clomipramine has been researched along with Dementia Praecox in 36 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen." | 7.71 | Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine. ( Dewan, V; Zerjav-Lacombe, S, 2001) |
| "One schizophrenic and two manic-depressive patients who after the administration of zotepine, a new antipsychotic and antimanic drug, developed alopecia areata, a kind of autoimmune disease, are reported." | 7.68 | Three cases of alopecia areata induced by zotepine. ( Ishikura, T; Jibiki, I; Kubota, T, 1993) |
| "To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen." | 3.71 | Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine. ( Dewan, V; Zerjav-Lacombe, S, 2001) |
| "We report the cases of two patients fulfilling DSM-IV criteria for schizophrenia, who developed a marked depressive symptomatology in the first period of a treatment with clozapine, and were treated successfully with serotonergic drugs (paroxetine, clomipramine)." | 3.70 | Depressive symptomatology during clozapine treatment: two case reports. ( Altamura, AC; Bignotti, S; Curreli, R; Pioli, R; Tura, G, 1998) |
| "One schizophrenic and two manic-depressive patients who after the administration of zotepine, a new antipsychotic and antimanic drug, developed alopecia areata, a kind of autoimmune disease, are reported." | 3.68 | Three cases of alopecia areata induced by zotepine. ( Ishikura, T; Jibiki, I; Kubota, T, 1993) |
| "In a small series of patients, suffering from obsessional disorders, it was found that there seems to be a type of depression which occurs during the course of clomipramine therapy." | 3.65 | Depressive reactions in the course of clomipramine therapy used in the treatment of obsessional conditions. ( Capstick, N, 1975) |
| "Treatment with risperidone, though, results in considerably elevated plasma prolactin (PRL) levels which are not observed with other atypical neuroleptics, such as clozapine, indicating a differentiated action on receptors that are involved in PRL release, mainly dopaminergic and serotonergic." | 1.31 | Neuroendocrine serotonergic and dopaminergic responsivity in male schizophrenic patients during treatment with neuroleptics and after switch to risperidone. ( Hatzimanolis, J; Lykouras, L; Markianos, M, 2001) |
| "Clomipramine treatment was subsequently discontinued in two patients (off-on-off design), whereas it was discontinued and then reinstituted in three patients (off-on-off-on design)." | 1.29 | Clomipramine treatment of obsessive compulsive symptomatology in schizophrenic patients. ( Benjamin, J; Kaplan, Z; Zohar, J, 1993) |
| " Data in adult patients illustrate on the one hand possible causes of variability in plasma levels of haloperidol and, on the other hand, the fact that poor bioavailability is not the cause of lack of response in 'resistant' schizophrenic patients." | 1.26 | Clinical significance of monitoring plasma levels of psychotropic drugs. ( Morselli, PL; Zarifian, E, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (33.33) | 18.7374 |
| 1990's | 16 (44.44) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Margetić, B | 1 |
| Aukst-Margetić, B | 1 |
| Jakovljević, M | 1 |
| Horga, G | 1 |
| Horga, A | 1 |
| Baeza, I | 1 |
| Castro-Fornieles, J | 1 |
| Lázaro, L | 1 |
| Pons, A | 1 |
| Andrade, C | 1 |
| Safranko, I | 1 |
| Kordon, A | 1 |
| Broocks, A | 1 |
| Hohagen, F | 1 |
| Langer, G | 1 |
| Resch, F | 1 |
| Aschauer, H | 1 |
| Keshavan, MS | 1 |
| Koinig, G | 1 |
| Schönbeck, G | 1 |
| Dittrich, R | 1 |
| Pulman, J | 1 |
| Yassa, R | 1 |
| Ananth, J | 1 |
| Stroebel, CF | 1 |
| Szarek, BL | 1 |
| Glueck, BC | 1 |
| Hertrich, O | 1 |
| Berman, I | 1 |
| Sapers, BL | 1 |
| Chang, HH | 1 |
| Losonczy, MF | 1 |
| Schmildler, J | 1 |
| Green, AI | 1 |
| Bellino, S | 1 |
| Barzega, G | 1 |
| Bogetto, F | 1 |
| Maina, G | 1 |
