL; Streifler, M; Yehuda, S, 1979)
"Tizanidine was investigated in two trials."2.43Non-antiepileptic drugs for trigeminal neuralgia. ( He, L; Wu, B; Zhou, M, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, J1
Yang, M2
Zhou, M3
He, L3
Chen, N2
Zakrzewska, JM2
Alvarez, P1
Brun, A1
Labertrandie, A1
Lopez, J1
Correa, A1
Constandil, L1
Hernández, A1
Pelissier, T1
Wu, B1
Carasso, RL1
Yehuda, S1
Streifler, M1

Reviews

3 reviews available for clomipramine and Epileptiform Neuralgia

ArticleYear
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2013, Dec-03, Issue:12

    Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans

2013
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propo

2011
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Ran

2006

Trials

1 trial available for clomipramine and Epileptiform Neuralgia

ArticleYear
Clomipramine and amitriptyline in the treatment of severe pain.
    The International journal of neuroscience, 1979, Volume: 9, Issue:3

    Topics: Adult; Aged; Amitriptyline; Clomipramine; Female; Headache; Humans; Male; Middle Aged; Neuralgia; Pa

1979

Other Studies

1 other study available for clomipramine and Epileptiform Neuralgia

ArticleYear
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
    Journal of orofacial pain, 2011,Fall, Volume: 25, Issue:4

    Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde;

2011