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clomipramine and Depression, Endogenous

clomipramine has been researched along with Depression, Endogenous in 383 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Research Excerpts

ExcerptRelevanceReference
"We examined the effects of long-term (six months) treatment with the serotonin potentiating tricyclic antidepressant clomipramine on several serotonergic parameters in panic disorder and depressive patients."9.08Effects of clomipramine on plasma amino acids and serotonergic parameters in panic disorder and depression. ( Fekkes, D; Pepplinkhuizen, L; Timmerman, L, 1997)
"There have been many attempts to find predictors of the therapeutic response to the clomipramine treatment of obsessive-compulsive disorder."9.07Predictors of treatment response in obsessive-compulsive disorder: multivariate analyses from a multicenter trial of clomipramine. ( Ackerman, DL; Bystritsky, A; Greenland, S; Katz, RJ; Morgenstern, H, 1994)
"A double-blind clinical trial of clomipramine versus phenelzine was carried out on 30 patients suffering from DSM-III obsessive-compulsive disorder."9.07Clomipramine versus phenelzine in obsessive-compulsive disorder. A controlled clinical trial. ( Bulbena, A; Marcos, T; Menchón, JM; Olivares, J; Vallejo, J, 1992)
"Seventeen outpatients with panic anxiety and agoraphobia were treated with a low, flexible dose of clomipramine in an 8-week open trial."9.06Panic attacks and agoraphobia: low dose clomipramine treatment. ( Codner, S; Cohen, L; Gladic, D; Gloger, S; Grunhaus, L; O'Ryan, F, 1989)
"The effect of clomipramine hydrochloride in severe obsessive-compulsive disorder (OCD) was compared with that of nortriptyline hydrochloride and placebo in a five-week randomized, double-blind trial."9.05Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial. ( Asberg, M; Cronholm, B; Jörnestedt, L; Thorén, P; Träskman, L, 1980)
"In this retrospective analysis, we analyzed all clinical record data in our Medical Division between January 2005 and December 2006 to evaluate an association between clomipramine treatment and glucose intolerance."7.80Diabetes mellitus associated with clomipramine treatment: a retrospective analysis. ( Cei, M; Cocciolo, M; Gambaccini, L; Mantellassi, M; Mumoli, N; Sabatini, S; Vitale, J, 2014)
" All of them met the ICD-10 criteria for anorexia nervosa and depressive episode and received an antidepressant medication with clomipramine or paroxetine."7.72[Paroxetine versus clomipramine in female adolescents suffering from anorexia nervosa and depressive episode--a retrospective study on tolerability, reasons for discontinuing the antidepressive treatment and different outcome measurements]. ( Roth, M; Schulze, U; Strobel, M; Warnke, A, 2004)
"We present a puzzling case of a 25-year-old depressive man suffering from seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration."7.70A puzzling case of seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration. ( Ohmori, O; Shinkai, T; Terao, T, 1999)
"An epileptic patient well controlled on valproic acid (VPA) developed a prolonged episode of status epilepticus 12 days after initiation of 75 mg of clomipramine (CMI) to treat depression."7.69Status epilepticus associated with the combination of valproic acid and clomipramine. ( DeToledo, JC; Haddad, H; Ramsay, RE, 1997)
"One schizophrenic and two manic-depressive patients who after the administration of zotepine, a new antipsychotic and antimanic drug, developed alopecia areata, a kind of autoimmune disease, are reported."7.68Three cases of alopecia areata induced by zotepine. ( Ishikura, T; Jibiki, I; Kubota, T, 1993)
"A 67-year-old man developed concurrent severe agranulocytosis and elevation of hepatic transaminases as a result of treatment with clomipramine."7.68Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy. ( Alderman, CP; Atchison, MM; McNeece, JI, 1993)
"The case is described of a neonate who suffered from withdrawal symptoms within 24 hours after birth as a result of the use of clomipramine by the mother during pregnancy."7.68[Neonatal withdrawal symptoms following the use of clomipramine during pregnancy]. ( Boringa, JB; de Jong, GM; Touw, DJ, 1992)
"Two patients suffering from severe obsessive-compulsive disorder which had proven refractory to clomipramine and/or phenelzine treatment were successfully treated with fluoxetine, a new drug with a strong serotonin uptake inhibiting action."7.68Fluoxetine treatment of obsessive-compulsive disorder. ( Ledwidge, B; Solyom, C; Solyom, L, 1991)
"In the present study patients with a major depressive disorder were first subjected to total sleep deprivation (TSD) and then treated with clomipramine."7.68The effects of total sleep deprivation and subsequent treatment with clomipramine on depressive symptoms and sleep electroencephalography in patients with a major depressive disorder. ( Berger, M; Riemann, D, 1990)
"In October of 1989, a clustering of cases with eosinophilia lead to the identification of a new syndrome: The eosinophilia myalgia syndrome associated with the use of an L-tryptophan product."7.68Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan. ( Goronzy, JJ; Weyand, CM, 1990)
"A 54-year old man developed pancytopenia after receiving clomipramine for a major depressive episode with psychotic features."7.67Clomipramine-induced pancytopenia. ( Grassetto, M; Magni, G; Silvestro, A; Urbani, A, 1987)
"Milnacipran is a new antidepressant with similar effects on the reuptake of noradrenaline and serotonin in vivo and in vitro."6.68A double-blind six months comparative study of milnacipran and clomipramine in major depressive disorder. ( Den Boer, JA; Steen, A, 1997)
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."6.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
" Safety was monitored weekly by recording body weight, blood pressure, pulse rate, temperature, physical conditions, laboratory tests, adverse experiences and concomitant medication."6.66Double-blind controlled study on the clinical efficacy and safety of fluoxetine vs clomipramine in the treatment of major depressive disorders. ( Agnoli, A; Manna, V; Martucci, N, 1989)
"Fengabine is a new GABAmimetic compound active in animal models predictive of antidepressant activity."6.66Fengabine, a new GABAmimetic agent in the treatment of depressive disorders: an overview of six double-blind studies versus tricyclics. ( Garreau, M; Magni, G; Orofiamma, B; Palminteri, R, 1989)
"In teeth with ligature, mean alveolar bone loss varied from 0."5.35Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats. ( Gaio, EJ; Rosing, CK; Soletti, AC, 2009)
"Major depressive disorder in adolescents is characterized as treatment resistant, but a previous open-label trial of pulse intravenous clomipramine demonstrated rapid relief of depressive symptoms."5.08Pulse intravenous clomipramine for depressed adolescents: double-blind, controlled trial. ( Carson, SW; Deas-Nesmith, D; Sallee, FR; Sethuraman, G; Vrindavanam, NS, 1997)
"We examined the effects of long-term (six months) treatment with the serotonin potentiating tricyclic antidepressant clomipramine on several serotonergic parameters in panic disorder and depressive patients."5.08Effects of clomipramine on plasma amino acids and serotonergic parameters in panic disorder and depression. ( Fekkes, D; Pepplinkhuizen, L; Timmerman, L, 1997)
"There have been many attempts to find predictors of the therapeutic response to the clomipramine treatment of obsessive-compulsive disorder."5.07Predictors of treatment response in obsessive-compulsive disorder: multivariate analyses from a multicenter trial of clomipramine. ( Ackerman, DL; Bystritsky, A; Greenland, S; Katz, RJ; Morgenstern, H, 1994)
" Three tricyclic antidepressants examined (imipramine, clomipramine and desipramine) did not seem to have the side effect of pathological weight gain in the frequency distribution pattern."5.07Changes in the frequency distribution pattern of body weight in patients with major depression. ( Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N, 1993)
"A double-blind clinical trial of clomipramine versus phenelzine was carried out on 30 patients suffering from DSM-III obsessive-compulsive disorder."5.07Clomipramine versus phenelzine in obsessive-compulsive disorder. A controlled clinical trial. ( Bulbena, A; Marcos, T; Menchón, JM; Olivares, J; Vallejo, J, 1992)
"Prolactin (PRL) and cortisol responses to oral administration of d-1 fenfluramine hydrochloride (60 mg) and placebo were examined in patients with endogenous major depressive disorder on three separate occasions: prior to treatment with clomipramine (CMI), after 4 weeks of CMI administration (175-250) mg/day), and 3 weeks after addition of lithium (Li) carbonate (serum level 0."5.07Effect of clomipramine and lithium on fenfluramine-induced hormone release in major depression. ( Gropp, C; Lerer, B; Newman, M; Shapira, B; Yagmur, MJ, 1992)
"Seventeen outpatients with panic anxiety and agoraphobia were treated with a low, flexible dose of clomipramine in an 8-week open trial."5.06Panic attacks and agoraphobia: low dose clomipramine treatment. ( Codner, S; Cohen, L; Gladic, D; Gloger, S; Grunhaus, L; O'Ryan, F, 1989)
"In a double-blind study on 22 patients with major depressive disorder the effects of lithium and clomipramine on signs and symptoms and on calcium and magnesium in plasma were compared."5.06Acute antidepressant effect of lithium is associated with fluctuation of calcium and magnesium in plasma. A double-blind study on the antidepressant effect of lithium and clomipramine. ( Fyrö, B; Linder, J; Pettersson, U; Werner, S, 1989)
"Most of the controlled studies on the efficacy of medical treatments of obsessive-compulsive disorder (OCD) have involved clomipramine, a tricyclic antidepressant reputed to have anti-obsessional properties."5.06Effects of imipramine on depression and obsessive-compulsive symptoms. ( Dugger, D; Foa, EB; Kozak, MJ; Steketee, G, 1987)
" Thirty-eight patients with episodic, chronic and atypical depressive disorder (DSM-III) were equally randomized to 6 weeks' treatment with either three daily doses of 100 mg moclobemide or 50 mg clomipramine."5.05Moclobemide and clomipramine in the treatment of depression. A randomized clinical trial. ( Holm, P; Larsen, JK; Mikkelsen, PL, 1984)
"The effect of clomipramine hydrochloride in severe obsessive-compulsive disorder (OCD) was compared with that of nortriptyline hydrochloride and placebo in a five-week randomized, double-blind trial."5.05Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial. ( Asberg, M; Cronholm, B; Jörnestedt, L; Thorén, P; Träskman, L, 1980)
" Results of short term clinical trials have shown paroxetine to be significantly superior to placebo, and comparable to amitriptyline, clomipramine, imipramine, dothiepin and mianserin in relieving symptoms associated with major depressive disorders."4.78Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness. ( Clissold, SP; Dechant, KL, 1991)
"In this retrospective analysis, we analyzed all clinical record data in our Medical Division between January 2005 and December 2006 to evaluate an association between clomipramine treatment and glucose intolerance."3.80Diabetes mellitus associated with clomipramine treatment: a retrospective analysis. ( Cei, M; Cocciolo, M; Gambaccini, L; Mantellassi, M; Mumoli, N; Sabatini, S; Vitale, J, 2014)
" During and at the end point of the chronic stress experiment, food consumption, body weight, adrenal gland, thymus and spleen indices, behavior scores, sucrose consumption, and stress hormone levels were measured."3.78Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression. ( Chen, T; Jia, W; Jia, Z; Jiang, T; Lin, J; Qiu, Y; Su, M; Wang, X; Xie, X; Zeng, C; Zhao, A; Zhao, T; Zhou, M, 2012)
" Risk of increasing suicidal ideation was higher in subjects taking antidepressants other than paroxetine (odds ratio: 1."3.77Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample. ( Aubry, JM; Bertschy, G; Bondolfi, G; Gex-Fabry, M; Kosel, M; Malafosse, A; Perroud, N; Uher, R, 2011)
"We describe a 55-year-old woman with extensive digestive resection and recurrent depressive disorder resistant to oral clomipramine tablets but not to an oral solution of amitriptyline."3.77Therapeutic drug monitoring of clomipramine and amitriptyline in a depressed patient with upper digestive tract resection. ( Allilaire, JF; Couturier, PL; Goldwirt, L; Lambrey, S; Warot, D; Zahr, N, 2011)
"Treatment with clomipramine, a tricyclic antidepressant, has proved useful for obsessional patients either as an adjunct to behavior therapy or as a primary treatment for patients who are not amenable to behavioral interventions."3.75Obsessive-compulsive disorder. ( Insel, TR, 1985)
"The authors report an improvement in delusions and hallucinations after antidepressant treatment (Clomipramine) in a parkinsonian patient with psychosis and comorbid depression."3.74Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease. ( Bernardi, S; Meco, G, 2007)
" All of them met the ICD-10 criteria for anorexia nervosa and depressive episode and received an antidepressant medication with clomipramine or paroxetine."3.72[Paroxetine versus clomipramine in female adolescents suffering from anorexia nervosa and depressive episode--a retrospective study on tolerability, reasons for discontinuing the antidepressive treatment and different outcome measurements]. ( Roth, M; Schulze, U; Strobel, M; Warnke, A, 2004)
"We present a puzzling case of a 25-year-old depressive man suffering from seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration."3.70A puzzling case of seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration. ( Ohmori, O; Shinkai, T; Terao, T, 1999)
"The aim of this paper is to describe two cases of clomipramine-induced delirium."3.70Delirious episodes induced by intravenous administration of clomipramine associated with an acute increase in its plasma concentrations. ( Eto, S; Nakamura, J; Terao, T; Ueda, N; Yoshimura, R, 2000)
"An epileptic patient well controlled on valproic acid (VPA) developed a prolonged episode of status epilepticus 12 days after initiation of 75 mg of clomipramine (CMI) to treat depression."3.69Status epilepticus associated with the combination of valproic acid and clomipramine. ( DeToledo, JC; Haddad, H; Ramsay, RE, 1997)
"One schizophrenic and two manic-depressive patients who after the administration of zotepine, a new antipsychotic and antimanic drug, developed alopecia areata, a kind of autoimmune disease, are reported."3.68Three cases of alopecia areata induced by zotepine. ( Ishikura, T; Jibiki, I; Kubota, T, 1993)
"A 67-year-old man developed concurrent severe agranulocytosis and elevation of hepatic transaminases as a result of treatment with clomipramine."3.68Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy. ( Alderman, CP; Atchison, MM; McNeece, JI, 1993)
"The case is described of a neonate who suffered from withdrawal symptoms within 24 hours after birth as a result of the use of clomipramine by the mother during pregnancy."3.68[Neonatal withdrawal symptoms following the use of clomipramine during pregnancy]. ( Boringa, JB; de Jong, GM; Touw, DJ, 1992)
"Performance on tasks tapping automatic and voluntary aspects of memory, attention, and motor speed was examined in 14 patients with major depressive disorder, before and after 3 weeks of treatment with clomipramine (150 mg/day), a potent serotonin and noradrenaline uptake blocker with anticholinergic side effects."3.68Memory effects of clomipramine treatment: relationship to CSF monoamine metabolites and drug concentrations in plasma. ( Asberg, M; Bartfai, A; Gustavsson, P; Mårtensson, B, 1991)
"Painful ejaculation following the administration of imipramine and clomipramine is described in four patients."3.68Painful ejaculation associated with antidepressants in four patients. ( Aizenberg, D; Hermesh, H; Karp, L; Weizman, A; Zemishlany, Z, 1991)
"Two patients suffering from severe obsessive-compulsive disorder which had proven refractory to clomipramine and/or phenelzine treatment were successfully treated with fluoxetine, a new drug with a strong serotonin uptake inhibiting action."3.68Fluoxetine treatment of obsessive-compulsive disorder. ( Ledwidge, B; Solyom, C; Solyom, L, 1991)
"In the present study patients with a major depressive disorder were first subjected to total sleep deprivation (TSD) and then treated with clomipramine."3.68The effects of total sleep deprivation and subsequent treatment with clomipramine on depressive symptoms and sleep electroencephalography in patients with a major depressive disorder. ( Berger, M; Riemann, D, 1990)
"In October of 1989, a clustering of cases with eosinophilia lead to the identification of a new syndrome: The eosinophilia myalgia syndrome associated with the use of an L-tryptophan product."3.68Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan. ( Goronzy, JJ; Weyand, CM, 1990)
"Antidepressant therapy for panic attacks, exposure therapy for stimulus-dependent anxieties, and, to a lesser extent, clomipramine therapy for obsessive-compulsive symptoms have transformed the treatment of anxiety disorders and ushered in an era of rapid progress in research on anxiety and anxiety disorders."3.67New findings in anxiety. A synthesis for clinical practice in 1985. ( Curtis, GC, 1985)
"A 54-year old man developed pancytopenia after receiving clomipramine for a major depressive episode with psychotic features."3.67Clomipramine-induced pancytopenia. ( Grassetto, M; Magni, G; Silvestro, A; Urbani, A, 1987)
" Sixty-three depressed women (major depressive disorder) and 21 paranoid-hallucinatory women have been studied while on antidepressant (clomipramine) or neuroleptic (haloperidol) treatment, respectively."3.66The TSH-response to TRH: A possible predictor of outcome to antidepressant and neuroleptic treatment. ( Aschauer, H; Koinig, G; Langer, G; Resch, F; Schönbeck, G, 1983)
"ECGs and left ventricular systolic time intervals were studied in 26 patients suffering from major depressive disorder treated with clomipramine."3.66Cardiac effects of clomipramine treatment. ECG and left ventricular systolic time intervals. ( Brat, A; Faravelli, C; Franchi, F; Marchetti, G; Michelucci, A; Padeletti, L; Pastorino, A, 1983)
"Children and young adolescents with either depressive syndromes or enuresis were treated with clomipramine for periods of 1 to 9 months."3.66[Plasma level monitoring of psychotropic drugs in children. II -- Antidepressants (author's transl)]. ( Dugas, M; Durand, G; Le Heuzey, MF; Morselli, PL; Regnier, N; Rovei, V; Zarifian, E, 1982)
"Clomipramine was associated with a higher incidence of overall and treatment-related adverse events."2.71Fluvoxamine as effective as clomipramine against symptoms of severe depression: results from a multicentre, double-blind study. ( Barrelet, L; Keegstra, H; Zohar, J, 2003)
"Clomipramine (150 mg/day) was the reference treatment, and comparable treatments were citalopram (40 mg/day), paroxetine (30 mg/day), and moclobemide (400 mg/day)."2.71Are gender differences important for the clinical effects of antidepressants? ( Hildebrandt, MG; Kragh-Soerensen, P; Passchier, J; Stage, KB; Steyerberg, EW, 2003)
" There were more withdrawals due to adverse events in the clomipramine group than in the sertraline group (17% versus 12%)."2.69A double-blind study of the efficacy and safety of sertraline and clomipramine in outpatients with severe major depression. ( Blashko, C; Goger, J; Kosolowski, J; Lane, RM; Lépine, JP; Moles, MF; Probst, C; Scharfetter, B, 2000)
"Tachycardia was the most common change (36%)."2.68Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents. ( Allen, AJ; Hamburger, SD; Leonard, HL; Meyer, MC; Rapoport, JL; Richter, D; Swedo, SE; Tucker, E, 1995)
