clomipramine has been researched along with Childhood Tic Disorders in 6 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The frequent comorbidity of OCD and Sydenham's chorea and similar postulates of basal ganglia dysfunction for both disorders suggest that Sydenham's chorea may serve as a medical model for OCD." | 2.39 | Childhood movement disorders and obsessive compulsive disorder. ( Leonard, HL; Swedo, SE, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McDougle, CJ | 1 |
| Goodman, WK | 1 |
| Price, LH | 1 |
| Wilens, TE | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wozniak, J | 1 |
| Connor, D | 1 |
| Swedo, SE | 2 |
| Leonard, HL | 2 |
| Rapoport, JL | 1 |
| Lenane, MC | 1 |
| Mataix-Cols, D | 1 |
| Rauch, SL | 1 |
| Manzo, PA | 1 |
| Jenike, MA | 1 |
| Baer, L | 1 |
| Ratzoni, G | 1 |
| Hermesh, H | 1 |
| Brandt, N | 1 |
| Lauffer, M | 1 |
| Munitz, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical, Neurocognitive and Neuroimaging Variables Associated With Response to Treatment in Patients With OCD[NCT03993535] | Phase 4 | 250 participants (Actual) | Interventional | 2018-10-10 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for clomipramine and Childhood Tic Disorders
| Article | Year |
|---|---|
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists | 1994 |
Childhood movement disorders and obsessive compulsive disorder.
Topics: Antipsychotic Agents; Child; Chorea; Clinical Trials as Topic; Clomipramine; Comorbidity; Female; Fl | 1994 |
Obsessive compulsive disorder in children and adolescents: issues in management.
Topics: Adolescent; Age Factors; Behavior Therapy; Child; Child, Preschool; Clomipramine; Comorbidity; Couns | 1993 |
3 other studies available for clomipramine and Childhood Tic Disorders
| Article | Year |
|---|---|
Combined pharmacotherapy: an emerging trend in pediatric psychopharmacology.
Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Child Psychiatry; | 1995 |
Use of factor-analyzed symptom dimensions to predict outcome with serotonin reuptake inhibitors and placebo in the treatment of obsessive-compulsive disorder.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Clomipramine; Comorbidity; Controlled Clinical Trials as T | 1999 |
Clomipramine efficacy for tics, obsessions, and compulsions in Tourette's syndrome and obsessive-compulsive disorder: a case study.
Topics: Adolescent; Clomipramine; Humans; Male; Obsessive-Compulsive Disorder; Stereotyped Behavior; Tic Dis | 1990 |