Page last updated: 2024-10-25

clomipramine and Brain Ischemia

clomipramine has been researched along with Brain Ischemia in 1 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system."1.30Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molaie, M1

Other Studies

1 other study available for clomipramine and Brain Ischemia

ArticleYear
Serotonin syndrome presenting with migrainelike stroke.
    Headache, 1997, Volume: 37, Issue:8

    Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi

1997