" EEG, ECG, and laboratory parameters and adverse effects reported by the patients, as well as global clinical improvement, were assessed."2.68Combination treatment with clomipramine and fluvoxamine: drug monitoring, safety, and tolerability data. ( Härtter, S; Hiemke, C; Leal, M; Szegedi, A; Wetzel, H, 1996)
"Clomipramine proved to be a useful treatment of depression in patients with probable AD."2.68A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. ( Chemerinski, E; Leiguarda, R; Petracca, G; Starkstein, SE; Tesón, A, 1996)
"Milnacipran is a new antidepressive drug, a combined noradrenaline/serotonin (NA/5-HT) reuptake inhibitor, which has been suggested to be as effective as and better tolerated than tricyclic antidepressants."2.68Long-term efficacy and safety of milnacipran compared to clomipramine in patients with major depression. ( Koponen, H; Leinonen, E; Lepola, U; Mehtonen, OP; Rimon, R, 1997)
"Milnacipran is a new antidepressant with similar effects on the reuptake of noradrenaline and serotonin in vivo and in vitro."2.68A double-blind six months comparative study of milnacipran and clomipramine in major depressive disorder. ( Den Boer, JA; Steen, A, 1997)
"Two different initial dosing regimens with clomipramine (CMI) were used to compare early response indicators and dose strategies."2.67Effect of pulse loading with clomipramine on EEG sleep. ( Ehlers, CL; Grochocinski, VJ; Kupfer, DJ; Miewald, JM; Perel, JM; Pollock, BG, 1994)
"Desmethylclomipramine levels were significantly greater in P-L nonresponders (p = 0."2.67Early response patterns associated with successful clomipramine treatment. ( Bowler, KA; Kupfer, DJ; Miewald, JM; Perel, JM; Pollock, BG, 1993)
"The pharmacokinetic parameters and the time course of the effect after acute oral administration of yohimbine on salivary secretion in patients treated with tricyclic antidepressants were investigated."2.67Pharmacokinetic study of yohimbine and its pharmacodynamic effects on salivary secretion in patients treated with tricyclic antidepressants. ( Bagheri, H; Berlan, M; Houin, G; Montastruc, JL; Picault, P; Schmitt, L, 1994)
"In 14 cases tremor and myoclonus occurred simultaneously, and 10 patients presented at the same time tremor plus myoclonus, diaphoresis and shivering."2.67Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine. ( Adès, J; Lejoyeux, M; Rouillon, F, 1993)
"Moclobemide was compared with isocarboxazide and clomipramine in patients with depression."2.67Moclobemide in depression: a randomized, multicentre trial against isocarboxazide and clomipramine emphasizing atypical depression. ( Anderson, J; Bille, A; Christensen, EM; Gjerris, A; Holm, P; Høyer, E; Jensen, H; Langagergaard, A; Larsen, JK; Mejlhede, A, 1991)
" The frequency of adverse events in response to fluoxetine was lower than under clomipramine treatment."2.67[Efficacy and safety of fluoxetine versus clomipramine in ambulatory patients with a depressive syndrome in a clinical trial with private practitioners]. ( Dossenbach, M; Pakesch, G, 1991)
"Improvement in depression after total sleep deprivation (TSD) is, as a rule, followed by relapse after subsequent ad libitum sleep."2.67Total and partial sleep deprivation in clomipramine-treated endogenous depressives. ( Beersma, D; Elsenga, S; Van den Hoofdakker, RH, 1990)
"Moclobemide was compared with clomipramine for safety and efficacy in 2 groups of 15 patients each with endogenous depression."2.67Moclobemide versus clomipramine in the treatment of depression: a single-centre study, Federal Republic of Germany. ( Funke, HJ; Hellstern, K; Malanowski, H; Moritz, E, 1990)
"Patients with endogenous depression responded better to clomipramine, whereas nonendogenous disorders did better on moclobemide."2.67Moclobemide versus clomipramine in the treatment of depression: a double-blind multicentre study in Belgium. ( Berger, M; Burton, P; Cattiez, P; Defleur, J; Dierick, M; Franck, G; Hellstern, K; Hermans, W; Roelandts, A; Wolfrum, C, 1990)
" Although the bioavailability of parenteral clomipramine was greater, there were no significant differences in either efficacy or side effects between the two groups."2.66Acute antidepressant effect following pulse loading with intravenous and oral clomipramine. ( Kupfer, DJ; Nathan, RS; Perel, JM; Pollock, BG, 1989)
" Safety was monitored weekly by recording body weight, blood pressure, pulse rate, temperature, physical conditions, laboratory tests, adverse experiences and concomitant medication."2.66Double-blind controlled study on the clinical efficacy and safety of fluoxetine vs clomipramine in the treatment of major depressive disorders. ( Agnoli, A; Manna, V; Martucci, N, 1989)
"Fengabine is a new GABAmimetic compound active in animal models predictive of antidepressant activity."2.66Fengabine, a new GABAmimetic agent in the treatment of depressive disorders: an overview of six double-blind studies versus tricyclics. ( Garreau, M; Magni, G; Orofiamma, B; Palminteri, R, 1989)
" The study was conducted over a period of 28 days and the dosage of each substance, after being gradually increased, was stabilized at 150 mg."2.66CGP 12.103 A versus clomipramine in the treatment of depressed inpatients--results of a double-blind study. ( Binz, U; Hole, G; Steiner, B; Wendt, G; Wolfersdorf, M, 1988)
"In a double-blind study on 38 unselected depressive inpatients (19 per group) suffering from endogenous and psychogenic depression, oxaprotiline, a new tetracyclic compound, a hydroxylized maprotiline with a highly selective norepinephrine reuptake inhibition, was compared with clomipramine over a period of 28 days in a daily dosage of 150 mg."2.66Double-blind study of oxaprotiline versus clomipramine in the treatment of depressive inpatients. ( Binz, U; Hole, G; Metzger, R; Wendt, G; Wolfersdorf, M, 1987)
"A negative response to sleep deprivation, an increase in MAO activity as a result of sleep deprivation, the appearance of signs of fatigue (vigilance index) in the EEG after the first infusion as well as obvious autonomic symptoms before the start of treatment are indicative of a response to maprotiline."2.66Biological predictors of success of antidepressant drug therapy. ( Fähndrich, E, 1987)
"Orthostatic hypotension, the clinically most important side effect in treatment with tricyclic antidepressants, was investigated in a double-blind study with clomipramine and the selective serotonin reuptake inhibitor citalopram given for 5 weeks."2.66Orthostatic side effects of clomipramine and citalopram during treatment for depression. ( Christensen, P; Gram, LF; Kragh-Sørensen, P; Pedersen, OL; Thomsen, HY, 1985)
"Amineptine was however much better tolerated than clomipramine."2.66Amineptine in the management of the depressive syndromes. ( Bergamasco, B; Mailland, F; Scarzella, L; Scarzella, R, 1985)
"Fluvoxamine was superior to chlorimipramine in all the rating scales used without achieving statistical significance."2.65Fluvoxamine and chlorimipramine in endogenous depression. ( De Wilde, JE; Doogan, DP, 1982)
"Clomipramine was effective, safe, and well tolerated as compared to doxepin in the treatment of outpatients with neurotic depression."2.65A comparison of clomipramine and doxepin in neurotic depression. ( Horwitz, IM; Kornhaber, A, 1984)
" Patients in each group received chlorimipramine (50 mg/day), combined with L-5-HTP (300 mg/day) in Group A, and with placebo in Group B."2.65Treatment of depression with L-5-hydroxytryptophan combined with chlorimipramine, a double-blind study. ( Battistini, N; Borghesi, R; De Stefano, R; Iannuccelli, M; Nardini, M, 1983)
" Thirty-two patients with mixed depression received one or the other drug at the same daily dosage of 150 mg."2.65A double-blind comparative study of the clinical efficacy of fluvoxamine and chlorimipramine. ( Dick, P; Ferrero, E, 1983)
" In the first study the effects of a single daily dosage of between 100 and 300 mg of fluvoxamine were compared with those of chlorimipramine at a dosage of 50-150 mg daily in 43 out-patients with endogenous depression."2.65Clinical trials of fluvoxamine vs chlorimipramine with single and three times daily dosing. ( De Wilde, JE; Mertens, C; Wakelin, JS, 1983)
"1."2.65Fluvoxamine maleate, a serotonergic antidepressant; a comparison with chlorimipramine. ( Block, BA; Coleman, BS, 1982)
"Mianserin (60 mg daily) was compared with chlorimipramine (150 mg daily) in the treatment of 145 depressed in- and outpatients in four centres."2.65A double-blind multicentre trial comparing the efficacy and side-effects of mianserin and chlorimipramine in depressed in- and outpatients. ( Barres, M; Blum, A; Charbaut, J; Israel, L; Kammerer, T; Molczadzki, M; Pinder, RM; Rigaud, A; Stulemeijer, SM, 1980)
"In a previous study it was shown that in endogenous depression repeated sleep deprivation (SD) during clomipramine treatment resulted in rapid improvement after each SD."2.65Maintenance of therapeutic effects of total sleep deprivation by limitation of subsequent sleep. A pilot study. ( van Bemmel, AL; van den Hoofdakker, RH, 1981)
" In contrast, in 7 other patients receiving a dosage increasing to 150 mg per day at Day 7, mean plasma levels of C1 and DMC1 continued to rise during the entire treatment period."2.65Relationship between the plasma concentration of clomipramine and desmethylclomipramine in depressive patients and the clinical response. ( Allers, G; Jounet, JM; Vandel, B; Vandel, S; Volmat, R, 1982)
"Mirtazapine is a noradrenergic and specific serotonergic antidepressant, characterized by a unique pharmacologic profile, favorable pharmacokinetics, and proven efficacy and safety."2.40Mirtazapine: clinical advantages in the treatment of depression. ( Burrows, GD; Kremer, CM, 1997)
" In many instances, a knowledge of the drug metabolism status of a patient can be helpful in the selection of a drug and its dosage regimen, and in the prediction of possible drug/drug interactions when two or more drugs have to be administered concomitantly."2.39Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping. ( Coutts, RT, 1994)
"Depression has recently been referred to as a neuroimmune disease because it is characterized by inflammatory changes in the cerebral cortex and hippocampus."1.51Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine. ( Gong, W; Halim, M; Li, B; Liu, Q; Ma, L; Ma, Y; Ren, Z; Wang, Y; Yu, J; Zhang, J; Zhang, S; Zhou, G; Zong, Y, 2019)
"Depression is a common mental disease affecting a lot of people of all ages around the world."1.51Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats. ( Abdelmelek, H; Ammari, M; Lassoued, A; Othman, H; Sakly, M, 2019)
"The observed withdrawal symptoms were too short a period of sleep after feeding (6), poor feeding (3), mild to severe tremors (6), hyperactive Moro reflex (3) and respiratory rate >60 breaths min(-1)."1.38Clomipramine concentration and withdrawal symptoms in 10 neonates. ( De Jong-van den Berg, LT; den Boon, J; Jansman, FG; Smit, JP; ter Horst, PG; van der Linde, S; van Lingen, RA; Wilffert, B, 2012)
"In teeth with ligature, mean alveolar bone loss varied from 0."1.35Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats. ( Gaio, EJ; Rosing, CK; Soletti, AC, 2009)
" These effects were similar to the effects induced for subchronic and chronic administration of the antidepressant fluoxetine (5 mg/kg sc), a selective serotonin re-uptake inhibitor."1.33Antidepressant effects of nicotine and fluoxetine in an animal model of depression induced by neonatal treatment with clomipramine. ( Bonilla-Jaime, H; Vázquez-Palacios, G; Velázquez-Moctezuma, J, 2005)
"Treatment with fluoxetine reversed these changes, as in SC rats."1.32Alterations in voiding frequency and cystometry in the clomipramine induced model of endogenous depression and reversal with fluoxetine. ( Dean-McKinney, T; Klausner, AP; Lee, KS; Na, YG; Steers, WD; Tuttle, JB, 2003)
" Chronic administration of cyclic antidepressant drugs (citalopram, clomipramine, imipramine) decreased the immunoreactivity of the up-regulated G alpha i2 protein (31%)."1.30Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment. ( Balant, L; Busquets, X; Escribá, PV; García-Sevilla, JA; Guimón, J; Walzer, C, 1997)
"Because of a depressive syndrome, a 39-year-old patient received 20 mg fluoxetine per day."1.29[A case of rare side effects of certain antidepressive drugs]. ( Haenel, T; Stöckli, HR; Truog, P, 1995)
"Because human endogenous depression is associated with abnormal REM sleep and an elevated nocturnal Tb, these results give further support for the validity of the CLI model of depression and provide insight into the relationships among Tb, Ta, REM sleep and depression."1.29The effects of a 3-day increase of ambient temperature on body temperature and REM sleep in an animal model of depression. ( Rosenthal, MS; Vogel, GW, 1994)
"One theory about the pathogenesis of endogenous depression is that decreased serotonergic (5-HT) neurotransmission is involved in producing the disorder."1.29Decreased raphe unit activity in a rat model of endogenous depression. ( Neill, DB; Vogel, GW; Yavari, P, 1993)
" For the remaining 29, a comparison with 29 Caucasian patients treated by clomipramine (the two samples are matched for sex and age, and the variables of weight, dosage and drug association are controlled) shows no significantly higher plasma levels in the Beninese sample."1.28Clomipramine plasma levels among depressed outpatients in Benin, west Africa: drug compliance and comparison with Caucasian patients. ( Bertschy, G; Vandel, S, 1992)
"Clomipramine is a chlorinated tricyclic antidepressant commonly used in the treatment of depression (1)."1.28Toxic neonatal effects following maternal clomipramine therapy. ( Katz, EZ; Koren, G; Pastuszak, A; Schimmell, MS; Shaag, Y, 1991)
"clomipramine was studied in seven drug-free depressed patients and seven age-matched healthy control subjects."1.28Abnormal neuroendocrine responsivity to acute i.v. clomipramine challenge in depressed patients. ( Ekstrom, D; Golden, RN; Hicks, R; Hsiao, JK; Lane, E; Potter, WZ; Rogers, S, 1990)
"This suggests that an animal model of endogenous depression should show diminished sexual activity."1.28Diminished sexual activity in a new animal model of endogenous depression. ( Hagler, M; Hennessey, A; Kors, D; Neill, D; Vogel, G, 1990)
" Potential implications of the proposed model-based approach include adaptation of the dosage regimen to individual characteristics at the very beginning of antidepressant therapy, and early detection of patients with impaired metabolising capacities."1.28Clomipramine metabolism. Model-based analysis of variability factors from drug monitoring data. ( Balant, LP; Balant-Gorgia, AE; Garrone, G; Gex-Fabry, M, 1990)
"Two cases of agranulocytosis occurring after addition of a butyrophenone to a course of phenothiazine treatment are reported and possible mechanisms for this interaction are discussed."1.28Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment. ( Kehoe, R; Young, A, 1989)
" A tapering schedule was carried out during a 12-day stay in the hospital in which the diazepam dosage was reduced by a fixed quantity every day, corresponding to about ten percent of the initial dosage."1.28Panic attacks and major depression after discontinuation of long-term diazepam abuse. ( Magni, G; Schifano, F, 1989)
"Total sleep deprivation (TSD) in depressive patients is known to produce sudden changes in mood, but the factors involved in these mood changes are poorly understood."1.28Observed behavior as a predictor of the response to sleep deprivation in depressed patients. ( Beersma, DG; Bouhuys, AL; van den Hoofdakker, RH, 1989)
" All patients were markedly improved when the daily dosage of the antidepressant was reduced with a simultaneous decrease of the blood concentrations."1.28High blood concentrations of imipramine or clomipramine and therapeutic failure: a case report study using drug monitoring data. ( Balant, LP; Balant-Gorgia, AE; Garrone, G, 1989)
"Ninety five patients with unipolar depression who received lithium therapy for one year were also studied."1.27Classification of depression and response to antidepressive therapies. ( Abou-Saleh, MT; Coppen, A, 1983)
"The reaction to sleep deprivation (SD) and the changes in MAO activity resulting from sleep deprivation were tested on 60 depressive patients as predictors for antidepressant drug treatment."1.27[When do I give which antidepressant in the individual case?]. ( Fähndrich, E, 1984)
"Although there have been previous reports of decreased sexual capacity as a side effect of antidepressants (1-3), the authors know of no previous records of increased capacity of the type described in the following reports, or of reports of side effects associated with yawning."1.27Unusual side effects of clomipramine associated with yawning. ( Forsythe, RG; Kapkin, IA; McLean, JD, 1983)
"25 patients with therapy-resistant depressive syndromes of various origins were treated by the infusion of high Hydiphen doses, a very effective thymoleptic drug with no dissociation between its drive increasing and spirit raising actions."1.27[Report of experiences with high dosage Hydiphen infusion treatment of depressive syndromes]. ( Dreves, B; Haiduk, A; Manthey, I; Schmieter, K, 1984)
"Clomipramine (CMI) was administered to eight patients, either as an antidepressive drug or, in two patients, as an antalgic drug (average age: 54 y."1.27[Plasma levels of desmethylclomipramine and clomipramine at steady-state in the morning. Correlative analysis and prediction of theoretical blood clomipramine]. ( Aymard, N; Champiat, JC; des Lauriers, A, 1983)
" Long-term administration of clomipramine was associated with decreases in platelet alpha 2-adrenoceptor densities which correlated with the duration of treatment."1.27Enhanced binding of [3H] (-) adrenaline to platelets of depressed patients with melancholia: effect of long-term clomipramine treatment. ( Alvarez, E; Casas, M; Fuster, MJ; Garcia-Sevilla, JA; Udina, C, 1987)
"Fengabine (SL 79."1.27Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. ( Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B, 1987)
"Lithium carbonate (600 mg/day) was then resumed."1.27[Rapid response of a disorder to the addition of lithium carbonate: panic resistant to tricyclic antidepressants]. ( Cournoyer, J, 1986)
"Seven patients suffering from severe endogenous depression who had proven resistant to lengthy trials of treatment with tricyclic and other antidepressants are described."1.27Clomipramine, tryptophan and lithium in combination for resistant endogenous depression: seven case studies. ( Bridges, PK; Hale, AS; Procter, AW, 1987)
"After four weeks 66% of the endogenous depressions and 53% of the exhaustion depressions had completely regressed."1.26[Management of treatment-resistant depression without ECT (author's transl)]. ( Adams, C; Gastpar, M; Kielholz, P; Terzani, S, 1981)
"Ten patients with a vital depressive syndrome were treated for 4 weeks with clomipramine (CI), five receiving the drug by mouth and five receiving it first intramuscularly and then by mouth."1.26Pharmacokinetics of clomipramine in depressive patients. ( de Cuyper, HJ; de Zeeuw, RA; Mulder-Hajonides, WR; van Praag, HM; Westenberg, HG, 1981)
"26 patients with depressive syndrome were included in a double-blind study; 13 patients were treated with clomipramine (CI) + placebo (P), and 13 with CI + PL."1.26Phospholipid liposomes in depression: a double-blind study versus placebo. ( Allegro, A; Casacchia, M; Cusimano, G; Di Cesare, E; Marola, W; Meco, G; Pirro, R, 1982)
" The third patient manipulated dosage times to diminish the orgastic problem."1.26Sexual dysfunction and clomipramine. ( Einarson, TR; Quirk, KC, 1982)
"Clomipramine is a tricyclic antidepressant widely used."1.26[Clomipramine and desmethylclomipramine: relationship between plasma levels and clinical effect (author's transl)]. ( Allers, G; Jounet, JM; Vandel, B; Vandel, S; Volmat, R, 1981)

