clomipramine has been researched along with Coagulation, Disseminated Intravascular in 2 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In spite of intensive therapy, an otherwise fit 34-year-old man died following the hyperpyrexial reaction to an interaction between tranylcypromine and clomipramine." | 3.67 | Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction. ( Tackley, RM; Tregaskis, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Power, BM | 1 |
| Pinder, M | 1 |
| Hackett, LP | 1 |
| Ilett, KF | 1 |
| Tackley, RM | 1 |
| Tregaskis, B | 1 |
2 other studies available for clomipramine and Coagulation, Disseminated Intravascular
| Article | Year |
|---|---|
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction.
Topics: Adult; Clomipramine; Disseminated Intravascular Coagulation; Drug Interactions; Fever; Humans; Male; | 1987 |