clomipramine has been researched along with Drug Overdose in 17 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of acute chemical pancreatitis and associated prolonged ileus following an acute overdose of the tricyclic antidepressant clomipramine by an adult is reported." | 7.69 | Acute chemical pancreatitis associated with a tricyclic antidepressant (clomipramine) overdose. ( Benitez, JG; Hodgman, M; Martin, TG; Roberge, RJ, 1994) |
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 5.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| "A fatal case of drowning under the influence of multiple psychotropic drugs, such as quetiapine, escitalopram, aripiprazole and flunitrazepam, is presented." | 3.91 | An autopsy case of drowning under the influence of multiple psychotropic drugs. ( , 2019) |
| "A case of acute chemical pancreatitis and associated prolonged ileus following an acute overdose of the tricyclic antidepressant clomipramine by an adult is reported." | 3.69 | Acute chemical pancreatitis associated with a tricyclic antidepressant (clomipramine) overdose. ( Benitez, JG; Hodgman, M; Martin, TG; Roberge, RJ, 1994) |
| "Gastric pharmacobezoars are a rare entity that can induce mechanical gastric outlet obstructions and sometimes prolong toxic pharmacological effects." | 1.51 | Endoscopic removal of a gastric pharmacobezoar induced by clomipramine, lorazepam, and domperidone overdose: a case report. ( Challet, C; Christin, L; von Düring, S, 2019) |
| "We concluded that he had died of pulmonary edema due to combined drug intoxication including proprietary antitussives and cold remedies." | 1.36 | A fatal case of potential chronic overdoses of prescribed and proprietary remedies. ( Nakagawa, T; Nishi, K; Takase, I; Yamamoto, Y, 2010) |
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 1.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Sandhu, AK | 1 |
| van Schip, AM | 1 |
| Driessen, L | 1 |
| van Dorp, W | 1 |
| von Düring, S | 1 |
| Challet, C | 1 |
| Christin, L | 1 |
| Magdalan, J | 1 |
| Zawadzki, M | 1 |
| Słoka, T | 1 |
| Sozański, T | 1 |
| Takase, I | 1 |
| Yamamoto, Y | 1 |
| Nakagawa, T | 1 |
| Nishi, K | 1 |
| Power, BM | 1 |
| Pinder, M | 1 |
| Hackett, LP | 1 |
| Ilett, KF | 1 |
| Hernandez, AF | 1 |
| Montero, MN | 1 |
| Pla, A | 1 |
| Villanueva, E | 1 |
| Neuvonen, PJ | 1 |
| Pohjola-Sintonen, S | 1 |
| Tacke, U | 1 |
| Vuori, E | 1 |
| Romano, G | 1 |
| Di Bono, G | 1 |
| Dale, O | 1 |
| Hole, A | 1 |
| Roberge, RJ | 1 |
| Martin, TG | 1 |
| Hodgman, M | 1 |
| Benitez, JG | 1 |
| Nierenberg, DW | 1 |
| Semprebon, M | 1 |
| Iwersen, S | 1 |
| Schmoldt, A | 1 |
| François, B | 1 |
| Marquet, P | 1 |
| Desachy, A | 1 |
| Roustan, J | 1 |
| Lachatre, G | 1 |
| Gastinne, H | 1 |
| Ferrer-Dufol, A | 1 |
| Perez-Aradros, C | 1 |
| Murillo, EC | 1 |
| Marques-Alamo, JM | 1 |
| Yoav, G | 1 |
| Odelia, G | 1 |
| Shaltiel, C | 1 |
| Goor, Y | 1 |
| Goor, O | 1 |
| Cabili, S | 1 |
| Lheureux, P | 1 |
| Vranckx, M | 1 |
| Leduc, D | 1 |
| Askenasi, R | 1 |
17 other studies available for clomipramine and Drug Overdose
| Article | Year |
|---|---|
An autopsy case of drowning under the influence of multiple psychotropic drugs.
Topics: Adult; Autopsy; Chlorpromazine; Clomipramine; Drowning; Drug Overdose; Female; Flunitrazepam; Forens | 2019 |
[Pharmacobezoar in a woman with a clomipramine intoxication].
Topics: Bezoars; Clomipramine; Delayed-Action Preparations; Drug Overdose; Female; Humans; Middle Aged; Stom | 2021 |
Endoscopic removal of a gastric pharmacobezoar induced by clomipramine, lorazepam, and domperidone overdose: a case report.
Topics: Adult; Antidepressive Agents, Tricyclic; Bezoars; Charcoal; Clomipramine; Delayed-Action Preparation | 2019 |
Suicidal overdose with relapsing clomipramine concentrations due to a large gastric pharmacobezoar.
Topics: Adult; Antidepressive Agents, Tricyclic; Bezoars; Clomipramine; Delayed-Action Preparations; Doxepin | 2013 |
A fatal case of potential chronic overdoses of prescribed and proprietary remedies.
Topics: Adult; Analgesics; Caffeine; Chlorpromazine; Clomipramine; Drug Overdose; Fatal Outcome; Heart Arres | 2010 |
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
Fatal moclobemide overdose or death caused by serotonin syndrome?
Topics: Adult; Antidepressive Agents; Benzamides; Cause of Death; Clomipramine; Drug Interactions; Drug Over | 1995 |
Five fatal cases of serotonin syndrome after moclobemide-citalopram or moclobemide-clomipramine overdoses.
Topics: Adult; Benzamides; Citalopram; Clomipramine; Drug Interactions; Drug Overdose; Fatal Outcome; Female | 1993 |
A fatality involving clothiapine and clomipramine.
Topics: Adult; Clomipramine; Dibenzothiazepines; Drug Overdose; Fatal Outcome; Humans; Male; Suicide | 1994 |
Biphasic time-course of serum concentrations of clomipramine and desmethylclomipramine after a near-fatal overdose.
Topics: Adult; Chromatography, High Pressure Liquid; Clomipramine; Drug Overdose; Half-Life; Humans; Male | 1994 |
Acute chemical pancreatitis associated with a tricyclic antidepressant (clomipramine) overdose.
Topics: Acute Disease; Clomipramine; Drug Overdose; Female; Humans; Intestinal Obstruction; Middle Aged; Pan | 1994 |
The central nervous system serotonin syndrome.
Topics: Adult; Central Nervous System; Clomipramine; Depressive Disorder; Dextromethorphan; Drug Interaction | 1993 |
Three suicide attempts with moclobemide.
Topics: Antidepressive Agents, Tricyclic; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female | 1996 |
Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association.
Topics: Antidepressive Agents; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female; Humans; M | 1997 |
Fatal serotonin syndrome caused by moclobemide-clomipramine overdose.
Topics: Adult; Benzamides; Clomipramine; Clorazepate Dipotassium; Drug Interactions; Drug Overdose; Fatal Ou | 1998 |
A lipid emulsion reduces mortality from clomipramine overdose in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Drug Overdose; Fat Emulsions, Intravenous; | 2002 |
Risks of flumazenil in mixed benzodiazepine-tricyclic antidepressant overdose: report of a preliminary study in the dog.
Topics: Amitriptyline; Animals; Clomipramine; Dogs; Drug Overdose; Female; Flumazenil; Male; Risk Factors | 1992 |