clomipramine has been researched along with Disease Models, Animal in 96 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.08) | 18.7374 |
| 1990's | 19 (19.79) | 18.2507 |
| 2000's | 32 (33.33) | 29.6817 |
| 2010's | 37 (38.54) | 24.3611 |
| 2020's | 6 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Hu, J; Li, M; Li, W; Liu, G; Liu, Q; Shi, C; Wu, H; Zhang, S | 1 |
| Beracochea, D; Dore, J; Dries, A; Faucher, P; Leboyer, M; Mousset, PY | 1 |
| Abdel-Moneim, AM; Abdelmeguid, NE; Hammad, TM; Salam, SA | 1 |
| Arteaga-Silva, M; Bonilla-Jaime, H; Cerbón, M; Limón-Morales, O; Molina-Jiménez, T; Morales-Quintero, K | 1 |
| Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Tripathi, SJ | 1 |
| Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N | 1 |
| Adornetto, A; Bagetta, G; Bano, D; Bertan, F; Cavaliere, F; Corasaniti, MT; Fornarelli, A; Marsal-Cots, A; Morrone, LA; Nicotera, P; Russo, R | 1 |
| Abdelmelek, H; Ammari, M; Lassoued, A; Othman, H; Sakly, M | 1 |
| Feng, P; Huang, C | 1 |
| Baez, A; Bazán, PC; Cremonezzi, D; Esteves, B; Fauro, R; Lo Presti, MS; Paglini-Oliva, PA; Rivarola, HW; Sanchez Negrete, O; Strauss, M | 1 |
| Ishikawa, M; Maekawa, K; Murayama, M; Nakatsu, N; Saito, K; Saito, Y; Senoo, Y; Urata, M; Yamada, H | 1 |
| Chen, L; Chu, X; Feng, X; Hu, X; Li, J; Li, Z; Lü, L; Pan, L; Qin, D; Xu, L; Yang, Q; Yang, S; Yin, Y | 1 |
| Aoki, MP; García, MC; Jimenez-Kairuz, AF; Manzo, RH; Ponce, NE; Sanmarco, LM | 1 |
| Hatalova, H; Pistikova, A; Radostova, D; Stuchlik, A; Vales, K | 1 |
| Duque, A; Monleón, S; Vinader-Caerols, C | 1 |
| Che, C; Huang, Z; Ip, S; Mao, Q | 1 |
| Battaglia, G; Bruno, V; Caruso, A; Girardi, P; Gruber, SH; Marchiafava, M; Mathè, AA; Matrisciano, F; Melchiorri, D; Nicoletti, F; Orlando, R; Tatarelli, R | 1 |
| Amato, D; Borsini, F; Nencini, P; Stasi, MA | 1 |
| Antoniou, K; Bekris, S; Dalla, C; Kokras, N; Ovestreet, DH; Papadopoulou-Daifoti, Z; Xagoraris, M | 1 |
| Cave, G; Harvey, M; Hoggett, K | 1 |
| Gaio, EJ; Rosing, CK; Soletti, AC | 1 |
| Li, B; Liu, Q; Wang, YQ; Wu, GC; Yu, J; Zhu, HY | 1 |
| Griva, E; Ioannou, K; Papadopoulou-Daifoti, Z; Pitychoutis, PM; Tsitsilonis, OE | 1 |
| Funato, H; Hobara, T; Matsubara, T; Matsuo, K; Otsuki, K; Suetsugi, M; Uchida, S; Watanabe, Y | 1 |
| Barone, Y; Matrisciano, F; Modafferi, AM; Nicoletti, F; Pinna, G; Scaccianoce, S; Togna, GI | 1 |
| Gass, N; Lagus, M; Paunio, T; Porkka-Heiskanen, T; Saarela, J; Saharinen, J | 1 |
| Corda, MG; Giorgi, O; Piras, G | 1 |
| Andersen, SL; Greene-Colozzi, EA; Sonntag, KC | 1 |
| Banks, ML; Negus, SS; Rice, KC | 1 |
| Baez, A; Enders, JE; Fernández, AR; Fretes, R; Gea, S; Gobbi, P; Lo Presti, MS; Paglini-Oliva, PA; Rivarola, HW | 1 |
| Bhagya, V; Raju, TR; Rao, BS; Srikumar, BN | 1 |
| López-Rubalcava, C; Rogel-Salazar, G | 1 |
| Bult-Ito, A; Burrow, T; Castillo, MR; Foltz, H; Greene-Schloesser, DM; Gregg, KA; Sheppard, DK; Slater, M; Van der Zee, EA | 1 |
| Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS | 1 |
| Fukushima, K; Ito, Y; Kobuchi, S; Shibata, M; Sugioka, N; Takada, K | 1 |
| De Carolis, L; Milella, MS; Nencini, P; Schepisi, C | 1 |
| Dulawa, SC; Masten, VL; Shanahan, NA; Velez, LP | 1 |
| Feng, P; McDowell, AL; Strohl, KP | 1 |
| Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T | 1 |
| Dalla, C; Papadopoulou-Daifoti, Z; Pitychoutis, PM; Sideris, AC; Tsonis, PA | 1 |
