Page last updated: 2024-10-25

clomipramine and Depression, Involutional

clomipramine has been researched along with Depression, Involutional in 54 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"Mefloquine (Lariam) is the drug of choice as malaria prophylaxis for travel to chloroquine-resistant areas."7.77[Mood disorder after malaria prophylaxis with mefloquine (two case reports)]. ( Abilkacem, L; Laffinti, A; Oueriagli Nabih, F; Touhami, M, 2011)
"Mefloquine (Lariam) is the drug of choice as malaria prophylaxis for travel to chloroquine-resistant areas."3.77[Mood disorder after malaria prophylaxis with mefloquine (two case reports)]. ( Abilkacem, L; Laffinti, A; Oueriagli Nabih, F; Touhami, M, 2011)
"Aripiprazole was added at the fixed dose of 5mg/day and clinical status as well as clomipramine plasma levels were monitored before and after 4, 8, and 24 weeks of combined treatment."2.77Aripiprazole augmentation strategy in clomipramine-resistant depressive patients: an open preliminary study. ( Catapano, F; Esposito, G; Fabrazzo, M; Maj, M; Monteleone, P; Perris, F, 2012)
"From a clinical point of view, orthostatic hypotension is a significant side effect during antidepressant treatment, particularly in the case of tricyclic antidepressants (TCAs)."2.71Orthostatic side effects of clomipramine and moclobemide during treatment for depression. ( Stage, KB, 2005)
"Major depressive disorder is one of the most common mental disorders in children and adolescents."2.53Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis. ( Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X, 2016)
" Pharmacokinetic and pharmacogenetic analyses may improve drug therapy."1.46The combination of pharmacogenetic and pharmacokinetic analyses to optimize clomipramine dosing in major depression: a case report. ( Altamura, CA; Antoniazzi, S; Bernardi, FF; Cattaneo, D; Cheli, S; Cigliobianco, M; Clementi, E; Falvella, FS; Paoli, RA; Tatulli, A, 2017)
"Treatment with clomipramine alone allowed five patients to achieve sustained remission (MADRS < or = 8), while three patients were responders (MADRS decrease > or = 50%) and three patients were partial responders (MADRS decrease > 25%)."1.35Is there a place for tricyclic antidepressants and subsequent augmentation strategies in obtaining remission for patients with treatment resistant depression? ( Aubry, JM; Bertschy, G; Bondolfi, G; Gervasoni, N; Gex-Fabry, M, 2009)
"Clomipramine was increased to 60 mg/day, and her symptoms subsided."1.35Symptoms of delusion: the effects of discontinuation of low-dose venlafaxine. ( Kodaka, F; Koga, M; Miyata, H; Nakayama, K, 2009)
"Psychiatrists treated major depressive disorder in advanced cancer patients on the basis of the algorithm."1.35Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer. ( Akechi, T; Akizuki, N; Ito, T; Nakano, T; Okamura, M; Shimizu, K; Uchitomi, Y, 2008)
" TDM and pharmacogenetic tests are useful tools to improve pharmacotherapy by preventing dose-dependent adverse drug events, optimizing dosage during long-term treatment and identifying ultrarapid metabolizers and malcompliance."1.33[Therapeutic drug monitoring: A pharmacotherapeutic tool in psychiatry]. ( Etzensberger, M; Jaquenoud Sirot, E; Stephan, PL, 2006)
"Drug treatment with clomipramine and, to a lesser extent, with selective serotonin reuptake inhibitors was associated with hypomanic switches in OCD-bipolar patients, especially in those not concomitantly treated with mood stabilizers."1.31Obsessive-compulsive-bipolar comorbidity: a systematic exploration of clinical features and treatment outcome. ( Akiskal, HS; Frare, F; Hantouche, E; Perugi, G; Toni, C; Travierso, MC, 2002)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.70)18.7374
1990's3 (5.56)18.2507
2000's33 (61.11)29.6817
2010's15 (27.78)24.3611
2020's1 (1.85)2.80