Research

Studies (383)

TimeframeStudies, this research(%)All Research%
pre-1990156 (40.73)18.7374
1990's170 (44.39)18.2507
2000's39 (10.18)29.6817
2010's17 (4.44)24.3611
2020's1 (0.26)2.80

Authors

AuthorsStudies
Faucher, P1
Dries, A1
Mousset, PY1
Leboyer, M2
Dore, J1
Beracochea, D1
Brown, JT1
Schneiderhan, M1
Eum, S1
Bishop, JR1
Faye, A1
Kirpekar, V1
Tadke, R1
Gawande, S1
Bhave, S1
Tofte, A1
Narang, P1
Lippmann, S1
Gong, W1
Zhang, S1
Zong, Y1
Halim, M1
Ren, Z1
Wang, Y1
Ma, Y1
Li, B1
Ma, L1
Zhou, G1
Yu, J1
Zhang, J1
Liu, Q1
Othman, H1
Ammari, M1
Lassoued, A1
Sakly, M1
Abdelmelek, H1
Mumoli, N1
Cocciolo, M1
Vitale, J1
Mantellassi, M1
Sabatini, S1
Gambaccini, L1
Cei, M1
Kar, SK1
Garg, K1
Soletti, AC1
Gaio, EJ1
Rosing, CK1
Kuramochi, M1
Nakamura, S1
Matrisciano, F1
Modafferi, AM1
Togna, GI1
Barone, Y1
Pinna, G1
Nicoletti, F1
Scaccianoce, S1
Lagus, M1
Gass, N1
Saharinen, J1
Saarela, J1
Porkka-Heiskanen, T2
Paunio, T1
Lykouras, L1
Markianos, M1
Hatzimanolis, Y1
Perroud, N1
Bondolfi, G2
Uher, R1
Gex-Fabry, M3
Aubry, JM1
Bertschy, G4
Malafosse, A2
Kosel, M2
Couturier, PL1
Zahr, N1
Goldwirt, L1
Warot, D1
Allilaire, JF3
Lambrey, S1
ter Horst, PG1
van der Linde, S1
Smit, JP1
den Boon, J1
van Lingen, RA1
Jansman, FG1
De Jong-van den Berg, LT1
Wilffert, B1
McDowell, AL1
Strohl, KP1
Feng, P1
Savelyev, SA1
Rantamäki, T1
Rytkönen, KM1
Castren, E1
Wang, X1
Zeng, C1
Lin, J1
Chen, T1
Zhao, T1
Jia, Z1
Xie, X1
Qiu, Y1
Su, M1
Jiang, T1
Zhou, M1
Zhao, A1
Jia, W1
Licht, RW1
van Kampen, M1
Kramer, M1
Hiemke, C3
Flügge, G1
Fuchs, E1
Mavanji, V1
Datta, S1
Galeotti, N1
Bartolini, A1
Ghelardini, C1
Ventura, R1
Cabib, S1
Puglisi-Allegra, S1
Yamada, J1
Sugimoto, Y1
Braconnier, A1
Le Coent, R1
Cohen, D1
Zohar, J2
Keegstra, H1
Barrelet, L1
Mulder, RT5
Watkins, WG1
Joyce, PR6
Luty, SE1
Januel, D1
Poirier, MF3
D'alche-Biree, F1
Dib, M1
Olié, JP2
Hildebrandt, MG1
Steyerberg, EW1
Stage, KB3
Passchier, J1
Kragh-Soerensen, P1
Lee, KS1
Na, YG1
Dean-McKinney, T1
Klausner, AP1
Tuttle, JB1
Steers, WD1
Suzuki, E1
Yoshida, Y1
Shibuya, A1
Miyaoka, H1
Kozian, R1
Cordner, AP1
Herwood, MB1
Helmreich, DL1
Parfitt, DB1
Vandel, P1
Haffen, E1
Nezelof, S2
Broly, F2
Kantelip, JP1
Sechter, D3
Avella, J1
Lehrer, M1
Katz, M1
Minden, E1
Strobel, M1
Warnke, A1
Roth, M2
Schulze, U1
Vázquez-Palacios, G1
Bonilla-Jaime, H1
Velázquez-Moctezuma, J2
Inoue, T1
Kitaichi, T1
Ogawa, T1
Meco, G2
Bernardi, S1
Gruwez, B1
Dauphin, A1
Tod, M1
Bajbouj, M1
Gallinat, J1
Lang, UE1
Hellen, F1
Vesper, J1
Lisanby, SH1
Danker-Hopfe, H1
Neu, P1
Leggio, GM2
Micale, V2
Drago, F2
Bhagya, V1
Srikumar, BN1
Raju, TR1
Shankaranarayana Rao, BS1
Pfuhlmann, B1
Gerlach, M1
Burger, R1
Gonska, S1
Unterecker, S1
Jabs, B1
Riederer, P1
Deckert, J1
Yang, LM1
Hu, B1
Xia, YH1
Zhang, BL1
Zhao, H1
Bun'kova, KM1
Tamburella, A1
Mazzola, C1
Li Volsi, V1
Lecrubier, Y3
Puech, AJ1
Frances, H1
Jouvent, R4
Widlöcher, D3
Simon, P3
Kielholz, P4
Terzani, S2
Gastpar, M4
Adams, C2
Zapletálek, M2
Zbytovský, J2
Libiger, J1
Pazdírek, S1
Cápová, E1
Pöldinger, W1
Alac, S1
Krebs-Roubicek, E1
Bertilsson, L1
Tybring, G1
Braithwaite, R1
Träskman-Bendz, L1
Asberg, M4
Stewart, JW1
Quitkin, F1
Fyer, A1
Rifkin, A1
McGrath, P1
Liebowitz, M1
Rosnick, L1
Klein, DF1
Faravelli, C5
Ballerini, A3
Broadhurst, AD3
Das, M3
De Wilde, JE2
Doogan, DP1
Lechin, F1
Van der Dijs, B1
Gómez, F1
Arocha, L1
Acosta, E1
Lechin, E1
Abou-Saleh, MT1
Coppen, A1
Ambonetti, A2
Rapisarda, V1
Bongiorno, G1
Goyot, C2
Grenier, J2
Hug, R1
Cesková, E2
Náhunek, K2
Rysánek, R1
Svestka, J2
Marks, I1
Lader, M1
Boom, AJ1
Hevest, HP1
Krypsin-Exner, K1
van der Poel, FW1
Möller, HJ3
Kissling, W3
Herberger, B1
Kuss, HJ1
Kornhaber, A1
Horwitz, IM1
Puech, A1
Møller, SE5
Larsen, OB1
Gram, LF5
Kragh-Sørensen, P5
Kristensen, CB1
Møller, M1
Pedersen, OL2
Thayssen, P1
Nardini, M1
De Stefano, R1
Iannuccelli, M1
Borghesi, R1
Battistini, N1
Dimitriou, E1
Paraschos, A1
Logothetis, J1
Larsen, JK4
Holm, P3
Mikkelsen, PL1
Dick, P1
Ferrero, E1
Mertens, C1
Wakelin, JS1
Langer, G5
Aschauer, H3
Koinig, G5
Resch, F2
Schönbeck, G4
Keshavan, MS1
Dittrich, R1
Bech, P6
Allerup, P1
Reisby, N3
Wålinder, J1
Carlsson, A1
Persson, R1
Ortmann, J1
Elley, J1
Krautwald, O1
Klein, E1
Hefez, A1
Lavie, P1
Fähndrich, E7
Insel, TR3
Mueller, EA1
Gillin, JC1
Siever, LJ1
Murphy, DL2
Bottermann, P2
Yufu, N1
Itoh, M1
Notomi, A1
Nakao, H1
Brat, A1
Marchetti, G1
Franchi, F1
Padeletti, L1
Michelucci, A1
Pastorino, A1
McLean, JD1
Forsythe, RG1
Kapkin, IA1
Grillon, C1
Bathien, N1
Dreves, B1
Manthey, I1
Schmieter, K1
Haiduk, A1
Cowe, L1
Lloyd, DJ1
Dawling, S1
Coleman, BS1
Block, BA1
Kolomazník, M1
Hronek, J1
Petránová, T1
Jankových, V1
Karásková, M1
Kryl, L1
Stern, R1
Müller-Oerlinghausen, B1
De Biase, L1
La Malfa, G1
Champiat, JC1
Aymard, N3
des Lauriers, A1
Brown, WA2
Qualls, CB2
de Cuyper, HJ1
van Praag, HM1
Mulder-Hajonides, WR1
Westenberg, HG1
de Zeeuw, RA1
Pinder, RM1
Blum, A1
Stulemeijer, SM1
Barres, M1
Molczadzki, M1
Rigaud, A1
Charbaut, J1
Israel, L1
Kammerer, T1
Ananth, J2
Pecknold, JC1
van den Steen, N1
Engelsmann, F1
van Bemmel, AL1
van den Hoofdakker, RH6
de Buck, RP1
Mawson, D1
Marks, IM1
Ramm, L1
Küfferle, B1
Grünberger, J1
Ostergaard, GZ1
Pedersen, SE1
Dutt, JE1
Yassa, R1
Vandel, B3
Vandel, S5
Jounet, JM2
Allers, G2
Volmat, R2
Kudrnová, K1
Soucek, K1
Dugas, M1
Zarifian, E1
Le Heuzey, MF1
Regnier, N1
Durand, G1
Rovei, V1
Morselli, PL2
Casacchia, M1
Pirro, R1
Di Cesare, E1
Allegro, A1
Cusimano, G1
Marola, W1
Quirk, KC1
Einarson, TR1
Laakmann, G1
Haier, RJ1
Lange, E1
Riedel, C1
König, L1
Liefke, T1
Kursawe, H1
Agnoli, A2
Martucci, N2
Ciabatti, P1
Caratozzolo, P1
Rulli, V1
Sollecito, A1
Ehsanullah, RS1
Thorén, P1
Cronholm, B1
Jörnestedt, L1
Träskman, L1
Linnoila, M1
Seppala, T1
Mattila, MJ1
Vihko, R1
Pakarinen, A1
Skinner, T1
Rafaelsen, OJ1
Serfaty, MA1
McCluskey, S1
Eccleston, D1
Müller, B1
Andersen, JV1
Buch, D1
Bellino, S1
Barzega, G1
Bogetto, F1
Maina, G1
Ravizza, L1
Baischer, W1
Hartmann, B1
Huber, J1
Harris, MG1
Benfield, P1
Lamard, L1
Pérault, MC1
Bouquet, S2
Guibert, S1
Kupfer, DJ8
Pollock, BG8
Perel, JM8
Miewald, JM4
Grochocinski, VJ1
Ehlers, CL3
Sullivan, PF3
Kilonzo, GP1
Kaaya, SF1
Rweikiza, JK1
Kassam, M1
Moshi, G1
Ulrich, G2
Haug, HJ2
Wilens, TE1
Spencer, T1
Biederman, J1
Wozniak, J1
Connor, D1
Cano-Muñoz, JL1
Montejo-Iglesias, ML2
Yañez-Saez, RM1
Gálvez-Borrero, IM1
Haenel, T2
Stöckli, HR1
Truog, P1
Kubota, T1
Ishikura, T1
Jibiki, I1
van Hoof, JJ1
Hulstijn, W1
van Mier, H1
Pagen, M1
Ackerman, DL1
Greenland, S1
Bystritsky, A2
Morgenstern, H1
Katz, RJ2
Rosenthal, MS1
Vogel, GW2
Bocksberger, JP1
Gauthey, L1
Balant-Gorgia, AE6
Waikar, SV1
Honore, P1
Carbuccia, I1
Bowler, KA1
Noguchi, T1
Shimoda, K2
Takahashi, S2
Bagheri, H1
Picault, P1
Schmitt, L1
Houin, G1
Berlan, M1
Montastruc, JL1
Coutts, RT1
Alderman, CP1
Atchison, MM1
McNeece, JI1
Cloninger, CR1
Stöger, H1
Wilders-Truschnig, M1
Schmid, M1
Petek, W1
Samonigg, H1
Weizman, R1
Laor, N1
Podliszewski, E1
Notti, I1
Djaldetti, M1
Bessler, H1
Kojima, H1
Terao, T5
Yoshimura, R2
Nierenberg, DW1
Semprebon, M1
Tollefson, GD1
Souetre, E2
Thomander, L1
Potvin, JH1
Mine, K1
Okada, M1
Mishima, N1
Fujiwara, M1
Nakagawa, T1
Shioiri, T1
Kato, T1
Murashita, J1
Yamada, N1
Lejoyeux, M2
Rouillon, F1
Adès, J2
Balon, R1
Yeragani, VK1
Pohl, R1
Ramesh, C1
Yazici, O1
Aricioğlu, F1
Gürvit, G1
Uçok, A1
Taştaban, Y1
Canberk, O1
Ozgüroğlu, M1
Durat, T1
Sahin, D1
Yavari, P1
Neill, DB1
Phillips, KA2
McElroy, SL1
Keck, PE1
Pope, HG2
Hudson, JI1
Vila, G1
Mouren-Simeoni, MC1
Shapira, B3
Cohen, J1
Newman, ME2
Lerer, B3
Buchholtz-Hansen, PE1
Wang, AG1
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Jones, TT1
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Meyer, MC1
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Tucker, E1
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Baumann, P4
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Ninan, PT1
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Lalaude, O1
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Ducrotte, P1
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Teixidó Perramón, C1
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Kuźma, M1
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Boringa, JB1
de Jong, GM1
Touw, DJ1
François, TH1
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Newman, M1
Diaz Ruiz, O1
Fineberg, NA1
Bullock, T1
Montgomery, DB1
Montgomery, SA1
Fineyre, F1
Goodman, WK1
McDougle, CJ1
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Beersma, DG2
Anderson, IM1
Ware, CJ1
da Roza Davis, JM1
Cowen, PJ1
Manfredi, R1
Zhao, J1
Hasama, N1
Yamada, K1
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Mårtensson, B2
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Montero, D1
Dechant, KL1
Clissold, SP1
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Boulenger, JP1
Caillard, V1
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Bonnet, D1
Nisijima, K1
Hirayama, M1
Vallada, HP1
Gentil, V1
Solyom, L1
Solyom, C1
Ledwidge, B1
Nagano, K1
Ikezaki, A2
Tashiro, T2
Rampello, L1
Nicoletti, G1
Raffaele, R1
Anderson, J1
Bille, A1
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Høyer, E1
Jensen, H1
Mejlhede, A1
Langagergaard, A1
MacCrimmon, DJ1
Arató, M1
Saubadu, S1
Chen, CJ1
Noguera, R1
Altuna, R1
Ayuso, JL1
Casais, L1
Udina, C3
Jarrett, DB2
Pollock, B1
Naylor, MW1
Grossman, M1
Pakesch, G1
Dossenbach, M1
Bihari, K1
Pato, MT1
Hill, JL1
McEachran, AB1
Bjerrum, H1
Bøjholm, S1
Butler, B1
Folker, H1
Loldrup, D1
Hsiao, JK1
Lane, E1
Rogers, S1
Hicks, R1
Potter, WZ1
Mellerup, ET2
Plenge, P2
DeVeaugh-Geiss, J1
Trimble, MR1
Elsenga, S3
Beersma, D1
Tiller, JW1
Funke, HJ1
Moritz, E1
Hellstern, K3
Malanowski, H2
Civeira, J1
Cervera, S1
Giner, J1
Allen, SR1
Wirz, R1
Klar, K1
Dierick, M1
Cattiez, P1
Franck, G1
Burton, P1
Defleur, J1
Hermans, W1
Roelandts, A1
Wolfrum, C1
Berger, M4
D'haenen, H1
De Weert, D1
Feyaerts, M1
Nielsen, NP1
Cesana, B1
Zizolfi, S1
Ascalone, V1
Priore, P1
Price, J1
Grunhaus, LJ1
Chiu, S1
McFarlane, AH1
Dobson, N1
Flament, MF1
Koby, E1
Berg, CJ1
Zahn, T1
Cox, C1
Denckla, M1
Lenane, M1
Hartley, P1
Neill, D3
Hagler, M3
Kors, D3
Vogel, G3
Hennessey, A1
Riemann, D3
Fava, M1
Anderson, K1
Rosenbaum, JF1
Gehris, TL1
Kathol, RG1
Black, DW1
Noyes, R1
Goronzy, JJ1
Weyand, CM1
Garrone, G2
Van Sweden, B1
Gagiano, CA1
Müller, PG1
Fourie, J1
Le Roux, JF1
Guillibert, E1
Pelicier, Y2
Archambault, JC1
Chabannes, JP1
Clerc, G1
Desvilles, M1
Guibert, M1
Pagot, R1
Poisat, JL1
Thobie, Y1
Young, A1
Kehoe, R1
Schifano, F1
Magni, G3
Warneke, L1
Morgado, A1
Raoux, N1
Smith, M1
Nagano, H1
Fukuzako, H1
Hokazono, Y1
Tominaga, H1
Hirakawa, K1
Matsumoto, K1
Nathan, RS2
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Manna, V1
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Gloger, S1
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O'Ryan, F1
Cohen, L1
Codner, S1
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Orofiamma, B1
Palminteri, R1
Koczkas, C1
Karlsson, A1
Nagy, A1
Ose, E1
Pétursson, H1
Ulverås, L1
Wenedikter, O1
Linder, J1
Fyrö, B1
Pettersson, U1
Werner, S1
Bouhuys, AL1
Stiller, RL1
Curtis, GC1
Murray, JB1
Steardo, L1
Barone, P1
Monteleone, P1
Iovino, M1
Cardone, G1
Fuster, MJ1
Casas, M2
Lloyd, KG1
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Sanger, D1
Depoortere, H1
Bartholini, G1
Ramos-Brieva, JA1
Eberhard, G1
von Knorring, L1
Nilsson, HL1
Sundequist, U1
Björling, G1
Linder, H1
Svärd, KO1
Tysk, L1
Wendt, G2
Binz, U2
Cournoyer, J1
Cole, JO1
Baumgartner, A1
Gräf, KJ1
Kürten, I1
Feder, R1
Eikmeier, G1
Kuhlmann, R1
Stieglitz, RD1
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von Oefele, K1
Grohmann, R1
Hippius, H1
Rüther, E1
Pallanti, S1
Lieberman, JA1
Kane, JM1
Reife, R1
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Ngo Khac, T1
Gilsdorf, U1
Urbani, A1
Silvestro, A1
Grassetto, M1
Zysset, T1
Foa, EB1
Steketee, G1
Kozak, MJ1
Dugger, D1
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Naylor, GJ1
Sarrias, MJ1
Martínez, E1
Gelpí, E1
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Procter, AW1
Bridges, PK1
Riley, AJ1
Riley, EJ1
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von Frenckell, R1
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Brambilla, F1
Pugnetti, L1
Scarone, S1
Gambini, O1
Maggioni, M1
Nobile, P1
Christensen, P1
Thomsen, HY1
Rinsky, H1
Cygielman, G1
Ovuga, E1
Aapro, N1
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Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Motivational Interviewing to Reduce Substance Use Among Depression Patients[NCT02420561]307 participants (Actual)Interventional2010-10-31Completed
Silymarin Treatment of Body Dysmorphic Disorder: A Double-Blind, Placebo-Controlled, Cross-Over Study[NCT02843451]Phase 20 participants (Actual)Interventional2016-10-31Withdrawn (stopped due to Focus on other studies)
Quetiapine Augmentation Versus Clomipramine Augmentation of Selective Serotonin Reuptake Inhibitors for Obsessive-compulsive Disorder Patients That do Not Respond to a SSRI Trial: a Randomized Open-trial.[NCT00564564]Phase 421 participants (Actual)Interventional2006-01-31Completed
Efficacy and Safety Analyses of Mirtazapine in the Treatment of Malignant Tumor Related Depression: A Phase II, Placebo-controlled, Randomized, Double-blinded Clinical Trial in Advanced Non-small Cell Lung Cancer Patients[NCT02650544]Phase 2236 participants (Anticipated)Interventional2015-12-31Active, not recruiting
Study of Antidepressants in Parkinson's Disease[NCT00086190]Phase 3115 participants (Actual)Interventional2005-06-30Completed
Depression - Can Vitamin D Alleviate Symptoms of Depression Not Cured by Antidepressants as Well as Alleviate Negative Skeletal Effects Caused by Antidepressants?[NCT01932931]71 participants (Actual)Interventional2013-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Beck Depression Inventory II (BDI-II)