| Castren, E; Porkka-Heiskanen, T; Rantamäki, T; Rytkönen, KM; Savelyev, SA | 1 |
| Santamaria-Cano, J | 1 |
| Gass, N; Lagus, M; Paunio, T; Porkka-Heiskanen, T; Saharinen, J; Savelyev, S | 1 |
| Huston, JP; Klingenhegel, I; Komorowski, M; Paulat, J; Sackers, J; Topic, B | 1 |
| Czurkó, A; Juhász, G; Kékesi, KA; Kovács, Z | 1 |
| Chen, T; Jia, W; Jia, Z; Jiang, T; Lin, J; Qiu, Y; Su, M; Wang, X; Xie, X; Zeng, C; Zhao, A; Zhao, T; Zhou, M | 1 |
| Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ | 1 |
| Coffman, CF; Fiacco, NR; Granger, JC; Helton, BM; Jackson, JC; Kim, LV; Kreiss, DS; Mistry, RS; Mizer, TM; Palmer, LV; Vacca, JA; Winkler, SS; Zimmer, BA | 1 |
| Bizup, B; Grace, AA; Sesia, T | 1 |
| Flügge, G; Fuchs, E; Hiemke, C; Kramer, M; van Kampen, M | 1 |
| Datta, S; Mavanji, V | 1 |
| Czéh, B; de Biurrun, G; Frahm, J; Fuchs, E; Michaelis, T; Natt, O; van der Hart, MG; Watanabe, T | 1 |
| Cabib, S; Puglisi-Allegra, S; Ventura, R | 1 |
| Chemelli, RM; Elmquist, JK; Hammer, RE; Kisanuki, YY; Kohlmeier, KA; Lee, C; Leonard, CS; Marcus, JN; Richardson, JA; Sinton, CM; Tokita, S; Williams, SC; Willie, JT; Yanagisawa, M | 1 |
| Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM | 1 |
| Bonilla-Jaime, H; Retana-Marquez, S; Vazquez-Palacios, G; Velázquez-Moctezuma, J | 1 |
| Fang, J; Feng, P; Guan, Z; Yang, X | 1 |
| Asakura, M; Fujii, S; Hishinumai, T; Kanai, S; Nagashima, H; Tanaka, D | 1 |
| Cordner, AP; Helmreich, DL; Herwood, MB; Parfitt, DB | 1 |
| Czéh, B; Flügge, G; Fuchs, E | 1 |
| Consoli, D; Drago, F; Fedotova, J; Micale, V; Sapronov, NS | 1 |
| de Lima, TC; de Oliveira, RM; del Bel, EA; Guimarães, FS; Lino-de-Oliveira, C; Pádua Carobrez, A | 1 |
| Cao, XD; Li, XY; Liu, Q; Wang, J; Wang, YQ; Wu, GC; Yu, J | 1 |
| Cao, XD; Li, XY; Wu, GC; Yu, J | 1 |
| Consoli, D; Drago, F; Leggio, GM; Mazzola, C; Micale, V | 1 |
| Hu, B; Xia, YH; Yang, LM; Zhang, BL; Zhao, H | 1 |
| Alkon, DL; Colombrita, C; Drago, F; Mazzola, C; Micale, V; Scapagnini, G | 1 |
| Adrien, J; Hamon, M; Maudhuit, C | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A | 1 |
| Rosenthal, MS; Vogel, GW | 1 |
| Neill, DB; Vogel, GW; Yavari, P | 1 |
| Gambarana, C; Ghiglieri, O; Graziella de Montis, M | 1 |
| Chavez-Chavez, L; Marvan, ML; Santana, S | 1 |
| Bartrons, R; Martínez-Gomis, J; Planas, ME; Planelles, X; Sánchez, S | 1 |
| Bonilla-Jaime, H; Retana-Marquez, S; Velazquez-Moctezuma, J | 1 |
| Eilam, D; Sulis, W; Szechtman, H | 1 |
| Karanth, KS; Kumar, KB; Prathiba, J | 1 |
| Meti, BL; Vijayakumar, M | 1 |
| Cardinali, DP; Gregoretti, L; Kargieman, L; Yannielli, PC | 1 |
| Ardid, D; Boucher, M; Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Méen, M | 1 |
| Arezzi, A; Drago, F; Virzì, A | 1 |
| Drago, F; Lo Menzo, G; Micale, V; Nicolosi, A | 1 |
| Okuyama, S; Takamori, K; Yoshida, S | 1 |
| Norrholm, SD; Ouimet, CC | 1 |
| Feng, P; Ma, Y | 1 |
| Kriete, M; Rapoport, JL; Ryland, DH | 1 |
| Diaz Ruiz, O; Velazquez-Moctezuma, J | 1 |
| Grindlinger, HM; Ramsay, E | 1 |
| Hagler, M; Hartley, P; Kors, D; Neill, D; Vogel, G | 2 |
| Hagler, M; Hennessey, A; Kors, D; Neill, D; Vogel, G | 1 |
| Hagler, M; Kors, D; Neill, D; Vogel, G | 1 |
| Rapoport, JL | 1 |
| Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B | 1 |
