clomipramine has been researched along with Disease Models, Animal in 96 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After oral treatment with clomipramine (50 mg/kg/day) for four weeks, most of the depression-like behaviors were reversed, whereas the motivational reduction was not clearly affected." | 7.88 | Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews. ( Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N, 2018) |
| "Quinpirole (QNP) sensitization is one of the commonly used animal models of obsessive-compulsive disorder (OCD)." | 7.85 | Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessive-compulsive disorder induced by sensitization with d2/d3 agonist quinpirole. ( Hatalova, H; Pistikova, A; Radostova, D; Stuchlik, A; Vales, K, 2017) |
| "This study examined the integrity of hypothalamic-pituitary-adrenal (HPA) axis in clomipramine model of depression." | 7.70 | Hyperactivity of hypothalamic pituitary axis in neonatal clomipramine model of depression. ( Karanth, KS; Kumar, KB; Prathiba, J, 1998) |
| "Day-night differences in locomotor and anxiety-related behavior and brain serotonin metabolism were examined in adult Syrian hamsters that received clomipramine (15 mg/kg) or vehicle from day 8 to day 21 of life." | 7.70 | Effects of neonatal clomipramine treatment on locomotor activity, anxiety-related behavior and serotonin turnover in Syrian hamsters. ( Cardinali, DP; Gregoretti, L; Kargieman, L; Yannielli, PC, 1999) |
| "Chagas disease is an important public health problem in Latin America, and its treatment by chemotherapy with benznidazole (BZ) or nifurtimox remains unsatisfactory." | 5.43 | Clomipramine and Benznidazole Act Synergistically and Ameliorate the Outcome of Experimental Chagas Disease. ( Aoki, MP; García, MC; Jimenez-Kairuz, AF; Manzo, RH; Ponce, NE; Sanmarco, LM, 2016) |
| "In teeth with ligature, mean alveolar bone loss varied from 0." | 5.35 | Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats. ( Gaio, EJ; Rosing, CK; Soletti, AC, 2009) |
| "The present study was to investigate the effect of electroacupuncture (EA) combined with chlorimipramine on the sucrose preference of depressive rats induced by chronic mild stress (CMS)." | 5.33 | Sucrose preference is restored by electro-acupuncture combined with chlorimipramine in the depression-model rats. ( Cao, XD; Li, XY; Wu, GC; Yu, J, 2006) |
| "Depression is associated with deficiencies in monoaminergic transmitters and possibly neurotrophins." | 5.32 | Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine. ( Fang, J; Feng, P; Guan, Z; Yang, X, 2003) |
| " After oral treatment with clomipramine (50 mg/kg/day) for four weeks, most of the depression-like behaviors were reversed, whereas the motivational reduction was not clearly affected." | 3.88 | Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews. ( Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N, 2018) |
| "Quinpirole (QNP) sensitization is one of the commonly used animal models of obsessive-compulsive disorder (OCD)." | 3.85 | Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessive-compulsive disorder induced by sensitization with d2/d3 agonist quinpirole. ( Hatalova, H; Pistikova, A; Radostova, D; Stuchlik, A; Vales, K, 2017) |
| " In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis." | 3.80 | Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014) |
| " During and at the end point of the chronic stress experiment, food consumption, body weight, adrenal gland, thymus and spleen indices, behavior scores, sucrose consumption, and stress hormone levels were measured." | 3.78 | Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression. ( Chen, T; Jia, W; Jia, Z; Jiang, T; Lin, J; Qiu, Y; Su, M; Wang, X; Xie, X; Zeng, C; Zhao, A; Zhao, T; Zhou, M, 2012) |
| "To develop a behavioral model in mice that is capable of mimicking some distinctive symptoms of human posttraumatic trigeminal neuropathic pain such as spontaneous pain, cold allodynia, and chemical÷inflammatory hyperalgesia, and to use this model to investigate the antinociceptive effects of clomipramine and tramadol, two drugs used for the treatment of neuropathic pain." | 3.77 | Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice. ( Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T, 2011) |