Beck Depression Inventory II ranges from 0-63. Higher score indicates more severe depression. 0-13 minimal depression, 14-19 mild depression, 20-28 moderate depression, 29-63 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in BDI-II score (Mean)
Paroxetine-9.7
Venlafaxine Extended Release-9.6
Placebo-5.2

Change in Brief Psychiatric Rating Scale (BPRS)

Brief Psychiatric Rating Scale. Maximum score 126. Higher score indicates greater psychiatric difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in BPRS score (Mean)
Paroxetine-9.0
Venlafaxine Extended Release-9.8
Placebo-4.4

Change in Geriatric Depression Rating Scale (GDS)

Geriatric Depression Scale ranges from 0-30. Higher score indicates more severe depression. 0-9 normal, 10-19 mild depression, 20-30 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in GDS score (Mean)
Paroxetine-6.9
Venlafaxine Extended Release-6.9
Placebo-2.8

Change in Hamilton Depression Rating Scale (HAM-D) Scores

Change in Hamilton Rating Scale for Depression over 12 weeks. Hamilton Depression Rating Scale ranges from 0-50. Higher scores represent more significant depression. Mild depression ranges from 8-13, moderate depression from 14-18, severe 19-22 and very severe any score over 23. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in HAM-D score (Mean)
Paroxetine-13.0
Venlafaxine Extended Release-11.0
Placebo-6.8

Change in Montgomery-Asberg Depression Rating Scale (MADRS)

Montgomery-Asberg Depression Rating Scale ranges from 0-60. Higher score indicates more severe depression. 0-6 normal, 7-19 mild depression, 20-34 moderate depression, greater than 34 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in MADRS score (Mean)
Paroxetine-13.6
Venlafaxine Extended Release-10.9
Placebo-6.6

Change in Parkinson's Disease Questionnaire (PDQ) - 39 - Emotional Well-Being

Parkinson's Disease Questionnaire (PDQ-39) - Emotional Well-Being maximum score 24, minimum score of 0.Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PDQ-39 Emotional score (Mean)
Paroxetine-21.4
Venlafaxine Extended Release-20.7
Placebo-10.9

Change in Parkinson's Disease Questionnaire (PDQ) - 39 - Overall

Parkinson's Disease Questionnaire (PDQ-39) Total. Range 0-100. Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PDQ-39 score (Mean)
Paroxetine-8.0
Venlafaxine Extended Release-8.4
Placebo-5.3

Change in Pittsburgh Sleep Quality Index (PSQI)

Pittsburgh Sleep Quality Index scores range from 0-21, with higher scores indicating severe sleep difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PQSI score (Mean)
Paroxetine-2.1
Venlafaxine Extended Release-2.6
Placebo-1.1

Change in Short Form 36 Health Survey - Mental Component Summary

Short Form 36 Health Survey. Range 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 mental score (Mean)
Paroxetine11.4
Venlafaxine Extended Release9.5
Placebo4.8

Change in Short Form 36 Health Survey - Mental Health

Short Form 36 Health Survey - Mental Health subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 Mental Health score (Mean)
Paroxetine16.7
Venlafaxine Extended Release17.4
Placebo9.7

Change in Short Form 36 Health Survey - Role-Emotional

Short Form 36 Health Survey - Emotional subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 Role score (Mean)
Paroxetine39.5
Venlafaxine Extended Release26.9
Placebo12.7

Change in Short Form 36 Health Survey - Vitality

Short Form 36 Health Survey - Vitality subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 vitality score (Mean)
Paroxetine13.5
Venlafaxine Extended Release9.1
Placebo4.7

Change in Snaith Clinical Anxiety Scale (CAS)

Snaith Clinical Anxiety Scale. Range 0-21. Higher scores indicate increased anxiety. Score greater than 8 indicates clinical anxiety. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in CAS score (Mean)
Paroxetine-3.6
Venlafaxine Extended Release-3.2
Placebo-2.4

Change in Unified Parkinson's Disease Rating Scale (UPDRS)

Unified Parkinson's Disease Rating Scale. Higher score indicates more severe Parkinson's disease symptoms. Total maximum = 176. Mental maximum = 52, Activities of Daily Living maximum = 52, Motor maximum = 72. Minimum = 0. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS score (Mean)
Paroxetine-8.7
Venlafaxine Extended Release-7.0
Placebo-4.3

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Bulbar

Unified Parkinson's Disease Rating Scale - Bulbar maximum score 24, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-Bulbar score (Mean)
Paroxetine-1.4
Venlafaxine Extended Release-1.4
Placebo-0.5

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Motor

Unified Parkinson's Disease Rating Scale - Motor has a maximum score of 72, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-motor score (Mean)
Paroxetine-4.3
Venlafaxine Extended Release-2.0
Placebo-1.0

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Tremor

Unified Parkinson's Disease Rating Scale - Tremor subscale ranges from 0-23. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-tremor score (Mean)
Paroxetine0.4
Venlafaxine Extended Release0.5
Placebo-0.6

Reviews

26 reviews available for clomipramine and Depression, Endogenous

ArticleYear
Serum clomipramine and desmethylclomipramine levels in a CYP2C19 and CYP2D6 intermediate metabolizer.
    Pharmacogenomics, 2017, Volume: 18, Issue:7

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CY

2017
[Therapeutic strategy for drug resistant depression].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2004, Volume: 106, Issue:8

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Bupropion; Clomipramine; Depressive Disorder; D

2004
[Current treatment of depression].
    Therapeutische Umschau. Revue therapeutique, 1983, Volume: 40, Issue:9

    Topics: Administration, Oral; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Depression; Depress

1983
Are there anticompulsive or antiphobic drugs? Review of the evidence.
    The British journal of psychiatry : the journal of mental science, 1983, Volume: 143

    Topics: Adult; Antidepressive Agents; Child; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle

1983
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9 Pt 2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder

1983
Tryptophan and tyrosine availability: relation to clinical response to antidepressive pharmacotherapy.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Amitriptyline; Antidepressive Agents; Clomipramine; Depressive Disorder; Humans; Imipramine; Lithium

1984
Plasma level monitoring of antidepressants: theoretical basis and clinical application.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Genetic Variatio

1984
Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in older patients with depressive illness.
    Drugs & aging, 1995, Volume: 6, Issue:1

    Topics: Aged; Amitriptyline; Clomipramine; Depressive Disorder; Drug Interactions; Fluoxetine; Humans; Rando

1995
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
    Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:1

    Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug In

1994
Morbid jealousy as a variant of obsessive-compulsive disorder.
    The Australian and New Zealand journal of psychiatry, 1997, Volume: 31, Issue:1

    Topics: Anxiety Disorders; Clomipramine; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressive

1997
Mirtazapine: clinical advantages in the treatment of depression.
    Journal of clinical psychopharmacology, 1997, Volume: 17 Suppl 1

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine

1997
Antidepressants in the treatment of premenstrual dysphoric disorder.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 14

    Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclohexanols; Depressive Diso

1997
Clinical application of time-dependent sensitization to antidepressant therapy.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Drug Administration Schedule; Ele

1998
Child and adolescent mood disorders--experience with serotonin-based therapies.
    Biological psychiatry, 1998, Sep-01, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Child; Clomipramine; Depressive Disorder; Humans; Selective Serotonin Reuptake In

1998
Mirtazapine: clinical overview.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Adrenergic alpha-Antagonists; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Controlled Clini

1999
Evolution of remission as the new standard in the treatment of depression.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 22

    Topics: Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclohexanols; Depressive Disorder; F

1999
The functional anatomy, neurochemistry, and pharmacology of anxiety.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 22

    Topics: Adrenergic Uptake Inhibitors; Amygdala; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clomipram

1999
Serotonin reuptake inhibitors are the treatment of choice in obsessive compulsive disorder.
    International clinical psychopharmacology, 1992, Volume: 7 Suppl 1

    Topics: 1-Naphthylamine; Behavior Therapy; Clomipramine; Combined Modality Therapy; Depressive Disorder; Flu

1992
Pharmacotherapy of obsessive compulsive disorder.
    The Journal of clinical psychiatry, 1992, Volume: 53 Suppl

    Topics: 1-Naphthylamine; Antidepressive Agents; Clomipramine; Depressive Disorder; Fluoxetine; Fluvoxamine;

1992
Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.
    Drugs, 1991, Volume: 41, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Drug Evaluation; D

1991
Worldwide use of clomipramine.
    The Journal of clinical psychiatry, 1990, Volume: 51 Suppl

    Topics: Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1990
Tryptophan to competing amino acids ratio in depressive disorder: relation to efficacy of antidepressive treatments.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 325

    Topics: Amino Acids; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Clomipramine; Depressive

1985
Successful treatment of obsessive-compulsive disorders.
    Genetic, social, and general psychology monographs, 1986, Volume: 112, Issue:2

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Behavior Therapy; Clomipramine; Depressive Disorder; Ele

1986
Neuromuscular effects of monoamine oxidase inhibitors.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adult; Animals; Clomipramine; Clorgyline; Depressive Disorder; Female; Humans;

1986
Clomipramine: an antiobsessive drug.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:3

    Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D

1986
Obsessive-compulsive disorder.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Clo

1985

Trials

133 trials available for clomipramine and Depression, Endogenous

ArticleYear
Is it possible to evaluate true prophylactic efficacy of antidepressants in severely ill patients with recurrent depression? Lessons from a placebo-controlled trial. The fifth trial of the Danish University Antidepressant Group (DUAG-5).
    Journal of affective disorders, 2013, Volume: 148, Issue:2-3

    Topics: Antidepressive Agents; Citalopram; Clomipramine; Denmark; Depressive Disorder; Double-Blind Method;

2013
Paroxetine versus clomipramine in adolescents with severe major depression: a double-blind, randomized, multicenter trial.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depressive Disorder; Doubl

2003
Fluvoxamine as effective as clomipramine against symptoms of severe depression: results from a multicentre, double-blind study.
    Human psychopharmacology, 2003, Volume: 18, Issue:2

    Topics: Adult; Antidepressive Agents; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; D

2003
Age may affect response to antidepressants with serotonergic and noradrenergic actions.
    Journal of affective disorders, 2003, Volume: 76, Issue:1-3

    Topics: Adolescent; Adult; Age Factors; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agent

2003
Multicenter double-blind randomized parallel-group clinical trial of efficacy of the combination clomipramine (150 mg/day) plus lithium carbonate (750 mg/day) versus clomipramine (150 mg/day) plus placebo in the treatment of unipolar major depression.
    Journal of affective disorders, 2003, Volume: 76, Issue:1-3

    Topics: Administration, Oral; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipra

2003
Are gender differences important for the clinical effects of antidepressants?
    The American journal of psychiatry, 2003, Volume: 160, Issue:9

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Double-B

2003
Nitric oxide involvement in depression during interferon-alpha therapy.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorde

2003
Clomipramine, fluoxetine and CYP2D6 metabolic capacity in depressed patients.
    Human psychopharmacology, 2004, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic;

2004
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Ther

2007
Efficacy of desipramine in endogenomorphically depressed patients.
    Journal of affective disorders, 1980, Volume: 2, Issue:3

    Topics: Adjustment Disorders; Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder

1980
Fluvoxamine and chlorimipramine in endogenous depression.
    Journal of affective disorders, 1982, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Bipolar Disorder; Clomipramine; Depressive Disorder; Doubl

1982
Double blind test with mianserin versus chlorimipramine.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Adolescent; Adult; beta-Endorphin; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Dibe

1982
[Clinical experience with clomipramine (Hydiphen) and desipramine (Petytyl) by parenteral administration in the treatment of endogenous depression with signs of pharmacoresistance].
    Ceskoslovenska psychiatrie, 1983, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Desipramine; D