1 review(s) available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
[Diagnostic and therapeutic update in narcolepsy].
Topics: Adolescent; Adult; Age of Onset; Animals; Autoimmune Diseases; Benzhydryl Compounds; Cataplexy; Child; Clomipramine; Cyclohexanols; Delayed Diagnosis; Disease Models, Animal; Dogs; Genetic Predisposition to Disease; Histamine Agonists; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Hypothalamus; Immunoglobulins, Intravenous; Intracellular Signaling Peptides and Proteins; Methylphenidate; Modafinil; Narcolepsy; Neuropeptides; Orexins; Polysomnography; Receptors, Antigen, T-Cell; Sodium Oxybate; Venlafaxine Hydrochloride | 2012 |
1 trial(s) available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Double-Blind Method; Fenfluramine; Fluoxetine; Follow-Up Studies; Grooming; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Sertraline; Ulcer | 1992 |
94 other study(ies) available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Humans; Inflammasomes; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Stress, Psychological | 2022 |
Synergistic effects of
Topics: Animals; Clomipramine; Curcumin; Depression; Depressive Disorder; Disease Models, Animal; Glutamine; Humans; Infant; Lacticaseibacillus rhamnosus; Mice; Probiotics; Stress, Psychological | 2022 |
Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Brain-Derived Neurotrophic Factor; Catechin; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Interleukin-1beta; Mice; RNA, Messenger; Stress, Psychological; Tea | 2022 |
Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male t
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Male; Rats; Receptors, Glucocorticoid; Serotonin | 2023 |
Brain stimulation rewarding experience attenuates neonatal clomipramine-induced adulthood anxiety by reversal of pathological changes in the amygdala.
Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; Brain; Clomipramine; Corticosterone; Depression; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Female; Male; Pregnancy; Rats; Rats, Wistar; Reward; Self Stimulation | 2020 |
Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews.
Topics: Anhedonia; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Interpersonal Relations; Male; Motivation; Reward; Social Behavior; Tupaiidae | 2018 |
The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.
Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents, Tricyclic; Autophagy; Caenorhabditis elegans; Clomipramine; Disease Models, Animal; Liver; Mice; Neurons; Norepinephrine; Serotonin; Signal Transduction | 2019 |
Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats.
Topics: Animals; Antidepressive Agents; Clomipramine; Depression; Depressive Disorder; Disease Models, Animal; Locomotion; Male; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Stress, Psychological; Zinc | 2019 |
Phospholipase D-mTOR signaling is compromised in a rat model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain; Choline; Clomipramine; Depression; Disease Models, Animal; Down-Regulation; Male; Palmitates; Phospholipase D; Rats; Rats, Long-Evans; Selective Serotonin Reuptake Inhibitors; Sexual Behavior, Animal; Signal Transduction; TOR Serine-Threonine Kinases; Tritium | 2013 |
Clomipramine and benznidazole association for the treatment of acute experimental Trypanosoma cruzi infection.