| Ravizza, L | 1 |
| Kubota, T | 1 |
| Ishikura, T | 1 |
| Jibiki, I | 1 |
| Zohar, J | 1 |
| Kaplan, Z | 1 |
| Benjamin, J | 1 |
| Sewell, DD | 1 |
| Lopez, WM | 1 |
| Paulsen, J | 1 |
| Gilbert, P | 1 |
| Tejera, CA | 1 |
| Mayerhoff, DI | 1 |
| Ramos-Lorenzi, J | 1 |
| Escobar, R | 1 |
| Bernardo, M | 1 |
| Kurokawa, K | 1 |
| Tanino, R | 1 |
| Mahendran, R | 1 |
| Altamura, AC | 1 |
| Bignotti, S | 1 |
| Tura, G | 1 |
| Curreli, R | 1 |
| Pioli, R | 1 |
| Mottard, JP | 1 |
| de la Sablonnière, JF | 1 |
| Zerjav-Lacombe, S | 1 |
| Dewan, V | 1 |
| Markianos, M | 2 |
| Hatzimanolis, J | 2 |
| Lykouras, L | 2 |
| Christodoulou, GN | 1 |
| Morselli, PL | 1 |
| Zarifian, E | 1 |
| Huws, D | 1 |
| Groom, GV | 1 |
| Strian, F | 1 |
| Albert, W | 1 |
| Klicpera, C | 1 |
| Tissot, R | 1 |
| Capstick, N | 1 |
| Förstl, H | 1 |
| Pohlmann-Eden, B | 1 |
| Rothenberger, A | 1 |
| Bark, N | 1 |
| Lindenmayer, JP | 1 |
| Verdoux, H | 1 |
| Peyre, F | 1 |
| Bourgeois, M | 1 |
| Kim, SW | 1 |
| Dysken, MW | 1 |
| Möller, HJ | 1 |
| Kissling, W | 1 |
| Bottermann, P | 1 |
| Masciocchi, A | 1 |
| Reitano, S | 1 |
| Vanini, M | 1 |
| Cicchetti, V | 1 |
| Smulevich, AB | 1 |
| Vorob'ev, VIu | 1 |
| Zavidovskaia, GI | 1 |
| Lobova, EK | 1 |
| Balashova, MG | 1 |
2 reviews available for clomipramine and Dementia Praecox
| Article | Year |
|---|---|
[Obsessive-compulsive disorders in general practice. How the obsessive-compulsive neurotic is revealed by skin and hair].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age | 2003 |
The common pathophysiology of monaminergic psychoses: a new hypothesis.
Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrie | 1975 |
1 trial available for clomipramine and Dementia Praecox
| Article | Year |
|---|---|
Treatment of obsessive-compulsive symptoms in schizophrenic patients with clomipramine.
Topics: Adult; Clomipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Di | 1995 |
33 other studies available for clomipramine and Dementia Praecox
| Article | Year |
|---|---|
Aggravation of schizophrenia by clomipramine in a patient with comorbid obsessive-compulsive disorder.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Clozapine; Humans; Male; Middle Aged; Obsessive-Comp | 2008 |
Drug-induced speech dysfluency and myoclonus preceding generalized tonic-clonic seizures in an adolescent male with schizophrenia.
Topics: Adolescent; Antipsychotic Agents; Clomipramine; Clozapine; Epilepsy, Tonic-Clonic; Humans; Male; Myo | 2010 |
Serotonin reuptake inhibitor treatment of obsessive-compulsive symptoms in clozapine-medicated schizophrenia.
Topics: Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Clomipramine; Clozapine; Comorbidity; Cy | 2012 |
Reply to Dr Mahendran. We have not found reported cases of [obsessive-compulsive] OC arising from de novo with olanzapine treatment.
Topics: Adult; Benzodiazepines; Clomipramine; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Olanz | 2003 |
TSH-response patterns to TRH stimulation may indicate therapeutic mechanisms of antidepressant and neuroleptic drugs.
Topics: Adult; Clomipramine; Depressive Disorder; Female; Haloperidol; Humans; Prognosis; Psychiatric Status | 1984 |
Clomipramine treatment of repetitive behavior.
Topics: Adult; Clomipramine; Humans; Male; Middle Aged; Neurocognitive Disorders; Schizophrenia; Stereotyped | 1984 |
Use of clomipramine in treatment of obsessive-compulsive symptomatology.
Topics: Adolescent; Adult; Aged; Clomipramine; Female; Humans; Male; Middle Aged; MMPI; Obsessive-Compulsive | 1984 |
[Ataractic treatment in psychiatry and general medicine. Overview of preparations, 3].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Chlorprothixene; Clobaza | 1983 |
[Personality disorders and obsessive-compulsive disorder: critical analysis of the literature data and our studies].