1983
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9 Pt 2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder

1983
[Delayed-action clomipramine tablets in 78 ambulatory depressive patients: a double-blind study].
    Therapeutische Umschau. Revue therapeutique, 1983, Volume: 40, Issue:9

    Topics: Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Clomipramine; Delayed-Action Preparations; D

1983
[Controlled study on the possible benefits of combination therapy with chlorimipramine and haloperidol inpatients with endogenous depression].
    Pharmacopsychiatry, 1984, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Drug Combinati

1984
A comparison of clomipramine and doxepin in neurotic depression.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1984
Beta-receptor stimulation in the treatment of depression.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Affective Disorders, Psychotic; Albuterol; Bipolar Disorder; Clinical Trials as Topic; Clomipramine;

1984
Treatment of depression with L-5-hydroxytryptophan combined with chlorimipramine, a double-blind study.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Doubl

1983
A double-blind comparison of lofepramine and clomipramine in depressed outpatients.
    Psychopharmacology bulletin, 1984,Fall, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Dibenzazepines

1984
Moclobemide and clomipramine in the treatment of depression. A randomized clinical trial.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:3

    Topics: Adult; Aged; Benzamides; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Dizziness; Dou

1984
A double-blind comparative study of the clinical efficacy of fluvoxamine and chlorimipramine.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 3

    Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Bl

1983
Clinical trials of fluvoxamine vs chlorimipramine with single and three times daily dosing.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Clomipra

1983
Assessment of symptom change from improvement curves on the Hamilton depression scale in trials with antidepressants.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder; Female; Humans; Imipramine; M

1984
Fluvoxamine maleate, a serotonergic antidepressant; a comparison with chlorimipramine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:4-6

    Topics: Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Clomipramine; Depressive Disorder

1982
A double-blind multicentre trial comparing the efficacy and side-effects of mianserin and chlorimipramine in depressed in- and outpatients.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Aged; Body Weight; Clinical Trials as Topic; Clomipramine; Depressive Disorder; D

1980
Double-blind comparative study of clomipramine and amitriptyline in obsessive neurosis.
    Progress in neuro-psychopharmacology, 1981, Volume: 5, Issue:3

    Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder

1981
Maintenance of therapeutic effects of total sleep deprivation by limitation of subsequent sleep. A pilot study.
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:5

    Topics: Clinical Trials as Topic; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Pilo

1981
[Analysis of controlled studies comparing mianserin and clomipramine (author's transl)].
    L'Encephale, 1981, Volume: 7, Issue:4 Suppl

    Topics: Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Dibenzazepines; Double-Bli

1981
Clomipramine and exposure for chronic obsessive-compulsive rituals: III. Two year follow-up and further findings.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Anxiety; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; F

1982
Early clinical double-blind study with S-adenosyl-L-methionine: a new potential antidepressant.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Bl

1982
Relationship between the plasma concentration of clomipramine and desmethylclomipramine in depressive patients and the clinical response.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Adult; Aged; Biotransformation; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged

1982
Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial.
    Archives of general psychiatry, 1980, Volume: 37, Issue:11

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Nortriptyline; Obsessiv

1980
Clomipramine and doxepin in depressive neurosis. Plasma levels and therapeutic response.
    Archives of general psychiatry, 1980, Volume: 37, Issue:11

    Topics: Adult; Clomipramine; Depressive Disorder; Doxepin; Female; Humans; Male; Reaction Time; Tryptophan

1980
Moclobemide versus clomipramine in depressed patients in general practice. A randomized, double-blind, parallel, multicenter study.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:4 Suppl 2

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Clomipramine; Depr

1995
Hypothalamic-pituitary-gonadal axis in depressed premenopausal women: elevated blood testosterone concentrations compared to normal controls.
    Psychoneuroendocrinology, 1995, Volume: 20, Issue:5

    Topics: Adult; Clomipramine; Depressive Disorder; Estradiol; Female; Gonadal Steroid Hormones; Humans; Hypot

1995
[Cytochrome p450 IID6, its role in psychopharmacology].
    Annales medico-psychologiques, 1995, Volume: 153, Issue:2

    Topics: Adolescent; Adult; Aged; Clomipramine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Depr

1995
Effect of pulse loading with clomipramine on EEG sleep.
    Psychiatry research, 1994, Volume: 54, Issue:2

    Topics: Adult; Clinical Protocols; Clomipramine; Delta Rhythm; Depressive Disorder; Dose-Response Relationsh

1994
Effects of exclusion criteria in depression treatment studies.
    Journal of affective disorders, 1994, Volume: 32, Issue:1

    Topics: Adult; Clomipramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Ps

1994
Determination of appropriate clomipramine dosage among depressed African outpatients in Dar es Salaam, Tanzania.
    The Central African journal of medicine, 1994, Volume: 40, Issue:7

    Topics: Administration, Oral; Adult; Analysis of Variance; Black People; Clomipramine; Depressive Disorder;

1994
Relationships of the Tridimensional Personality Questionnaire to mood and personality measures for depressed patients.
    Psychological reports, 1994, Volume: 75, Issue:3 Pt 1

    Topics: Adolescent; Adult; Affect; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female;

1994
Predictors of treatment response in obsessive-compulsive disorder: multivariate analyses from a multicenter trial of clomipramine.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Age Factors; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged

1994
Inert placebo versus active medication. Patient blindability in clinical pharmacological trials.
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:9

    Topics: Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Humans; Obsessive-

1994
Early response patterns associated with successful clomipramine treatment.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:6

    Topics: Adult; Clomipramine; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; Human

1993
Pharmacokinetic study of yohimbine and its pharmacodynamic effects on salivary secretion in patients treated with tricyclic antidepressants.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:1

    Topics: Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressi

1994
Temperament predicts clomipramine and desipramine response in major depression.
    Journal of affective disorders, 1994, Volume: 30, Issue:1

    Topics: Adult; Clomipramine; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Female; Hum

1994
Changes in the frequency distribution pattern of body weight in patients with major depression.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine

1993
Prospective evaluation of the serotonin syndrome in depressed inpatients treated with clomipramine.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arousal; Brain; Clomipramine; Depressive Disorder; Female; Humans; M

1993
Moclobemide: a reversible MAO-A-inhibitor showing weaker antidepressant effect than clomipramine in a controlled multicenter study. Danish University Antidepressant Group.
    Journal of affective disorders, 1993, Volume: 28, Issue:2

    Topics: Adult; Aged; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Half-Life;

1993
Noradrenergic and serotoninergic depression?
    Journal of affective disorders, 1993, Volume: 27, Issue:2

    Topics: Adult; Aged; Brain; Clomipramine; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Maprot

1993
Plasma amino acid profiles in relation to clinical response to moclobemide in patients with major depression. Danish University Antidepressant Group.
    Journal of affective disorders, 1993, Volume: 27, Issue:4

    Topics: Adult; Aged; Amino Acids; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Method; Female

1993
Prolactin response to fenfluramine and placebo challenge following maintenance pharmacotherapy withdrawal in remitted depressed patients.
    Biological psychiatry, 1993, Apr-01, Volume: 33, Issue:7

    Topics: Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Fenfluramine; Follow-Up Studie

1993
Mortality in major affective disorder: relationship to subtype of depression. The Danish University Antidepressant Group.
    Acta psychiatrica Scandinavica, 1993, Volume: 87, Issue:5

    Topics: Adult; Aged; Citalopram; Clomipramine; Denmark; Depressive Disorder; Female; Follow-Up Studies; Huma

1993
Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:11

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Clomipramine; Cross-Over Studies; Death, Sudden

1995
Combination treatment with clomipramine and fluvoxamine: drug monitoring, safety, and tolerability data.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:6

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dose-Response Rela

1996
The effect of a history of conduct disorder in adult major depression.
    Journal of affective disorders, 1996, Feb-12, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Child; Child Behavior Disorders; Cl

1996
Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients.
    Pharmacological research, 1995, Volume: 31, Issue:6

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Clomipramine; Depressive Disorder; Drug Interactions; Fe

1995
Estimation of the time course of slow-wave sleep over the night in depressed patients: effects of clomipramine and clinical response.
    Biological psychiatry, 1996, Feb-01, Volume: 39, Issue:3

    Topics: Administration, Oral; Adult; Antidepressive Agents; Circadian Rhythm; Clomipramine; Depressive Disor

1996
Screening and treating depressed patients. A comparison of two controlled citalopram trials across treatment settings: hospitalized patients vs. patients treated by their family doctors. Danish University Antidepressant Group.
    Acta psychiatrica Scandinavica, 1996, Volume: 94, Issue:1

    Topics: Citalopram; Clomipramine; Depressive Disorder; Family Practice; Female; Humans; Imipramine; Male; Ob

1996
Moclobemide versus clomipramine in nonmelancholic, nonpsychotic major depression. A Study group.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:4

    Topics: Adolescent; Adult; Aged; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Method; Female;

1995
A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease.
    The Journal of neuropsychiatry and clinical neurosciences, 1996,Summer, Volume: 8, Issue:3

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Antidepressive Agents, Tricyclic; Clomipramine;

1996
Initial increase of plasma serotonin: a biological predictor for the antidepressant response to clomipramine?
    Biological psychiatry, 1996, Sep-15, Volume: 40, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Biomarkers; Blood P

1996
Intimate bonds in depression.
    Journal of affective disorders, 1996, Oct-14, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Desipramine;

1996
Serotonin syndrome during clomipramine monotherapy: comparison of two diagnostic criteria.
    Psychiatry and clinical neurosciences, 1997, Volume: 51, Issue:1

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Psychoses, Substance-In

1997
The Major Depression Rating Scale (MDS). Inter-rater reliability and validity across different settings in randomized moclobemide trials. Danish University Antidepressant Group.
    Journal of affective disorders, 1997, Volume: 42, Issue:1

    Topics: Antidepressive Agents; Benzamides; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Hum

1997
A double-blind, multicenter study in primary care comparing paroxetine and clomipramine in patients with depression and associated anxiety. Paroxetine Study Group.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anxiety Disorders; Clomipramine; Comorbidity; Depress

1997
Pulse intravenous clomipramine for depressed adolescents: double-blind, controlled trial.
    The American journal of psychiatry, 1997, Volume: 154, Issue:5

    Topics: Adolescent; Age Factors; Ambulatory Care; Clomipramine; Depressive Disorder; Double-Blind Method; Fe

1997
Effects of clomipramine on plasma amino acids and serotonergic parameters in panic disorder and depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1997, Volume: 7, Issue:3

    Topics: Adult; Amino Acids; Antidepressive Agents, Tricyclic; Blood Platelets; Clomipramine; Depressive Diso

1997
Clomipramine augmentation in treatment-resistant depression.
    Depression and anxiety, 1997, Volume: 5, Issue:2

    Topics: Adult; Aged; Akathisia, Drug-Induced; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Sq

1997
Monitoring serum concentrations of clomipramine and metabolites: fluorescence polarization immunoassay versus high performance liquid chromatography.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Depressive Dis

1997
Long-term efficacy and safety of milnacipran compared to clomipramine in patients with major depression.
    Acta psychiatrica Scandinavica, 1997, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Clomipramine; Cyclopropanes; Depressive Disorder; Do

1997
A double-blind six months comparative study of milnacipran and clomipramine in major depressive disorder.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:5

    Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Constipation; Cyclopropanes; Depressive Disorder;

1997
A double-blind, comparative study of dothiepin and clomipramine in the treatment of major depressive illness.
    International journal of clinical practice, 1997, Volume: 51, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dothiepin; Double-Blind

1997
The effect of clinical outcome on platelet G proteins of major depressed patients.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1998, Volume: 8, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Blood Platelets;

1998
Dimensional assessment of onset of action of antidepressants: a comparative study of moclobemide vs. clomipramine in depressed patients with blunted affect and psychomotor retardation.
    Psychiatry research, 1998, Jul-13, Volume: 79, Issue:3

    Topics: Adult; Affective Symptoms; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Tricy

1998
Parenteral clomipramine challenge in depressed adolescents: mood and neuroendocrine response.
    Biological psychiatry, 1998, Oct-01, Volume: 44, Issue:7

    Topics: Adolescent; Affect; Clomipramine; Depressive Disorder; Female; Growth Hormone; Humans; Infusions, Pa

1998
The cortical serotonin2 receptors studied with positron-emission tomography and [18F]-setoperone during depressive illness and antidepressant treatment with clomipramine.
    Biological psychiatry, 1999, Jan-15, Volume: 45, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Binding Sites; Brain; Clomipramine; Depressive Disorder; Female;

1999
Combined treatment with venlafaxine and tricyclic antidepressants in depressed patients who had partial response to clomipramine or imipramine: initial findings.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Cyc

2000
A randomized, double-blind, parallel-group comparison of venlafaxine and clomipramine in outpatients with major depression.
    Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic;

1998
A double-blind study of the efficacy and safety of sertraline and clomipramine in outpatients with severe major depression.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:5

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disor

2000
Intravenous clomipramine decreases excitability of human motor cortex. A study with paired magnetic stimulation.
    Journal of the neurological sciences, 2001, Feb-15, Volume: 184, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depression, Chemical; Depressive Disorder; El

2001
Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function.
    Psychopharmacology, 1992, Volume: 109, Issue:1-2

    Topics: Adenylyl Cyclases; Alprostadil; Blood Platelets; Cell Membrane; Clomipramine; Colforsin; Depressive

1992
The efficacy of reversible monoamine oxidase inhibitors in depressive illness.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37 Suppl 1

    Topics: Antidepressive Agents, Tricyclic; Benzamides; Clomipramine; Depressive Disorder; Humans; Imipramine;

1992
Clomipramine versus phenelzine in obsessive-compulsive disorder. A controlled clinical trial.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Adult; Clomipramine; Depressive Disorder; Dexamethasone; Dose-Response Relationship, Drug; Double-Bl

1992
Effect of clomipramine and lithium on fenfluramine-induced hormone release in major depression.
    Biological psychiatry, 1992, May-15, Volume: 31, Issue:10

    Topics: Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combi

1992
Moclobemide versus clomipramine in endogenous depression. A double-blind randomised clinical trial.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Adult; Aged; Antidepressive Agents; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Meth

1992
[Psychopathologic and psychophysiologic follow-up of inpatient depressed patients with standardized treatment with clomipramine and oxaprotiline].
    Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1991, Volume: 142, Issue:3

    Topics: Adult; Antidepressive Agents; Arousal; Clomipramine; Depressive Disorder; Dose-Response Relationship

1991
Compared efficacy of prazepam and clomipramine in major depression with anxiety: a multicenter controlled study.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Child; Clomipramine; Depressive Disorder; Double-Blind Method; Fem

1991
Dopaminergic hypothesis for retarded depression: a symptom profile for predicting therapeutical responses.
    Acta psychiatrica Scandinavica, 1991, Volume: 84, Issue:6

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arousal; Brain; Clomipramine; Depres

1991
Moclobemide in depression: a randomized, multicentre trial against isocarboxazide and clomipramine emphasizing atypical depression.
    Acta psychiatrica Scandinavica, 1991, Volume: 84, Issue:6

    Topics: Adult; Aged; Antidepressive Agents; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Meth

1991
[Amoxapine and clomipramine. A controlled multicenter study in patients with major depression].
    L'Encephale, 1991, Volume: 17 Spec No 3

    Topics: Adult; Amoxapine; Clomipramine; Demography; Depressive Disorder; Double-Blind Method; Drug Evaluatio

1991
Fluoxetine vs. clomipramine in depressed patients: a controlled multicentre trial.
    Journal of affective disorders, 1991, Volume: 22, Issue:3

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Mal

1991
[Treatment of drug-resistant depression by intravenous administration of antidepressants].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:4

    Topics: Administration, Oral; Anthracenes; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Dibe

1990
Acute effect of intravenous clomipramine upon sleep-related hormone secretion in depressed outpatients and healthy control subjects.
    Biological psychiatry, 1991, Jan-01, Volume: 29, Issue:1

    Topics: Adult; Circadian Rhythm; Clomipramine; Depressive Disorder; Female; Growth Hormone; Humans; Hydrocor

1991
[Efficacy and safety of fluoxetine versus clomipramine in ambulatory patients with a depressive syndrome in a clinical trial with private practitioners].
    Wiener klinische Wochenschrift, 1991, Volume: 103, Issue:6

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Double-Blind Method; Family Practice; Female; Fluoxe

1991
Plasma ratio tryptophan/neutral amino acids in relation to clinical response to paroxetine and clomipramine in patients with major depression.
    Journal of affective disorders, 1990, Volume: 18, Issue:1

    Topics: Adult; Aged; Amino Acids; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind

1990
Paroxetine: a selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study. Danish University Antidepressant Group.
    Journal of affective disorders, 1990, Volume: 18, Issue:4

    Topics: Adult; Antidepressive Agents; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans

1990
The antiobsessional effects of clomipramine do not require concomitant affective disorder.
    Psychiatry research, 1990, Volume: 31, Issue:2

    Topics: Adult; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Multicenter Stu

1990
Worldwide use of clomipramine.
    The Journal of clinical psychiatry, 1990, Volume: 51 Suppl

    Topics: Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1990
Total and partial sleep deprivation in clomipramine-treated endogenous depressives.
    Journal of psychiatric research, 1990, Volume: 24, Issue:2

    Topics: Body Temperature Regulation; Clomipramine; Combined Modality Therapy; Depressive Disorder; Electroen

1990
Antidepressants, alcohol and psychomotor performance.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; Dose-Response Relations

1990
Moclobemide versus clomipramine in the treatment of depression: a single-centre study, Federal Republic of Germany.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Antidepressive Agents; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Method; Germany;