Topics: Animals; Chagas Disease; Clomipramine; Disease Models, Animal; Drug Evaluation, Preclinical; Electrocardiography; Female; Intestines; Kidney; Liver; Male; Mice; Muscle, Skeletal; Myocardium; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi | 2013 |
Glucosylceramide and lysophosphatidylcholines as potential blood biomarkers for drug-induced hepatic phospholipidosis.
Topics: Amitriptyline; Animals; Bile Ducts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Clomipramine; Discriminant Analysis; Disease Models, Animal; Glucosylceramides; Hepatocytes; Imipramine; Least-Squares Analysis; Liver; Lysophosphatidylcholines; Lysosomal Storage Diseases; Male; Mass Spectrometry; Metabolomics; Multivariate Analysis; Predictive Value of Tests; Rats | 2014 |
The first observation of seasonal affective disorder symptoms in Rhesus macaque.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depression; Disease Models, Animal; Female; Hydrocortisone; Macaca mulatta; Motor Activity; Photoperiod; Seasonal Affective Disorder | 2015 |
Clomipramine and Benznidazole Act Synergistically and Ameliorate the Outcome of Experimental Chagas Disease.
Topics: Animals; Chagas Disease; Clomipramine; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Drug Synergism; Heart; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Parasitemia; Parasitic Sensitivity Tests; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi | 2016 |
Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessive-compulsive disorder induced by sensitization with d2/d3 agonist quinpirole.
Topics: Analysis of Variance; Animals; Avoidance Learning; Clomipramine; Disease Models, Animal; Dopamine Agonists; Electroshock; Escape Reaction; Hippocampus; Locomotion; Male; Maze Learning; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 2017 |
Effects of social stress and clomipramine on emotional memory in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clomipramine; Disease Models, Animal; Emotions; Inhibition, Psychological; Locomotion; Male; Maze Learning; Memory; Mice; Reaction Time; Stress, Psychological | 2016 |
Antidepressant-like effect of ethanol extract from Paeonia lactiflora in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Blepharoptosis; Clomipramine; Depression; Disease Models, Animal; Hindlimb Suspension; Hypothermia; Immobility Response, Tonic; Mice; Paeonia; Plant Extracts; Reserpine; Swimming | 2008 |
Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats.
Topics: Amino Acids; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Clomipramine; Colforsin; Cyclic AMP; Depression; Disease Models, Animal; Drug Interactions; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Methoxyhydroxyphenylglycol; Rats; Receptors, Metabotropic Glutamate; RNA, Messenger; Swimming | 2008 |
Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Benzodiazepines; Clomipramine; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Haloperidol; Male; Olanzapine; Piperazines; Pyrroles; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Thiazepines | 2008 |
Sex-related differential response to clomipramine treatment in a rat model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Disease Models, Animal; Female; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Serotonin; Sex Characteristics; Swimming | 2009 |
Correlation of plasma and peritoneal diasylate clomipramine concentration with hemodynamic recovery after intralipid infusion in rabbits.
Topics: Animals; Chromatography, High Pressure Liquid; Clomipramine; Dialysis Solutions; Disease Models, Animal; Fat Emulsions, Intravenous; Female; Hypotension; Infusions, Intravenous; Male; Peritoneal Dialysis; Rabbits | 2009 |
Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats.
Topics: Alveolar Bone Loss; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Disease Models, Animal; Male; Maxilla; Molar; Neuroimmunomodulation; Periodontitis; Random Allocation; Rats; Rats, Inbred Lew; Single-Blind Method | 2009 |
Clomipramine treatment reversed the glial pathology in a chronic unpredictable stress-induced rat model of depression.
Topics: Animals; Clomipramine; Depression; Disease Models, Animal; Exploratory Behavior; Freezing Reaction, Cataleptic; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Male; Neuroglia; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2009 |
Chronic antidepressant treatment exerts sexually dimorphic immunomodulatory effects in an experimental model of major depression: do females lack an advantage?
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Proliferation; Cells, Cultured; Chronic Disease; Clomipramine; Cytotoxicity, Immunologic; Depressive Disorder, Major; Disease Models, Animal; Dopamine; Drug Administration Schedule; Female; Immunity, Cellular; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Severity of Illness Index; Sex Characteristics; Sex Factors; Stress, Psychological; T-Lymphocytes; Thymus Gland | 2009 |
Altered gene expression of histone deacetylases in mood disorder patients.