| " The authors set out to document plasma and peritoneal diasylate clomipramine concentration after resuscitation with lipid emulsion in a rabbit model of clomipramine-induced hypotension." | 3.75 | Correlation of plasma and peritoneal diasylate clomipramine concentration with hemodynamic recovery after intralipid infusion in rabbits. ( Cave, G; Harvey, M; Hoggett, K, 2009) |
| "The present study was designed to evaluate the antidepressant effect of electroacupuncture (EA) and the potential additive or synergistic effects of EA and clomipramine (CLO, a tricyclic antidepressant) in the mouse forced swimming test (FST) and chronic mild stress (CMS) induced depression-model rats." | 3.74 | Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents. ( Cao, XD; Li, XY; Liu, Q; Wang, J; Wang, YQ; Wu, GC; Yu, J, 2007) |
| " To examine these novel concepts of the pathophysiology of depression and antidepressant medication we have carried out a series of experiments using the chronic psychosocial stress paradigm in male tree shrews, an animal model with a high validity for the pathophysiology of depressive disorders, in which the animals were treated with the tricyclic antidepressant compound clomipramine." | 3.72 | Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews. ( Czéh, B; Flügge, G; Fuchs, E, 2004) |
| " The non-selective noradrenaline (NA) and serotonin (5-HT) reuptake inhibitors imipramine, amitriptyline and clomipramine displayed anti-inflammatory activity in the carrageenan model of paw inflammation." | 3.72 | Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat. ( Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM, 2003) |
| "Olfactory bulbectomy, neonatal clomipramine administration, and maternal deprivation have been employed as animal models of depression." | 3.71 | Altered dendritic spine density in animal models of depression and in response to antidepressant treatment. ( Norrholm, SD; Ouimet, CC, 2001) |
| "Clomipramine (CLI), a REM sleep suppressant, alleviates symptoms of depression in adults but produces depressive behaviors if applied neonatally." | 3.71 | Clomipramine suppresses postnatal REM sleep without increasing wakefulness: implications for the production of depressive behaviors. ( Feng, P; Ma, Y, 2002) |
| "This study examined the integrity of hypothalamic-pituitary-adrenal (HPA) axis in clomipramine model of depression." | 3.70 | Hyperactivity of hypothalamic pituitary axis in neonatal clomipramine model of depression. ( Karanth, KS; Kumar, KB; Prathiba, J, 1998) |
| "Neonatal treatment with clomipramine induces behavioral alterations during adulthood that resemble symptoms observed in human depression." | 3.70 | Pharmacological features of masculine sexual behavior in an animal model of depression. ( Bonilla-Jaime, H; Retana-Marquez, S; Velazquez-Moctezuma, J, 1998) |
| "Day-night differences in locomotor and anxiety-related behavior and brain serotonin metabolism were examined in adult Syrian hamsters that received clomipramine (15 mg/kg) or vehicle from day 8 to day 21 of life." | 3.70 | Effects of neonatal clomipramine treatment on locomotor activity, anxiety-related behavior and serotonin turnover in Syrian hamsters. ( Cardinali, DP; Gregoretti, L; Kargieman, L; Yannielli, PC, 1999) |
| "The effects of substituted benzamides, sulpiride and raclopride on experimental models of depression were studied in male rats after acute or chronic administration in comparison to those of the classical antidepressant, clomipramine." | 3.70 | Effects of acute or chronic administration of substituted benzamides in experimental models of depression in rats. ( Arezzi, A; Drago, F; Virzì, A, 2000) |
| "Canine acral lick dermatitis is a naturally occurring disorder in which excessive licking of paws or flank can produce ulcers and infection that require medical treatment." | 2.67 | Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder. ( Kriete, M; Rapoport, JL; Ryland, DH, 1992) |
