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clomipramine and Dementia

clomipramine has been researched along with Dementia in 4 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
" We report two cases in which paraphilias responded to treatment with clomipramine."7.69Clomipramine treatment of paraphilias in elderly demented patients. ( Kim, KY; Leo, RJ, 1995)
" We report two cases in which paraphilias responded to treatment with clomipramine."3.69Clomipramine treatment of paraphilias in elderly demented patients. ( Kim, KY; Leo, RJ, 1995)
"Depression is a highly prevalent concomitant of dementia."2.40Depression and dementia: comorbidities, identification, and treatment. ( Meyers, BS, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haddow, AM1
Harris, D1
Wilson, M1
Logie, H1
Leo, RJ1
Kim, KY1
Meyers, BS1
Turkington, D1
Geddes, J1

Reviews

1 review available for clomipramine and Dementia

ArticleYear
Depression and dementia: comorbidities, identification, and treatment.
    Journal of geriatric psychiatry and neurology, 1998,Winter, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cog

1998

Other Studies

3 other studies available for clomipramine and Dementia

ArticleYear
Clomipramine induced neuroleptic malignant syndrome and pyrexia of unknown origin.
    BMJ (Clinical research ed.), 2004, Dec-04, Volume: 329, Issue:7478

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Dementia; Fever of Unknown Origin; Humans; Male; Mid

2004
Clomipramine treatment of paraphilias in elderly demented patients.
    Journal of geriatric psychiatry and neurology, 1995, Volume: 8, Issue:2

    Topics: Age of Onset; Aged; Clomipramine; Dementia; Frontal Lobe; Humans; Male; Paraphilic Disorders; Treatm

1995
Delusional depression responding to clomipramine in Binswanger's disease.
    The Journal of nervous and mental disease, 1990, Volume: 178, Issue:7

    Topics: Clomipramine; Delusions; Dementia; Depression; Female; Humans; Middle Aged

1990