Topics: Animals; Antidepressive Agents; Clomipramine; Corticotropin-Releasing Hormone; Dexamethasone; Disease Models, Animal; Female; Gene Expression Regulation; Histone Deacetylases; Humans; Hydrocortisone; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Mood Disorders; Paroxetine; RNA, Messenger; Swimming | 2010 |
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
Topics: Anabolic Agents; Androgens; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Clomipramine; Corticosterone; Depressive Disorder; Disease Models, Animal; Hypothalamo-Hypophyseal System; Male; Nandrolone; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stanozolol; Steroids; Substance-Related Disorders | 2010 |
Gene expression patterns in a rodent model for depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Female; Gene Expression; Male; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prosencephalon; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sleep Wake Disorders | 2010 |
Effects of antidepressants on the performance in the forced swim test of two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Clomipramine; Depression; Desipramine; Disease Models, Animal; Fluoxetine; Genetics, Behavioral; Phenotype; Rats; Rats, Inbred Strains; Stress, Psychological; Swimming | 2010 |
A novel, multiple symptom model of obsessive-compulsive-like behaviors in animals.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Corpus Striatum; Disease Models, Animal; Frontal Lobe; Male; Obsessive-Compulsive Disorder; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2 | 2010 |
Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Macaca mulatta; Male; Pain; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors | 2010 |
Association of clomipramine and allopurinol for the treatment of the experimental infection with Trypanosoma cruzi.
Topics: Allopurinol; Animals; Antibodies, Protozoan; Antigens, Protozoan; Antiprotozoal Agents; Chagas Disease; Clomipramine; Cysteine Endopeptidases; Disease Models, Animal; Drug Therapy, Combination; Electrocardiography; Male; Mice; Myocardium; Parasitemia; Protozoan Proteins; Survival Analysis; Treatment Outcome; Trypanosoma cruzi | 2010 |
Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Biogenic Monoamines; Citalopram; Clomipramine; Depression; Disease Models, Animal; Drug Administration Schedule; Feeding Behavior; Hippocampus; Learning; Long-Term Potentiation; Male; Maze Learning; Memory; Motor Activity; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Swimming; Time Factors | 2011 |
Evaluation of the anxiolytic-like effects of clomipramine in two rat strains with different anxiety vulnerability (Wistar and Wistar-Kyoto rats): participation of 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Male; Rats; Rats, Inbred WKY; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Species Specificity | 2011 |
Predictive validity of a non-induced mouse model of compulsive-like behavior.
Topics: Animals; Anxiety; Behavior, Animal; Clomipramine; Compulsive Behavior; Desipramine; Disease Models, Animal; Exploratory Behavior; Fluoxetine; Male; Maze Learning; Mice; Mice, Inbred Strains; Motor Activity; Nesting Behavior | 2011 |
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes | 2011 |
Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407-induced hyperlipidaemic model rats.
Topics: Animals; Antidepressive Agents; Blood-Brain Barrier; Brain; Clomipramine; Disease Models, Animal; Evans Blue; Hyperlipidemias; Lipoproteins; Male; Plasma; Poloxamer; Protein Binding; Rats; Rats, Wistar | 2011 |
Clomipramine, but not haloperidol or aripiprazole, inhibits quinpirole-induced water contrafreeloading, a putative animal model of compulsive behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Clomipramine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drinking Behavior; Haloperidol; Male; Piperazines; Quinolones; Quinpirole; Rats; Rats, Sprague-Dawley | 2011 |
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clomipramine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Female; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Iodocyanopindolol; Isotopes; Mice; Mice, Inbred BALB C; Neural Inhibition; Obsessive-Compulsive Disorder; Prefrontal Cortex; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Swimming; Time Factors | 2011 |
Sleep-related epilepsy in a Long-Evans hooded rat model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Disease Models, Animal; Electroencephalography; Epilepsy, Frontal Lobe; Fourier Analysis; Male; Motor Activity; Polysomnography; Rats; Rats, Long-Evans; Risk Factors; Sexual Behavior; Signal Processing, Computer-Assisted; Sleep Wake Disorders | 2012 |
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde; Hyperalgesia; Irritants; Male; Mice; Nociceptors; Orbit; Pruritus; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Tramadol; Transient Receptor Potential Channels; Trigeminal Nerve Injuries; Trigeminal Neuralgia; TRPA1 Cation Channel; TRPV Cation Channels; Vibrissae | 2011 |
5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Depression; Disease Models, Animal; Female; In Situ Hybridization; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Sex Characteristics; Stress, Psychological | 2012 |