Topics: Clomipramine; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Obsessive-Compulsive Disorder; P | 1995 |
Three cases of alopecia areata induced by zotepine.
Topics: Adult; Alopecia; Alopecia Areata; Antipsychotic Agents; Autoimmune Diseases; Carbamazepine; Clomipra | 1993 |
Clomipramine treatment of obsessive compulsive symptomatology in schizophrenic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Clomipramine; Drug Therapy, Combination; Female; Humans; Ma | 1993 |
Understanding and treating psychoses: advances in research and therapy.
Topics: Antipsychotic Agents; Clomipramine; Clozapine; Family; Humans; Receptors, Dopamine; Receptors, Serot | 1993 |
Treatment of obsessive-compulsive symptoms in schizophrenia with a neuroleptic-selective serotonin reuptake inhibitor combination: two case reports.
Topics: Adult; Aged; Antipsychotic Agents; Clomipramine; Drug Therapy, Combination; Fluoxetine; Humans; Male | 1994 |
Clomipramine for obsessive-compulsive symptoms in schizophrenia.
Topics: Adult; Clomipramine; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia | 1993 |
Schizophrenia, obsessive-compulsive disorder, and Tourette's syndrome: a case of triple comorbidity.
Topics: Adult; Basal Ganglia Diseases; Brain; Clomipramine; Comorbidity; Female; Haloperidol; Humans; Obsess | 1993 |
Effectiveness of clomipramine for obsessive-compulsive symptoms and chronic pain in two patients with schizophrenia.
Topics: Adult; Antidepressive Agents, Tricyclic; Chronic Disease; Clomipramine; Humans; Male; Obsessive-Comp | 1997 |
Obsessional symptoms associated with risperidone treatment.
Topics: Adult; Antipsychotic Agents; Clomipramine; Female; Humans; Obsessive Behavior; Psychiatric Status Ra | 1998 |
Depressive symptomatology during clozapine treatment: two case reports.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Age | 1998 |
Olanzapine-induced obsessive-compulsive disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clomipramine; Fluoxetine; Humans; Male; Obsessive-Comp | 1999 |
Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Humans; Male | 2001 |
Neuroendocrine serotonergic and dopaminergic responsivity in male schizophrenic patients during treatment with neuroleptics and after switch to risperidone.
Topics: Adult; Antipsychotic Agents; Clomipramine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; H | 2001 |
Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clomipramine; Clozapine; Haloperidol; | 2002 |
Clinical significance of monitoring plasma levels of psychotropic drugs.
Topics: Adult; Child; Chronic Disease; Clomipramine; Haloperidol; Humans; Mental Disorders; Parasympatholyti | 1979 |
Luteinizing hormone-releasing hormone and thyrotropin-releasing hormone stimulation studies in patients given clomipramine or 'depot' neuroleptics.
Topics: Clomipramine; Dibenzazepines; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophysea | 1977 |
Antidepressive treatment and mood swing patterns in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipra | 1979 |
Depressive reactions in the course of clomipramine therapy used in the treatment of obsessional conditions.
Topics: Adult; Aged; Amitriptyline; Clomipramine; Depression; Dibenzazepines; Female; Flupenthixol; Humans; | 1975 |
[Changes in somatosensory evoked potentials in pharmacogenic myoclonia].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Depressive Disor | 1992 |
Ineffectiveness of clomipramine for obsessive-compulsive symptoms in a patient with schizophrenia.
Topics: Adult; Chronic Disease; Clomipramine; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia; Sc | 1992 |
[Pseudo-schizophrenic forms of mood disorders].
Topics: Adult; Antidepressive Agents; Clomipramine; Diagnosis, Differential; Drug Therapy, Combination; Fema | 1991 |
Potential antidopaminergic effects of serotonin reuptake inhibitors.
Topics: Animals; Clomipramine; Dopamine Antagonists; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Rats | 1991 |
The dexamethasone suppression test in depressive and schizophrenic patients under controlled treatment conditions.
Topics: Adult; Clomipramine; Depressive Disorder; Dexamethasone; Double-Blind Method; Endorphins; Female; Hu | 1986 |
[Preliminary results of a controlled trial with sulpiride versus chlorimipramine in chronic schizophrenic patients with marked ideo-emotional poverty (author's transl)].
Topics: Affect; Anxiety; Chronic Disease; Clomipramine; Depression; Dibenzazepines; Humans; Mental Processes | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofura | 1974 |