clomipramine has been researched along with Bradycardia in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " fluoxetine and chlorimipramine) or the 5-HT itself greatly reduced the reflex bradycardia induced by the systemically administered adrenaline." | 7.66 | Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats. ( Fan, YC; Lin, MT; Tsay, BL, 1980) |
| " fluoxetine and chlorimipramine) or the 5-HT itself greatly reduced the reflex bradycardia induced by the systemically administered adrenaline." | 3.66 | Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats. ( Fan, YC; Lin, MT; Tsay, BL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, MT | 1 |
| Tsay, BL | 1 |
| Fan, YC | 1 |
1 other study available for clomipramine and Bradycardia
| Article | Year |
|---|---|
Effects of 5-hydroxytryptamine, fluoxetine and chlorimipramine on reflex bradycardia in rats.
Topics: Animals; Blood Pressure; Bradycardia; Brain; Clomipramine; Dose-Response Relationship, Drug; Epineph | 1980 |