Sleep homeostasis and depression: studies with the rat clomipramine model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Disease Models, Animal; Homeostasis; Male; Prosencephalon; Rats; Rats, Wistar; Sleep, REM | 2012 |
Inter-tissue networks between the basal forebrain, hippocampus, and prefrontal cortex in a model for depression caused by disturbed sleep.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Disease Models, Animal; Female; Food Preferences; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Hippocampus; Male; Neural Pathways; Oligonucleotide Array Sequence Analysis; Prefrontal Cortex; Prosencephalon; Rats; Rats, Wistar; Sleep Wake Disorders; Sucrose; Sweetening Agents | 2012 |
Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Clomipramine; Conditioning, Operant; Depressive Disorder, Major; Disease Models, Animal; Exploratory Behavior; Extinction, Psychological; Male; Rats; Rats, Wistar; Reaction Time; Reward; Time Factors | 2012 |
Neonatal tricyclic antidepressant clomipramine treatment reduces the spike-wave discharge activity of the adult WAG/Rij rat.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Choice Behavior; Clomipramine; Depressive Disorder, Major; Disease Models, Animal; Electroencephalography; Food Preferences; Male; Rats; Sleep, REM; Sucrose; Sweetening Agents; Time Factors; Wakefulness | 2012 |
Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Clomipramine; Depressive Disorder; Disease Models, Animal; Food Deprivation; Gas Chromatography-Mass Spectrometry; Ginsenosides; Hypericum; Male; Metabolome; Metabolomics; Multivariate Analysis; Phenotype; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Spleen; Stress, Psychological; Sucrose; Swimming; Thymus Gland | 2012 |
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease Models, Animal; Edema; Gentamicins; Heart Diseases; Heart Rate; Heart Ventricles; Larva; Microinjections; Nimodipine; Pericardium; Quinidine; Terfenadine; Tetracycline; Toxicity Tests; Verapamil; Yolk Sac; Zebrafish | 2014 |
Ritualistic chewing behavior induced by mCPP in the rat is an animal model of obsessive compulsive disorder.
Topics: Animals; Behavior, Animal; Clomipramine; Diazepam; Disease Models, Animal; Dopamine Antagonists; Fluvoxamine; GABA Modulators; Haloperidol; Male; Mastication; Mianserin; Obsessive-Compulsive Disorder; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 2013 |
Evaluation of animal models of obsessive-compulsive disorder: correlation with phasic dopamine neuron activity.
Topics: Action Potentials; Animals; Animals, Newborn; Clomipramine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Extinction, Psychological; Male; Maze Learning; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Ventral Tegmental Area | 2013 |
The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Disease Models, Animal; Humans; Male; Stress, Psychological; Tupaiidae | 2002 |
Sleep-wake effects of yohimbine and atropine in rats with a clomipramine-based model of depression.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Aggression; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Atropine; Brain; Brain Chemistry; Clomipramine; Depressive Disorder; Disease Models, Animal; Injections, Intraventricular; Male; Muscarinic Antagonists; Norepinephrine; Rats; Rats, Wistar; Reaction Time; Sleep Wake Disorders; Sleep, REM; Wakefulness; Yohimbine | 2002 |
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain Chemistry; Cell Division; Chronic Disease; Clomipramine; Dentate Gyrus; Depressive Disorder, Major; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Neurokinin-1 Receptor Antagonists; Stress, Psychological; Tupaiidae | 2002 |
Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral 'despair' in a mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Disease Models, Animal; Dopamine; Genetic Predisposition to Disease; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Stress, Physiological | 2002 |
Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
Topics: Animals; Arousal; Carrier Proteins; Cells, Cultured; Clomipramine; Disease Models, Animal; Efferent Pathways; Electroencephalography; Electromyography; Histamine; Hypothalamic Area, Lateral; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Narcolepsy; Neuropeptides; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Sleep, REM; Synaptic Transmission | 2003 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone | 2003 |
Corticosterone and testosterone levels after chronic stress in an animal model of depression.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Cold Temperature; Corticosterone; Depression; Disease Models, Animal; Female; Immobilization; Male; Pregnancy; Rats; Rats, Wistar; Stress, Physiological; Swimming; Testosterone; Time Factors | 2003 |
Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Blotting, Western; Brain; Clomipramine; Depression; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression; Male; Mitogen-Activated Protein Kinase 1; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Rats; Rats, Long-Evans; Sexual Behavior; Signal Transduction | 2003 |
[Effect of concurrent treatment of SSRI on the tyrosine hydroxylase immunoreactivity in the rat locus coeruleus treated with chronic variable stress].
Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Clomipramine; Corticotropin-Releasing Hormone; Disease Models, Animal; Fluvoxamine; Immunohistochemistry; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Antidepressants blunt the effects of inescapable stress on male mating behaviour and decrease corticotropin-releasing hormone mRNA expression in the hypothalamic paraventricular nucleus of the Syrian hamster (Mesocricetus auratus).
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clomipramine; Corticotropin-Releasing Hormone; Cricetinae; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Glucocorticoids; Male; Mesocricetus; Paraventricular Hypothalamic Nucleus; RNA, Messenger; Sexual Behavior, Animal; Stress, Psychological; Testosterone | 2004 |
Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cell Differentiation; Clomipramine; Depression; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Hypothalamo-Hypophyseal System; Male; Nerve Net; Neuronal Plasticity; Pituitary-Adrenal System; Stress, Psychological; Transcription, Genetic; Tupaiidae | 2004 |
Stressors affect the response of male and female rats to clomipramine in a model of behavioral despair (forced swim test).
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Corticosterone; Depression; Disease Models, Animal; Electroshock; Estrous Cycle; Female; Male; Rats; Rats, Wistar; Sex Factors; Stress, Physiological; Swimming | 2005 |
Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Cell Count; Clomipramine; Desipramine; Disease Models, Animal; Immobility Response, Tonic; Male; Oncogene Proteins v-fos; Periaqueductal Gray; Rats; Rats, Wistar; Stress, Psychological; Swimming | 2006 |
Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Electroacupuncture; Food Preferences; Male; Mice; Mice, Inbred Strains; Random Allocation; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming; Time Factors | 2007 |
Sucrose preference is restored by electro-acupuncture combined with chlorimipramine in the depression-model rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Combined Modality Therapy; Depression; Dietary Sucrose; Disease Models, Animal; Electroacupuncture; Food Preferences; Male; Rats; Rats, Sprague-Dawley; Sucrose; Treatment Outcome | 2006 |
Behavioral effects of the beta3 adrenoceptor agonist SR58611A: is it the putative prototype of a new class of antidepressant/anxiolytic drugs?
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Grooming; Injections, Intraperitoneal; Male; Maze Learning; Methysergide; Mice; Motor Activity; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3; Serotonin Antagonists; Swimming; Tetrahydronaphthalenes | 2007 |
Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus.
Topics: Animals; Antidepressive Agents; Chronic Disease; Clomipramine; Depressive Disorder; Disease Models, Animal; Habenula; Immobility Response, Tonic; Male; Neural Pathways; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Stress, Psychological | 2008 |
Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Behavior, Animal; Cholesterol, Dietary; Clomipramine; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Grooming; Immobility Response, Tonic; Isoquinolines; Male; Maze Learning; Rats; Rats, Wistar; Stress, Psychological; Swimming; Time Factors | 2008 |
Electrophysiological activity of raphe dorsalis serotoninergic neurones in a possible model of endogenous depression.
Topics: Animals; Antidepressive Agents; Citalopram; Clomipramine; Disease Models, Animal; Male; Membrane Potentials; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 1995 |
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder.
Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinking Behavior; Fluoxetine; Haloperidol; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors | 1993 |
The effects of a 3-day increase of ambient temperature on body temperature and REM sleep in an animal model of depression.
Topics: Acclimatization; Animals; Animals, Newborn; Body Temperature Regulation; Circadian Rhythm; Clomipramine; Depressive Disorder; Disease Models, Animal; Heating; Male; Rats; Rats, Sprague-Dawley; Sleep, REM | 1994 |
Decreased raphe unit activity in a rat model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Neurons; Raphe Nuclei; Rats; Serotonin; Sodium Chloride; Synaptic Transmission | 1993 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disease Models, Animal; Escape Reaction; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Time Factors | 1995 |
Clomipramine modifies fluctuations of forced swimming immobility in different phases of the rat estrous cycle.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Disease Models, Animal; Estrus; Female; Motor Activity; Physical Exertion; Rats; Rats, Wistar; Swimming | 1996 |
Fluoride and pilocarpine reduce the risk of caries produced by chronic clomipramine treatment in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Cariostatic Agents; Cholinergic Antagonists; Clomipramine; Dental Caries; Disease Models, Animal; Fluorides; Male; Pilocarpine; Rats; Rats, Wistar; Salivation; Statistics, Nonparametric; Xerostomia | 1997 |
Pharmacological features of masculine sexual behavior in an animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clomipramine; Depression; Disease Models, Animal; Humans; Male; Muscarinic Agonists; Oxotremorine; Rats; Rats, Wistar; Serotonin Receptor Agonists; Sexual Behavior, Animal; Yohimbine | 1998 |
Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD).
