clomipramine has been researched along with Deficiency, Mental in 15 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open, nonblind clinical trial, clomipramine reduced adventitious movements and compulsions in five previously medicated prepubertal boys with autistic disorder and severe mental retardation." | 9.07 | Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation. ( Aisemberg, P; Barnett, JY; Brasic, JR; Clark, A; Kaplan, D; Kowalik, S; Lafargue, RT; Sheitman, BB; Tsaltas, MO; Young, JG, 1994) |
| "In an open, nonblind clinical trial, clomipramine reduced adventitious movements and compulsions in five previously medicated prepubertal boys with autistic disorder and severe mental retardation." | 5.07 | Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation. ( Aisemberg, P; Barnett, JY; Brasic, JR; Clark, A; Kaplan, D; Kowalik, S; Lafargue, RT; Sheitman, BB; Tsaltas, MO; Young, JG, 1994) |
| "Clomipramine treatment was also associated with improvement in SIB intensity, frequency of stereotypy and compulsions, teacher ratings of stereotypy and social withdrawal, and frequency of staff intervention required for problem behaviors." | 2.68 | Clomipramine treatment for self-injurious behavior of individuals with mental retardation: a double-blind comparison with placebo. ( Bodfish, JW; Golden, RN; Lewis, MH; Parker, DE; Powell, SB, 1996) |
| "A case of a calendar savant with infantile autism and Tourette syndrome is presented." | 2.38 | A calendar savant with autism and Tourette syndrome. Response to treatment and thoughts on the interrelationships of these conditions. ( Nelson, EC; Pribor, EF, 1993) |
| " Clinical effects from the medications were measured in relation to and shown to be a function of dosage level." | 1.31 | Therapeutic effects and long-term efficacy of antidepressant medication for persons with developmental disabilities. Behavioral assessment in two cases of treatment-resistant aggression and self-injury. ( Blew, P; Luiselli, JK; Thibadeau, S, 2001) |
| "A boy with autistic disorder and severe mental retardation developed severe dyskinesias, including objective akathisia (probable) and tics, a month after discontinuation of at least two years of treatment with drugs block dopamine receptors." | 1.30 | Dyskinesias subside off all medication in a boy with autistic disorder and severe mental retardation. ( Ahmad, R; Ahn, SC; Aisemberg, P; Barnett, JY; Brasić, JR; Kaplan, D; Mendonça, Mde F; Nadrich, RH, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (73.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rana, F | 2 |
| Gormez, A | 2 |
| Varghese, S | 2 |
| Janowsky, DS | 1 |
| Shetty, M | 1 |
| Barnhill, J | 1 |
| Elamir, B | 1 |
| Davis, JM | 1 |
| Barak, Y | 1 |
| Ring, A | 1 |
| Levy, D | 1 |
| Granek, I | 1 |
| Szor, H | 1 |
| Elizur, A | 1 |
| Brasic, JR | 3 |
| Barnett, JY | 3 |
| Kaplan, D | 2 |
| Sheitman, BB | 2 |
| Aisemberg, P | 2 |
| Lafargue, RT | 1 |
| Kowalik, S | 1 |
| Clark, A | 1 |
| Tsaltas, MO | 2 |
| Young, JG | 1 |
| Nelson, EC | 1 |
| Pribor, EF | 1 |
| Helbing-Zwanenburg, B | 1 |
| Evenhuis, HM | 1 |
| Kamphuisen, HA | 1 |
| Holzer, JC | 1 |
| Jacobson, SA | 1 |
| Folstein, MF | 1 |
| Lewis, MH | 2 |
| Bodfish, JW | 2 |
| Powell, SB | 2 |
| Golden, RN | 2 |
| Parker, DE | 1 |
| Ahn, SC | 1 |
| Nadrich, RH | 1 |
| Ahmad, R | 1 |
| Mendonça, Mde F | 1 |
| Luiselli, JK | 1 |
| Blew, P | 1 |
| Thibadeau, S | 1 |
| Garber, HJ | 1 |
| McGonigle, JJ | 1 |
| Slomka, GT | 1 |
| Monteverde, E | 1 |
| Sugama, S | 1 |
| Kusano, K | 1 |
| Okazaki, M | 1 |
| Eto, Y | 1 |
3 reviews available for clomipramine and Deficiency, Mental
| Article | Year |
|---|---|
Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities.
Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Controlled Clinical Trials as Topic; Humans; | 2013 |
Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities: Abridged republication of a Cochrane systematic review.
Topics: Clomipramine; Humans; Intellectual Disability; Naltrexone; Narcotic Antagonists; Persons with Mental | 2014 |
A calendar savant with autism and Tourette syndrome. Response to treatment and thoughts on the interrelationships of these conditions.
Topics: Aptitude; Autistic Disorder; Clomipramine; Comorbidity; Humans; Intellectual Disability; Male; Middl | 1993 |
6 trials available for clomipramine and Deficiency, Mental
| Article | Year |
|---|---|
Disabling compulsions in 11 mentally retarded adults: an open trial of clomipramine SR.
Topics: Adult; Clomipramine; Comorbidity; Delayed-Action Preparations; Drug Administration Schedule; Female; | 1995 |
Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation.
Topics: Autistic Disorder; Child; Clomipramine; Humans; Intellectual Disability; Male; Movement Disorders; P | 1994 |
Clomipramine treatment for stereotype and related repetitive movement disorders associated with mental retardation.
Topics: Adolescent; Adult; Clomipramine; Cross-Over Studies; Double-Blind Method; Female; Humans; Intellectu | 1995 |
Clomipramine treatment for self-injurious behavior of individuals with mental retardation: a double-blind comparison with placebo.
Topics: Adult; Clomipramine; Cross-Over Studies; Double-Blind Method; Female; Humans; Intellectual Disabilit | 1996 |
Adverse effects of clomipramine.
Topics: Aggression; Akathisia, Drug-Induced; Autistic Disorder; Child; Clomipramine; Compulsive Behavior; Hu | 1997 |
Clomipramine treatment of stereotypic behaviors and self-injury in patients with developmental disabilities.
Topics: Adolescent; Child; Clomipramine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans | 1992 |
6 other studies available for clomipramine and Deficiency, Mental
| Article | Year |
|---|---|
Serotonergic antidepressant effects on aggressive, self-injurious and destructive/disruptive behaviours in intellectually disabled adults: a retrospective, open-label, naturalistic trial.
Topics: Adolescent; Adult; Aged; Aggression; Antidepressive Agents; Attention Deficit and Disruptive Behavio | 2005 |
[Prader-Willi syndrome and drowsiness; diagnostic attentiveness advised].
Topics: Cataplexy; Clomipramine; Diagnosis, Differential; Female; Humans; Intellectual Disability; Middle Ag | 1993 |
Treating compulsive self-mutilation in a mentally retarded patient.
Topics: Clomipramine; Clozapine; Compulsive Behavior; Drug Administration Schedule; Drug Therapy, Combinatio | 1996 |
Dyskinesias subside off all medication in a boy with autistic disorder and severe mental retardation.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Autistic Disorder; Child; Clomipramine; Dopamine Anta | 1997 |
Therapeutic effects and long-term efficacy of antidepressant medication for persons with developmental disabilities. Behavioral assessment in two cases of treatment-resistant aggression and self-injury.
Topics: Adolescent; Adult; Aggression; Antidepressive Agents; Behavior Therapy; Clomipramine; Combined Modal | 2001 |
[The neuroendocrinological examinations in mentally retarded boy with self-injurious behavior (SIB) and the effect of naloxone, clomipramine and sulpiride on SIB].
Topics: Child; Clomipramine; Humans; Intellectual Disability; Male; Naloxone; Pituitary Function Tests; Self | 1992 |