| "Narcolepsy is an emblematic, unique disease within sleep disorders that is characterised by excessive daytime sleepiness, cataplexy and other abnormal manifestations of REM sleep." | 2.48 | [Diagnostic and therapeutic update in narcolepsy]. ( Santamaria-Cano, J, 2012) |
| "In addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-HT1A, 5-HT2A, and 5-HT3 in brain regions that regulate mood, emotions, and memory, such as the prefrontal cortex, hippocampus, and amygdala." | 1.91 | Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male t ( Arteaga-Silva, M; Bonilla-Jaime, H; Cerbón, M; Limón-Morales, O; Molina-Jiménez, T; Morales-Quintero, K, 2023) |
| "Depression is a common mental disease affecting a lot of people of all ages around the world." | 1.51 | Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats. ( Abdelmelek, H; Ammari, M; Lassoued, A; Othman, H; Sakly, M, 2019) |
| "Chagas disease is an important public health problem in Latin America, and its treatment by chemotherapy with benznidazole (BZ) or nifurtimox remains unsatisfactory." | 1.43 | Clomipramine and Benznidazole Act Synergistically and Ameliorate the Outcome of Experimental Chagas Disease. ( Aoki, MP; García, MC; Jimenez-Kairuz, AF; Manzo, RH; Ponce, NE; Sanmarco, LM, 2016) |
| "Depression is associated with structural and neurochemical changes in limbic structures, including the hippocampus, that control emotion and mood." | 1.39 | Phospholipase D-mTOR signaling is compromised in a rat model of depression. ( Feng, P; Huang, C, 2013) |
| " Results of this study provide useful information for dosage adjustment of clomipramine in hyperlipidaemia." | 1.37 | Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407-induced hyperlipidaemic model rats. ( Fukushima, K; Ito, Y; Kobuchi, S; Shibata, M; Sugioka, N; Takada, K, 2011) |
| "Abolition of mechanical hyperalgesia was observed in mononeuropathic rats after five injections of clomipramine (5 mg·kg(-1) , s." | 1.37 | Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain? ( Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS, 2011) |
| "Clomipramine was inactive alone and did not alter the effects of mu agonists." | 1.36 | Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy. ( Banks, ML; Negus, SS; Rice, KC, 2010) |
| "In teeth with ligature, mean alveolar bone loss varied from 0." | 1.35 | Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats. ( Gaio, EJ; Rosing, CK; Soletti, AC, 2009) |
| "The present study was to investigate the effect of electroacupuncture (EA) combined with chlorimipramine on the sucrose preference of depressive rats induced by chronic mild stress (CMS)." | 1.33 | Sucrose preference is restored by electro-acupuncture combined with chlorimipramine in the depression-model rats. ( Cao, XD; Li, XY; Wu, GC; Yu, J, 2006) |
| "Depression is associated with deficiencies in monoaminergic transmitters and possibly neurotrophins." | 1.32 | Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine. ( Fang, J; Feng, P; Guan, Z; Yang, X, 2003) |
| "Because human endogenous depression is associated with abnormal REM sleep and an elevated nocturnal Tb, these results give further support for the validity of the CLI model of depression and provide insight into the relationships among Tb, Ta, REM sleep and depression." | 1.29 | The effects of a 3-day increase of ambient temperature on body temperature and REM sleep in an animal model of depression. ( Rosenthal, MS; Vogel, GW, 1994) |
| "One theory about the pathogenesis of endogenous depression is that decreased serotonergic (5-HT) neurotransmission is involved in producing the disorder." | 1.29 | Decreased raphe unit activity in a rat model of endogenous depression. ( Neill, DB; Vogel, GW; Yavari, P, 1993) |
| " Moreover, long term administration of both imipramine or SKF 38393 down regulated D1 dopamine receptor number in the prefrontal cortex, while the association of the two drugs resulted in a receptor density similar to that of control rats." | 1.29 | Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine. ( Gambarana, C; Ghiglieri, O; Graziella de Montis, M, 1995) |