Authors

AuthorsStudies
Joas, E1
Jonsson, L1
Viktorin, A1
Smedler, E1
Pålsson, E1
Goodwin, GM1
Landén, M1
Molina-Jímenez, T1
Landa-Cadena, L1
Bonilla-Jaime, H1
Buoli, M2
Rovera, C1
Pozzoli, SM1
Fiorentini, A1
Cremaschi, L1
Caldiroli, A1
Altamura, AC2
Fortinguerra, S1
Buriani, A1
Sorrenti, V1
Lenzi, M1
Giusti, P1
Berm, EJJ1
Paardekooper, J1
Brummel-Mulder, E1
Hak, E1
Wilffert, B1
Maring, JG1
Arco, L1
Cipriani, A1
Zhou, X1
Del Giovane, C1
Hetrick, SE1
Qin, B1
Whittington, C1
Coghill, D1
Zhang, Y1
Hazell, P1
Leucht, S1
Cuijpers, P1
Pu, J1
Cohen, D1
Ravindran, AV1
Liu, Y1
Michael, KD1
Yang, L1
Liu, L1
Xie, P1
Antoniazzi, S1
Tatulli, A1
Falvella, FS1
Cigliobianco, M1
Paoli, RA1
Cattaneo, D1
Cheli, S1
Bernardi, FF1
Clementi, E1
Altamura, CA1
Dell'Osso, B1
Zanoni, S1
Mundo, E1
Rucker, J1
Cook, M1
Cupello, A1
Bandini, F1
Albano, C1
Favale, E1
Marchese, R1
Scarrone, S1
Trompetto, C1
Kundermann, B2
Strate, P2
Hemmeter-Spernal, J2
Huber, MT2
Krieg, JC2
Lautenbacher, S2
Gervasoni, N1
Aubry, JM1
Gex-Fabry, M1
Bertschy, G1
Bondolfi, G1
Cordes, J1
Larisch, R2
Henning, U2
Thünker, J1
Werner, C1
Orozco, G1
Mayoral, F1
Rivas, F1
Auburger, G1
Tosch, M2
Rietschel, M1
Gaebel, W2
Müller, HW1
Klimke, A2
Carroll, BJ1
Gebhardt, S1
Koga, M1
Kodaka, F1
Miyata, H1
Nakayama, K1
Pitychoutis, PM1
Griva, E1
Ioannou, K1
Tsitsilonis, OE1
Papadopoulou-Daifoti, Z1
Quilty, LC1
Godfrey, KM1
Kennedy, SH1
Bagby, RM1
Mihara, K1
Nakamura, A1
Kuba, T1
Yakushi, T1
Hotta, H1
Kojima, M1
Kondo, T1
Minelli, A1
Bortolomasi, M1
Scassellati, C1
Salvoro, B1
Avesani, M1
Manganotti, P1
Fabrazzo, M1
Perris, F1
Monteleone, P1
Esposito, G1
Catapano, F1
Maj, M1
Oueriagli Nabih, F1
Touhami, M1
Laffinti, A1
Abilkacem, L1
Bech, P1
Stage, KB3
Larsen, JK1
Vestergaard, P1
Gram, LF1
Komorowski, M1
Huston, JP1
Klingenhegel, I1
Paulat, J1
Sackers, J1
Topic, B1
Kovács, Z1
Czurkó, A1
Kékesi, KA1
Juhász, G1
Markianos, M2
Hatzimanolis, J2
Lykouras, L2
Januel, D1
Massot, O1
Poirier, MF1
Olié, JP1
Fillion, G1
van der Hart, MG1
Czéh, B1
de Biurrun, G1
Michaelis, T1
Watanabe, T1
Natt, O1
Frahm, J1
Fuchs, E1
Porter, RJ1
Mulder, RT1
Joyce, PR1
Perugi, G1
Toni, C1
Frare, F1
Travierso, MC1
Hantouche, E1
Akiskal, HS1
Hamacher, K1
Estalji, S1
Hohlfeld, T1
Vosberg, H1
Coenen, HH1
Müller-Gärtner, HW1
Yamada, K1
Yagi, G1
Kanba, S1
Fountoulakis, KN1
Iacovides, A1
St Kaprinis, G1
Chistyakov, AV1
Kaplan, B1
Rubichek, O1
Kreinin, I1
Koren, D1
Feinsod, M1
Klein, E1
Holmes, DT1
Long, P1
Frohlich, J1
Loughhead, AM1
Stowe, ZN1
Newport, DJ1
Ritchie, JC1
DeVane, CL1
Owens, MJ1
Stephan, PL2
Etzensberger, M1
Jaquenoud Sirot, E2
Mueller, B1
Eap, CB1
Baumann, P1
Łojko, D1
Rybakowski, JK1
Okamura, M1
Akizuki, N1
Nakano, T1
Shimizu, K1
Ito, T1
Akechi, T1
Uchitomi, Y1
Marchesi, C1
Tonna, M1
Maggini, C1
Carvalho, LA1
Juruena, MF1
Papadopoulos, AS1
Poon, L1
Kerwin, R1
Cleare, AJ1
Pariante, CM1
Pérez, V1
Bel, N1
Celada, P1
Ortiz, J1
Alvarez, E1
Artigas, F1
Ogura, A1
Morinobu, S1
Kawakatsu, S1
Totsuka, S1
Komatani, A1
Montgomery, SA1
Judge, R1
Golden, RN1
Heine, AD1
Ekstrom, RD1
Bebchuk, JM1
Leatherman, ME1
Garbutt, JC1
Burnand, Y1
Andreoli, A1
Kolatte, E1
Venturini, A1
Rosset, N1
Kragh-Sørensen, PB1
Strian, F1
Albert, W1
Klicpera, C1
Singer, L1
Finance, MF1
Ruh, MD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) a Multicentre Open-label Randomized Controlled Trial Protocol[NCT05814640]Phase 1/Phase 2520 participants (Anticipated)Interventional2023-02-20Recruiting
Development and Evaluation of an Ecological Momentary Assessment (EMA) Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms[NCT04830527]60 participants (Actual)Interventional2020-11-24Terminated (stopped due to The study was terminated early due to the difficulty in recruiting cases during a pandemic period.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for clomipramine and Depression, Involutional