1990
Moclobemide versus clomipramine in the treatment of depression: a multicentre trial in Spain.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Adult; Antidepressive Agents; Benzamides; Clomipramine; Depressive Disorder; Dose-Response Relations

1990
Moclobemide versus clomipramine in the treatment of depression: a double-blind multicentre study in Belgium.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Antidepressive Agents; Belgium; Benzamides; Clomipramine; Depressive Disorder; Double-Blind Method;

1990
Therapeutic effects of fengabine, a new GABAergic agent, in depressed outpatients: a double-blind study versus clomipramine.
    Acta psychiatrica Scandinavica, 1990, Volume: 82, Issue:5

    Topics: Adult; Antidepressive Agents; Chlorophenols; Clomipramine; Depressive Disorder; Double-Blind Method;

1990
Urinary free cortisol levels in obsessive-compulsive disorder.
    Psychiatry research, 1990, Volume: 32, Issue:2

    Topics: Adult; Clomipramine; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middl

1990
The therapeutic efficacy of paroxetine: (a) an open study in patients with major depression not responding to antidepressants; (b) a double-blind comparison with amitriptyline in depressed outpatients.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 350

    Topics: Aged; Antidepressive Agents; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Administra

1989
A double-blind, multicentre study of paroxetine versus clomipramine in depressed elderly patients.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 350

    Topics: Aged; Antidepressive Agents; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans;

1989
Acute antidepressant effect following pulse loading with intravenous and oral clomipramine.
    Archives of general psychiatry, 1989, Volume: 46, Issue:1

    Topics: Administration, Oral; Adult; Biological Availability; Clinical Trials as Topic; Clomipramine; Depres

1989
Fluoxetine in endogenous depression and melancholia versus clomipramine.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Male; Mid

1989
Double-blind controlled study on the clinical efficacy and safety of fluoxetine vs clomipramine in the treatment of major depressive disorders.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Flu

1989
Fluoxetine versus clomipramine in major depressive disorders.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Chemical Phenomena; Chemistry; Clomipramine; Depressive Disorder; Double-Blind Method; Female

1989
Panic attacks and agoraphobia: low dose clomipramine treatment.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressiv

1989
Fengabine, a new GABAmimetic agent in the treatment of depressive disorders: an overview of six double-blind studies versus tricyclics.
    Neuropsychobiology, 1989, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar D

1989
Moclobemide and clomipramine in endogenous depression. A randomized clinical trial.
    Acta psychiatrica Scandinavica, 1989, Volume: 79, Issue:6

    Topics: Adult; Aged; Antidepressive Agents; Benzamides; Clinical Trials as Topic; Clomipramine; Depressive D

1989
Acute antidepressant effect of lithium is associated with fluctuation of calcium and magnesium in plasma. A double-blind study on the antidepressant effect of lithium and clomipramine.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:1

    Topics: Adult; Calcium; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Fe

1989
Clomipramine and EEG sleep in depression.
    Psychiatry research, 1989, Volume: 30, Issue:2

    Topics: Administration, Oral; Adult; Clomipramine; Depressive Disorder; Double-Blind Method; Electroencephal

1989
Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicenter study. Danish University Antidepressant Group.
    Psychopharmacology, 1986, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents; Citalopram; Clinical Trials as Topic; Clomipramine; Depres

1986
Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology.
    Biological psychiatry, 1987, Volume: 22, Issue:6

    Topics: Adult; Brain; Clomipramine; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; Human

1987
Therapeutic effect of maprotiline and chlorimipramine: controlled study.
    Neuropsychobiology, 1988, Volume: 19, Issue:1

    Topics: Adult; Anthracenes; Bipolar Disorder; Clinical Trials as Topic; Clomipramine; Depressive Disorder; F

1988
A double-blind randomized study of clomipramine versus maprotiline in patients with idiopathic pain syndromes.
    Neuropsychobiology, 1988, Volume: 19, Issue:1

    Topics: Adult; Aged; Anthracenes; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind

1988
CGP 12.103 A versus clomipramine in the treatment of depressed inpatients--results of a double-blind study.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:4

    Topics: Anthracenes; Antidepressive Agents; Blood Pressure; Clinical Trials as Topic; Clomipramine; Depressi

1988
Where are those new antidepressants we were promised?
    Archives of general psychiatry, 1988, Volume: 45, Issue:2

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Human

1988
Double-blind study of oxaprotiline versus clomipramine in the treatment of depressive inpatients.
    Neuropsychobiology, 1987, Volume: 17, Issue:1-2

    Topics: Adult; Aged; Anthracenes; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind

1987
Clomipramine: an antiobsessive drug.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:3

    Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D

1986
Experiments on clinical observation and judgement in the assessment of depression: profiled videotapes and Judgement Analysis.
    Psychological medicine, 1986, Volume: 16, Issue:4

    Topics: Adult; Citalopram; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1986
Comparison of oral and intravenous treatment of depressive states: preliminary results of a WHO collaborative study.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 4

    Topics: Administration, Oral; Anthracenes; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Huma

1986
Effects of imipramine on depression and obsessive-compulsive symptoms.
    Psychiatry research, 1987, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Clomipramine; Depressive Disorder; Humans; Imipramine; Middle Aged; Obsessi

1987
Biological predictors of success of antidepressant drug therapy.
    Psychiatric developments, 1987,Summer, Volume: 5, Issue:2

    Topics: Age Factors; Anthracenes; Circadian Rhythm; Clomipramine; Depressive Disorder; Drug Administration S

1987
Tricyclic antidepressants in obsessive-compulsive disorder: antiobsessional or antidepressant agents? II.
    The American journal of psychiatry, 1985, Volume: 142, Issue:5

    Topics: Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Hum

1985
Obsessive-compulsive disorder.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Clo

1985
Orthostatic side effects of clomipramine and citalopram during treatment for depression.
    Psychopharmacology, 1985, Volume: 86, Issue:4

    Topics: Adult; Citalopram; Clomipramine; Depressive Disorder; Female; Humans; Hypotension, Orthostatic; Male

1985
Amineptine in the management of the depressive syndromes.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:4

    Topics: Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipramine; Depressi

1985

Other Studies

228 other studies available for clomipramine and Depression, Endogenous

ArticleYear
Synergistic effects of
    Beneficial microbes, 2022, Aug-03, Volume: 13, Issue:3

    Topics: Animals; Clomipramine; Curcumin; Depression; Depressive Disorder; Disease Models, Animal; Glutamine;

2022
Obsession of pregnancy: Does it exist?
    Asian journal of psychiatry, 2017, Volume: 29

    Topics: Attitude to Health; Citalopram; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Depressive D

2017
In the Mirror: Depression With Dysmorphia and Obsessive-Compulsive Disorder.
    The primary care companion for CNS disorders, 2018, Oct-11, Volume: 20, Issue:5

    Topics: Adult; Body Dysmorphic Disorders; Clomipramine; Depressive Disorder; Face; Female; Humans; Obsessive

2018
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
    Journal of affective disorders, 2019, 07-01, Volume: 254

    Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Clomipramine; Cytokines; Depression; Depre

2019
Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats.
    Behavioural brain research, 2019, 11-18, Volume: 374

    Topics: Animals; Antidepressive Agents; Clomipramine; Depression; Depressive Disorder; Disease Models, Anima

2019
Diabetes mellitus associated with clomipramine treatment: a retrospective analysis.
    Acta diabetologica, 2014, Volume: 51, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder;

2014
Recurrent brief depressive disorder in Dhat syndrome: A biological or psychological phenomenon!
    The Australian and New Zealand journal of psychiatry, 2016, Volume: 50, Issue:3

    Topics: Adult; Clomipramine; Cognitive Behavioral Therapy; Depressive Disorder; Fluoxetine; Humans; Male; Ob

2016
Effect of neonatal clomipramine in the pathogenesis of ligature-induced periodontitis in Lewis rats.
    Acta odontologica Scandinavica, 2009, Volume: 67, Issue:2

    Topics: Alveolar Bone Loss; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; C

2009
Effects of postnatal isolation rearing and antidepressant treatment on the density of serotonergic and noradrenergic axons and depressive behavior in rats.
    Neuroscience, 2009, Sep-29, Volume: 163, Issue:1

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Antidepressive Agents; Antidepressive Agents, Tricycl

2009
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
    Neuropharmacology, 2010, Volume: 58, Issue:7

    Topics: Anabolic Agents; Androgens; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brai

2010
Gene expression patterns in a rodent model for depression.
    The European journal of neuroscience, 2010, Volume: 31, Issue:8

    Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Female; Gene Expression; Male; O

2010
Prolactin and cortisol responses to acute intravenous clomipramine challenge in patients with mania, depression and healthy controls: evidence for reduced serotonergic responsivity.
    Neuropsychobiology, 2011, Volume: 63, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Bipolar Disorder; Brain; Clomipramine; Depressive Disorder; Femal

2011
Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample.
    Pharmacogenomics, 2011, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP B

2011
Therapeutic drug monitoring of clomipramine and amitriptyline in a depressed patient with upper digestive tract resection.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Drug Monitoring;

2011
Clomipramine concentration and withdrawal symptoms in 10 neonates.
    British journal of clinical pharmacology, 2012, Volume: 73, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Half-Life; Human

2012
Sleep-related epilepsy in a Long-Evans hooded rat model of depression.
    Sleep & breathing = Schlaf & Atmung, 2012, Volume: 16, Issue:4

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dise

2012
Sleep homeostasis and depression: studies with the rat clomipramine model of depression.
    Neuroscience, 2012, Jun-14, Volume: 212

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depress

2012
Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression.
    Journal of proteome research, 2012, Dec-07, Volume: 11, Issue:12

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Body

2012
The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders.
    Stress (Amsterdam, Netherlands), 2002, Volume: 5, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Disease Models, Animal

2002
Sleep-wake effects of yohimbine and atropine in rats with a clomipramine-based model of depression.
    Neuroreport, 2002, Sep-16, Volume: 13, Issue:13

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Aggression; Animals; Animals, Newborn; Antidepressive Agen

2002
Role of Gi proteins in the antidepressant-like effect of amitriptyline and clomipramine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Brain Chemistry; Clomipramine; Depr

2002
Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral 'despair' in a mouse model of depression.
    Neuroscience, 2002, Volume: 115, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Dise

2002
Differential effects of the 5-HT2 receptor antagonist on the anti-immobility effects of noradrenaline and serotonin reuptake inhibitors in the forced swimming test.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Brain; Clomipramine; Depressive Disorder; Dose-Response Relat

2002
Alterations in voiding frequency and cystometry in the clomipramine induced model of endogenous depression and reversal with fluoxetine.
    The Journal of urology, 2003, Volume: 170, Issue:5

    Topics: Animals; Antidepressive Agents, Second-Generation; Clomipramine; Depressive Disorder; Escape Reactio

2003
[Olanzapine in therapy of a somatoform disorder].
    Psychiatrische Praxis, 2003, Volume: 30, Issue:8

    Topics: Antipsychotic Agents; Benzodiazepines; Chest Pain; Clomipramine; Depressive Disorder; Dose-Response

2003
Antidepressants blunt the effects of inescapable stress on male mating behaviour and decrease corticotropin-releasing hormone mRNA expression in the hypothalamic paraventricular nucleus of the Syrian hamster (Mesocricetus auratus).
    Journal of neuroendocrinology, 2004, Volume: 16, Issue:7

    Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clomipramine; Corticotropin-Releasing

2004
Two cases involving clomipramine intoxication.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Biotransformation; Chromatography, Gas; Clomipramine; Depre

2004
[Paroxetine versus clomipramine in female adolescents suffering from anorexia nervosa and depressive episode--a retrospective study on tolerability, reasons for discontinuing the antidepressive treatment and different outcome measurements].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2004, Volume: 32, Issue:4

    Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy

2004
Antidepressant effects of nicotine and fluoxetine in an animal model of depression induced by neonatal treatment with clomipramine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepr

2005
Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Affect; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Antipsychotic

2007
A kinetic-pharmacodynamic model for clinical trial simulation of antidepressant action: application to clomipramine-lithium interaction.
    Contemporary clinical trials, 2007, Volume: 28, Issue:3

    Topics: Antidepressive Agents; Clomipramine; Data Interpretation, Statistical; Depressive Disorder; Double-B

2007
Increased sensitivity to antidepressants of D3 dopamine receptor-deficient mice in the forced swim test (FST).
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:4

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri

2008
Neonatal clomipramine induced endogenous depression in rats is associated with learning impairment in adulthood.
    Behavioural brain research, 2008, Feb-11, Volume: 187, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Fema

2008
Therapeutic drug monitoring of tricyclic antidepressants in everyday clinical practice.
    Journal of neural transmission. Supplementum, 2007, Issue:72

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive D

2007
Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus.
    Behavioural brain research, 2008, Mar-17, Volume: 188, Issue:1

    Topics: Animals; Antidepressive Agents; Chronic Disease; Clomipramine; Depressive Disorder; Disease Models,

2008
[Efficacy and tolerability of clomipramine, pirlindole and escitalopram in the treatment of neurotic level depression].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive A

2008
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Benzamide

2008
Beta-adrenergic stimulation and antidepressant activity.
    Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine;

1981
[Management of treatment-resistant depression without ECT (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, May-22, Volume: 106, Issue:21

    Topics: Antipsychotic Agents; Clomipramine; Depressive Disorder; Female; Humans; Male; Maprotiline; Nomifens

1981
[Treatment of endogenous depressions with maprotiline, clomipramine, dibenzepine and pyrlindole (author's transl)].
    Ceskoslovenska psychiatrie, 1981, Volume: 77, Issue:3

    Topics: Adult; Antidepressive Agents; Carbazoles; Clomipramine; Depressive Disorder; Dibenzazepines; Female;

1981
[Treatment of therapy-refractory depressions].
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Anthracenes; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Depressive Disorder; Drug Th

1982
Urinary excretion of 5-hydroxyindoleacetic acid--no relationship to the level in cerebrospinal fluid.
    Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:3

    Topics: Clomipramine; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Suicide, Attempted

1982
Relevance of plasma levels during clomipramine treatment of primary depression.
    Journal of affective disorders, 1982, Volume: 4, Issue:2

    Topics: Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Kinetics

1982
Distal colon motility as a predictor of antidepressant response to fenfluramine, imipramine and clomipramine.
    Journal of affective disorders, 1983, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Clomipramine; Colon; Depressive Disorder; Double-Blind Method; Female; Fenflurami

1983
Classification of depression and response to antidepressive therapies.
    The British journal of psychiatry : the journal of mental science, 1983, Volume: 143

    Topics: Amitriptyline; Clomipramine; Combined Modality Therapy; Depressive Disorder; Electroconvulsive Thera

1983
Plasma levels and clinical response during treatment with clomipramine.
    Journal of affective disorders, 1984, Volume: 6, Issue:1

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Time Factors

1984
[Radioimmunoassay of clomipramine and amitriptyline. Monitoring plasma levels of clomipramine in endogenous depression].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Feb-03, Volume: 59, Issue:5

    Topics: Amitriptyline; Clomipramine; Depressive Disorder; Humans; Radioimmunoassay

1983
The TSH-response to TRH: A possible predictor of outcome to antidepressant and neuroleptic treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:2-3

    Topics: Adolescent; Adult; Aged; Clomipramine; Depressive Disorder; Female; Haloperidol; Humans; Middle Aged

1983
TSH-response patterns to TRH stimulation may indicate therapeutic mechanisms of antidepressant and neuroleptic drugs.
    Neuropsychobiology, 1984, Volume: 11, Issue:4

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Haloperidol; Humans; Prognosis; Psychiatric Status

1984
5-HT reuptake inhibitors plus tryptophan in endogenous depression.
    Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290

    Topics: Biogenic Amines; Brompheniramine; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Thera

1981
Relevance of tryptophan and tyrosine availability in endogenous and 'non-endogenous' depressives treated with imipramine or clomipramine.
    Journal of affective disorders, 1981, Volume: 3, Issue:3

    Topics: Biological Availability; Clomipramine; Depression; Depressive Disorder; Humans; Imipramine; Time Fac

1981
Effects of clomipramine infusion on sleep in depressed patients.
    Neuropsychobiology, 1984, Volume: 11, Issue:2

    Topics: Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Electroencephalography; Female; Humans;

1984
[When do I give which antidepressant in the individual case?].
    Der Nervenarzt, 1984, Volume: 55, Issue:9

    Topics: Anthracenes; Antidepressive Agents; Clomipramine; Depressive Disorder; Humans; Maprotiline; Monoamin

1984
Biological markers in obsessive-compulsive and affective disorders.
    Journal of psychiatric research, 1984, Volume: 18, Issue:4

    Topics: Blood Platelets; Clomipramine; Clonidine; Depressive Disorder; Dexamethasone; Electroencephalography

1984
Serial application of clonidine tests during antidepressive treatment with chlorimipramine.
    Pharmacopsychiatry, 1984, Volume: 17, Issue:6

    Topics: Adult; Clomipramine; Clonidine; Depressive Disorder; Drug Therapy, Combination; Female; Growth Hormo

1984
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
    Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomip

1984
Cardiac effects of clomipramine treatment. ECG and left ventricular systolic time intervals.
    Neuropsychobiology, 1983, Volume: 9, Issue:2-3

    Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathies; Clomipramine; Depressive Disorder; Ele

1983
Effect of sleep deprivation as a predictor of treatment response to antidepressant medication.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:5

    Topics: Adult; Aged; Anthracenes; Clomipramine; Depressive Disorder; Female; Humans; Male; Maprotiline; Midd

1983
Unusual side effects of clomipramine associated with yawning.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:7

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Male; Orgasm; Respiration

1983
[Activation motor response in depressive states. Changes in the Hoffmann reflex during psychomotor testing].
    L'Encephale, 1983, Volume: 9, Issue:3