| " Chronic administration of the selective serotonin re-uptake inhibitors fluoxetine and clomipramine (CMI) at 5 mg/kg per day and fluvoxamine at 10 mg/kg twice a day significantly decreased schedule-induced polydipsia (SIP) on day 15 and throughout the remainder of the study compared to control rats." | 1.29 | Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder. ( Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A, 1993) |
| "This suggests that an animal model of endogenous depression should show diminished sexual activity." | 1.28 | Diminished sexual activity in a new animal model of endogenous depression. ( Hagler, M; Hennessey, A; Kors, D; Neill, D; Vogel, G, 1990) |
| "Fengabine (SL 79." | 1.27 | Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. ( Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.08) | 18.7374 |
| 1990's | 19 (19.79) | 18.2507 |
| 2000's | 32 (33.33) | 29.6817 |
| 2010's | 37 (38.54) | 24.3611 |
| 2020's | 6 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 2 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Zhang, S | 1 |
| Hu, J | 1 |
| Liu, G | 1 |
| Wu, H | 1 |
| Li, M | 2 |
| Shi, C | 1 |
| Liu, Q | 3 |
| Faucher, P | 1 |
| Dries, A | 1 |
| Mousset, PY | 1 |
| Leboyer, M | 1 |
| Dore, J | 1 |
| Beracochea, D | 1 |
| Abdelmeguid, NE | 1 |
| Hammad, TM | 1 |
| Abdel-Moneim, AM | 1 |
| Salam, SA | 1 |
| Limón-Morales, O | 1 |
| Morales-Quintero, K | 1 |
| Arteaga-Silva, M | 1 |
| Molina-Jiménez, T | 1 |
| Cerbón, M | 1 |
| Bonilla-Jaime, H | 3 |
| Chakraborty, S | 1 |
| Tripathi, SJ | 1 |
| Raju, TR | 2 |
| Shankaranarayana Rao, BS | 1 |
| Shen, F | 1 |
| Qi, K | 1 |
| Duan, Y | 1 |
| Li, Y | 1 |
| Liang, J | 1 |
| Meng, X | 1 |
| Sui, N | 1 |
| Cavaliere, F | 1 |
| Fornarelli, A | 1 |
| Bertan, F | 1 |
| Russo, R | 1 |
| Marsal-Cots, A | 1 |
| Morrone, LA | 1 |
| Adornetto, A | 1 |
| Corasaniti, MT | 1 |
| Bano, D | 1 |
| Bagetta, G | 1 |
| Nicotera, P | 1 |
| Othman, H | 1 |
| Ammari, M | 1 |
| Lassoued, A | 1 |
| Sakly, M | 1 |
| Abdelmelek, H | 1 |
| Feng, P | 4 |
| Huang, C | 1 |
| Strauss, M | 1 |
| Lo Presti, MS | 2 |
| Bazán, PC | 1 |
| Baez, A | 2 |
| Fauro, R | 1 |
| Esteves, B | 1 |
| Sanchez Negrete, O | 1 |
| Cremonezzi, D | 1 |
| Paglini-Oliva, PA | 2 |
| Rivarola, HW | 2 |
| Saito, K | 1 |
| Maekawa, K | 1 |
| Ishikawa, M | 1 |
| Senoo, Y | 1 |
| Urata, M | 1 |
| Murayama, M | 1 |
| Nakatsu, N | 1 |
| Yamada, H | 1 |
| Saito, Y | 1 |
| Qin, D | 1 |
| Chu, X | 1 |
| Feng, X | 1 |
| Li, Z | 1 |
| Yang, S | 1 |
| Lü, L | 1 |
| Yang, Q | 1 |
| Pan, L | 1 |
| Yin, Y | 1 |
| Li, J | 1 |
| Xu, L | 1 |
| Chen, L | 1 |
| Hu, X | 1 |
| García, MC | 1 |
| Ponce, NE | 1 |
| Sanmarco, LM | 1 |
| Manzo, RH | 1 |
| Jimenez-Kairuz, AF | 1 |
| Aoki, MP | 1 |
| Hatalova, H | 1 |
| Radostova, D | 1 |
| Pistikova, A | 1 |
| Vales, K | 1 |
| Stuchlik, A | 1 |
| Duque, A | 1 |
| Vinader-Caerols, C | 1 |
| Monleón, S | 1 |
| Mao, Q | 1 |
| Huang, Z | 1 |
| Ip, S | 1 |
| Che, C | 1 |
| Matrisciano, F | 2 |
| Caruso, A | 1 |
| Orlando, R | 1 |
| Marchiafava, M | 1 |
| Bruno, V | 1 |
| Battaglia, G | 1 |
| Gruber, SH | 1 |
| Melchiorri, D | 1 |
| Tatarelli, R | 1 |
| Girardi, P | 1 |
| Mathè, AA | 1 |
| Nicoletti, F | 2 |
| Amato, D | 1 |
| Stasi, MA | 1 |
| Borsini, F | 1 |
| Nencini, P | 2 |
| Kokras, N | 1 |
| Antoniou, K | 1 |
| Dalla, C | 2 |
| Bekris, S | 1 |
| Xagoraris, M | 1 |
| Ovestreet, DH | 1 |
| Papadopoulou-Daifoti, Z | 3 |
| Harvey, M | 1 |
| Cave, G | 1 |
| Hoggett, K | 1 |
| Soletti, AC | 1 |
| Gaio, EJ | 1 |
| Rosing, CK | 1 |
| Li, B | 1 |
| Zhu, HY | 1 |
| Wang, YQ | 2 |
| Yu, J | 3 |
| Wu, GC | 3 |
| Pitychoutis, PM | 2 |
| Griva, E | 1 |
| Ioannou, K | 1 |
| Tsitsilonis, OE | 1 |
| Hobara, T | 1 |
| Uchida, S | 1 |
| Otsuki, K | 1 |
| Matsubara, T | 1 |
| Funato, H | 1 |
| Matsuo, K | 1 |
| Suetsugi, M | 1 |
| Watanabe, Y | 1 |
| Modafferi, AM | 1 |
| Togna, GI | 1 |
| Barone, Y | 1 |
| Pinna, G | 1 |
| Scaccianoce, S | 1 |
| Lagus, M | 2 |
| Gass, N | 2 |