ArticleYear
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Co

2016
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Co

2016
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Co

2016
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Co

2016

Trials

17 trials available for clomipramine and Depression, Involutional

ArticleYear
Is trazodone more effective than clomipramine in major depressed outpatients? A single-blind study with intravenous and oral administration.
    CNS spectrums, 2019, Volume: 24, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antidepressive Agents; Clomipramine;

2019
Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients: a short-term, low dose, randomized, placebo-controlled study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:4

    Topics: Administration, Oral; Antidepressive Agents; Citalopram; Clomipramine; Depressive Disorder, Major; D

2008
Mid-term effects of serial sleep deprivation therapy implemented in cognitive-behavioral treatment on the neuroendocrine response to clomipramine in patients with major depression.
    Journal of psychiatric research, 2009, Volume: 43, Issue:7

    Topics: Adult; Affect; Analysis of Variance; Antidepressive Agents, Tricyclic; Behavior Therapy; Clomipramin

2009
Pain sensitivity in major depression and its relationship to central serotoninergic function as reflected by the neuroendocrine response to clomipramine.
    Journal of psychiatric research, 2009, Volume: 43, Issue:16

    Topics: Antidepressive Agents, Tricyclic; Area Under Curve; Chi-Square Distribution; Clomipramine; Depressiv

2009
Harm avoidance as a mediator of treatment response to antidepressant treatment of patients with major depression.
    Psychotherapy and psychosomatics, 2010, Volume: 79, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major; Dose-Response Rel

2010
Aripiprazole augmentation strategy in clomipramine-resistant depressive patients: an open preliminary study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Aripiprazole; Clomipramine; Dep

2012
The predictive validity of atypical neurovegetative depressive symptoms identified by the first principal component in the DUAG trial of moclobemide versus clomipramine.
    Journal of affective disorders, 2012, Volume: 140, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major; Double-Blind Method; Fem

2012
Serotonergic and dopaminergic neuroendocrine responses of male depressive patients before and after a therapeutic ECT course.
    European archives of psychiatry and clinical neuroscience, 2002, Volume: 252, Issue:4

    Topics: Adult; Aged; Clomipramine; Depressive Disorder, Major; Dopamine Antagonists; Electroconvulsive Thera

2002
Relationship between prolactin responses to ECT and dopaminergic and serotonergic responsivity in depressed patients.
    European archives of psychiatry and clinical neuroscience, 2002, Volume: 252, Issue:4

    Topics: Adult; Aged; Clomipramine; Depressive Disorder, Major; Dopamine Antagonists; Electroconvulsive Thera

2002
Interaction of lithium with 5-HT(1B) receptors in depressed unipolar patients treated with clomipramine and lithium versus clomipramine and placebo: preliminary results.
    Psychiatry research, 2002, Aug-30, Volume: 111, Issue:2-3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Antidepressive Agents; Blood Platelets; Clomi

2002
Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression.
    Psychopharmacology, 2003, Volume: 165, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antidepressive Agents, Tricyclic; Biological Availability;

2003
Influence of synaptic serotonin level on [18F]altanserin binding to 5HT2 receptors in man.
    Behavioural brain research, 2003, Feb-17, Volume: 139, Issue:1-2

    Topics: Adult; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Depressive Disorder, Major; Drug Inter