    Topics: Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Heart Rate; Humans; Middle Aged; Reflex,

1983
Clinical and biological parameters as predictors for antidepressant drug responses in depressed patients.
    Pharmacopsychiatria, 1983, Volume: 16, Issue:6

    Topics: Adult; Aged; Anthracenes; Catechol O-Methyltransferase; Clomipramine; Depressive Disorder; Dopamine

1983
[Report of experiences with high dosage Hydiphen infusion treatment of depressive syndromes].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1984, Volume: 36, Issue:2

    Topics: Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Female

1984
Neonatal convulsions caused by withdrawal from maternal clomipramine.
    British medical journal (Clinical research ed.), 1982, Jun-19, Volume: 284, Issue:6332

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases

1982
[Our first experience with the antidepressive Hydiphen (clomipramine)].
    Ceskoslovenska psychiatrie, 1983, Volume: 79, Issue:1

    Topics: Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged

1983
Antidepressant drugs in the treatment of obsessive-compulsive disorders.
    Journal of behavior therapy and experimental psychiatry, 1983, Volume: 14, Issue:1

    Topics: Clomipramine; Depressive Disorder; Humans; Obsessive-Compulsive Disorder; Social Adjustment

1983
Monoamine oxidase activity in platelets before and after sleep deprivation as predictor for antidepressive drug response.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: Antidepressive Agents; Blood Platelets; Clomipramine; Depressive Disorder; Female; Humans; Kinetics;

1983
Double-blind trial with oral versus intravenous clomipramine in primary depression.
    Biological psychiatry, 1983, Volume: 18, Issue:6

    Topics: Administration, Oral; Clomipramine; Depressive Disorder; Double-Blind Method; Humans; Injections, In

1983
[Plasma levels of desmethylclomipramine and clomipramine at steady-state in the morning. Correlative analysis and prediction of theoretical blood clomipramine].
    L'Encephale, 1983, Volume: 9, Issue:1

    Topics: Adult; Aged; Circadian Rhythm; Clomipramine; Depressive Disorder; Female; Humans; Hydrocortisone; Ma

1983
[Comparison of the onset of the therapeutic effect of clomipramine and desipramine after oral and intravenous administration in patients with endogenous depression].
    Ceskoslovenska psychiatrie, 1983, Volume: 79, Issue:3

    Topics: Administration, Oral; Clomipramine; Depressive Disorder; Desipramine; Humans; Infusions, Parenteral

1983
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
    Psychiatry research, 1981, Volume: 4, Issue:2

    Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans;

1981
Pharmacokinetics of clomipramine in depressive patients.
    Psychiatry research, 1981, Volume: 4, Issue:2

    Topics: Administration, Oral; Adult; Clomipramine; Depressive Disorder; Female; Humans; Injections, Intramus

1981
Neonatal effects of maternal clomipramine treatment.
    Pediatrics, 1982, Volume: 69, Issue:2

    Topics: Acidosis, Respiratory; Clomipramine; Cyanosis; Depressive Disorder; Female; Humans; Infant, Newborn;

1982
On the clinical response/plasma level relationship for clomipramine.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Clomipramine; Depressive Disorder; Humans

1982
Sexual disorders in the course of clomipramine treatment: a report of three cases.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1982, Volume: 27, Issue:2

    Topics: Bipolar Disorder; Clomipramine; Depressive Disorder; Erectile Dysfunction; Humans; Male; Middle Aged

1982
Neuroendocrine mechanisms in the therapeutic effects of antidepressant drugs: the "thyroid-axis" hypothesis.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Antidepressive Agents; Clomipramine; Depressive Disorder; Female; Humans; Psychiatric Status Rating

1982
Clinical experience with maprotilin and maprotilin/clomipramine infusions in resistant depression.
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Administration, Oral; Adult; Anthracenes; Clomipramine; Depressive Disorder; Drug Therapy, Combinati

1982
[Combined chlorimipramine and maprotiline therapy in therapy-resistant depressions].
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Adult; Anthracenes; Bipolar Disorder; Clomipramine; Depressive Disorder; Drug Therapy, Combination;

1982
[Plasma level monitoring of psychotropic drugs in children. II -- Antidepressants (author's transl)].
    La Nouvelle presse medicale, 1982, Jun-26, Volume: 11, Issue:30

    Topics: Adolescent; Antidepressive Agents; Child; Clomipramine; Depressive Disorder; Enuresis; Female; Human

1982
[Treatment of therapy-resistant depressions. Results of combined infusion treatment].
    Schweizerische medizinische Wochenschrift, 1982, Aug-03, Volume: 112, Issue:31-32

    Topics: Anthracenes; Clomipramine; Depressive Disorder; Female; Humans; Infusions, Parenteral; Male; Maproti

1982
Phospholipid liposomes in depression: a double-blind study versus placebo.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:4

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Synergism; Female; Humans;

1982
Sexual dysfunction and clomipramine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1982, Volume: 27, Issue:3

    Topics: Adult; Clomipramine; Depressive Disorder; Drug Administration Schedule; Ejaculation; Erectile Dysfun

1982
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
    Der Nervenarzt, 1980, Volume: 51, Issue:12

    Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans;

1980
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethaso

1981
[Clinical investigation comparing trazodone and clomipramine].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1980, Volume: 32, Issue:12

    Topics: Clomipramine; Depressive Disorder; Humans; Piperazines; Trazodone

1980
[The problem of side-effects: cardiotoxicity (author's transl)].
    L'Encephale, 1981, Volume: 7, Issue:4 Suppl

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dibenzocyclohept

1981
[Clomipramine and desmethylclomipramine: relationship between plasma levels and clinical effect (author's transl)].
    L'Encephale, 1981, Volume: 7, Issue:5

    Topics: Adjustment Disorders; Adult; Aged; Clomipramine; Depressive Disorder; Female; Humans; Kinetics; Male

1981
Uptake of 5-hydroxytryptamine and dopamine into platelets from depressed patients and normal subjects--influence of clomipramine, desmethylclomipramine and maprotiline.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 1

    Topics: Adjustment Disorders; Adult; Aged; Antidepressive Agents, Tricyclic; Blood Platelets; Clomipramine;

1980
The WHO Depression Scale. Relationship to the Newcastle Scales.
    Acta psychiatrica Scandinavica, 1980, Volume: 62, Issue:2

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Im

1980
Extreme suicidality following serotonin syndrome.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 167, Issue:3

    Topics: Adolescent; Antidepressive Agents; Clomipramine; Depressive Disorder; Dothiepin; Drug Administration

1995
[Personality disorders and obsessive-compulsive disorder: critical analysis of the literature data and our studies].
    Minerva psichiatrica, 1995, Volume: 36, Issue:1

    Topics: Clomipramine; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Obsessive-Compulsive Disorder; P

1995
Acute vs. chronic EEG effects in maprotiline- and in clomipramine-treated depressive inpatients and the prediction of therapeutic outcome.
    Journal of affective disorders, 1994, Volume: 32, Issue:3

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalogr

1994
Combined pharmacotherapy: an emerging trend in pediatric psychopharmacology.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:1

    Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Child Psychiatry;

1995
Possible serotonin syndrome following the combined administration of clomipramine and alprazolam.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:3

    Topics: Aged; Alprazolam; Clomipramine; Depressive Disorder; Female; Humans; Serotonin; Syndrome

1995
[A case of rare side effects of certain antidepressive drugs].
    Der Nervenarzt, 1995, Volume: 66, Issue:1

    Topics: Adult; Antidepressive Agents; Clomipramine; Depressive Disorder; Diagnosis, Differential; Drug Thera

1995
Three cases of alopecia areata induced by zotepine.
    Acta neurologica, 1993, Volume: 15, Issue:3

    Topics: Adult; Alopecia; Alopecia Areata; Antipsychotic Agents; Autoimmune Diseases; Carbamazepine; Clomipra

1993
Figure drawing and psychomotor retardation: preliminary report.
    Journal of affective disorders, 1993, Volume: 29, Issue:4

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Clomipramine; Depressive Disorder; Female; Humans; Male;

1993
The effects of a 3-day increase of ambient temperature on body temperature and REM sleep in an animal model of depression.
    Sleep, 1994, Volume: 17, Issue:4

    Topics: Acclimatization; Animals; Animals, Newborn; Body Temperature Regulation; Circadian Rhythm; Clomipram

1994
Clomipramine therapy in the geriatric hospital: experience with therapeutic drug monitoring.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Clomipramine; Comorbidity; Depressive Disorder; Drug Interactions; D

1994
Determination of 5-hydroxytryptamine and tryptophan by liquid chromatography in whole blood. Its interest for the exploration of mental disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Benzamides; Chromatography, High Pressure Liquid; Clomipram

1994
Clinical significance of plasma levels of clomipramine, its hydroxylated and desmethylated metabolites: prediction of clinical outcome in mood disorders using discriminant analysis of therapeutic drug monitoring data.
    Journal of affective disorders, 1993, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Biotransformation; Bipolar Disorder; Clomipramine; Depressive Disorder; Dru

1993
Concurrent agranulocytosis and hepatitis secondary to clomipramine therapy.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 162

    Topics: Aged; Agranulocytosis; Chemical and Drug Induced Liver Injury; Clomipramine; Depressive Disorder; Hu

1993
[Scurvy after a suicide attempt by starvation].
    Deutsche medizinische Wochenschrift (1946), 1994, Apr-22, Volume: 119, Issue:16

    Topics: Adult; Ascorbic Acid; Clomipramine; Depressive Disorder; Erythrocyte Count; Erythrocyte Indices; Hem

1994
Cytokine production in major depressed patients before and after clomipramine treatment.
    Biological psychiatry, 1994, Jan-01, Volume: 35, Issue:1

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Female; Humans; Interleukin-1; Interleukin-2; Interl

1994
Serotonin syndrome during clomipramine and lithium treatment.
    The American journal of psychiatry, 1993, Volume: 150, Issue:12

    Topics: Clomipramine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Humans; Lithium; Ma

1993
The central nervous system serotonin syndrome.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:1

    Topics: Adult; Central Nervous System; Clomipramine; Depressive Disorder; Dextromethorphan; Drug Interaction

1993
Comorbid anxious signs and symptoms in major depression: impact on functional work capacity and comparative treatment outcomes.
    International clinical psychopharmacology, 1993,Winter, Volume: 8, Issue:4

    Topics: Absenteeism; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Clomipramine; Comorbid

1993
Plasma-free and sulfoconjugated MHPG in major depressive disorders: differences between responders to treatment and nonresponders.
    Biological psychiatry, 1993, Nov-01, Volume: 34, Issue:9

    Topics: Adolescent; Adult; Aged; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Female

1993
Sexual dysfunction during antidepressant treatment.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:6

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder;

1993
Decreased raphe unit activity in a rat model of endogenous depression.
    Brain research, 1993, May-14, Volume: 611, Issue:1

    Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Electric Stimulation; Evoked Pot

1993
Body dysmorphic disorder: 30 cases of imagined ugliness.
    The American journal of psychiatry, 1993, Volume: 150, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Agoraphobia; Anxiety Disorders; Body Image; Clomipramine; Delu

1993
[Infusion therapy with antidepressants in patients with depression].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1993, Feb-23, Volume: 82, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Clomipramine; Depressive Disorder; Female; Follow-Up Studies; Humans

1993
[Panic attacks and panic disorders in the child].
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:1

    Topics: Anxiety, Separation; Child; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Dru

1993
The benefits of clomipramine-fluoxetine combination in obsessive compulsive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:4

    Topics: Adult; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

1993
Clomipramine efficacy for Tourette syndrome and major depression: a case study.
    Biological psychiatry, 1995, Sep-15, Volume: 38, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Tourette

1995
Quality of life in depressed patients: comparison of fluoxetine and major tricyclic antidepressants.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:1

    Topics: Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Clomipramine; Depressi

1996
Pharmacokinetic fluvoxamine-clomipramine interaction with favorable therapeutic consequences in therapy-resistant depressive patient.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Combined M

1996
Depression as a dynamical disease.
    Biological psychiatry, 1996, Jun-15, Volume: 39, Issue:12

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Arousal; Brain; C

1996
Rapid synergistic effects of lithium and antidepressants.
    Psychopharmacology, 1995, Volume: 122, Issue:2

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Clomipramine; Depressive Dis

1995
Metabolic interaction between fluoxetine and clomipramine: a case report.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic;

1996
Status epilepticus associated with the combination of valproic acid and clomipramine.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:1

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female;

1997
Syndrome of inappropriate antidiuretic hormone (SIADH) in an 80-year-old woman given clomipramine.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1997,Summer, Volume: 5, Issue:3

    Topics: Aged; Aged, 80 and over; Clomipramine; Delirium; Depressive Disorder; Diagnosis, Differential; Dose-

1997
Three years on clomipramine: before and after brain SPECT study.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1997, Volume: 9, Issue:2

    Topics: Anger; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Brain; Clomi

1997
Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment.
    Biological psychiatry, 1997, Oct-15, Volume: 42, Issue:8

    Topics: Adult; Antidepressive Agents; Blood Platelets; Citalopram; Clomipramine; Depressive Disorder; Dose-R

1997
Olfactory reference syndrome responds to clomipramine but not fluoxetine: a case report.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:11

    Topics: Adult; Clomipramine; Comorbidity; Delusions; Depressive Disorder; Fluoxetine; Humans; Male; Obsessiv

1997
[The management of Sandra G].
    Soins. Psychiatrie, 1997, Issue:192

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Diagnosis, Differential; Humans

1997
Muscle dysmorphia.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:8

    Topics: Adult; Body Constitution; Clomipramine; Depressive Disorder; Exercise; Humans; Male; Psychiatric Sta

1997
Serotonin syndrome--clomipramine too soon after moclobemide?
    International clinical psychopharmacology, 1997, Volume: 12, Issue:6

    Topics: Adult; Benzamides; Central Nervous System Diseases; Clomipramine; Depressive Disorder; Drug Interact

1997
When fluvoxamine treats only depression and clomipramine treats only obsessive-compulsive disorder--combine them?
    The Journal of neuropsychiatry and clinical neurosciences, 1998,Winter, Volume: 10, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Attention Deficit

1998
Ultrarapid metabolism of clomipramine in a therapy-resistant depressive patient, as confirmed by CYP2 D6 genotyping.
    Pharmacopsychiatry, 1998, Volume: 31, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Cytochrome P-450 CYP2D6; Depressive Disorder; Genoty

1998
Relationship between blood serotonergic variables, melancholic traits, and response to antidepressant treatments.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:3

    Topics: Adult; Antidepressive Agents; Blood Platelets; Clomipramine; Depressive Disorder; Depressive Disorde

1998
Pulse clomipramine for depressed adolescents.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Adolescent; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Humans; Placebos; Randomize

1998
[The hyperglycemic dehydration syndrome].
    Nederlands tijdschrift voor geneeskunde, 1998, Oct-10, Volume: 142, Issue:41

    Topics: Adult; Antidepressive Agents; Benzodiazepines; Clomipramine; Dehydration; Depressive Disorder; Diabe

1998
[Hematological changes and antidepressive treatment].
    Atencion primaria, 1999, Feb-28, Volume: 23, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Leukopen

1999
Fluoxetine for clomipramine withdrawal symptoms.
    The American journal of psychiatry, 1999, Volume: 156, Issue:4

    Topics: Adult; Clomipramine; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Male; Panic Disorder; Sub

1999
A puzzling case of seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration.
    Acta psychiatrica Scandinavica, 1999, Volume: 99, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Hallucinations; Humans;

1999
[Proofs of efficacy].
    L'Encephale, 1999, Volume: 25 Spec No 2

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanols; Depressive Disorder; Dose-Response Re

1999
Successful antidepressant treatment for five terminally ill cancer patients with major depression, suicidal ideation and a desire for death.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:6

    Topics: Affect; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Attitude to Death; Clomipramine; Cogn

1999
Decreased platelet serotonin transporter sites and increased platelet inositol triphosphate levels in patients with unipolar depression: effects of clomipramine and fluoxetine.
    Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Blood Platelets;

1999
Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants.
    Neurogastroenterology and motility, 2000, Volume: 12, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Cathartics; Cholinergic Antagonists;

2000
Delirious episodes induced by intravenous administration of clomipramine associated with an acute increase in its plasma concentrations.
    Psychiatry and clinical neurosciences, 2000, Volume: 54, Issue:6

    Topics: Aged; Clomipramine; Delirium; Depressive Disorder; Female; Humans; Injections, Intravenous; Middle A

2000
Lithium therapy for corticosteroid-induced mood disorder.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:1

    Topics: Acute Disease; Adrenal Cortex Hormones; Antidepressive Agents, Tricyclic; Clomipramine; Comorbidity;

2001
[Chronic discomfort with dentures - successful treatment with clomipramine].
    Psychiatrische Praxis, 2001, Volume: 28, Issue:6

    Topics: Aged; Antidepressive Agents, Tricyclic; Clomipramine; Dental Restoration Failure; Dentures; Depressi

2001
The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Alleles; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hy

2001
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2001, Volume: 11, Issue:66

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autopsy; Binding Sites; Brain; Clomipramine; Depres

2001
Neuroendocrine effects of intravenous clomipramine in depressed patients and healthy subjects.
    The American journal of psychiatry, 1992, Volume: 149, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Clomipramine; Depressive Disorder; Female; Hospitali

1992
[Changes in somatosensory evoked potentials in pharmacogenic myoclonia].
    Der Nervenarzt, 1992, Volume: 63, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Depressive Disor

1992
Carbamazepine addition in tricyclic antidepressant-resistant unipolar depression.
    Biological psychiatry, 1992, Aug-15, Volume: 32, Issue:4