| Saharinen, J | 2 |
| Saarela, J | 1 |
| Porkka-Heiskanen, T | 3 |
| Paunio, T | 2 |
| Piras, G | 1 |
| Giorgi, O | 1 |
| Corda, MG | 1 |
| Andersen, SL | 1 |
| Greene-Colozzi, EA | 1 |
| Sonntag, KC | 1 |
| Banks, ML | 1 |
| Rice, KC | 1 |
| Negus, SS | 1 |
| Gobbi, P | 1 |
| Fernández, AR | 1 |
| Enders, JE | 1 |
| Fretes, R | 1 |
| Gea, S | 1 |
| Bhagya, V | 1 |
| Srikumar, BN | 1 |
| Rao, BS | 1 |
| Rogel-Salazar, G | 1 |
| López-Rubalcava, C | 1 |
| Greene-Schloesser, DM | 1 |
| Van der Zee, EA | 1 |
| Sheppard, DK | 1 |
| Castillo, MR | 1 |
| Gregg, KA | 1 |
| Burrow, T | 1 |
| Foltz, H | 1 |
| Slater, M | 1 |
| Bult-Ito, A | 1 |
| Wattiez, AS | 1 |
| Libert, F | 1 |
| Privat, AM | 1 |
| Loiodice, S | 1 |
| Fialip, J | 2 |
| Eschalier, A | 2 |
| Courteix, C | 2 |
| Kobuchi, S | 1 |
| Fukushima, K | 1 |
| Shibata, M | 1 |
| Ito, Y | 1 |
| Sugioka, N | 1 |
| Takada, K | 1 |
| De Carolis, L | 1 |
| Schepisi, C | 1 |
| Milella, MS | 1 |
| Shanahan, NA | 1 |
| Velez, LP | 1 |
| Masten, VL | 1 |
| Dulawa, SC | 1 |
| McDowell, AL | 1 |
| Strohl, KP | 1 |
| Alvarez, P | 1 |
| Brun, A | 1 |
| Labertrandie, A | 1 |
| Lopez, J | 1 |
| Correa, A | 1 |
| Constandil, L | 1 |
| Hernández, A | 1 |
| Pelissier, T | 1 |
| Sideris, AC | 1 |
| Tsonis, PA | 1 |
| Savelyev, SA | 1 |
| Rantamäki, T | 1 |
| Rytkönen, KM | 1 |
| Castren, E | 1 |
| Santamaria-Cano, J | 1 |
| Savelyev, S | 1 |
| Komorowski, M | 1 |
| Huston, JP | 1 |
| Klingenhegel, I | 1 |
| Paulat, J | 1 |
| Sackers, J | 1 |
| Topic, B | 1 |
| Kovács, Z | 1 |
| Czurkó, A | 1 |
| Kékesi, KA | 1 |
| Juhász, G | 1 |
| Wang, X | 1 |
| Zeng, C | 1 |
| Lin, J | 1 |
| Chen, T | 1 |
| Zhao, T | 1 |
| Jia, Z | 1 |
| Xie, X | 1 |
| Qiu, Y | 1 |
| Su, M | 1 |
| Jiang, T | 1 |
| Zhou, M | 1 |
| Zhao, A | 1 |
| Jia, W | 1 |
| Zhu, JJ | 1 |
| Xu, YQ | 1 |
| He, JH | 1 |
| Yu, HP | 1 |
| Huang, CJ | 1 |
| Gao, JM | 1 |
| Dong, QX | 1 |
| Xuan, YX | 1 |
| Li, CQ | 1 |
| Kreiss, DS | 1 |
| Coffman, CF | 1 |
| Fiacco, NR | 1 |
| Granger, JC | 1 |
| Helton, BM | 1 |
| Jackson, JC | 1 |
| Kim, LV | 1 |
| Mistry, RS | 1 |
| Mizer, TM | 1 |
| Palmer, LV | 1 |
| Vacca, JA | 1 |
| Winkler, SS | 1 |
| Zimmer, BA | 1 |
| Sesia, T | 1 |
| Bizup, B | 1 |
| Grace, AA | 1 |
| van Kampen, M | 1 |
| Kramer, M | 1 |
| Hiemke, C | 1 |
| Flügge, G | 2 |
| Fuchs, E | 3 |
| Mavanji, V | 1 |
| Datta, S | 1 |
| van der Hart, MG | 1 |
| Czéh, B | 2 |
| de Biurrun, G | 1 |
| Michaelis, T | 1 |
| Watanabe, T | 1 |
| Natt, O | 1 |
| Frahm, J | 1 |
| Ventura, R | 1 |
| Cabib, S | 1 |
| Puglisi-Allegra, S | 1 |
| Willie, JT | 1 |
| Chemelli, RM | 1 |
| Sinton, CM | 1 |
| Tokita, S | 1 |
| Williams, SC | 1 |
| Kisanuki, YY | 1 |
| Marcus, JN | 1 |
| Lee, C | 1 |
| Elmquist, JK | 1 |
| Kohlmeier, KA | 1 |
| Leonard, CS | 1 |
| Richardson, JA | 1 |
| Hammer, RE | 1 |
| Yanagisawa, M | 1 |
| Abdel-Salam, OM | 1 |
| Nofal, SM | 1 |
| El-Shenawy, SM | 1 |
| Retana-Marquez, S | 2 |
| Vazquez-Palacios, G | 1 |
| Velázquez-Moctezuma, J | 3 |
| Guan, Z | 1 |
| Yang, X | 1 |
| Fang, J | 1 |
| Fujii, S | 1 |
| Asakura, M | 1 |
| Kanai, S | 1 |
| Tanaka, D | 1 |
| Hishinumai, T | 1 |
| Nagashima, H | 1 |
| Cordner, AP | 1 |
| Herwood, MB | 1 |
| Helmreich, DL | 1 |
| Parfitt, DB | 1 |
| Consoli, D | 2 |
| Fedotova, J | 1 |
| Micale, V | 4 |
| Sapronov, NS | 1 |
| Drago, F | 5 |
| Lino-de-Oliveira, C | 1 |
| de Oliveira, RM | 1 |
| Pádua Carobrez, A | 1 |
| de Lima, TC | 1 |
| del Bel, EA | 1 |
| Guimarães, FS | 1 |
| Wang, J | 1 |
| Li, XY | 2 |
| Cao, XD | 2 |
| Leggio, GM | 1 |
| Mazzola, C | 2 |
| Yang, LM | 1 |
| Hu, B | 1 |
| Xia, YH | 1 |
| Zhang, BL | 1 |
| Zhao, H | 1 |
| Scapagnini, G | 1 |
| Colombrita, C | 1 |
| Alkon, DL | 1 |
| Maudhuit, C | 1 |
| Hamon, M | 1 |
| Adrien, J | 1 |
| Woods, A | 1 |
| Smith, C | 1 |
| Szewczak, M | 1 |
| Dunn, RW | 1 |
| Cornfeldt, M | 1 |
| Corbett, R | 1 |
| Rosenthal, MS | 1 |
| Vogel, GW | 2 |
| Yavari, P | 1 |
| Neill, DB | 1 |
| Gambarana, C | 1 |
| Ghiglieri, O | 1 |
| Graziella de Montis, M | 1 |
| Marvan, ML | 1 |
| Chavez-Chavez, L | 1 |
| Santana, S | 1 |
| Martínez-Gomis, J | 1 |