Topics: Animals; Clomipramine; Disease Models, Animal; Dopamine Agonists; Male; Obsessive-Compulsive Disorder; Orientation; Quinpirole; Rats; Rats, Long-Evans; Selective Serotonin Reuptake Inhibitors; Stereotyped Behavior | 1998 |
Hyperactivity of hypothalamic pituitary axis in neonatal clomipramine model of depression.
Topics: Animals; Animals, Newborn; Clomipramine; Depression; Depression, Chemical; Dexamethasone; Disease Models, Animal; Glucocorticoids; Hypothalamo-Hypophyseal System; Male; Rats; Rats, Wistar; Secretory Rate; Sleep, REM | 1998 |
Alterations in the levels of monoamines in discrete brain regions of clomipramine-induced animal model of endogenous depression.
Topics: Aggression; Animals; Biogenic Monoamines; Brain; Brain Stem; Clomipramine; Depression; Disease Models, Animal; Dopamine; Eating; Female; Frontal Lobe; Hippocampus; Hypothalamus; Male; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Septum Pellucidum; Serotonin | 1999 |
Effects of neonatal clomipramine treatment on locomotor activity, anxiety-related behavior and serotonin turnover in Syrian hamsters.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Clomipramine; Cricetinae; Disease Models, Animal; Hydroxyindoleacetic Acid; Mesocricetus; Motor Activity; Selective Serotonin Reuptake Inhibitors; Serotonin | 1999 |
Potentiation of morphine and clomipramine analgesia by cholecystokinin -B antagonist CI-988 in diabetic rats.
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomipramine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Meglumine; Morphine; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors | 2000 |
Effects of acute or chronic administration of substituted benzamides in experimental models of depression in rats.
Topics: Animals; Antidepressive Agents; Benzamides; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Raclopride; Rats; Rats, Wistar; Sulpiride | 2000 |
Placebo affects the performance of rats in models of depression: is it a good control for behavioral experiments?
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Placebo Effect; Rats; Rats, Wistar | 2001 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Mianserin; Motor Activity; Rats; Rats, Wistar; Swimming | 2001 |
Altered dendritic spine density in animal models of depression and in response to antidepressant treatment.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Dendrites; Denervation; Depression; Disease Models, Animal; Male; Maternal Deprivation; Neuronal Plasticity; Olfactory Bulb; Rats; Rats, Sprague-Dawley | 2001 |
Clomipramine suppresses postnatal REM sleep without increasing wakefulness: implications for the production of depressive behaviors.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Electrodes, Implanted; Polysomnography; Rats; Rats, Long-Evans; Sleep, REM; Wakefulness | 2002 |
Neonatal treatment with clomipramine increased immobility in the forced swim test: an attribute of animal models of depression.
Topics: Animals; Animals, Newborn; Clomipramine; Defecation; Depressive Disorder; Disease Models, Animal; Male; Motor Activity; Rats; Rats, Inbred Strains; Swimming | 1992 |
Compulsive feather picking in birds.
Topics: Animals; Animals, Domestic; Bird Diseases; Clomipramine; Disease Models, Animal; Female; Humans; Male; Obsessive-Compulsive Disorder; Psittaciformes | 1991 |
Procedure- and age-dependent hyperactivity in a new animal model of endogenous depression.
Topics: Aging; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Disease Models, Animal; Hyperkinesis; Male; Rats; Rats, Inbred Strains; Stress, Psychological | 1990 |
Diminished sexual activity in a new animal model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Species Specificity | 1990 |
REM sleep abnormalities in a new animal model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Male; Rats; Rats, Inbred Strains; Sleep Wake Disorders; Sleep, REM | 1990 |
Treatment of behavioral disorders in animals.
Topics: Animal Diseases; Animals; Animals, Domestic; Clomipramine; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Mental Disorders | 1990 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep | 1987 |
Animal depression model by neonatal clomipramine: reduction of shock induced aggression.
Topics: Age Factors; Aggression; Animals; Animals, Newborn; Clomipramine; Depression; Disease Models, Animal; Female; Pregnancy; Rats; Rats, Inbred Strains; Sleep, REM | 1988 |