2003
Clinical efficacy of tandospirone augmentation in patients with major depressive disorder: a randomized controlled trial.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Maj

2003
Antidepressant effects of different schedules of repetitive transcranial magnetic stimulation vs. clomipramine in patients with major depression: relationship to changes in cortical excitability.
    The international journal of neuropsychopharmacology, 2005, Volume: 8, Issue:2

    Topics: Aged; Analysis of Variance; Antidepressive Agents; Cerebral Cortex; Clomipramine; Depressive Disorde

2005
Orthostatic side effects of clomipramine and moclobemide during treatment for depression.
    Nordic journal of psychiatry, 2005, Volume: 59, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder, Major; Drug Administration Sc

2005
Clomipramine dose-effect study in patients with depression: clinical end points and pharmacokinetics. Danish University Antidepressant Group (DUAG).
    Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:2

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Denmark; Depressive Disorder, Major; Do

1999
Psychodynamic psychotherapy and clomipramine in the treatment of major depression.
    Psychiatric services (Washington, D.C.), 2002, Volume: 53, Issue:5

    Topics: Adult; Aged; Awareness; Clomipramine; Combined Modality Therapy; Depressive Disorder, Major; Empathy

2002

Other Studies

36 other studies available for clomipramine and Depression, Involutional

ArticleYear
Effect of CYP2C19 polymorphisms on antidepressant prescription patterns and treatment emergent mania in bipolar disorder.
    The pharmacogenomics journal, 2023, Volume: 23, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Cytochrome P-450 CYP2C19; Cyto

2023
Chronic treatment with estradiol restores depressive-like behaviors in female Wistar rats treated neonatally with clomipramine.
    Hormones and behavior, 2017, Volume: 94

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Behavior, Animal; Clomipramine; Depressive Disorde

2017
Molecular network-selected pharmacogenomics in a case of bipolar spectrum disorder.
    Pharmacogenomics, 2017, Volume: 18, Issue:18

    Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipramine; Depressive Disorder, Major; Female

2017
A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS.
    Talanta, 2015, Volume: 134

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Calibration; Chromatography, Liq

2015
A case study in treating chronic comorbid obsessive-compulsive disorder and depression with behavioral activation and pharmacotherapy.
    Psychotherapy (Chicago, Ill.), 2015, Volume: 52, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Behavior Therapy; Chronic Disease; Clomipramine; Depressive Di

2015
The combination of pharmacogenetic and pharmacokinetic analyses to optimize clomipramine dosing in major depression: a case report.
    Journal of clinical pharmacy and therapeutics, 2017, Volume: 42, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major; Drug Monitoring; Female;

2017
A case of prolonged seizure after ECT in a patient treated with clomipramine, lithium, L-tryptophan, quetiapine, and thyroxine for major depression.
    The journal of ECT, 2008, Volume: 24, Issue:4

    Topics: Affect; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Age

2008
Catatonic features in major depression relieved by electroconvulsive treatment: parallel evaluation of the status of platelet serotonin transporter.
    The International journal of neuroscience, 2008, Volume: 118, Issue:10

    Topics: Aged; Blood Platelets; Catatonia; Clomipramine; Depressive Disorder, Major; Dose-Response Relationsh

2008
Is there a place for tricyclic antidepressants and subsequent augmentation strategies in obtaining remission for patients with treatment resistant depression?
    Pharmacological research, 2009, Volume: 59, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major; Drug Resistance;

2009
Abnormal neuroendocrine response to clomipramine in hereditary affective psychosis.
    Depression and anxiety, 2009, Volume: 26, Issue:8

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipramine; Depressive Disorder,

2009
Clomipramine and glucocorticoid receptor function.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major; Dexamethasone; Dose-Resp

2009
Symptoms of delusion: the effects of discontinuation of low-dose venlafaxine.
    Acta psychiatrica Scandinavica, 2009, Volume: 120, Issue:4

    Topics: Adult; Clomipramine; Cyclohexanols; Delusions; Depressive Disorder, Major; Dose-Response Relationshi

2009
Chronic antidepressant treatment exerts sexually dimorphic immunomodulatory effects in an experimental model of major depression: do females lack an advantage?
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:9

    Topics: Animals; Antidepressive Agents, Tricyclic; Cell Proliferation; Cells, Cultured; Chronic Disease; Clo

2009
Ropinirole augmentation therapy in a case with treatment-resistant unipolar depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, May-30, Volume: 34, Issue:4