| Planas, ME | 1 |
| Planelles, X | 1 |
| Bartrons, R | 1 |
| Sánchez, S | 1 |
| Szechtman, H | 1 |
| Sulis, W | 1 |
| Eilam, D | 1 |
| Prathiba, J | 1 |
| Kumar, KB | 1 |
| Karanth, KS | 1 |
| Vijayakumar, M | 1 |
| Meti, BL | 1 |
| Yannielli, PC | 1 |
| Kargieman, L | 1 |
| Gregoretti, L | 1 |
| Cardinali, DP | 1 |
| Coudoré-Civiale, MA | 1 |
| Boucher, M | 1 |
| Méen, M | 1 |
| Ardid, D | 1 |
| Arezzi, A | 1 |
| Virzì, A | 1 |
| Nicolosi, A | 1 |
| Lo Menzo, G | 1 |
| Takamori, K | 1 |
| Yoshida, S | 1 |
| Okuyama, S | 1 |
| Norrholm, SD | 1 |
| Ouimet, CC | 1 |
| Ma, Y | 1 |
| Rapoport, JL | 2 |
| Ryland, DH | 1 |
| Kriete, M | 1 |
| Diaz Ruiz, O | 1 |
| Grindlinger, HM | 1 |
| Ramsay, E | 1 |
| Hartley, P | 2 |
| Neill, D | 4 |
| Hagler, M | 4 |
| Kors, D | 4 |
| Vogel, G | 4 |
| Hennessey, A | 1 |
| Lloyd, KG | 1 |
| Zivkovic, B | 1 |
| Sanger, D | 1 |
| Depoortere, H | 1 |
| Bartholini, G | 1 |
1 review available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
[Diagnostic and therapeutic update in narcolepsy].
Topics: Adolescent; Adult; Age of Onset; Animals; Autoimmune Diseases; Benzhydryl Compounds; Cataplexy; Chil | 2012 |
1 trial available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Disease | 1992 |
94 other studies available for clomipramine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Human | 2022 |
Synergistic effects of
Topics: Animals; Clomipramine; Curcumin; Depression; Depressive Disorder; Disease Models, Animal; Glutamine; | 2022 |
Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Brain-Derived Neurot | 2022 |
Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male t
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Clomipramine; Depression; Disease Models, Animal; | 2023 |
Brain stimulation rewarding experience attenuates neonatal clomipramine-induced adulthood anxiety by reversal of pathological changes in the amygdala.
Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; | 2020 |
Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews.
Topics: Anhedonia; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Di | 2018 |
The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.
Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents, Tricyclic; Autophagy; Caenorhabditis | 2019 |
Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats.
Topics: Animals; Antidepressive Agents; Clomipramine; Depression; Depressive Disorder; Disease Models, Anima | 2019 |
Phospholipase D-mTOR signaling is compromised in a rat model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain; Choline; Clomipramine; Depressio | 2013 |
Clomipramine and benznidazole association for the treatment of acute experimental Trypanosoma cruzi infection.
Topics: Animals; Chagas Disease; Clomipramine; Disease Models, Animal; Drug Evaluation, Preclinical; Electro | 2013 |
Glucosylceramide and lysophosphatidylcholines as potential blood biomarkers for drug-induced hepatic phospholipidosis.
Topics: Amitriptyline; Animals; Bile Ducts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatograp | 2014 |
The first observation of seasonal affective disorder symptoms in Rhesus macaque.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depression; Disease Models, An | 2015 |
Clomipramine and Benznidazole Act Synergistically and Ameliorate the Outcome of Experimental Chagas Disease.
Topics: Animals; Chagas Disease; Clomipramine; Disease Models, Animal; Drug Administration Schedule; Drug Co | 2016 |
Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessive-compulsive disorder induced by sensitization with d2/d3 agonist quinpirole.
Topics: Analysis of Variance; Animals; Avoidance Learning; Clomipramine; Disease Models, Animal; Dopamine Ag | 2017 |
Effects of social stress and clomipramine on emotional memory in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clomipramine; D | 2016 |
Antidepressant-like effect of ethanol extract from Paeonia lactiflora in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Blepharoptosis; Clomipramine; Depression; Dise | 2008 |
Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats.
