clomipramine has been researched along with Coma in 2 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clomipramine which has a stimulating effect on oxygen metabolism should be kept in reserve for the chronic phase of prolonged coma." | 1.26 | [Prolonged traumatic and vascular coma: prognostic and therapeutic indications based on hemodynamic and metabolic studies]. ( Baldy-Moulinier, M; Escuret, E; Frèrebeau, P; Passouant, P; Roquefeuil, B, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Attou, R | 1 |
| Reper, P | 1 |
| Baldy-Moulinier, M | 1 |
| Roquefeuil, B | 1 |
| Escuret, E | 1 |
| Frèrebeau, P | 1 |
| Passouant, P | 1 |
2 other studies available for clomipramine and Coma
| Article | Year |
|---|---|
Slow-release clomipramine acute poisoning with radio-opaque gastric bezoar.
Topics: Antidepressive Agents, Tricyclic; Bezoars; Clomipramine; Coma; Delayed-Action Preparations; Female; | 2013 |
[Prolonged traumatic and vascular coma: prognostic and therapeutic indications based on hemodynamic and metabolic studies].
Topics: Blood Gas Analysis; Brain; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; C | 1976 |