    Topics: Aged; Antidepressive Agents; Clomipramine; Depressive Disorder, Major; Dopamine Agonists; Drug Thera

2010
Effects of intravenous antidepressant drugs on the excitability of human motor cortex: a study with paired magnetic stimulation on depressed patients.
    Brain stimulation, 2010, Volume: 3, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Depressive Disorder, Major; Evoked Poten

2010
[Mood disorder after malaria prophylaxis with mefloquine (two case reports)].
    L'Encephale, 2011, Volume: 37, Issue:5

    Topics: Adult; Antimalarials; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clomipramine; Depress

2011
Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Clomipramine; Conditioning, Operan

2012
Neonatal tricyclic antidepressant clomipramine treatment reduces the spike-wave discharge activity of the adult WAG/Rij rat.
    Brain research bulletin, 2012, Nov-01, Volume: 89, Issue:3-4

    Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Choice

2012
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume.
    Molecular psychiatry, 2002, Volume: 7, Issue:9

    Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain Chemistry; Cell Division; Chronic Dise

2002
Obsessive-compulsive-bipolar comorbidity: a systematic exploration of clinical features and treatment outcome.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:12

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; C

2002
Combined oral venlafaxine and intravenous clomipramine-A: successful temporary response in a patient with extremely refractory depression.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2004, Volume: 49, Issue:1

    Topics: Administration, Oral; Adult; Clomipramine; Cyclohexanols; Depressive Disorder, Major; Diagnostic and

2004
Dysbetalipoproteinemia and clomipramine.
    The American journal of psychiatry, 2005, Volume: 162, Issue:7

    Topics: Antidepressive Agents, Tricyclic; Apolipoprotein E2; Apolipoproteins E; Clomipramine; Depressive Dis

2005
Placental passage of tricyclic antidepressants.
    Biological psychiatry, 2006, Feb-01, Volume: 59, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Birth Weight; Clomipramine; Depressive Disorder, Major; Dose-Respo

2006
[Therapeutic drug monitoring: A pharmacotherapeutic tool in psychiatry].
    Praxis, 2006, Apr-26, Volume: 95, Issue:17

    Topics: Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bio

2006
Adverse drug reactions following nonresponse in a depressed patient with CYP2D6 deficiency and low CYP 3A4/5 activity.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:4

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cholelithiasis; Clomi

2006
L-thyroxine augmentation of serotonergic antidepressants in female patients with refractory depression.
    Journal of affective disorders, 2007, Volume: 103, Issue:1-3

    Topics: Adult; Bipolar Disorder; Clomipramine; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Co

2007
Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer.
    Psycho-oncology, 2008, Volume: 17, Issue:2

    Topics: Adult; Aged; Algorithms; Alprazolam; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzod

2008
Obsessive-compulsive disorder followed by psychotic episode in long-term ecstasy misuse.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Antipsychotic Agents; B

2009
Clomipramine in vitro reduces glucocorticoid receptor function in healthy subjects but not in patients with major depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:13

    Topics: Adult; Brain; Brain Chemistry; Cells, Cultured; Clomipramine; Depressive Disorder, Major; Dose-Respo

2008
Relationship between blood serotonergic variables, melancholic traits, and response to antidepressant treatments.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:3

    Topics: Adult; Antidepressive Agents; Blood Platelets; Clomipramine; Depressive Disorder; Depressive Disorde

1998
Changes in regional brain activity in major depression after successful treatment with antidepressant drugs.
    Acta psychiatrica Scandinavica, 1998, Volume: 98, Issue:1

    Topics: Adult; Amoxapine; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Depressive

1998
Treatment of depression with associated anxiety: comparisons of tricyclic antidepressants and selective serotonin reuptake inhibitors.
    Acta psychiatrica Scandinavica. Supplementum, 2000, Volume: 403

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Clomipramine; Depressive Disorder, Major; Fluox

2000
A longitudinal study of serotonergic function in depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Clomipramine; Depressive Disorder, Major;

2002
Age-related adverse drug reactions to clomipramine.
    Acta psychiatrica Scandinavica, 2002, Volume: 105, Issue:1

    Topics: Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Major

2002
Antidepressive treatment and mood swing patterns in endogenous depression.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1979, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipra

1979
[Pulmonary embolisms occurring in 1 month in 3 aged women with manic-depressive psychoses. Discussion. Etiopathogenic role or psychiatric treatment].
    Annales medico-psychologiques, 1975, Volume: 1, Issue:2

    Topics: Aged; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clomipramine; Depressive Disorder, Ma

1975