Topics: Amino Acids; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bridged Bicyclo Compounds, | 2008 |
Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Benzodiazepines; Clomipramine; Clozapine; Disea | 2008 |
Sex-related differential response to clomipramine treatment in a rat model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Disease Models, Animal; Female; | 2009 |
Correlation of plasma and peritoneal diasylate clomipramine concentration with hemodynamic recovery after intralipid infusion in rabbits.
Topics: Animals; Chromatography, High Pressure Liquid; Clomipramine; Dialysis Solutions; Disease Models, Ani | 2009 |
Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats.
Topics: Alveolar Bone Loss; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; C | 2009 |
Clomipramine treatment reversed the glial pathology in a chronic unpredictable stress-induced rat model of depression.
Topics: Animals; Clomipramine; Depression; Disease Models, Animal; Exploratory Behavior; Freezing Reaction, | 2009 |
Chronic antidepressant treatment exerts sexually dimorphic immunomodulatory effects in an experimental model of major depression: do females lack an advantage?
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Proliferation; Cells, Cultured; Chronic Disease; Clo | 2009 |
Altered gene expression of histone deacetylases in mood disorder patients.
Topics: Animals; Antidepressive Agents; Clomipramine; Corticotropin-Releasing Hormone; Dexamethasone; Diseas | 2010 |
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
Topics: Anabolic Agents; Androgens; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brai | 2010 |
Gene expression patterns in a rodent model for depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Female; Gene Expression; Male; O | 2010 |
Effects of antidepressants on the performance in the forced swim test of two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Clomipramine; Depression; Desi | 2010 |
A novel, multiple symptom model of obsessive-compulsive-like behaviors in animals.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Corpus | 2010 |
Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Clomipramine; Disease Models, Animal; Dose-Response R | 2010 |
Association of clomipramine and allopurinol for the treatment of the experimental infection with Trypanosoma cruzi.
Topics: Allopurinol; Animals; Antibodies, Protozoan; Antigens, Protozoan; Antiprotozoal Agents; Chagas Disea | 2010 |
Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Second | 2011 |
Evaluation of the anxiolytic-like effects of clomipramine in two rat strains with different anxiety vulnerability (Wistar and Wistar-Kyoto rats): participation of 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clo | 2011 |
Predictive validity of a non-induced mouse model of compulsive-like behavior.
Topics: Animals; Anxiety; Behavior, Animal; Clomipramine; Compulsive Behavior; Desipramine; Disease Models, | 2011 |
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experime | 2011 |
Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407-induced hyperlipidaemic model rats.
Topics: Animals; Antidepressive Agents; Blood-Brain Barrier; Brain; Clomipramine; Disease Models, Animal; Ev | 2011 |
Clomipramine, but not haloperidol or aripiprazole, inhibits quinpirole-induced water contrafreeloading, a putative animal model of compulsive behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Clomipramine; Compuls | 2011 |
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic beta-Antagonists; Adrenergi | 2011 |
Sleep-related epilepsy in a Long-Evans hooded rat model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dise | 2012 |
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde; | 2011 |
5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Depression; Disease Models, Animal; | 2012 |
Sleep homeostasis and depression: studies with the rat clomipramine model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depress | 2012 |
Inter-tissue networks between the basal forebrain, hippocampus, and prefrontal cortex in a model for depression caused by disturbed sleep.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Disease Model | 2012 |
Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Clomipramine; Conditioning, Operan | 2012 |
Neonatal tricyclic antidepressant clomipramine treatment reduces the spike-wave discharge activity of the adult WAG/Rij rat.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Choice | 2012 |
Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Body | 2012 |
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease | 2014 |
Ritualistic chewing behavior induced by mCPP in the rat is an animal model of obsessive compulsive disorder.
Topics: Animals; Behavior, Animal; Clomipramine; Diazepam; Disease Models, Animal; Dopamine Antagonists; Flu | 2013 |
Evaluation of animal models of obsessive-compulsive disorder: correlation with phasic dopamine neuron activity.
Topics: Action Potentials; Animals; Animals, Newborn; Clomipramine; Compulsive Behavior; Conditioning, Opera | 2013 |
The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Disease Models, Animal | 2002 |
Sleep-wake effects of yohimbine and atropine in rats with a clomipramine-based model of depression.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Aggression; Animals; Animals, Newborn; Antidepressive Agen | 2002 |
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain Chemistry; Cell Division; Chronic Dise | 2002 |
Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral 'despair' in a mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Dise | 2002 |
Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
Topics: Animals; Arousal; Carrier Proteins; Cells, Cultured; Clomipramine; Disease Models, Animal; Efferent | 2003 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Dise | 2003 |
Corticosterone and testosterone levels after chronic stress in an animal model of depression.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; | 2003 |
Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Blotting, Western; Brain; Clomipramine; | 2003 |
[Effect of concurrent treatment of SSRI on the tyrosine hydroxylase immunoreactivity in the rat locus coeruleus treated with chronic variable stress].
Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Clomipramine; Corticotropin-Releasing Ho | 2004 |
Antidepressants blunt the effects of inescapable stress on male mating behaviour and decrease corticotropin-releasing hormone mRNA expression in the hypothalamic paraventricular nucleus of the Syrian hamster (Mesocricetus auratus).
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clomipramine; Corticotropin-Releasing | 2004 |
Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cell Differentiation; Clomipramine | 2004 |
Stressors affect the response of male and female rats to clomipramine in a model of behavioral despair (forced swim test).
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Corticosterone; Depressio | 2005 |
Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Cell Count; Clomipramine; Desipramine; Disease | 2006 |
Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Dep | 2007 |
Sucrose preference is restored by electro-acupuncture combined with chlorimipramine in the depression-model rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Combined Modality Therapy; Depressio | 2006 |
Behavioral effects of the beta3 adrenoceptor agonist SR58611A: is it the putative prototype of a new class of antidepressant/anxiolytic drugs?
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Antagon | 2007 |
Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus.
Topics: Animals; Antidepressive Agents; Chronic Disease; Clomipramine; Depressive Disorder; Disease Models, | 2008 |
Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Behavior, An | 2008 |
Electrophysiological activity of raphe dorsalis serotoninergic neurones in a possible model of endogenous depression.
Topics: Animals; Antidepressive Agents; Citalopram; Clomipramine; Disease Models, Animal; Male; Membrane Pot | 1995 |
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder.
Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinkin | 1993 |
The effects of a 3-day increase of ambient temperature on body temperature and REM sleep in an animal model of depression.
Topics: Acclimatization; Animals; Animals, Newborn; Body Temperature Regulation; Circadian Rhythm; Clomipram | 1994 |
Decreased raphe unit activity in a rat model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Electric Stimulation; Evoked Pot | 1993 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disea | 1995 |
Clomipramine modifies fluctuations of forced swimming immobility in different phases of the rat estrous cycle.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Disease Models, Animal; Estrus; Female; Mot | 1996 |
Fluoride and pilocarpine reduce the risk of caries produced by chronic clomipramine treatment in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Cariostatic Agents; Cholinergic Antagonists; Cl | 1997 |
Pharmacological features of masculine sexual behavior in an animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clo | 1998 |
Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD).
Topics: Animals; Clomipramine; Disease Models, Animal; Dopamine Agonists; Male; Obsessive-Compulsive Disorde | 1998 |
Hyperactivity of hypothalamic pituitary axis in neonatal clomipramine model of depression.
Topics: Animals; Animals, Newborn; Clomipramine; Depression; Depression, Chemical; Dexamethasone; Disease Mo | 1998 |
Alterations in the levels of monoamines in discrete brain regions of clomipramine-induced animal model of endogenous depression.
Topics: Aggression; Animals; Biogenic Monoamines; Brain; Brain Stem; Clomipramine; Depression; Disease Model | 1999 |
Effects of neonatal clomipramine treatment on locomotor activity, anxiety-related behavior and serotonin turnover in Syrian hamsters.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Brain Chemis | 1999 |
Potentiation of morphine and clomipramine analgesia by cholecystokinin -B antagonist CI-988 in diabetic rats.
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomi | 2000 |
Effects of acute or chronic administration of substituted benzamides in experimental models of depression in rats.
Topics: Animals; Antidepressive Agents; Benzamides; Clomipramine; Depression; Disease Models, Animal; Dose-R | 2000 |
Placebo affects the performance of rats in models of depression: is it a good control for behavioral experiments?
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Model | 2001 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Model | 2001 |
Altered dendritic spine density in animal models of depression and in response to antidepressant treatment.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Dendrites; Denervation; D | 2001 |
Clomipramine suppresses postnatal REM sleep without increasing wakefulness: implications for the production of depressive behaviors.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depress | 2002 |
Neonatal treatment with clomipramine increased immobility in the forced swim test: an attribute of animal models of depression.
Topics: Animals; Animals, Newborn; Clomipramine; Defecation; Depressive Disorder; Disease Models, Animal; Ma | 1992 |
Compulsive feather picking in birds.
Topics: Animals; Animals, Domestic; Bird Diseases; Clomipramine; Disease Models, Animal; Female; Humans; Mal | 1991 |
Procedure- and age-dependent hyperactivity in a new animal model of endogenous depression.
Topics: Aging; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Disease Models, Animal; Hy | 1990 |
Diminished sexual activity in a new animal model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Rats; Rats, Inbred Strains; Sexu | 1990 |
REM sleep abnormalities in a new animal model of endogenous depression.
Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Male; Rats; Rats, Inbred Strains | 1990 |
Treatment of behavioral disorders in animals.
Topics: Animal Diseases; Animals; Animals, Domestic; Clomipramine; Desipramine; Disease Models, Animal; Dog | 1990 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Cl | 1987 |
Animal depression model by neonatal clomipramine: reduction of shock induced aggression.
Topics: Age Factors; Aggression; Animals; Animals, Newborn; Clomipramine; Depression; Disease Models, Animal | 1988 |