    Topics: Aged; Anxiety Disorders; Carbamazepine; Clomipramine; Depressive Disorder; Dose-Response Relationshi

1992
[Neonatal withdrawal symptoms following the use of clomipramine during pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1992, Jul-25, Volume: 136, Issue:30

    Topics: Adult; Clomipramine; Clonazepam; Depressive Disorder; Female; Humans; Infant, Newborn; Male; Neonata

1992
Tricyclic antidepressant plasma levels after fluoxetine addition.
    Neuropsychobiology, 1992, Volume: 25, Issue:4

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dos

1992
Clomipramine plasma levels among depressed outpatients in Benin, west Africa: drug compliance and comparison with Caucasian patients.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Ambulatory Care; Benin; Black People; Clomipramine; Depressive Disorder; Humans; Patient Compliance;

1992
Neonatal treatment with clomipramine increased immobility in the forced swim test: an attribute of animal models of depression.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Animals; Animals, Newborn; Clomipramine; Defecation; Depressive Disorder; Disease Models, Animal; Ma

1992
The serotonin syndrome.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Adult; Clomipramine; Depressive Disorder; Humans; Male; Myoclonus; Serotonin; Syndrome

1992
Can non-REM sleep be depressogenic?
    Journal of affective disorders, 1992, Volume: 24, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipramine; Depressive Disorder; Electroencepha

1992
Decreased 5-HT-mediated prolactin release in major depression.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Adult; Brain; Clomipramine; Depressive Disorder; Female; Humans; Infusions, Intravenous; Male; Perso

1992
[A control study of intravenous versus oral clomipramine in major depression].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Clomipramine; Depressive Disorder; Female; Humans; Injectio

1992
Circadian temperature and sleep-wake rhythms in depression.
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:1

    Topics: Adult; Body Temperature Regulation; Circadian Rhythm; Clomipramine; Depressive Disorder; Female; Hum

1992
Effects of clomipramine treatment on cerebrospinal fluid monoamine metabolites and platelet 3H-imipramine binding and serotonin uptake and concentration in major depressive disorder.
    Acta psychiatrica Scandinavica, 1991, Volume: 83, Issue:2

    Topics: Adult; Blood Platelets; Carrier Proteins; Clomipramine; Depressive Disorder; Female; Homovanillic Ac

1991
Memory effects of clomipramine treatment: relationship to CSF monoamine metabolites and drug concentrations in plasma.
    Biological psychiatry, 1991, Dec-01, Volume: 30, Issue:11

    Topics: Adult; Aged; Attention; Brain; Clomipramine; Depressive Disorder; Female; Homovanillic Acid; Humans;

1991
Painful ejaculation associated with antidepressants in four patients.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:11

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Ejaculation; Humans; Imi

1991
Toxic neonatal effects following maternal clomipramine therapy.
    Journal of toxicology. Clinical toxicology, 1991, Volume: 29, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Animals; Bottle Feeding; Breast Feeding; Clomipramine; Depressive Di

1991
[ICU syndrome].
    Kokyu to junkan. Respiration & circulation, 1991, Volume: 39, Issue:12

    Topics: Aged; Anxiety; Benzodiazepines; Clomipramine; Critical Care; Delirium; Depressive Disorder; Female;

1991
Musical hallucinations triggered by clomipramine?
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Aged; Agoraphobia; Clomipramine; Depressive Disorder; Female; Hallucinations; Humans; Music

1991
Fluoxetine treatment of obsessive-compulsive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1991, Volume: 36, Issue:10

    Topics: Adult; Arousal; Clomipramine; Combined Modality Therapy; Depressive Disorder; Drive; Female; Fluoxet

1991
Prediction of efficacy of antidepressant by 1-week test therapy in depression.
    Journal of affective disorders, 1991, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Dexamethasone; Dose-Response

1991
Interhemispheric serotonergic asymmetry reflected in topographic pharmaco-EEG.
    Psychiatry research, 1991, Volume: 40, Issue:1

    Topics: Brain Mapping; Cerebral Cortex; Clomipramine; Depressive Disorder; Dominance, Cerebral; Electroencep

1991
The obsessive quality and clomipramine treatment in PTSD.
    The American journal of psychiatry, 1991, Volume: 148, Issue:8

    Topics: Clomipramine; Depressive Disorder; Hospitalization; Humans; Life Change Events; Psychiatric Status R

1991
Trichotillomania and depression.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:1

    Topics: Adolescent; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Humans

1991
Neurologic soft signs in obsessive-compulsive disorder.
    Archives of general psychiatry, 1991, Volume: 48, Issue:3

    Topics: Adult; Anxiety Disorders; Central Nervous System Diseases; Clomipramine; Clonidine; Depressive Disor

1991
Immediate effects of intravenous clomipramine on sleep and sleep-related secretion in depressed patients.
    Psychiatry research, 1991, Volume: 36, Issue:3

    Topics: Adult; Arousal; Clomipramine; Delta Rhythm; Depressive Disorder; Electroencephalography; Female; Gro

1991
Abnormal neuroendocrine responsivity to acute i.v. clomipramine challenge in depressed patients.
    Psychiatry research, 1990, Volume: 31, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Brain; Clomipramine; Depressive Disorder; Female; Growth Hormone

1990
Why some depressed patients may have low platelet 3H-imipramine binding.
    Acta psychiatrica Scandinavica, 1990, Volume: 82, Issue:4

    Topics: Antidepressive Agents; Blood Platelets; Carrier Proteins; Cell Membrane; Clomipramine; Depressive Di

1990
Predictive value of two endogenicity measures.
    Psychopathology, 1990, Volume: 23, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder; Female; Hostility; Humans; Ma

1990
Treatment of clomipramine-induced anorgasmia with yohimbine: a case report.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:1

    Topics: Adult; Clomipramine; Depressive Disorder; Humans; Male; Obsessive-Compulsive Disorder; Orgasm; Place

1990
The treatment of monodelusional psychosis associated with depression.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Clomipramine; Delusions; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combin

1990
Childhood obsessive-compulsive disorder: a prospective follow-up study.
    Journal of child psychology and psychiatry, and allied disciplines, 1990, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Anxiety Disorders; Child; Clomipramine; Depressive Disorder; Dexamethasone; Femal

1990
Procedure- and age-dependent hyperactivity in a new animal model of endogenous depression.
    Neuroscience and biobehavioral reviews, 1990,Spring, Volume: 14, Issue:1

    Topics: Aging; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Disease Models, Animal; Hy

1990
Diminished sexual activity in a new animal model of endogenous depression.
    Neuroscience and biobehavioral reviews, 1990,Spring, Volume: 14, Issue:1

    Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Rats; Rats, Inbred Strains; Sexu

1990
REM sleep abnormalities in a new animal model of endogenous depression.
    Neuroscience and biobehavioral reviews, 1990,Spring, Volume: 14, Issue:1

    Topics: Animals; Clomipramine; Depressive Disorder; Disease Models, Animal; Male; Rats; Rats, Inbred Strains

1990
The effects of total sleep deprivation and subsequent treatment with clomipramine on depressive symptoms and sleep electroencephalography in patients with a major depressive disorder.
    Acta psychiatrica Scandinavica, 1990, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Clomipramine; Depressive Disorder; Electroencephalography; Female; Humans; Male;

1990
"Anger attacks": possible variants of panic and major depressive disorders.
    The American journal of psychiatry, 1990, Volume: 147, Issue:7

    Topics: Adult; Anger; Anxiety Disorders; Clomipramine; Clonazepam; Depressive Disorder; Desipramine; Diagnos

1990
Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan.
    Klinische Wochenschrift, 1990, Jul-17, Volume: 68, Issue:14

    Topics: Adult; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Eosinophilia; Female; Humans; L

1990
Clomipramine metabolism. Model-based analysis of variability factors from drug monitoring data.
    Clinical pharmacokinetics, 1990, Volume: 19, Issue:3

    Topics: Adult; Aged; Aging; Biotransformation; Chromatography, High Pressure Liquid; Clomipramine; Dealkylat

1990
Rebound antidepressant cardiac arrhythmia.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Cardiac Complexes, Premature; Clomipramine; Depressive Disorder; Electrocardiography; Female; Humans

1988
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Respo

1989
Panic attacks and major depression after discontinuation of long-term diazepam abuse.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:12

    Topics: Adult; Anxiety; Clomipramine; Depressive Disorder; Diazepam; Fear; Female; Humans; Panic; Substance

1989
Intravenous chlorimipramine therapy in obsessive-compulsive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1989, Volume: 34, Issue:9

    Topics: Administration, Oral; Adult; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Fo

1989
Subjective bias in reports of poor work adjustment in depressed patients.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:6

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Follow-Up Studies; Humans; Job Satisfaction; Male;

1989
[Introduction of chronopharmacologic therapy of depressive disorders--a double-blind study using clomipramine].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1989, Volume: 91, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Chronobiology Phenomena; Clomipramine; Depressive Disorder;

1989
Jerk-locked averaging and somatosensory evoked potential in tricyclic-induced myoclonus: a case report.
    The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:4

    Topics: Adult; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalography;

1989
Observed behavior as a predictor of the response to sleep deprivation in depressed patients.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Adult; Arousal; Attention; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Mot

1989
High blood concentrations of imipramine or clomipramine and therapeutic failure: a case report study using drug monitoring data.
    Therapeutic drug monitoring, 1989, Volume: 11, Issue:4

    Topics: Aged; Clomipramine; Debrisoquin; Depressive Disorder; Female; Humans; Hydroxylation; Imipramine; Mid

1989
Intravenous pulse loading of clomipramine in adolescents with depression.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:1

    Topics: Adolescent; Clomipramine; Depressive Disorder; Female; Humans; Male; Psychiatric Status Rating Scale

1989
New findings in anxiety. A synthesis for clinical practice in 1985.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Anxiety Disorders; Behavior Therapy;

1985
Is the dexamethasone suppression test predictive of response to specific antidepressant treatment in major depression?
    Acta psychiatrica Scandinavica, 1987, Volume: 76, Issue:2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Depressive Disord

1987
Enhanced binding of [3H] (-) adrenaline to platelets of depressed patients with melancholia: effect of long-term clomipramine treatment.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:2

    Topics: Adult; Aged; Blood Platelets; Clomipramine; Depressive Disorder; Epinephrine; Female; Humans; Kineti

1987
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Cl

1987
[Rapid response of a disorder to the addition of lithium carbonate: panic resistant to tricyclic antidepressants].
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:4

    Topics: Adult; Amitriptyline; Anxiety Disorders; Clomipramine; Depressive Disorder; Drug Therapy, Combinatio

1986
Prolactin in patients with major depressive disorder and in healthy subjects. II. Longitudinal study of basal prolactin and post-TRH-stimulated prolactin levels.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Adult; Aged; Clomipramine; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Longi

1988
Lithium augmentation of clomipramine.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:11

    Topics: Adult; Anxiety Disorders; Clomipramine; Depressive Disorder; Drug Synergism; Drug Therapy, Combinati

1988
Body core temperature and depression during total sleep deprivation in depressives.
    Biological psychiatry, 1988, Volume: 24, Issue:5

    Topics: Body Temperature Regulation; Circadian Rhythm; Clomipramine; Combined Modality Therapy; Depressive D

1988
Thrombosis of cerebral veins following intravenous application of clomipramine.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:11

    Topics: Cerebral Veins; Clomipramine; Depressive Disorder; Female; Humans; Infusions, Intravenous; Intracran

1988
EEG characteristics of clinically defined on-drug-responders and non-responders--a comparison clomipramine vs. maprotiline.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Adult; Aged; Anthracenes; Clomipramine; Depressive Disorder; Electroencephalography; Female; Humans;

1988
[Adverse drug reactions in combined treatment with tricyclic antidepressants and monoamine oxidase inhibitors].
    Der Nervenarzt, 1988, Volume: 59, Issue:2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dru

1988
Clomipramine by different routes of administration: short- and long-term efficacy and predictors of clinical outcome.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:3

    Topics: Clomipramine; Depressive Disorder; Humans; Time Factors

1987
Clomipramine-induced pancytopenia.
    The Journal of nervous and mental disease, 1987, Volume: 175, Issue:5

    Topics: Clomipramine; Depressive Disorder; Humans; Male; Middle Aged; Pancytopenia

1987
High plasma concentrations of desmethylclomipramine after chronic administration of clomipramine to a poor metabolizer.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:1

    Topics: Allopurinol; Clomipramine; Debrisoquin; Depressive Disorder; Female; Humans; Hydroxylation; Kinetics

1987
Response to total sleep deprivation and clomipramine in endogenous depression.
    Journal of psychiatric research, 1987, Volume: 21, Issue:2

    Topics: Adult; Aged; Bipolar Disorder; Circadian Rhythm; Clomipramine; Combined Modality Therapy; Depressive

1987
Clomipramine and flupenthixol--additive antidepressants?
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 150

    Topics: Adult; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Flupenthixol; Humans; T

1987
Decreased plasma serotonin in melancholic patients: a study with clomipramine.
    Biological psychiatry, 1987, Volume: 22, Issue:12

    Topics: Aged; Blood Platelets; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; MMPI; P

1987
Clomipramine, tryptophan and lithium in combination for resistant endogenous depression: seven case studies.
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 151

    Topics: Adult; Antidepressive Agents, Tricyclic; Chronic Disease; Clomipramine; Depressive Disorder; Drug Re

1987
Cyproheptadine and antidepressant-induced anorgasmia.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Adult; Clomipramine; Cyproheptadine; Depressive Disorder; Female; Humans; Imipramine; Sexual Dysfunc

1986
Understanding the response lag to tricyclics. I. Application of pulse-loading regimens with intravenous clomipramine.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Injectio

1986
The dexamethasone suppression test in depressive and schizophrenic patients under controlled treatment conditions.
    European archives of psychiatry and neurological sciences, 1986, Volume: 235, Issue:5

    Topics: Adult; Clomipramine; Depressive Disorder; Dexamethasone; Double-Blind Method; Endorphins; Female; Hu

1986
[Atypical facial neuralgia or depressive facial pain. Diagnostic aspects of a well-demarcated form of masked depression].
    Fortschritte der Neurologie-Psychiatrie, 1986, Volume: 54, Issue:5

    Topics: Aged; Clomipramine; Depressive Disorder; Diagnosis, Differential; Drug Therapy, Combination; Facial

1986
Initial REM sleep suppression by clomipramine: a prognostic tool for treatment response in patients with a major depressive disorder.
    Biological psychiatry, 1986, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle

1986
Chlorimipramine--but not imipramine--rapidly reduces [3H]imipramine binding in human platelet membranes.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Amitriptyline; Blood Platelets; Cell Membrane; Clomipramine; Depressive Disorder; Humans; Imipramine

1986
Is there a relationship between response to total sleep deprivation and efficacy of clomipramine treatment in depressed patients?
    Acta psychiatrica Scandinavica, 1986, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Bipolar Disorder; Clomipramine; Depressive Disorder; Humans; Middle Aged; Prognos

1986
Nocturnal cataclysms with myoclonus: a new side effect of clomipramine.
    The American journal of psychiatry, 1986, Volume: 143, Issue:11

    Topics: Clomipramine; Depressive Disorder; Female; Humans; Middle Aged; Myoclonus; Sleep Wake Disorders

1986
Manic episode after propranolol withdrawal.
    The American journal of psychiatry, 1986, Volume: 143, Issue:12

    Topics: Bipolar Disorder; Clomipramine; Depressive Disorder; Female; Humans; Middle Aged; Propranolol; Subst

1986
[Plasma levels of clomipramine and declomipramine in patients with depression: a study of its correlation with therapeutic efficacy].
    Annales medico-psychologiques, 1986, Volume: 144, Issue:4

    Topics: Adolescent; Adult; Aged; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Human

1986
Autoscopic and drug-induced perceptual disturbances. A case report.
    Psychopathology, 1985, Volume: 18, Issue:5-6

    Topics: Clomipramine; Depressive Disorder; Diagnosis, Differential; Female; Hallucinations; Humans; Middle A

1985
Release of human neurophysin I during insulin-induced hypoglycemia in depressed patients is abolished after recovery with clomipramine treatment.
    Psychoneuroendocrinology, 1985, Volume: 10, Issue:1

    Topics: Blood Glucose; Clomipramine; Depressive Disorder; Female; Humans; Insulin; Middle Aged; Neurophysins

1985
Abnormal anterior pituitary responsiveness to hypothalamic hormones in depression: neurophysiological correlates and psychopharmacological effects.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Adult; Aged; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; Gonadotropin-

1985
The DST as a predictor of acute response to treatment with ECT, chlorimipramine, amitriptyline, and phenelzine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:3

    Topics: Amitriptyline; Clomipramine; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Female;

1986
Rapid achievement of antidepressant effect with intravenous chlorimipramine.
    The New England journal of medicine, 1985, Apr-25, Volume: 312, Issue:17

    Topics: Adult; Clomipramine; Depressive Disorder; Female; Humans; Infusions, Parenteral; Male; Time Factors

1985
Severe depression treatment: experience using maprotiline (Ludiomil) in combination with clomipramine (Anafranil).
    East African medical journal, 1985, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Anthracenes; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Humans

1985
Treatment of major depressive disorder with melancholia.
    Clinical therapeutics, 1985, Volume: 7, Issue:5

    Topics: Bromazepam; Clomipramine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Fluraze

1985
[Plasma levels of clomipramine and its metabolites in hospitalized depressed patients].
    Annales medico-psychologiques, 1985, Volume: 143, Issue:5

    Topics: Adult; Aged; Clomipramine; Combined Modality Therapy; Depressive Disorder; Female; Hospitalization;

1985